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The map label for this gene is nanR [H]

Identifier: 157961343

GI number: 157961343

Start: 1842935

End: 1843639

Strand: Direct

Name: nanR [H]

Synonym: Spea_1517

Alternate gene names: 157961343

Gene position: 1842935-1843639 (Clockwise)

Preceding gene: 157961341

Following gene: 157961344

Centisome position: 35.62

GC content: 40.43

Gene sequence:

>705_bases
ATGCCAATTACTATTAAACGTCCTGTTGAACGAAAAAAACTTTCAGAAACCGTTGAAGAAGAATTGGAACAGATGATACG
CCAAGGTGAAATAGCCGAAGGTGAAGCGCTGCCGTCTGAAAGAGAGTTAATGGCGGCATTTGGAGTGGGCAGGCCTTCAA
TTCGCGATGCCTTGTCAGCACTTGCACGCAAAGGCTTAGTTAAAATTAGCAGCGGTGAACGAACTCGTGTGAGTAGACCT
TCTCCTGAAACCATTATTTCTGAGCTATCAGGAATGTCAAAAGACTTTCTATCGCAGCCTAACGGATTGCAATATTTTGA
TCAGCTAAGAAGCTTCTTTGAATCGAGCTTAGTGCGCCATGCGGCAGAGTTTGCAACAAGTGAACAAATTGAAGAGTTAG
AAAAAGCGGTCGCATTAAATGGCAAAGCAATAGATAACGAAAGCCAATTTAAAAAAACCGATATCTATTTTCACCATGTC
ATAGCATCTATACCTGGCAACCCCATTTTTTTGGCCATTCACCAAGCGCTAGTTGATTGGGTTATTGATGCTAGACCGGC
TAAAACCAACGTTAAAGAGTTAAACGCTAAAAGCCATCAAGACCATGTCGATATTTTAGAATGCATTAAAAATCGTGATG
TAGAGGGAGCGGATAAAAAGTTAACTCAACACATACAATATGTATTTGATAAGTATTACGATTAG

Upstream 100 bases:

>100_bases
GATGTGGCATCTATTTGGGATAATTTTGTATACATTTATTGCACCACTGGTATGATAGCTAGATAGGTATAAAACTTGTT
AGGTGCTAAAGGAACTTCGA

Downstream 100 bases:

>100_bases
TAGATAAATATTTTCATGCTCAAGCAGTCTTTTCAGTAAAGGTTGCTTATCTATTTTTGAGCTTAATTAAAACATGAATT
ATTCATTCTAAGGGCTATCT

Product: transcriptional regulator NanR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MPITIKRPVERKKLSETVEEELEQMIRQGEIAEGEALPSERELMAAFGVGRPSIRDALSALARKGLVKISSGERTRVSRP
SPETIISELSGMSKDFLSQPNGLQYFDQLRSFFESSLVRHAAEFATSEQIEELEKAVALNGKAIDNESQFKKTDIYFHHV
IASIPGNPIFLAIHQALVDWVIDARPAKTNVKELNAKSHQDHVDILECIKNRDVEGADKKLTQHIQYVFDKYYD

Sequences:

>Translated_234_residues
MPITIKRPVERKKLSETVEEELEQMIRQGEIAEGEALPSERELMAAFGVGRPSIRDALSALARKGLVKISSGERTRVSRP
SPETIISELSGMSKDFLSQPNGLQYFDQLRSFFESSLVRHAAEFATSEQIEELEKAVALNGKAIDNESQFKKTDIYFHHV
IASIPGNPIFLAIHQALVDWVIDARPAKTNVKELNAKSHQDHVDILECIKNRDVEGADKKLTQHIQYVFDKYYD
>Mature_233_residues
PITIKRPVERKKLSETVEEELEQMIRQGEIAEGEALPSERELMAAFGVGRPSIRDALSALARKGLVKISSGERTRVSRPS
PETIISELSGMSKDFLSQPNGLQYFDQLRSFFESSLVRHAAEFATSEQIEELEKAVALNGKAIDNESQFKKTDIYFHHVI
ASIPGNPIFLAIHQALVDWVIDARPAKTNVKELNAKSHQDHVDILECIKNRDVEGADKKLTQHIQYVFDKYYD

Specific function: Transcriptional repressor of the nan operon that encodes proteins involved in sialic acid utilization [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789621, Length=229, Percent_Identity=59.3886462882096, Blast_Score=278, Evalue=2e-76,
Organism=Escherichia coli, GI1789353, Length=186, Percent_Identity=25.8064516129032, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26420; Mature: 26289

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPITIKRPVERKKLSETVEEELEQMIRQGEIAEGEALPSERELMAAFGVGRPSIRDALSA
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
LARKGLVKISSGERTRVSRPSPETIISELSGMSKDFLSQPNGLQYFDQLRSFFESSLVRH
HHHCCCEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
AAEFATSEQIEELEKAVALNGKAIDNESQFKKTDIYFHHVIASIPGNPIFLAIHQALVDW
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VIDARPAKTNVKELNAKSHQDHVDILECIKNRDVEGADKKLTQHIQYVFDKYYD
HHCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PITIKRPVERKKLSETVEEELEQMIRQGEIAEGEALPSERELMAAFGVGRPSIRDALSA
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHH
LARKGLVKISSGERTRVSRPSPETIISELSGMSKDFLSQPNGLQYFDQLRSFFESSLVRH
HHHCCCEEECCCCCCCCCCCCHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHHH
AAEFATSEQIEELEKAVALNGKAIDNESQFKKTDIYFHHVIASIPGNPIFLAIHQALVDW
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
VIDARPAKTNVKELNAKSHQDHVDILECIKNRDVEGADKKLTQHIQYVFDKYYD
HHCCCCCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA