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The map label for this gene is nagA [H]

Identifier: 157961349

GI number: 157961349

Start: 1850469

End: 1851605

Strand: Reverse

Name: nagA [H]

Synonym: Spea_1523

Alternate gene names: 157961349

Gene position: 1851605-1850469 (Counterclockwise)

Preceding gene: 157961358

Following gene: 157961348

Centisome position: 35.78

GC content: 43.01

Gene sequence:

>1137_bases
ATGATTACGACAGTGATAGCCGAGCAAGTATTTAATGGTCGAGAGATCTTGAAAGATCAGCCAATCACTTTCCAAGATGG
CAAAGTGATCGCTTTTGATAGCGTAAATAATGCAAAAGAATTCAAAATTTCGGGATTATTAACCCCAGGCTTTATTGACG
TTCAAGTTAATGGTGGTGGCGGCTATTTGTTTAATCAGCAAACTCACTTAACGGCTCTCGAAGCTATGGTGCATGCCCAC
AGTCGTTATGGCACCACATGGCTACTTCCAACGCTAATTACCAGTGATTTAACCACATTAAACAATGCCGCAAATACTAT
CGCTGACGCCATTAAAAAACGGCTTCCAGGCGTTATAGGTGTTCACTTTGAAGGACCGCATATCAGCGAGCCAAAAAAAG
GGATCCACAATAGCCAGCACATTAGGGCCCTAAGTGATCAAGAAATGGCAGTGTATTGCCGTAACGACCTAGGTATCAAA
GTGGTCACCATCGCACCAGAGTGTGTGACAACAGAGCAAGTAAAATCGCTAATAGCACACAATGTTAAAGTATGTTTAGG
CCACTCCAATGCAAGCTTTGAACTCACTCAAGCAGCGCTTGATGCTGGCGCAATCGGGTTTACTCATCTATTTAATGCTA
TGTCGCCACTCACATCCCGAGACCCCAATATGCTCGGCGCTGCACTTCTTGATAAGAATAGCTGGTGTGGCCTTATCTTA
GACGGCCATCACGTGCATCCTGCATCGGCAAAGCTTGCTACCAAAGTTAAAAGCAATGGAAAAATGATGTTAGTGACAGA
TGCAATGTCTACCATTGGTAGCAACCAACAAACATTTGAGTTTGATGGTCATCAAATACAACTCAGCACTAATAAGTTAA
CCAGCCAAACCGGTCAATTAGCAGGCTCAGCATTAGATATGATAACGGCGGTCAACAACGCCCAAACCATGCTAGATATT
TCACTAGAAGAGTCTCTAAGAATGGCAAGTGTGTATCCAGCAGACTTTCTCGGCATTAATACAGCCACGCAATTACTTGC
AATAGGCGCAAATGCAGACTTCACCGTACTTGAAAAGAGTAGTCAAACAAGTTTACACGTAAGCCAAACATGGATTGATG
GCAAACAAATATTTTAA

Upstream 100 bases:

>100_bases
CACAACGGATAGCACAACAGGTTAGCCTTACACTCACTCAGCGCCGGATCATAGAACCGCATCAAGTGGGATTATCTTCA
GCAATAGAGCCTAATTAATA

Downstream 100 bases:

>100_bases
TTTAAATAAAGGATTACCATGCAAAAACTAACTGGGTTAATCGCAGCACCACATACTCCATTTGATATTAATGGTGATGT
TAATCTGCCTGTTATCGATC

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MITTVIAEQVFNGREILKDQPITFQDGKVIAFDSVNNAKEFKISGLLTPGFIDVQVNGGGGYLFNQQTHLTALEAMVHAH
SRYGTTWLLPTLITSDLTTLNNAANTIADAIKKRLPGVIGVHFEGPHISEPKKGIHNSQHIRALSDQEMAVYCRNDLGIK
VVTIAPECVTTEQVKSLIAHNVKVCLGHSNASFELTQAALDAGAIGFTHLFNAMSPLTSRDPNMLGAALLDKNSWCGLIL
DGHHVHPASAKLATKVKSNGKMMLVTDAMSTIGSNQQTFEFDGHQIQLSTNKLTSQTGQLAGSALDMITAVNNAQTMLDI
SLEESLRMASVYPADFLGINTATQLLAIGANADFTVLEKSSQTSLHVSQTWIDGKQIF

Sequences:

>Translated_378_residues
MITTVIAEQVFNGREILKDQPITFQDGKVIAFDSVNNAKEFKISGLLTPGFIDVQVNGGGGYLFNQQTHLTALEAMVHAH
SRYGTTWLLPTLITSDLTTLNNAANTIADAIKKRLPGVIGVHFEGPHISEPKKGIHNSQHIRALSDQEMAVYCRNDLGIK
VVTIAPECVTTEQVKSLIAHNVKVCLGHSNASFELTQAALDAGAIGFTHLFNAMSPLTSRDPNMLGAALLDKNSWCGLIL
DGHHVHPASAKLATKVKSNGKMMLVTDAMSTIGSNQQTFEFDGHQIQLSTNKLTSQTGQLAGSALDMITAVNNAQTMLDI
SLEESLRMASVYPADFLGINTATQLLAIGANADFTVLEKSSQTSLHVSQTWIDGKQIF
>Mature_378_residues
MITTVIAEQVFNGREILKDQPITFQDGKVIAFDSVNNAKEFKISGLLTPGFIDVQVNGGGGYLFNQQTHLTALEAMVHAH
SRYGTTWLLPTLITSDLTTLNNAANTIADAIKKRLPGVIGVHFEGPHISEPKKGIHNSQHIRALSDQEMAVYCRNDLGIK
VVTIAPECVTTEQVKSLIAHNVKVCLGHSNASFELTQAALDAGAIGFTHLFNAMSPLTSRDPNMLGAALLDKNSWCGLIL
DGHHVHPASAKLATKVKSNGKMMLVTDAMSTIGSNQQTFEFDGHQIQLSTNKLTSQTGQLAGSALDMITAVNNAQTMLDI
SLEESLRMASVYPADFLGINTATQLLAIGANADFTVLEKSSQTSLHVSQTWIDGKQIF

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=428, Percent_Identity=31.7757009345794, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI224922791, Length=425, Percent_Identity=31.2941176470588, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1786892, Length=377, Percent_Identity=33.9522546419098, Blast_Score=209, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17553768, Length=399, Percent_Identity=30.8270676691729, Blast_Score=128, Evalue=6e-30,
Organism=Drosophila melanogaster, GI19920392, Length=381, Percent_Identity=31.758530183727, Blast_Score=163, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281361140, Length=393, Percent_Identity=30.5343511450382, Blast_Score=159, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 40735; Mature: 40735

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITTVIAEQVFNGREILKDQPITFQDGKVIAFDSVNNAKEFKISGLLTPGFIDVQVNGGG
CCHHHHHHHHHCCHHHHCCCCCEEECCCEEEEECCCCCCEEEEEEEECCCEEEEEEECCC
GYLFNQQTHLTALEAMVHAHSRYGTTWLLPTLITSDLTTLNNAANTIADAIKKRLPGVIG
EEEECCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VHFEGPHISEPKKGIHNSQHIRALSDQEMAVYCRNDLGIKVVTIAPECVTTEQVKSLIAH
EEECCCCCCCCHHCCCCCHHEEECCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHC
NVKVCLGHSNASFELTQAALDAGAIGFTHLFNAMSPLTSRDPNMLGAALLDKNSWCGLIL
CEEEEEECCCCCEEEHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHEEECCCCCEEEEE
DGHHVHPASAKLATKVKSNGKMMLVTDAMSTIGSNQQTFEFDGHQIQLSTNKLTSQTGQL
ECCEECCCCHHHHHHHCCCCCEEEEEECHHHHCCCCEEEEECCCEEEEECCHHHHHHHHH
AGSALDMITAVNNAQTMLDISLEESLRMASVYPADFLGINTATQLLAIGANADFTVLEKS
HHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCHHHCCCCCHHEEEEECCCCCEEEEECC
SQTSLHVSQTWIDGKQIF
CCCEEEEEEEEECCCCCC
>Mature Secondary Structure
MITTVIAEQVFNGREILKDQPITFQDGKVIAFDSVNNAKEFKISGLLTPGFIDVQVNGGG
CCHHHHHHHHHCCHHHHCCCCCEEECCCEEEEECCCCCCEEEEEEEECCCEEEEEEECCC
GYLFNQQTHLTALEAMVHAHSRYGTTWLLPTLITSDLTTLNNAANTIADAIKKRLPGVIG
EEEECCCHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
VHFEGPHISEPKKGIHNSQHIRALSDQEMAVYCRNDLGIKVVTIAPECVTTEQVKSLIAH
EEECCCCCCCCHHCCCCCHHEEECCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHC
NVKVCLGHSNASFELTQAALDAGAIGFTHLFNAMSPLTSRDPNMLGAALLDKNSWCGLIL
CEEEEEECCCCCEEEHHHHHCCCCHHHHHHHHHHCCCCCCCCCHHHHEEECCCCCEEEEE
DGHHVHPASAKLATKVKSNGKMMLVTDAMSTIGSNQQTFEFDGHQIQLSTNKLTSQTGQL
ECCEECCCCHHHHHHHCCCCCEEEEEECHHHHCCCCEEEEECCCEEEEECCHHHHHHHHH
AGSALDMITAVNNAQTMLDISLEESLRMASVYPADFLGINTATQLLAIGANADFTVLEKS
HHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCHHHCCCCCHHEEEEECCCCCEEEEECC
SQTSLHVSQTWIDGKQIF
CCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9301118; 10952301 [H]