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The map label for this gene is ugd [H]

Identifier: 157961244

GI number: 157961244

Start: 1722866

End: 1724032

Strand: Direct

Name: ugd [H]

Synonym: Spea_1418

Alternate gene names: 157961244

Gene position: 1722866-1724032 (Clockwise)

Preceding gene: 157961242

Following gene: 157961245

Centisome position: 33.29

GC content: 40.7

Gene sequence:

>1167_bases
ATGAAAATTGCTATAGCAGGGACAGGCTATGTTGGTCTGTCAAACGCGGTATTGTTAGCACAAAAGAACACCGTAATGGC
TGTTGATATTGTTGCTGAAAAAGTGGAGATGATTAACCTAGGTCAATCACCTATAGCAGATGTAGAGATAGAAGATTACC
TACAAAATCATAAGCTAAATTTAACTGCAACGCTTGATAAGCAATTAGCCTATCAAGATGCAGATTATGTGGTTATTGCC
ACACCGACAGATTACGACACTGAATCAAATTATTTTAATACATCGTCGGTTGAAGCCGTTATTCAAGATGTGTTAGCTAT
TAATCCAAATGCAGTTATGGTGATTAAGTCGACTGTACCAGTCGGTTATACGGAGTCGGTGAAACAAAAGTTCGATACTC
AAAATATTATTTTCTCACCTGAGTTTTTACGGGAAGGCCGAGCGCTTTACGATAACTTGCATCCATCGCGTATTATCATT
GGTGAGCGCTCTGATCGCGCTGAAGTGTTTGCTAACTTACTTGCAAGTGCGGCGATTAAAGAAAATATCGATATTCTTTT
TACTGACTCGACCGAAGCCGAAGCGGTTAAGCTTTTTTCGAATACCTACCTTGCAATGCGAGTCGCCTACTTTAATGAGT
TAGACAGTTATGCCGAGTCTCACGGTTTGGATTCACGCCAAATTATTGAAGGCGTTGGTCTAGACCCTCGTATTGGTAGC
CATTATAACAATCCATCATTTGGCTATGGTGGCTATTGCCTACCAAAAGACACTAAACAGCTTCGTGCAAACTATGCGGA
CGTACCGAATAGTCTTATTAGCGCGATTGTTGATGCTAACTCTACCCGTAAAGATTTTATTGCAGATTCTATTATTAATA
AGCAACCGAAAGTTGTTGGTATCTACCGTTTAATCATGAAGTCGGGTTCAGATAACTTCCGTGCATCTTCTATTCAGGGC
ATTATGAAGCGCATTAAAGCTAAGGGTATTGAGGTTGTAGTATTTGAGCCCGTACTTAACGAGCCTGAGTTCTTTAACTC
TCGAGTGATGCAAGATCTGAATGAATTTAAACAGATCTCAGATGTCATAGTATCAAACCGTATGGTTGACGAGCTGGCCG
ATGTCGCGGCTAAAGTTTATACCCGCGACTTGTTTGGTTCGGATTAA

Upstream 100 bases:

>100_bases
GGATCTCGTTTCTTCATCGCGGTAAAAATGTGAGCCCAAAACAAGACATTTTCCTAGTTGAGTGGTATTTTACGCGGATA
TATTTTTTTAAGGTTTAAAG

Downstream 100 bases:

>100_bases
TAACAAGCTAAGAAGGTCCTAGGTTCTAGGAAAGCAGGTTCTAGGAAAAGGCTAAGATGGTACAAGCTAAGAAGAGCGCT
GCGCTTCTAGGACGTGACAG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIAIAGTGYVGLSNAVLLAQKNTVMAVDIVAEKVEMINLGQSPIADVEIEDYLQNHKLNLTATLDKQLAYQDADYVVIA
TPTDYDTESNYFNTSSVEAVIQDVLAINPNAVMVIKSTVPVGYTESVKQKFDTQNIIFSPEFLREGRALYDNLHPSRIII
GERSDRAEVFANLLASAAIKENIDILFTDSTEAEAVKLFSNTYLAMRVAYFNELDSYAESHGLDSRQIIEGVGLDPRIGS
HYNNPSFGYGGYCLPKDTKQLRANYADVPNSLISAIVDANSTRKDFIADSIINKQPKVVGIYRLIMKSGSDNFRASSIQG
IMKRIKAKGIEVVVFEPVLNEPEFFNSRVMQDLNEFKQISDVIVSNRMVDELADVAAKVYTRDLFGSD

Sequences:

>Translated_388_residues
MKIAIAGTGYVGLSNAVLLAQKNTVMAVDIVAEKVEMINLGQSPIADVEIEDYLQNHKLNLTATLDKQLAYQDADYVVIA
TPTDYDTESNYFNTSSVEAVIQDVLAINPNAVMVIKSTVPVGYTESVKQKFDTQNIIFSPEFLREGRALYDNLHPSRIII
GERSDRAEVFANLLASAAIKENIDILFTDSTEAEAVKLFSNTYLAMRVAYFNELDSYAESHGLDSRQIIEGVGLDPRIGS
HYNNPSFGYGGYCLPKDTKQLRANYADVPNSLISAIVDANSTRKDFIADSIINKQPKVVGIYRLIMKSGSDNFRASSIQG
IMKRIKAKGIEVVVFEPVLNEPEFFNSRVMQDLNEFKQISDVIVSNRMVDELADVAAKVYTRDLFGSD
>Mature_388_residues
MKIAIAGTGYVGLSNAVLLAQKNTVMAVDIVAEKVEMINLGQSPIADVEIEDYLQNHKLNLTATLDKQLAYQDADYVVIA
TPTDYDTESNYFNTSSVEAVIQDVLAINPNAVMVIKSTVPVGYTESVKQKFDTQNIIFSPEFLREGRALYDNLHPSRIII
GERSDRAEVFANLLASAAIKENIDILFTDSTEAEAVKLFSNTYLAMRVAYFNELDSYAESHGLDSRQIIEGVGLDPRIGS
HYNNPSFGYGGYCLPKDTKQLRANYADVPNSLISAIVDANSTRKDFIADSIINKQPKVVGIYRLIMKSGSDNFRASSIQG
IMKRIKAKGIEVVVFEPVLNEPEFFNSRVMQDLNEFKQISDVIVSNRMVDELADVAAKVYTRDLFGSD

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=408, Percent_Identity=25.7352941176471, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI296040438, Length=305, Percent_Identity=27.2131147540984, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI296040443, Length=258, Percent_Identity=26.7441860465116, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=74.4845360824742, Blast_Score=605, Evalue=1e-174,
Organism=Escherichia coli, GI48994968, Length=278, Percent_Identity=26.6187050359712, Blast_Score=75, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17560350, Length=377, Percent_Identity=26.2599469496021, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17136908, Length=374, Percent_Identity=27.2727272727273, Blast_Score=118, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 43002; Mature: 43002

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAIAGTGYVGLSNAVLLAQKNTVMAVDIVAEKVEMINLGQSPIADVEIEDYLQNHKLN
CEEEEEECCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEE
LTATLDKQLAYQDADYVVIATPTDYDTESNYFNTSSVEAVIQDVLAINPNAVMVIKSTVP
EEEEECHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC
VGYTESVKQKFDTQNIIFSPEFLREGRALYDNLHPSRIIIGERSDRAEVFANLLASAAIK
CCCHHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
ENIDILFTDSTEAEAVKLFSNTYLAMRVAYFNELDSYAESHGLDSRQIIEGVGLDPRIGS
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
HYNNPSFGYGGYCLPKDTKQLRANYADVPNSLISAIVDANSTRKDFIADSIINKQPKVVG
CCCCCCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHH
IYRLIMKSGSDNFRASSIQGIMKRIKAKGIEVVVFEPVLNEPEFFNSRVMQDLNEFKQIS
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
DVIVSNRMVDELADVAAKVYTRDLFGSD
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIAIAGTGYVGLSNAVLLAQKNTVMAVDIVAEKVEMINLGQSPIADVEIEDYLQNHKLN
CEEEEEECCCCCCCCEEEEEECCCEEEEHHHHHHHHHHCCCCCCCCCCCHHHHHHCCCEE
LTATLDKQLAYQDADYVVIATPTDYDTESNYFNTSSVEAVIQDVLAINPNAVMVIKSTVP
EEEEECHHHHHCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC
VGYTESVKQKFDTQNIIFSPEFLREGRALYDNLHPSRIIIGERSDRAEVFANLLASAAIK
CCCHHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHH
ENIDILFTDSTEAEAVKLFSNTYLAMRVAYFNELDSYAESHGLDSRQIIEGVGLDPRIGS
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCC
HYNNPSFGYGGYCLPKDTKQLRANYADVPNSLISAIVDANSTRKDFIADSIINKQPKVVG
CCCCCCCCCCCEECCCCHHHHHHHHHCCCHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHH
IYRLIMKSGSDNFRASSIQGIMKRIKAKGIEVVVFEPVLNEPEFFNSRVMQDLNEFKQIS
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHH
DVIVSNRMVDELADVAAKVYTRDLFGSD
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]