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The map label for this gene is ushA [C]

Identifier: 157961128

GI number: 157961128

Start: 1582695

End: 1584473

Strand: Reverse

Name: ushA [C]

Synonym: Spea_1300

Alternate gene names: 157961128

Gene position: 1584473-1582695 (Counterclockwise)

Preceding gene: 157961129

Following gene: 157961123

Centisome position: 30.62

GC content: 45.76

Gene sequence:

>1779_bases
ATGACAACCACCCTACCTAAATCAGTGGCGACAAAAGCGCAATACAAGTTAAAACTTGCCCACATCAATGACACTCACTC
ACACTTCGATGCAAACCGTATTCAATTTACGATTTGTGAGCAGCAAAAAGAGCTGACTCTCTATAGCCACACAGGTGGTT
ATGCTCGTATCGCTTACCAGCTCAAACAAGCAAGAAACACAGCCAAAAAAGAACGGCAGGAATTTTTATTCTTGCACGGC
GGAGACAGTTTCCAAGGCACGCTTTACTTCAATGAGTTCAAAGGTAAAGCCAACTCAGACCTGTTGAACATGCTCCAGCC
TGATGCCATGGTGCTAGGCAATCATGAAATAGACGCGGGTAACGAGCCAGTACTCGACTTTCTTAATGATATTAAGTTTC
CCCTAATGGCTGGCAACATGGATCTTAGCCAAGAGTGCCTAAATAAAAGTGCGCGCCTAGCTAATCACCGAAACTTACTC
GACTTTAACCCTGAGTCACAAACTGCCAAAGTACTGCTAAAGCCATTAGCTGATAAGCAAATCGCCTGCTTTGGCATCAC
GCTCGACCAAATGAGTGAAATTGCAGGCCCTGATGAAGACACCCATTTTATTAACGCTATCGCCACTACTCGGCGCACGG
TTGCTCAGCTAAAGGCTCAGGGCATTGACCACATTATCGTATTGAGTCACCTAGGGCTGGATCAAGATAAAGTCTTAGCC
AGTGAAGTCGATGGCATTAGCCTCATTGTTGGTGGTCACTCACATACCCTACAAGGTGACTTTAGTGAGCTTGGCTTATC
TAATATGCCCTATGGTGAGCGTATTAACGATACCGCGATAGTACACGCAGGTAAGTATGCCGAAACCTTAGGTATTGCCG
ACATCACTTTTGACTCTAAAGGTAAGGTATTAACGCTCATGGGTGGCAATTACTTCATGTTAGATCAGCAGTTTATCCTG
CAGGCTTCCGATGATGTCAGTCCTCAAGATTATCTAAATGTTCGTCAACAACTACAATCCCATCCACTGATCTTATGGGA
TGGTGAAGATAGCTTGGTGCAGACAAGAATTCAGCAAAAATACCGACCTAGTCTCGATGCGCTAAATAATAAAATCTTGG
GCTTTGTCCCTAAAAGCTTGGTTCATACACGCTTGCCCAGCAAAGCTCTGCCCCACGGCAGTGAAATTGCGCCATGGGTC
AGCCGTAGCATGTATCAGGAAACCAGAGAGCTAGGGGTTGAGGTCGACTTCGCACTGCATAATGCCGGTGGCGTACGTCA
GTCTCTCGATAAAGGTGATGTGAGTTTGGCGGAGATCTTAGGACGCATTTTACCTTTCGACATCCCATTAGTGACCTATG
AGATCCAAGGCCAGTATCTATTTCAGATGCTAGAGTCTGCGATAAATGCGGCAACCAATAACAGTGTGATTGGCACTGGT
GCGGGAAGCTTCCCTTACACCTATGGCTTGAAATACTTTTATGATGGTAAACAGGCTTTAGGACAACGCATCATCAAGCT
TGAAGTCCTCAGTGATGTAGAAGGTACAATGCAGTGGCGAGAAGTCGATGCGAAGGCTCATTATAAAGGGGTCTCCTCTT
CCTATACCGCATCGGGTAAGGAAGGTTATCACCCGATATTGAAAGCAAATTGGCAAAAAGATGTCGATGGCTTGAGTCTG
CCACAAGCTTTCATTCGCTTTATCAGTAAAGCCCAAAGCTTAGATGAAGTGCTCGAACCACAGGTTCACTACACCAGCCA
TAATCTCGCGCCACTGTAA

Upstream 100 bases:

>100_bases
TCAGCCCAGCCTTAAAATCTGCCCTTGCTTAAAAGCAAATTCGGCTTGTTAATAATTAGCCTCGCTGTGCTATACTCCTT
GTTTGGTCCCGAGGAATAAG

Downstream 100 bases:

>100_bases
TTAAATGCAATTGAGTGGGCAAGGGCTGAACTTCAGTCTTGCCCCCACAACAAAGCAGATTATTTTAGGCTAACGGCTTT
ACCATACTGAAGTTGACCAG

Product: 5'-nucleotidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 592; Mature: 591

Protein sequence:

>592_residues
MTTTLPKSVATKAQYKLKLAHINDTHSHFDANRIQFTICEQQKELTLYSHTGGYARIAYQLKQARNTAKKERQEFLFLHG
GDSFQGTLYFNEFKGKANSDLLNMLQPDAMVLGNHEIDAGNEPVLDFLNDIKFPLMAGNMDLSQECLNKSARLANHRNLL
DFNPESQTAKVLLKPLADKQIACFGITLDQMSEIAGPDEDTHFINAIATTRRTVAQLKAQGIDHIIVLSHLGLDQDKVLA
SEVDGISLIVGGHSHTLQGDFSELGLSNMPYGERINDTAIVHAGKYAETLGIADITFDSKGKVLTLMGGNYFMLDQQFIL
QASDDVSPQDYLNVRQQLQSHPLILWDGEDSLVQTRIQQKYRPSLDALNNKILGFVPKSLVHTRLPSKALPHGSEIAPWV
SRSMYQETRELGVEVDFALHNAGGVRQSLDKGDVSLAEILGRILPFDIPLVTYEIQGQYLFQMLESAINAATNNSVIGTG
AGSFPYTYGLKYFYDGKQALGQRIIKLEVLSDVEGTMQWREVDAKAHYKGVSSSYTASGKEGYHPILKANWQKDVDGLSL
PQAFIRFISKAQSLDEVLEPQVHYTSHNLAPL

Sequences:

>Translated_592_residues
MTTTLPKSVATKAQYKLKLAHINDTHSHFDANRIQFTICEQQKELTLYSHTGGYARIAYQLKQARNTAKKERQEFLFLHG
GDSFQGTLYFNEFKGKANSDLLNMLQPDAMVLGNHEIDAGNEPVLDFLNDIKFPLMAGNMDLSQECLNKSARLANHRNLL
DFNPESQTAKVLLKPLADKQIACFGITLDQMSEIAGPDEDTHFINAIATTRRTVAQLKAQGIDHIIVLSHLGLDQDKVLA
SEVDGISLIVGGHSHTLQGDFSELGLSNMPYGERINDTAIVHAGKYAETLGIADITFDSKGKVLTLMGGNYFMLDQQFIL
QASDDVSPQDYLNVRQQLQSHPLILWDGEDSLVQTRIQQKYRPSLDALNNKILGFVPKSLVHTRLPSKALPHGSEIAPWV
SRSMYQETRELGVEVDFALHNAGGVRQSLDKGDVSLAEILGRILPFDIPLVTYEIQGQYLFQMLESAINAATNNSVIGTG
AGSFPYTYGLKYFYDGKQALGQRIIKLEVLSDVEGTMQWREVDAKAHYKGVSSSYTASGKEGYHPILKANWQKDVDGLSL
PQAFIRFISKAQSLDEVLEPQVHYTSHNLAPL
>Mature_591_residues
TTTLPKSVATKAQYKLKLAHINDTHSHFDANRIQFTICEQQKELTLYSHTGGYARIAYQLKQARNTAKKERQEFLFLHGG
DSFQGTLYFNEFKGKANSDLLNMLQPDAMVLGNHEIDAGNEPVLDFLNDIKFPLMAGNMDLSQECLNKSARLANHRNLLD
FNPESQTAKVLLKPLADKQIACFGITLDQMSEIAGPDEDTHFINAIATTRRTVAQLKAQGIDHIIVLSHLGLDQDKVLAS
EVDGISLIVGGHSHTLQGDFSELGLSNMPYGERINDTAIVHAGKYAETLGIADITFDSKGKVLTLMGGNYFMLDQQFILQ
ASDDVSPQDYLNVRQQLQSHPLILWDGEDSLVQTRIQQKYRPSLDALNNKILGFVPKSLVHTRLPSKALPHGSEIAPWVS
RSMYQETRELGVEVDFALHNAGGVRQSLDKGDVSLAEILGRILPFDIPLVTYEIQGQYLFQMLESAINAATNNSVIGTGA
GSFPYTYGLKYFYDGKQALGQRIIKLEVLSDVEGTMQWREVDAKAHYKGVSSSYTASGKEGYHPILKANWQKDVDGLSLP
QAFIRFISKAQSLDEVLEPQVHYTSHNLAPL

Specific function: Degradation Of External Udp-Glucose To Uridine Monophosphate And Glucose-1-Phosphate, Which Can Then Be Used By The Cell. [C]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=589, Percent_Identity=24.2784380305603, Blast_Score=129, Evalue=8e-30,
Organism=Escherichia coli, GI1790658, Length=323, Percent_Identity=24.1486068111455, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28573524, Length=541, Percent_Identity=28.0961182994455, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI19922444, Length=559, Percent_Identity=26.4758497316637, Blast_Score=175, Evalue=9e-44,
Organism=Drosophila melanogaster, GI24641187, Length=557, Percent_Identity=26.7504488330341, Blast_Score=162, Evalue=8e-40,
Organism=Drosophila melanogaster, GI221329836, Length=552, Percent_Identity=27.3550724637681, Blast_Score=160, Evalue=3e-39,
Organism=Drosophila melanogaster, GI19922446, Length=559, Percent_Identity=24.6869409660107, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24654424, Length=559, Percent_Identity=24.6869409660107, Blast_Score=152, Evalue=6e-37,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843
- InterPro:   IPR006420 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 65781; Mature: 65650

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTLPKSVATKAQYKLKLAHINDTHSHFDANRIQFTICEQQKELTLYSHTGGYARIAYQ
CCCCCCHHHHCCCEEEEEEEEECCCHHCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHH
LKQARNTAKKERQEFLFLHGGDSFQGTLYFNEFKGKANSDLLNMLQPDAMVLGNHEIDAG
HHHHHHHHHHHHHEEEEEECCCCCEEEEEEEECCCCCCHHHHHHCCCCEEEECCCCCCCC
NEPVLDFLNDIKFPLMAGNMDLSQECLNKSARLANHRNLLDFNPESQTAKVLLKPLADKQ
CCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCC
IACFGITLDQMSEIAGPDEDTHFINAIATTRRTVAQLKAQGIDHIIVLSHLGLDQDKVLA
EEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
SEVDGISLIVGGHSHTLQGDFSELGLSNMPYGERINDTAIVHAGKYAETLGIADITFDSK
HCCCCEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEECCCHHHHCCCEEEEECCC
GKVLTLMGGNYFMLDQQFILQASDDVSPQDYLNVRQQLQSHPLILWDGEDSLVQTRIQQK
CCEEEEECCCEEEECHHHHEECCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHH
YRPSLDALNNKILGFVPKSLVHTRLPSKALPHGSEIAPWVSRSMYQETRELGVEVDFALH
HCCCHHHHCCCHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEE
NAGGVRQSLDKGDVSLAEILGRILPFDIPLVTYEIQGQYLFQMLESAINAATNNSVIGTG
CCCCHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEECC
AGSFPYTYGLKYFYDGKQALGQRIIKLEVLSDVEGTMQWREVDAKAHYKGVSSSYTASGK
CCCCCHHHCCEEEECCHHHHHHHHEEHHHHHCCHHHHHHHHHCCHHHHCCCCCCCCCCCC
EGYHPILKANWQKDVDGLSLPQAFIRFISKAQSLDEVLEPQVHYTSHNLAPL
CCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCC
>Mature Secondary Structure 
TTTLPKSVATKAQYKLKLAHINDTHSHFDANRIQFTICEQQKELTLYSHTGGYARIAYQ
CCCCCHHHHCCCEEEEEEEEECCCHHCCCCCCEEEEEECCCCCEEEEECCCCHHHHHHH
LKQARNTAKKERQEFLFLHGGDSFQGTLYFNEFKGKANSDLLNMLQPDAMVLGNHEIDAG
HHHHHHHHHHHHHEEEEEECCCCCEEEEEEEECCCCCCHHHHHHCCCCEEEECCCCCCCC
NEPVLDFLNDIKFPLMAGNMDLSQECLNKSARLANHRNLLDFNPESQTAKVLLKPLADKQ
CCHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHCCCCCEECCCCHHHHHHHHHHCCCCC
IACFGITLDQMSEIAGPDEDTHFINAIATTRRTVAQLKAQGIDHIIVLSHLGLDQDKVLA
EEEEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
SEVDGISLIVGGHSHTLQGDFSELGLSNMPYGERINDTAIVHAGKYAETLGIADITFDSK
HCCCCEEEEECCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEECCCHHHHCCCEEEEECCC
GKVLTLMGGNYFMLDQQFILQASDDVSPQDYLNVRQQLQSHPLILWDGEDSLVQTRIQQK
CCEEEEECCCEEEECHHHHEECCCCCCHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHH
YRPSLDALNNKILGFVPKSLVHTRLPSKALPHGSEIAPWVSRSMYQETRELGVEVDFALH
HCCCHHHHCCCHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEE
NAGGVRQSLDKGDVSLAEILGRILPFDIPLVTYEIQGQYLFQMLESAINAATNNSVIGTG
CCCCHHHHCCCCCCHHHHHHHHHCCCCCCEEEEEECHHHHHHHHHHHHHCCCCCCEEECC
AGSFPYTYGLKYFYDGKQALGQRIIKLEVLSDVEGTMQWREVDAKAHYKGVSSSYTASGK
CCCCCHHHCCEEEECCHHHHHHHHEEHHHHHCCHHHHHHHHHCCHHHHCCCCCCCCCCCC
EGYHPILKANWQKDVDGLSLPQAFIRFISKAQSLDEVLEPQVHYTSHNLAPL
CCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]