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The map label for this gene is trpD [H]

Identifier: 157961414

GI number: 157961414

Start: 1926917

End: 1927993

Strand: Reverse

Name: trpD [H]

Synonym: Spea_1588

Alternate gene names: 157961414

Gene position: 1927993-1926917 (Counterclockwise)

Preceding gene: 157961415

Following gene: 157961413

Centisome position: 37.26

GC content: 51.16

Gene sequence:

>1077_bases
ATGATGACTCAAACCGAAATCAAGCAGCTTGAAATTAAAAGCTCTGAAACGTTAATCGAATCCCTTTATCGCGGTGAAAG
CCTAAACCGCACTGATGCAAAAACGTTATTTAGCCGTATCATTCAAGGTGAGATGAATGAAGTCACCATGGCAGGAATGT
TAGTCGCCATGAAAATGCGCGGCGAAACCATCGATGAAATATCGGGTGCGGCCGATGCACTTCGTACGGCTGCAAAATCC
TTTCCGACGCCGAGTGAATCGACCGTCAGTCAAGGCATTGTCGATATTGTAGGCACTGGTGGCGATGGTCACAACACTAT
CAATATCTCTACCACGGCGGCGTTTGTTGCCGCGGCGGCTGGAGCTAAGGTGGCTAAACACGGTAACCGCAGCGTATCGA
GCAAATCGGGTTCATCAGACTTACTGGCGCAATTTGGTATCGATTTAACCATGGCACCAGAAACGGCACGTGACTGCTTA
GACGAGCTAGGACTGTGCTTCTTGTTTGCGCCACACTATCATGGCGGCGTGGCCCACGCGGTGCCTGTGCGTCAGGCACT
AAAAACCCGTACTCTATTTAATGTGTTGGGGCCGCTCATTAACCCGTCTCGCCCAGACTTTATGCTGCTTGGTGTGTATA
GCCCAGAGCTGGTAGCCCCCATCGCACAAGTCGTAAAAGCACTCGGTATTAAACGCGCCATGGTGGTGCACGGTAGCGGC
CTCGATGAAGTCGCGCTTCACGGCGATACCTTAGTGCATGAGCTTAAAGATGGCGCTATCAGCGAGTACCGTATTACTCC
AGCCATGCTTGGCGTACCAGAGGCTAAGCTTACTGATTTAGAAGGCGGCGCACCTGAAGAAAATGCTGATTACACCCGCG
CCATATTGCAAGGCAAAGGAAAAGCTGCCCATATGAATGCGGTTGCTATCAATGCAGGCTGCGCCCTCTATGTGGCAGGC
ATTTGCACTGACATCAAATCTGGCACAGCGTTAGCACTCGAGACCATTAACAGCGGCAAAGCCTACAAATTATTGACCCA
GCTGGCTAACGCTAGCCAAGCTGGCAAAGGAGCCTAA

Upstream 100 bases:

>100_bases
TCAATTTTAACCACTTTAGGCAGCCAGTTATTGGTACAGAGCTTAGATTACCTCGCCAGTGCTTTAGCACAAGATAGCCA
AGACAACATCAAAGGATAAG

Downstream 100 bases:

>100_bases
TGTGAGCACGGATTTAAGAGAAGAACCAGCAATAAAAGAAAGCAATGTACTGACTAAAATTGTCGATACTAAGGCGGCAC
ATATCGCCTCACTCAAGCAG

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 358; Mature: 358

Protein sequence:

>358_residues
MMTQTEIKQLEIKSSETLIESLYRGESLNRTDAKTLFSRIIQGEMNEVTMAGMLVAMKMRGETIDEISGAADALRTAAKS
FPTPSESTVSQGIVDIVGTGGDGHNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMAPETARDCL
DELGLCFLFAPHYHGGVAHAVPVRQALKTRTLFNVLGPLINPSRPDFMLLGVYSPELVAPIAQVVKALGIKRAMVVHGSG
LDEVALHGDTLVHELKDGAISEYRITPAMLGVPEAKLTDLEGGAPEENADYTRAILQGKGKAAHMNAVAINAGCALYVAG
ICTDIKSGTALALETINSGKAYKLLTQLANASQAGKGA

Sequences:

>Translated_358_residues
MMTQTEIKQLEIKSSETLIESLYRGESLNRTDAKTLFSRIIQGEMNEVTMAGMLVAMKMRGETIDEISGAADALRTAAKS
FPTPSESTVSQGIVDIVGTGGDGHNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMAPETARDCL
DELGLCFLFAPHYHGGVAHAVPVRQALKTRTLFNVLGPLINPSRPDFMLLGVYSPELVAPIAQVVKALGIKRAMVVHGSG
LDEVALHGDTLVHELKDGAISEYRITPAMLGVPEAKLTDLEGGAPEENADYTRAILQGKGKAAHMNAVAINAGCALYVAG
ICTDIKSGTALALETINSGKAYKLLTQLANASQAGKGA
>Mature_358_residues
MMTQTEIKQLEIKSSETLIESLYRGESLNRTDAKTLFSRIIQGEMNEVTMAGMLVAMKMRGETIDEISGAADALRTAAKS
FPTPSESTVSQGIVDIVGTGGDGHNTINISTTAAFVAAAAGAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMAPETARDCL
DELGLCFLFAPHYHGGVAHAVPVRQALKTRTLFNVLGPLINPSRPDFMLLGVYSPELVAPIAQVVKALGIKRAMVVHGSG
LDEVALHGDTLVHELKDGAISEYRITPAMLGVPEAKLTDLEGGAPEENADYTRAILQGKGKAAHMNAVAINAGCALYVAG
ICTDIKSGTALALETINSGKAYKLLTQLANASQAGKGA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=334, Percent_Identity=53.8922155688623, Blast_Score=315, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6320561, Length=274, Percent_Identity=34.6715328467153, Blast_Score=134, Evalue=3e-32,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 37461; Mature: 37461

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTQTEIKQLEIKSSETLIESLYRGESLNRTDAKTLFSRIIQGEMNEVTMAGMLVAMKMR
CCCHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GETIDEISGAADALRTAAKSFPTPSESTVSQGIVDIVGTGGDGHNTINISTTAAFVAAAA
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCCCEEEEEHHHHHHHHHH
GAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMAPETARDCLDELGLCFLFAPHYHGGVAHA
CHHHHHCCCCCCCCCCCCHHHHHHHCCCEEECCHHHHHHHHHCCEEEEECCCCCCCCHHH
VPVRQALKTRTLFNVLGPLINPSRPDFMLLGVYSPELVAPIAQVVKALGIKRAMVVHGSG
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCC
LDEVALHGDTLVHELKDGAISEYRITPAMLGVPEAKLTDLEGGAPEENADYTRAILQGKG
CCHHHHCHHHHHHHHHCCCCCCEEECHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
KAAHMNAVAINAGCALYVAGICTDIKSGTALALETINSGKAYKLLTQLANASQAGKGA
CEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MMTQTEIKQLEIKSSETLIESLYRGESLNRTDAKTLFSRIIQGEMNEVTMAGMLVAMKMR
CCCHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHC
GETIDEISGAADALRTAAKSFPTPSESTVSQGIVDIVGTGGDGHNTINISTTAAFVAAAA
CCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEECCCCCCCEEEEEHHHHHHHHHH
GAKVAKHGNRSVSSKSGSSDLLAQFGIDLTMAPETARDCLDELGLCFLFAPHYHGGVAHA
CHHHHHCCCCCCCCCCCCHHHHHHHCCCEEECCHHHHHHHHHCCEEEEECCCCCCCCHHH
VPVRQALKTRTLFNVLGPLINPSRPDFMLLGVYSPELVAPIAQVVKALGIKRAMVVHGSG
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCEEEEEECCC
LDEVALHGDTLVHELKDGAISEYRITPAMLGVPEAKLTDLEGGAPEENADYTRAILQGKG
CCHHHHCHHHHHHHHHCCCCCCEEECHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCC
KAAHMNAVAINAGCALYVAGICTDIKSGTALALETINSGKAYKLLTQLANASQAGKGA
CEEEEEEEEECCCHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA