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The map label for this gene is engA [H]

Identifier: 157961137

GI number: 157961137

Start: 1593602

End: 1595074

Strand: Direct

Name: engA [H]

Synonym: Spea_1309

Alternate gene names: 157961137

Gene position: 1593602-1595074 (Clockwise)

Preceding gene: 157961136

Following gene: 157961141

Centisome position: 30.8

GC content: 48.47

Gene sequence:

>1473_bases
ATGATTCCTGTTGTGGCCCTAGTTGGGCGACCAAACGTTGGTAAGTCGACCCTTTTTAACCGACTTACCCGTACCAGAGA
TGCGCTTGTCGCTGACTTTCCTGGGCTAACTCGGGATCGTAAATACGGCCGAGCACATCTTGCAGGTTACGAGTTCATCG
TGGTCGATACCGGCGGTATTGATGGCACCGAAGAAGGGATTGAGACTCGCATGGCCGAGCAATCTCTCGCTGCGATTGAA
GAAGCAGATGTGGTGCTATTTTTGACCGACGCTCGCGCTGGCTTAACGGCTGCCGATCTTGCGATTGCTCAACATTTACG
TAGTCGTGAAAAAACCACTTTCGTGGTGGCCAACAAAGTTGACGGTATCGATGCTGATTCAGCTTGTGCTGAATTCTGGT
CACTAGGCCTTGGTGAAGTTTACCAAATGGCTGCGGCTCAAGGCCGTGGTGTAACCAACATGATCGAGTATTCGTTAGCG
CCATACGCAGAAGCGATGGGCATCGTTAAGCAAGAAGACGGTGACGATGACGAAGAAGAGCGCGAATACACCGAAGAGCA
AGCAGAAGCGGAGCAGAAGCGTCTGCAAGACTTGCCTATTAAGCTTGCTATCATCGGTAAGCCTAACGTTGGTAAATCAA
CGCTAACTAACCGTATTTTGGGCGAAGAGCGCGTTGTAGTATATGACGAGCCAGGCACCACTCGTGACAGTATTTACATT
CCTATGGAACGTCAGGGCCGTGAATACGTATTGATTGACACCGCGGGTGTACGTCGTCGTAGTAAGGTTCATGAAACTGT
TGAGAAGTTCTCAGTTATTAAGACCCTTAAAGCGGTTGAAGACAGTAACGTAGTATTACTTGTTATCGATGCCCGTGAAG
GTATTGCCGAGCAAGACCTAGGTCTATTAGGCTTCGTGCTAAACGCTGGCCGTGCATTGGTTATCGCCATCAACAAGTGG
GATGGTATCGACCAAAACATTAAAGACCGTGTGAAGACAGAGCTTGACCGTCGTCTAGGCTTTATCGATTTTGCGCGTAT
TCACTTTATCTCTGCACTTCATGGTACAGGTGTGGGTCACTTGTTCGAGTCAATCGAAGAAGCCTATGACAGTGCGACGC
GCCGCGTAAGTACGTCAATGCTGACTCGTATCATGCAGATGTCACAAGACGATCACCAGCCACCATTGGTTAACGGTCGC
CGCGTTAAGCTTAAATATGCTCACGCCGGTGGTTACAACCCTCCAATCGTGGTTGTACACGGTAACCAGGTTAAGAAGCT
TCCTGATTCTTACAAGCGTTATATGATGAACTACTTCCGTCGTTCATTGAAGGTGATTGGTACACCAATCCAGTTACGTT
TCCAAGAGGGTGGTAATCCGTTTGAGGGTATGAACTCTAAGAAGCTAACTGTGAGCCAAGAGCGTCGTCGTAAGCGTATG
GTTGGCCATATTCGCGATAAGAATAAAGATTAA

Upstream 100 bases:

>100_bases
TCACACTTCCGTAAGCCAAATCGTTAGACATGATAAGGCCCCTGGATGTGTATGCCGGGGGCTTTTTAGTTATTAGAAAA
TGAGTAATAGAGGCAATTAA

Downstream 100 bases:

>100_bases
TTCTTGTTCTTGATTGAAATAAGCAAAATAGCTTAAAAAAGGAACCTCAGGGTTCCTTTTTTGTTGTAGCCGTTCAGATT
ACTTTTCGCTCTGTTGCATC

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAHLAGYEFIVVDTGGIDGTEEGIETRMAEQSLAAIE
EADVVLFLTDARAGLTAADLAIAQHLRSREKTTFVVANKVDGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYSLA
PYAEAMGIVKQEDGDDDEEEREYTEEQAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYI
PMERQGREYVLIDTAGVRRRSKVHETVEKFSVIKTLKAVEDSNVVLLVIDAREGIAEQDLGLLGFVLNAGRALVIAINKW
DGIDQNIKDRVKTELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGR
RVKLKYAHAGGYNPPIVVVHGNQVKKLPDSYKRYMMNYFRRSLKVIGTPIQLRFQEGGNPFEGMNSKKLTVSQERRRKRM
VGHIRDKNKD

Sequences:

>Translated_490_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAHLAGYEFIVVDTGGIDGTEEGIETRMAEQSLAAIE
EADVVLFLTDARAGLTAADLAIAQHLRSREKTTFVVANKVDGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYSLA
PYAEAMGIVKQEDGDDDEEEREYTEEQAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYI
PMERQGREYVLIDTAGVRRRSKVHETVEKFSVIKTLKAVEDSNVVLLVIDAREGIAEQDLGLLGFVLNAGRALVIAINKW
DGIDQNIKDRVKTELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGR
RVKLKYAHAGGYNPPIVVVHGNQVKKLPDSYKRYMMNYFRRSLKVIGTPIQLRFQEGGNPFEGMNSKKLTVSQERRRKRM
VGHIRDKNKD
>Mature_490_residues
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAHLAGYEFIVVDTGGIDGTEEGIETRMAEQSLAAIE
EADVVLFLTDARAGLTAADLAIAQHLRSREKTTFVVANKVDGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYSLA
PYAEAMGIVKQEDGDDDEEEREYTEEQAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYI
PMERQGREYVLIDTAGVRRRSKVHETVEKFSVIKTLKAVEDSNVVLLVIDAREGIAEQDLGLLGFVLNAGRALVIAINKW
DGIDQNIKDRVKTELDRRLGFIDFARIHFISALHGTGVGHLFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGR
RVKLKYAHAGGYNPPIVVVHGNQVKKLPDSYKRYMMNYFRRSLKVIGTPIQLRFQEGGNPFEGMNSKKLTVSQERRRKRM
VGHIRDKNKD

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=494, Percent_Identity=71.6599190283401, Blast_Score=719, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=104, Percent_Identity=36.5384615384615, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=144, Percent_Identity=31.9444444444444, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 54777; Mature: 54777

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAHLAGYEFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCEEEEEEECCCC
DGTEEGIETRMAEQSLAAIEEADVVLFLTDARAGLTAADLAIAQHLRSREKTTFVVANKV
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECC
DGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYSLAPYAEAMGIVKQEDGDDDEEE
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCHHH
REYTEEQAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYI
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEE
PMERQGREYVLIDTAGVRRRSKVHETVEKFSVIKTLKAVEDSNVVLLVIDAREGIAEQDL
EECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHCC
GLLGFVLNAGRALVIAINKWDGIDQNIKDRVKTELDRRLGFIDFARIHFISALHGTGVGH
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHH
LFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGRRVKLKYAHAGGYNPPIVVVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEE
GNQVKKLPDSYKRYMMNYFRRSLKVIGTPIQLRFQEGGNPFEGMNSKKLTVSQERRRKRM
CCCHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEHHHHHHHHHH
VGHIRDKNKD
HHHHHCCCCC
>Mature Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGRAHLAGYEFIVVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEECCEEEEEEECCCC
DGTEEGIETRMAEQSLAAIEEADVVLFLTDARAGLTAADLAIAQHLRSREKTTFVVANKV
CCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEECC
DGIDADSACAEFWSLGLGEVYQMAAAQGRGVTNMIEYSLAPYAEAMGIVKQEDGDDDEEE
CCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCHHH
REYTEEQAEAEQKRLQDLPIKLAIIGKPNVGKSTLTNRILGEERVVVYDEPGTTRDSIYI
HHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCEEEE
PMERQGREYVLIDTAGVRRRSKVHETVEKFSVIKTLKAVEDSNVVLLVIDAREGIAEQDL
EECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHCC
GLLGFVLNAGRALVIAINKWDGIDQNIKDRVKTELDRRLGFIDFARIHFISALHGTGVGH
HHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHH
LFESIEEAYDSATRRVSTSMLTRIMQMSQDDHQPPLVNGRRVKLKYAHAGGYNPPIVVVH
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEECCCCCCCEEEEE
GNQVKKLPDSYKRYMMNYFRRSLKVIGTPIQLRFQEGGNPFEGMNSKKLTVSQERRRKRM
CCCHHHCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCEEHHHHHHHHHH
VGHIRDKNKD
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA