Click here to switch to the map view.

The map label for this gene is gmhB [H]

Identifier: 157961537

GI number: 157961537

Start: 2079870

End: 2080424

Strand: Direct

Name: gmhB [H]

Synonym: Spea_1712

Alternate gene names: 157961537

Gene position: 2079870-2080424 (Clockwise)

Preceding gene: 157961534

Following gene: 157961543

Centisome position: 40.19

GC content: 43.24

Gene sequence:

>555_bases
GTGAATCGAGCGGTATTTTTAGACAGAGATGGCGTTATCAATCTAGACCATGGTTATGTACACCAAGTTGACGATTTTGA
ATATATAGACGGTGTGTTTGACGCGTGTGCATCTCTTAAAGAGATGGGATATTTGCTTGCTGTTGTTACCAACCAATCAG
GGATTGCTCGAGGAATGTACAGTGAAGAACAGTTTCATTCATTGACAGAGTGGATGGATTGGAACTTTGTCGATAAAGGC
GTTGAGCTAGACGGCATATATTACTGTCCTCATCATGCTGAAAAGGGCGTTGGCGAATATAAGATTGATTGTGATTGCCG
CAAACCAAAACCTGGCATGCTTAACTCAGCTGCACAATTCTTAAAAATCGATTTATCACAGTCTGTCATGGTCGGTGATA
AGCGTGACGATATGTTGGCTGCTGAGGCCGCAGGTATACCGACACGAATTCTTGTTAGAACAGGTAAATCTGTTACCGAT
GACGCGATTGCTGCTGCGACTGTCGTTTTAGATTCAATTGCAGATGTCCCCGCATATCTTTCGAGTCAAGCTTAG

Upstream 100 bases:

>100_bases
TTCATTACACGTTATTAGCTGCTTTATAGCAAGTTCACGGTGCATTTTGTTGTAATGAGTGAAATAATAATAGTCATTGC
ATATATAGAGAGAATGTATT

Downstream 100 bases:

>100_bases
CTCGTAAAGAATAGCTGTAAAGAGTTATCGACGAGGATTAGACTTCGAATGTATACGCCTCTAGCTCTAGGGGCGTTATT
GTTTCTAGCCCAGAACATCG

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MNRAVFLDRDGVINLDHGYVHQVDDFEYIDGVFDACASLKEMGYLLAVVTNQSGIARGMYSEEQFHSLTEWMDWNFVDKG
VELDGIYYCPHHAEKGVGEYKIDCDCRKPKPGMLNSAAQFLKIDLSQSVMVGDKRDDMLAAEAAGIPTRILVRTGKSVTD
DAIAAATVVLDSIADVPAYLSSQA

Sequences:

>Translated_184_residues
MNRAVFLDRDGVINLDHGYVHQVDDFEYIDGVFDACASLKEMGYLLAVVTNQSGIARGMYSEEQFHSLTEWMDWNFVDKG
VELDGIYYCPHHAEKGVGEYKIDCDCRKPKPGMLNSAAQFLKIDLSQSVMVGDKRDDMLAAEAAGIPTRILVRTGKSVTD
DAIAAATVVLDSIADVPAYLSSQA
>Mature_184_residues
MNRAVFLDRDGVINLDHGYVHQVDDFEYIDGVFDACASLKEMGYLLAVVTNQSGIARGMYSEEQFHSLTEWMDWNFVDKG
VELDGIYYCPHHAEKGVGEYKIDCDCRKPKPGMLNSAAQFLKIDLSQSVMVGDKRDDMLAAEAAGIPTRILVRTGKSVTD
DAIAAATVVLDSIADVPAYLSSQA

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=180, Percent_Identity=60.5555555555556, Blast_Score=238, Evalue=1e-64,
Organism=Escherichia coli, GI87082027, Length=148, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20246; Mature: 20246

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRAVFLDRDGVINLDHGYVHQVDDFEYIDGVFDACASLKEMGYLLAVVTNQSGIARGMY
CCCEEEEECCCEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHCCC
SEEQFHSLTEWMDWNFVDKGVELDGIYYCPHHAEKGVGEYKIDCDCRKPKPGMLNSAAQF
CHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHHH
LKIDLSQSVMVGDKRDDMLAAEAAGIPTRILVRTGKSVTDDAIAAATVVLDSIADVPAYL
HHHCCCCCEEECCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
SSQA
CCCC
>Mature Secondary Structure
MNRAVFLDRDGVINLDHGYVHQVDDFEYIDGVFDACASLKEMGYLLAVVTNQSGIARGMY
CCCEEEEECCCEEECCCCCEECCCCHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHCCC
SEEQFHSLTEWMDWNFVDKGVELDGIYYCPHHAEKGVGEYKIDCDCRKPKPGMLNSAAQF
CHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCEEEECCCCCCCCCHHHHHHHH
LKIDLSQSVMVGDKRDDMLAAEAAGIPTRILVRTGKSVTDDAIAAATVVLDSIADVPAYL
HHHCCCCCEEECCCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
SSQA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301; 12101286 [H]