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The map label for this gene is sohB [H]

Identifier: 157961477

GI number: 157961477

Start: 1996502

End: 1997530

Strand: Direct

Name: sohB [H]

Synonym: Spea_1651

Alternate gene names: 157961477

Gene position: 1996502-1997530 (Clockwise)

Preceding gene: 157961476

Following gene: 157961479

Centisome position: 38.58

GC content: 42.66

Gene sequence:

>1029_bases
TTGGAATTCCTGTACGAATATGGTTTATTTTTGGCCAAAGCGGTCACTATCGTCGCTGCGATTATTGCGGTAGTGATTGT
TGTCTTAGCGTCTTCTATGAAGCAGAAAGCTGAAAAGGGCGAGCTTAAGTTAACCAACCTAAGCGAAAACCTAGCATTAT
TGAAGCATGACTTAAAAGAAGAGTTATTATCTAAAAAAGCATTCAAGGCCTATGAGAAGCAATTAAAGGCTGACGAGAAA
GCCAAAGAGAAAGAGCAAAAAGATCAGGTTGAAGAAGCTGAGCCTAAAGTGTTTGTTGTCGACTTTAAAGGTAGCATTGA
TGCTGGCGAAGTGGCATCACTGCGTGAAGAGATCAGCGCTATCTTAGCTATCGCAGATAAGGGCGATGAAGTTATTGTTA
ATGTTGAGAGTGGCGGTGGCATGGTTCACGGTTACGGTTTGGCATCTAGCCAGCTTGACCGTTTAAGACAGGCTGAGATC
CCTCTGACTATCTGCGTTGACAAAGTGGCCGCCAGTGGCGGTTATATGATGGCCTGTGTTGCCAACAAAATTTATTCAGC
TCCTTTTGCTATCGTAGGTTCTATCGGCGTGGTGGCTCAGGTACCTAACTTTAATCGTTTATTGAAGAAGCACGATATCG
ATTATGAGCAACACACAGCAGGTGACTTTAAGCGTACTCTGACTATCTTTGGTGAAAATACCGATGAAGGGCGTGAGAAG
TTCCAAAAAGAGTTGGAAGAGACTCATGTGCTGTTTAAAGCGTTCATTGCCAAGTACCGTCCTGATTTAGATCTTGATAA
AGTGGCGACAGGTGAGCATTGGTATGGCCAACAAGCAATTGAGCTTGGCCTTGTCGATGAAATCGCCACAAGTGATGATG
TCATCATGAAGCTTGCTAATGAGCGTACCGTGATTAAGGTGCAGTATCAGCTTAAGAAAACATTATCAGATAAAATTGCC
CATGGTGCATCACTATCTTTTAATTCTATTTTCAATAAATTTGCTGAGAAGAACCAGCCACTCAAGTAA

Upstream 100 bases:

>100_bases
CAGCGAAAGCTGGGTTTTTTATTGCCATGTTTTATTGGTAAATAGACTGCTAGAATAGCTCCAAATTGAAGAGAGTGAAT
TGGTCTAGCTGGAGAGTATT

Downstream 100 bases:

>100_bases
TTGAGACTCGGTTTACCACCAGAAAAAACCTGCACTTTGCAGGTTTTTTTATGCTTAGAATTAAGTGGGTTAATTAGCTA
TGCCATTACACTAGAACCAT

Product: putative periplasmic protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MEFLYEYGLFLAKAVTIVAAIIAVVIVVLASSMKQKAEKGELKLTNLSENLALLKHDLKEELLSKKAFKAYEKQLKADEK
AKEKEQKDQVEEAEPKVFVVDFKGSIDAGEVASLREEISAILAIADKGDEVIVNVESGGGMVHGYGLASSQLDRLRQAEI
PLTICVDKVAASGGYMMACVANKIYSAPFAIVGSIGVVAQVPNFNRLLKKHDIDYEQHTAGDFKRTLTIFGENTDEGREK
FQKELEETHVLFKAFIAKYRPDLDLDKVATGEHWYGQQAIELGLVDEIATSDDVIMKLANERTVIKVQYQLKKTLSDKIA
HGASLSFNSIFNKFAEKNQPLK

Sequences:

>Translated_342_residues
MEFLYEYGLFLAKAVTIVAAIIAVVIVVLASSMKQKAEKGELKLTNLSENLALLKHDLKEELLSKKAFKAYEKQLKADEK
AKEKEQKDQVEEAEPKVFVVDFKGSIDAGEVASLREEISAILAIADKGDEVIVNVESGGGMVHGYGLASSQLDRLRQAEI
PLTICVDKVAASGGYMMACVANKIYSAPFAIVGSIGVVAQVPNFNRLLKKHDIDYEQHTAGDFKRTLTIFGENTDEGREK
FQKELEETHVLFKAFIAKYRPDLDLDKVATGEHWYGQQAIELGLVDEIATSDDVIMKLANERTVIKVQYQLKKTLSDKIA
HGASLSFNSIFNKFAEKNQPLK
>Mature_342_residues
MEFLYEYGLFLAKAVTIVAAIIAVVIVVLASSMKQKAEKGELKLTNLSENLALLKHDLKEELLSKKAFKAYEKQLKADEK
AKEKEQKDQVEEAEPKVFVVDFKGSIDAGEVASLREEISAILAIADKGDEVIVNVESGGGMVHGYGLASSQLDRLRQAEI
PLTICVDKVAASGGYMMACVANKIYSAPFAIVGSIGVVAQVPNFNRLLKKHDIDYEQHTAGDFKRTLTIFGENTDEGREK
FQKELEETHVLFKAFIAKYRPDLDLDKVATGEHWYGQQAIELGLVDEIATSDDVIMKLANERTVIKVQYQLKKTLSDKIA
HGASLSFNSIFNKFAEKNQPLK

Specific function: Multicopy suppressor of the htrA (degP) null phenotype. It is possibly a protease, not essential for bacterial viability [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=348, Percent_Identity=55.1724137931034, Blast_Score=363, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002142
- InterPro:   IPR013703 [H]

Pfam domain/function: PF01343 Peptidase_S49; PF08496 Peptidase_S49_N [H]

EC number: 3.4.21.-

Molecular weight: Translated: 37889; Mature: 37889

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFLYEYGLFLAKAVTIVAAIIAVVIVVLASSMKQKAEKGELKLTNLSENLALLKHDLKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHH
ELLSKKAFKAYEKQLKADEKAKEKEQKDQVEEAEPKVFVVDFKGSIDAGEVASLREEISA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHH
ILAIADKGDEVIVNVESGGGMVHGYGLASSQLDRLRQAEIPLTICVDKVAASGGYMMACV
HHHHCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHHCCCHHEEHHHHHCCCCEEHHHH
ANKIYSAPFAIVGSIGVVAQVPNFNRLLKKHDIDYEQHTAGDFKRTLTIFGENTDEGREK
HHHHHHCCHHHHHCCHHEEECCCHHHHHHHHCCCHHHHCCCCHHEEEEEECCCCHHHHHH
FQKELEETHVLFKAFIAKYRPDLDLDKVATGEHWYGQQAIELGLVDEIATSDDVIMKLAN
HHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCC
ERTVIKVQYQLKKTLSDKIAHGASLSFNSIFNKFAEKNQPLK
CCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEFLYEYGLFLAKAVTIVAAIIAVVIVVLASSMKQKAEKGELKLTNLSENLALLKHDLKE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHH
ELLSKKAFKAYEKQLKADEKAKEKEQKDQVEEAEPKVFVVDFKGSIDAGEVASLREEISA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHH
ILAIADKGDEVIVNVESGGGMVHGYGLASSQLDRLRQAEIPLTICVDKVAASGGYMMACV
HHHHCCCCCEEEEEEECCCCEEEECCCCHHHHHHHHHHCCCHHEEHHHHHCCCCEEHHHH
ANKIYSAPFAIVGSIGVVAQVPNFNRLLKKHDIDYEQHTAGDFKRTLTIFGENTDEGREK
HHHHHHCCHHHHHCCHHEEECCCHHHHHHHHCCCHHHHCCCCHHEEEEEECCCCHHHHHH
FQKELEETHVLFKAFIAKYRPDLDLDKVATGEHWYGQQAIELGLVDEIATSDDVIMKLAN
HHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHCC
ERTVIKVQYQLKKTLSDKIAHGASLSFNSIFNKFAEKNQPLK
CCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1885549; 9097039; 9278503; 3029379 [H]