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The map label for this gene is corA [H]

Identifier: 157961546

GI number: 157961546

Start: 2093300

End: 2094247

Strand: Direct

Name: corA [H]

Synonym: Spea_1722

Alternate gene names: 157961546

Gene position: 2093300-2094247 (Clockwise)

Preceding gene: 157961545

Following gene: 157961551

Centisome position: 40.45

GC content: 41.03

Gene sequence:

>948_bases
ATGATAACAGCCTATGCCTATGAGGATCGTAAACTTACGATTATCGAATTGAGCATGAAGGACAACATCCCTCCCGGTAT
CATCTGGCTGGACTTATATAAACCTGACGAGCAGGAAAGAGAGTGGTTAAGTGGCTTTTCTGTTGAAGATGTGCAGGATG
AAGAGGACATCAATGAGATTGAGGCTTCAGCCCGTTTTTACCAGAATAAAGATGGACTGCACATCAACTCTTTGTTCCCG
CAACGTGCGGGGCAAGATGTCAAAGGGGTCAATGTCTCCTTTAATCTACGTAAAAACTTTCTGCTAACCATTCGTGAGGA
AGACGTAGGCCTGATCCGACTGCTGCGAAATTACCTAAGACTTGGTAAAATTGAAGCGAGTACACCTGAAACCCTATTAT
TAGAATTGTTTAATCTTAAAGTGGACTACCTCTCTGACTTAATTGAGGATGTATATACCGTTCTTGAGAATGTGAGCGAA
GAGGTGTTTAAGAATGAAGAGCTTGATAATGTATTTAAGCTTATCACTCGACAGGAAGATTCAAACGGTAAAATTCGTTT
AAGTCTGCTTGATACCCAACGTTCATTAAGGTTTATGCAGAAGTATTACCGTGCTCAACTATCTGATGATGAGCTTAAAG
ATCTGCGTGAAATGCTTTCAGATATCGAGTCTTTAATGCCTCATAGCCAGTTTATTTTCGATAAGCTGAACTTCTTACTC
GATGCAGCTATGGGTTTTAGTGGATTACAACAGAATAAAATCATTAAAATTTTCTCAGTTGCGGCAGTTGTCTTTTTACC
GCCAACGGTGATCGCAAGCTCTTACGGCATGAACTTTGTGAATATGCCTGAACTCGATTGGAGATTTGGTTACCCTATGG
CTATTGCTATGATGTTCGGTAGTGCGGCGGGAACCTACTTGTTCTTCAAGCGTAAAGGTTGGCTATAA

Upstream 100 bases:

>100_bases
TTTTCTTTTAGTGATCCCTTTGCAATACCACATTATAAGGTAGAATGGCCCACGTTTTTTTGTCCTAACGATTTGCTATA
TGTGTTTATAAGGAGGAGCT

Downstream 100 bases:

>100_bases
TACCAATTCAATCATCATTGGATTAAAAAAGCTCGCGACTGCGAGCTTTTTGCTATTACAGCAATAACCAAGTCTTATTT
AGTCCTTTTTCGTAAGGGCA

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MITAYAYEDRKLTIIELSMKDNIPPGIIWLDLYKPDEQEREWLSGFSVEDVQDEEDINEIEASARFYQNKDGLHINSLFP
QRAGQDVKGVNVSFNLRKNFLLTIREEDVGLIRLLRNYLRLGKIEASTPETLLLELFNLKVDYLSDLIEDVYTVLENVSE
EVFKNEELDNVFKLITRQEDSNGKIRLSLLDTQRSLRFMQKYYRAQLSDDELKDLREMLSDIESLMPHSQFIFDKLNFLL
DAAMGFSGLQQNKIIKIFSVAAVVFLPPTVIASSYGMNFVNMPELDWRFGYPMAIAMMFGSAAGTYLFFKRKGWL

Sequences:

>Translated_315_residues
MITAYAYEDRKLTIIELSMKDNIPPGIIWLDLYKPDEQEREWLSGFSVEDVQDEEDINEIEASARFYQNKDGLHINSLFP
QRAGQDVKGVNVSFNLRKNFLLTIREEDVGLIRLLRNYLRLGKIEASTPETLLLELFNLKVDYLSDLIEDVYTVLENVSE
EVFKNEELDNVFKLITRQEDSNGKIRLSLLDTQRSLRFMQKYYRAQLSDDELKDLREMLSDIESLMPHSQFIFDKLNFLL
DAAMGFSGLQQNKIIKIFSVAAVVFLPPTVIASSYGMNFVNMPELDWRFGYPMAIAMMFGSAAGTYLFFKRKGWL
>Mature_315_residues
MITAYAYEDRKLTIIELSMKDNIPPGIIWLDLYKPDEQEREWLSGFSVEDVQDEEDINEIEASARFYQNKDGLHINSLFP
QRAGQDVKGVNVSFNLRKNFLLTIREEDVGLIRLLRNYLRLGKIEASTPETLLLELFNLKVDYLSDLIEDVYTVLENVSE
EVFKNEELDNVFKLITRQEDSNGKIRLSLLDTQRSLRFMQKYYRAQLSDDELKDLREMLSDIESLMPHSQFIFDKLNFLL
DAAMGFSGLQQNKIIKIFSVAAVVFLPPTVIASSYGMNFVNMPELDWRFGYPMAIAMMFGSAAGTYLFFKRKGWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI2367297, Length=319, Percent_Identity=42.6332288401254, Blast_Score=250, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 36557; Mature: 36557

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITAYAYEDRKLTIIELSMKDNIPPGIIWLDLYKPDEQEREWLSGFSVEDVQDEEDINEI
CEEEEEECCCEEEEEEEEECCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHH
EASARFYQNKDGLHINSLFPQRAGQDVKGVNVSFNLRKNFLLTIREEDVGLIRLLRNYLR
HHHHHHHCCCCCEEEECCCHHHCCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHH
LGKIEASTPETLLLELFNLKVDYLSDLIEDVYTVLENVSEEVFKNEELDNVFKLITRQED
HCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
SNGKIRLSLLDTQRSLRFMQKYYRAQLSDDELKDLREMLSDIESLMPHSQFIFDKLNFLL
CCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DAAMGFSGLQQNKIIKIFSVAAVVFLPPTVIASSYGMNFVNMPELDWRFGYPMAIAMMFG
HHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
SAAGTYLFFKRKGWL
CCCCEEEEEEECCCC
>Mature Secondary Structure
MITAYAYEDRKLTIIELSMKDNIPPGIIWLDLYKPDEQEREWLSGFSVEDVQDEEDINEI
CEEEEEECCCEEEEEEEEECCCCCCCEEEEEEECCCHHHHHHHCCCCCCCCCCHHHHHHH
EASARFYQNKDGLHINSLFPQRAGQDVKGVNVSFNLRKNFLLTIREEDVGLIRLLRNYLR
HHHHHHHCCCCCEEEECCCHHHCCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHH
LGKIEASTPETLLLELFNLKVDYLSDLIEDVYTVLENVSEEVFKNEELDNVFKLITRQED
HCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCC
SNGKIRLSLLDTQRSLRFMQKYYRAQLSDDELKDLREMLSDIESLMPHSQFIFDKLNFLL
CCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
DAAMGFSGLQQNKIIKIFSVAAVVFLPPTVIASSYGMNFVNMPELDWRFGYPMAIAMMFG
HHHHCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHH
SAAGTYLFFKRKGWL
CCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]