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The map label for this gene is flhA [H]

Identifier: 157961203

GI number: 157961203

Start: 1671339

End: 1673438

Strand: Direct

Name: flhA [H]

Synonym: Spea_1375

Alternate gene names: 157961203

Gene position: 1671339-1673438 (Clockwise)

Preceding gene: 157961202

Following gene: 157961204

Centisome position: 32.3

GC content: 49.81

Gene sequence:

>2100_bases
ATGGAACTTAAAGCAAGTCTAGGCCAATTAAAACAGATAAAGCCTGCACATTTAAAAGGTATTGGTACGCCTTTATTGGT
CTTAGCCGCACTGGCTATGATTATTTTACCTATGCCAGCGTTCCTGCTCGATATCCTTTTCACCTTCAATATTGCACTGG
CGTTAGTGGTGCTTTTGGTGGCGATTTACAGCGACCGACCACTTGATTTCGCCGCATTCCCTACCGTTTTACTGGTCGCT
ACCTTACTCCGGCTCGCCCTAAACGTTGCCTCCACCCGTGTGGTACTGCTAGAAGGCCATAACGGTGGTGATGCCGCCGG
TAAAGTGATTGAAGCGTTCGGCTCGGTGGTGATTGGTGGCAACTATGCCGTGGGTCTAGTGGTGTTTTTAATCCTTATTA
TCATCAACTTTGCGGTGGTAACAAAAGGTGCTGGGCGAATATCTGAGGTGAGTGCTCGCTTCACCCTCGACGCCATGCCG
GGCAAGCAGATGGCAATCGATGCCGACTTAAATGCCGGGCTACTCTCCCAAGAAGAAGCTAGGGCCCGCCGCGCCGAAGT
GACCCGTGAAGCCGACTTTTACGGTGCCATGGATGGTGCGTCAAAATTTGTAAAAGGCGATGCGGTCGCCGGTATCTTAA
TTCTGGTTATTAATATCGTCGGCGGCTTTATCATTGGTATCGCTCAGCATGACCTGTCTTTCTCTTCTGCCGTTGAAATT
TATACCCTATTAACGATTGGTGATGGCCTAGTGGCGCAGATCCCCGGTCTGCTCTTATCTATTGCAGCGGCTTTGATGGT
GACCCGTCAAAATGAATCGGGCGACATGGGCGAGATGGTAATGGGACAGATGTTTGACAGTCCCAAGTCTCTAGCTATTG
CTTCGGCAGTGATGTTAGTGATGGGAATAGTGCCTGGTATGCCGCATCTTGTGTTCTTATCATGCGCTGCTGTATCTGGC
GCCGCGGCTTATTTTATTAAGAAAAAGAAAGACACCGACCGAGAACGTGCCCTAGAGCTTGCGAAGAGTGGCCCTGTAGA
GCCAAGAGACATTCAGCCAAAAGAGTTGAGTTGGGACGATGTGCAGCATGTCGACACCATTGGCCTAGAAGTGGGCTACC
GCTTAATTCCACTAGTTGATAAAGGCCAAGGCGGCGAGCTACTTGGCCGTATTAAAGGGGTGCGTAAGAAGCTGTCGCAG
GAGTTAGGCTTCTTGGTGCCAGCGGTGCATATTCGCGATAATTTAGATCTGTCCCCCAATGCCTATCGGATCTCTCTTAT
GGGCGTAAGCTCGGGTGAGGCAGAAATTCGTCATGACTGTGAACTGGCGATTAACCCGGGTCAAGTTTATGGCAAGCTCG
ACGGTATCGAAACCAAAGATCCGGCTTTTGGCCTAGATGCGGTTTGGATTGCCCCAGAGATGCGCGAGCATGCACAGACC
TTAGGTTATACCGTCGTGGATGCATCCACGGTAGTGGCTACACACATCAGTCAGCTGCTGACCAATAATGCTGCTAAGCT
ACTTGGTTATGAAGAAGTACAGCAGTTACTTGAGATGCTAGGCAAGCATTCACCTAAGTTGGTTGATGGATTTATTCCCG
ATGTGATGCCACTTGGGACAGTCGTGAAGGTGATGCAGAACCTGCTGAATGAAGGGGTGTCAATTCGCGACATGAAGACC
ATAGTACAAACTTTGCTTGAGTATGGAACCAAGAGTAGTGACACCGAGGTGTTGACCGCTGCCGTTCGTATTGCGCTAAA
ACGTATGATAGTGCAAGAGATCAGTGGACCAGAGCTTGAAATCCCCGTCATAACTTTGGCGCCAGAGTTGGAACAGATGT
TGCATCAGTCTATGCAGGCGACGGGAGGAGATGGTCCAAATATCGAACCAAGCCTCGCAGAACGCATGCAGAAGTCATTA
GTGGACGCCACACAGCGTCAAGAAATGGTGGGGCAACCTGCGATTTTACTGACATCAGGCATGTTACGTTCAACCTTATC
GCGATTCGTTAAGCATACGATCCCTAATTTACGGGTGATTTCATATCAGGAAGTCCCCGACGAGAAGCAGATACGCATCG
TCTCGGCAGTGGGTCAGTAG

Upstream 100 bases:

>100_bases
GTTAATGGCTTTCAGGTTATAGTCCTTAAATATTAATAAAAATAATTGGTACAGTAATTGCTGTATTGACGCTAGACGTC
AAAGATCGGACTCAGGGTGA

Downstream 100 bases:

>100_bases
AGGTCGAATAATTGAAAATTAAAAGATTTTTAGCAAAAGATATGCGATCGGCCTTAGCCCAAGTTAAAGAAACCTTGGGA
TCTGATGCTGTGATCATGTC

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 699; Mature: 699

Protein sequence:

>699_residues
MELKASLGQLKQIKPAHLKGIGTPLLVLAALAMIILPMPAFLLDILFTFNIALALVVLLVAIYSDRPLDFAAFPTVLLVA
TLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGGNYAVGLVVFLILIIINFAVVTKGAGRISEVSARFTLDAMP
GKQMAIDADLNAGLLSQEEARARRAEVTREADFYGAMDGASKFVKGDAVAGILILVINIVGGFIIGIAQHDLSFSSAVEI
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGEMVMGQMFDSPKSLAIASAVMLVMGIVPGMPHLVFLSCAAVSG
AAAYFIKKKKDTDRERALELAKSGPVEPRDIQPKELSWDDVQHVDTIGLEVGYRLIPLVDKGQGGELLGRIKGVRKKLSQ
ELGFLVPAVHIRDNLDLSPNAYRISLMGVSSGEAEIRHDCELAINPGQVYGKLDGIETKDPAFGLDAVWIAPEMREHAQT
LGYTVVDASTVVATHISQLLTNNAAKLLGYEEVQQLLEMLGKHSPKLVDGFIPDVMPLGTVVKVMQNLLNEGVSIRDMKT
IVQTLLEYGTKSSDTEVLTAAVRIALKRMIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGPNIEPSLAERMQKSL
VDATQRQEMVGQPAILLTSGMLRSTLSRFVKHTIPNLRVISYQEVPDEKQIRIVSAVGQ

Sequences:

>Translated_699_residues
MELKASLGQLKQIKPAHLKGIGTPLLVLAALAMIILPMPAFLLDILFTFNIALALVVLLVAIYSDRPLDFAAFPTVLLVA
TLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGGNYAVGLVVFLILIIINFAVVTKGAGRISEVSARFTLDAMP
GKQMAIDADLNAGLLSQEEARARRAEVTREADFYGAMDGASKFVKGDAVAGILILVINIVGGFIIGIAQHDLSFSSAVEI
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGEMVMGQMFDSPKSLAIASAVMLVMGIVPGMPHLVFLSCAAVSG
AAAYFIKKKKDTDRERALELAKSGPVEPRDIQPKELSWDDVQHVDTIGLEVGYRLIPLVDKGQGGELLGRIKGVRKKLSQ
ELGFLVPAVHIRDNLDLSPNAYRISLMGVSSGEAEIRHDCELAINPGQVYGKLDGIETKDPAFGLDAVWIAPEMREHAQT
LGYTVVDASTVVATHISQLLTNNAAKLLGYEEVQQLLEMLGKHSPKLVDGFIPDVMPLGTVVKVMQNLLNEGVSIRDMKT
IVQTLLEYGTKSSDTEVLTAAVRIALKRMIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGPNIEPSLAERMQKSL
VDATQRQEMVGQPAILLTSGMLRSTLSRFVKHTIPNLRVISYQEVPDEKQIRIVSAVGQ
>Mature_699_residues
MELKASLGQLKQIKPAHLKGIGTPLLVLAALAMIILPMPAFLLDILFTFNIALALVVLLVAIYSDRPLDFAAFPTVLLVA
TLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGGNYAVGLVVFLILIIINFAVVTKGAGRISEVSARFTLDAMP
GKQMAIDADLNAGLLSQEEARARRAEVTREADFYGAMDGASKFVKGDAVAGILILVINIVGGFIIGIAQHDLSFSSAVEI
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGEMVMGQMFDSPKSLAIASAVMLVMGIVPGMPHLVFLSCAAVSG
AAAYFIKKKKDTDRERALELAKSGPVEPRDIQPKELSWDDVQHVDTIGLEVGYRLIPLVDKGQGGELLGRIKGVRKKLSQ
ELGFLVPAVHIRDNLDLSPNAYRISLMGVSSGEAEIRHDCELAINPGQVYGKLDGIETKDPAFGLDAVWIAPEMREHAQT
LGYTVVDASTVVATHISQLLTNNAAKLLGYEEVQQLLEMLGKHSPKLVDGFIPDVMPLGTVVKVMQNLLNEGVSIRDMKT
IVQTLLEYGTKSSDTEVLTAAVRIALKRMIVQEISGPELEIPVITLAPELEQMLHQSMQATGGDGPNIEPSLAERMQKSL
VDATQRQEMVGQPAILLTSGMLRSTLSRFVKHTIPNLRVISYQEVPDEKQIRIVSAVGQ

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=695, Percent_Identity=53.0935251798561, Blast_Score=708, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75028; Mature: 75028

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELKASLGQLKQIKPAHLKGIGTPLLVLAALAMIILPMPAFLLDILFTFNIALALVVLLV
CCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AIYSDRPLDFAAFPTVLLVATLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHCCEEECC
NYAVGLVVFLILIIINFAVVTKGAGRISEVSARFTLDAMPGKQMAIDADLNAGLLSQEEA
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCHHHH
RARRAEVTREADFYGAMDGASKFVKGDAVAGILILVINIVGGFIIGIAQHDLSFSSAVEI
HHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGEMVMGQMFDSPKSLAIASAVMLV
HHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
MGIVPGMPHLVFLSCAAVSGAAAYFIKKKKDTDRERALELAKSGPVEPRDIQPKELSWDD
HHHCCCCHHHHHHHHHHHCCHHHHHEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHH
VQHVDTIGLEVGYRLIPLVDKGQGGELLGRIKGVRKKLSQELGFLVPAVHIRDNLDLSPN
HHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
AYRISLMGVSSGEAEIRHDCELAINPGQVYGKLDGIETKDPAFGLDAVWIAPEMREHAQT
CEEEEEEECCCCCCHHCCCCEEEECCCHHEEEECCCCCCCCCCCCCEEEECHHHHHHHHH
LGYTVVDASTVVATHISQLLTNNAAKLLGYEEVQQLLEMLGKHSPKLVDGFIPDVMPLGT
HCEEEECHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHH
VVKVMQNLLNEGVSIRDMKTIVQTLLEYGTKSSDTEVLTAAVRIALKRMIVQEISGPELE
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
IPVITLAPELEQMLHQSMQATGGDGPNIEPSLAERMQKSLVDATQRQEMVGQPAILLTSG
EEEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
MLRSTLSRFVKHTIPNLRVISYQEVPDEKQIRIVSAVGQ
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHEEEEECCCC
>Mature Secondary Structure
MELKASLGQLKQIKPAHLKGIGTPLLVLAALAMIILPMPAFLLDILFTFNIALALVVLLV
CCCHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
AIYSDRPLDFAAFPTVLLVATLLRLALNVASTRVVLLEGHNGGDAAGKVIEAFGSVVIGG
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHHHHCCEEECC
NYAVGLVVFLILIIINFAVVTKGAGRISEVSARFTLDAMPGKQMAIDADLNAGLLSQEEA
CHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEEECCCCCCEEEECCCCCCCCCHHHH
RARRAEVTREADFYGAMDGASKFVKGDAVAGILILVINIVGGFIIGIAQHDLSFSSAVEI
HHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YTLLTIGDGLVAQIPGLLLSIAAALMVTRQNESGDMGEMVMGQMFDSPKSLAIASAVMLV
HHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
MGIVPGMPHLVFLSCAAVSGAAAYFIKKKKDTDRERALELAKSGPVEPRDIQPKELSWDD
HHHCCCCHHHHHHHHHHHCCHHHHHEECCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHH
VQHVDTIGLEVGYRLIPLVDKGQGGELLGRIKGVRKKLSQELGFLVPAVHIRDNLDLSPN
HHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
AYRISLMGVSSGEAEIRHDCELAINPGQVYGKLDGIETKDPAFGLDAVWIAPEMREHAQT
CEEEEEEECCCCCCHHCCCCEEEECCCHHEEEECCCCCCCCCCCCCEEEECHHHHHHHHH
LGYTVVDASTVVATHISQLLTNNAAKLLGYEEVQQLLEMLGKHSPKLVDGFIPDVMPLGT
HCEEEECHHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHH
VVKVMQNLLNEGVSIRDMKTIVQTLLEYGTKSSDTEVLTAAVRIALKRMIVQEISGPELE
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
IPVITLAPELEQMLHQSMQATGGDGPNIEPSLAERMQKSLVDATQRQEMVGQPAILLTSG
EEEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
MLRSTLSRFVKHTIPNLRVISYQEVPDEKQIRIVSAVGQ
HHHHHHHHHHHHCCCCCEEEEECCCCCCHHEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]