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The map label for this gene is ttdR [H]

Identifier: 157961434

GI number: 157961434

Start: 1947713

End: 1948666

Strand: Reverse

Name: ttdR [H]

Synonym: Spea_1608

Alternate gene names: 157961434

Gene position: 1948666-1947713 (Counterclockwise)

Preceding gene: 157961437

Following gene: 157961431

Centisome position: 37.66

GC content: 44.86

Gene sequence:

>954_bases
ATGATCACCACAGAAGATCTAAGATTCATCACCACAATCGCCAGCCATAAAACCCTAGCCGATGCGGCTAGGACGTTAAA
TATTACTCCGCCGTCGGTAACGCTTAGATTGCAACATATTGAAAAAAAACTGTCGATCAAACTTATTCAGCGCCCCTCAA
GAGTCGTGAGCCTAACGGAAGAAGGACAACTTTTACTGGATAAAGGCTTGCCTATTCTGCGTGGACTCGATGAACTACAA
GAACAGCTGGATGAGCTTAAGGAGCATGTTTGTGGCAAGCTGAGAGTATTAGCCCCCTTAGGTTTTGGTAATGATTATAT
CGCGCCCTTGCTTGGCGAATACAAGCTCCTACATCCTCAGCTAGATATCGAACTTGAGTTATCCGATAACCCCAATTGGT
CTAGTCATCATAAATGGGACATCATTATCTATATAGGTGCGCTCAATGATTCCTCATTGAAAATGATAACTTTGGCTAAA
AACCAAAGATTTGTCTGTGCCTCCCCAAAATACCTTGAGCAAATGGGAGAACCAAAGGAGCCTCAAGAGCTACTCAAACA
TCGATGCATCGCATTAAGGGAAAACAACGAAGATGTGACCTTGTGGCCGTTTACCAAGCTGTTACATGAGAAATTGTCAC
ATGACAAGCTTTCCAACGACAAGCCAACCGATGACAAACTTGAAATGATCAGGATCACGCCGACACTGGCAAGCAACGAG
GGCCGCGTCATTAAAGATTGGGCTATGGCAGGGTTAGGCGTCATTATGCGATCTGAGTGGGATGTGCAGCCGCAGATCAA
CAACGGTGAACTTGTGCGTATATTAGCCGATTATTCACTACCGAACGCCAATATAGTTGCGTTATTAAGTAGTCCAGAGA
AAGAACGTTCGGCTCGTATTTCTGGCTTTATTCAGCTCCTCAAACAGCGACTAACCCCGCTTCCTTGGAAGTAA

Upstream 100 bases:

>100_bases
ACGTGAGCAATATCAAACCAGCGTGTAGAACAAGAGTATCCAAGAAGTTTGTTTTGTTTTACATTAATACTTATTAAGGT
ATAGATTAGGTTAAAACTAA

Downstream 100 bases:

>100_bases
GCAATCGATACATTTGAACGACTAAAGCCGCCAAATAAAGTAGAGCTAATACAACGAAACTAATACAACAGACGGCGATA
ACTGAGCATCAGCACTTTTG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MITTEDLRFITTIASHKTLADAARTLNITPPSVTLRLQHIEKKLSIKLIQRPSRVVSLTEEGQLLLDKGLPILRGLDELQ
EQLDELKEHVCGKLRVLAPLGFGNDYIAPLLGEYKLLHPQLDIELELSDNPNWSSHHKWDIIIYIGALNDSSLKMITLAK
NQRFVCASPKYLEQMGEPKEPQELLKHRCIALRENNEDVTLWPFTKLLHEKLSHDKLSNDKPTDDKLEMIRITPTLASNE
GRVIKDWAMAGLGVIMRSEWDVQPQINNGELVRILADYSLPNANIVALLSSPEKERSARISGFIQLLKQRLTPLPWK

Sequences:

>Translated_317_residues
MITTEDLRFITTIASHKTLADAARTLNITPPSVTLRLQHIEKKLSIKLIQRPSRVVSLTEEGQLLLDKGLPILRGLDELQ
EQLDELKEHVCGKLRVLAPLGFGNDYIAPLLGEYKLLHPQLDIELELSDNPNWSSHHKWDIIIYIGALNDSSLKMITLAK
NQRFVCASPKYLEQMGEPKEPQELLKHRCIALRENNEDVTLWPFTKLLHEKLSHDKLSNDKPTDDKLEMIRITPTLASNE
GRVIKDWAMAGLGVIMRSEWDVQPQINNGELVRILADYSLPNANIVALLSSPEKERSARISGFIQLLKQRLTPLPWK
>Mature_317_residues
MITTEDLRFITTIASHKTLADAARTLNITPPSVTLRLQHIEKKLSIKLIQRPSRVVSLTEEGQLLLDKGLPILRGLDELQ
EQLDELKEHVCGKLRVLAPLGFGNDYIAPLLGEYKLLHPQLDIELELSDNPNWSSHHKWDIIIYIGALNDSSLKMITLAK
NQRFVCASPKYLEQMGEPKEPQELLKHRCIALRENNEDVTLWPFTKLLHEKLSHDKLSNDKPTDDKLEMIRITPTLASNE
GRVIKDWAMAGLGVIMRSEWDVQPQINNGELVRILADYSLPNANIVALLSSPEKERSARISGFIQLLKQRLTPLPWK

Specific function: Positive regulator required for L-tartrate-dependent anaerobic growth on glycerol. Induces expression of the ttdA-ttdB- ygjE operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789440, Length=312, Percent_Identity=30.7692307692308, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI87081978, Length=307, Percent_Identity=28.6644951140065, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1786401, Length=313, Percent_Identity=25.5591054313099, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI145693193, Length=301, Percent_Identity=25.5813953488372, Blast_Score=104, Evalue=6e-24,
Organism=Escherichia coli, GI1787128, Length=282, Percent_Identity=21.9858156028369, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789639, Length=291, Percent_Identity=24.7422680412371, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1786448, Length=266, Percent_Identity=25.187969924812, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787589, Length=188, Percent_Identity=22.8723404255319, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 36056; Mature: 36056

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTEDLRFITTIASHKTLADAARTLNITPPSVTLRLQHIEKKLSIKLIQRPSRVVSLTE
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEHHHHHHHHHHHHHCCCCCEEEECC
EGQLLLDKGLPILRGLDELQEQLDELKEHVCGKLRVLAPLGFGNDYIAPLLGEYKLLHPQ
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCEEECCC
LDIELELSDNPNWSSHHKWDIIIYIGALNDSSLKMITLAKNQRFVCASPKYLEQMGEPKE
EEEEEEECCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCEEEECCCHHHHHCCCCCC
PQELLKHRCIALRENNEDVTLWPFTKLLHEKLSHDKLSNDKPTDDKLEMIRITPTLASNE
HHHHHHHHCEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCC
GRVIKDWAMAGLGVIMRSEWDVQPQINNGELVRILADYSLPNANIVALLSSPEKERSARI
CCEEHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHH
SGFIQLLKQRLTPLPWK
HHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MITTEDLRFITTIASHKTLADAARTLNITPPSVTLRLQHIEKKLSIKLIQRPSRVVSLTE
CCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEHHHHHHHHHHHHHCCCCCEEEECC
EGQLLLDKGLPILRGLDELQEQLDELKEHVCGKLRVLAPLGFGNDYIAPLLGEYKLLHPQ
CCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHCCCEEECCC
LDIELELSDNPNWSSHHKWDIIIYIGALNDSSLKMITLAKNQRFVCASPKYLEQMGEPKE
EEEEEEECCCCCCCCCCCEEEEEEEEECCCCCEEEEEEECCCEEEECCCHHHHHCCCCCC
PQELLKHRCIALRENNEDVTLWPFTKLLHEKLSHDKLSNDKPTDDKLEMIRITPTLASNE
HHHHHHHHCEEEECCCCCEEEHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEEECCC
GRVIKDWAMAGLGVIMRSEWDVQPQINNGELVRILADYSLPNANIVALLSSPEKERSARI
CCEEHHHHHHHHHHEEECCCCCCCCCCCCCEEEEEEECCCCCCCEEEEECCCCHHHHHHH
SGFIQLLKQRLTPLPWK
HHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]