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The map label for this gene is rmlC [H]

Identifier: 157961246

GI number: 157961246

Start: 1725678

End: 1726247

Strand: Direct

Name: rmlC [H]

Synonym: Spea_1420

Alternate gene names: 157961246

Gene position: 1725678-1726247 (Clockwise)

Preceding gene: 157961245

Following gene: 157961259

Centisome position: 33.35

GC content: 45.61

Gene sequence:

>570_bases
ATGATGAAACTCATACCTACTTCTATTCCTGATGTGTTGCTGTTTGAGCCGCAAGTATTTGGTGATGCTCGTGGTTTTTT
TATGGAAACCTTTCGTCAATCAGAGTTTGAGGCGCTGTTTGCTGAAGTGGGCATGGTTTGCCCGAGCTTTGTGCAAGAGA
ATATGAGTCGTTCGGCTAAAAATGTACTACGTGGGCTGCATTATCAAACGCTGCAACCGCAAGGTAAATTGATCCGAGTT
ACTGCAGGTAGCATTTTCGATGTTGCCGTCGACCTTCGTAAAGGTTCTAAAACCTATGGCCAGTGGTTTGGGCAAACCTT
ATCTGCTGAAAATAGGCTGCAATTGTATATTCCTCCGGGGTTCGCCCACGGCTTTTTAACCTTAAGCGATCATGCTGACA
TTATCTATAAATGCACCGATTACTATGCACCCGAGCATGAAAGAACCATTGCGTGGAATGATCCTCAATTAAACATCCAA
TGGCCGATAGGCGAGGGCGTGAAGCCGATTTTGTCGGAAAAAGATGGGAAAGCTGAGAAGGTCCTAGGTTCTAGGGAAAG
CAGGTCCTAG

Upstream 100 bases:

>100_bases
TAGGTCCTAGAACCTTGTTTATTCAGTGAGCTAGCGAACGCTCCGTAGTCTGTAAGCGAAGCGTTCGTCTTCGCTTTCTT
TAACCTTATTTTAAAAGAAC

Downstream 100 bases:

>100_bases
GTTAAAGCAAAGACGTTACAAGCTAAGACGGAAAAGCGGAGCGGCCTGCGGCCTACAGAACGCTACGCTGACGGTTAAAG
CATAGAAGGTCCTAGATCCT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MMKLIPTSIPDVLLFEPQVFGDARGFFMETFRQSEFEALFAEVGMVCPSFVQENMSRSAKNVLRGLHYQTLQPQGKLIRV
TAGSIFDVAVDLRKGSKTYGQWFGQTLSAENRLQLYIPPGFAHGFLTLSDHADIIYKCTDYYAPEHERTIAWNDPQLNIQ
WPIGEGVKPILSEKDGKAEKVLGSRESRS

Sequences:

>Translated_189_residues
MMKLIPTSIPDVLLFEPQVFGDARGFFMETFRQSEFEALFAEVGMVCPSFVQENMSRSAKNVLRGLHYQTLQPQGKLIRV
TAGSIFDVAVDLRKGSKTYGQWFGQTLSAENRLQLYIPPGFAHGFLTLSDHADIIYKCTDYYAPEHERTIAWNDPQLNIQ
WPIGEGVKPILSEKDGKAEKVLGSRESRS
>Mature_189_residues
MMKLIPTSIPDVLLFEPQVFGDARGFFMETFRQSEFEALFAEVGMVCPSFVQENMSRSAKNVLRGLHYQTLQPQGKLIRV
TAGSIFDVAVDLRKGSKTYGQWFGQTLSAENRLQLYIPPGFAHGFLTLSDHADIIYKCTDYYAPEHERTIAWNDPQLNIQ
WPIGEGVKPILSEKDGKAEKVLGSRESRS

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=177, Percent_Identity=54.2372881355932, Blast_Score=186, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17550412, Length=176, Percent_Identity=43.1818181818182, Blast_Score=138, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 21349; Mature: 21349

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLIPTSIPDVLLFEPQVFGDARGFFMETFRQSEFEALFAEVGMVCPSFVQENMSRSAK
CCCCCCCCCCCEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
NVLRGLHYQTLQPQGKLIRVTAGSIFDVAVDLRKGSKTYGQWFGQTLSAENRLQLYIPPG
HHHHHCCCCEECCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCC
FAHGFLTLSDHADIIYKCTDYYAPEHERTIAWNDPQLNIQWPIGEGVKPILSEKDGKAEK
CCCCEEEECCCCCEEEEECCCCCCCCCCEEEECCCEEEEECCCCCCCCHHHCCCCCCHHH
VLGSRESRS
HHCCCCCCC
>Mature Secondary Structure
MMKLIPTSIPDVLLFEPQVFGDARGFFMETFRQSEFEALFAEVGMVCPSFVQENMSRSAK
CCCCCCCCCCCEEEECCHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
NVLRGLHYQTLQPQGKLIRVTAGSIFDVAVDLRKGSKTYGQWFGQTLSAENRLQLYIPPG
HHHHHCCCCEECCCCCEEEEECCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCC
FAHGFLTLSDHADIIYKCTDYYAPEHERTIAWNDPQLNIQWPIGEGVKPILSEKDGKAEK
CCCCEEEECCCCCEEEEECCCCCCCCCCEEEECCCEEEEECCCCCCCCHHHCCCCCCHHH
VLGSRESRS
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]