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The map label for this gene is yiaY [H]

Identifier: 157960980

GI number: 157960980

Start: 1393696

End: 1394844

Strand: Reverse

Name: yiaY [H]

Synonym: Spea_1152

Alternate gene names: 157960980

Gene position: 1394844-1393696 (Counterclockwise)

Preceding gene: 157960981

Following gene: 157960977

Centisome position: 26.96

GC content: 47.87

Gene sequence:

>1149_bases
ATGGCTGCTAAATTTTTTATCCCATCTGTCAATATCTTAGGTCAAGATGCCGTAACTGAAGCCATTGGTGACATCAAGTC
ACTCGGCTTTAAAAATGCACTAATTGTTACTGACAAACCTCTGGTTGAAATTGGTCTGGTCGCTCAAGTCACTGACAAAC
TAGCGAGCAACGACATTCGCTCTGTCGTCTTTGATGGTGTTCAGCCAAACCCAACTGTTGGCAATGTCGAAGCGGGTCTT
GAAATTTTAAACGCAAACAACTGTGACTTTGTTATCTCTTTAGGCGGCGGCTCACCTCATGACTGCGCTAAAGGCATCGC
ACTGGTTGCCACCAACGGCGGTAGTATCAAAGATTACGAAGGCTTAGATGTCTCTATCAAGCCTCAGCTGCCACTCGTTG
CCATTAACACCACTGCGGGCACCGCGAGTGAAATGACACGTTTCTGTATCATTACCGATGAAGCTCGCCATATTAAGATG
GCCATTGTCGACAAGAACACCACGCCGATCTTATCAGTTAATGATCCTGAATTAATGTTGCTTAAGCCAGCAGGCCTGAC
TGCTGCAACGGGTATGGATGCATTGACTCACGCCATCGAAGCCTATGTGTCTATCGCGGCAAATCCGATTACCGATGCCT
GTGCAATTAAAGCGATAGAGCTTATTCAAGGTAACTTGGTAGAAGCCGTTGAAAATGGCCAAAGTATCGAGGCGCGCGAT
CAGATGGCTTACGCCCAGTTCCTTGCAGGTATGGCGTTTAACAACGCAAGCCTTGGATATGTCCACGCTATGGCCCACCA
GCTAGGTGGCTTCTACGACCTACCTCATGGCGTATGTAACGCATTATTGTTACCACACGTTCAAGCTTACAACGCGCAGG
TTGTGCCGGGGCGTCTAAAGGATGTAGCTAAAGCCATGGGGGTCGATGTCGCAGCCATGACTGATGAGCAAGGTGCCGAA
GCGGCGATTACCGCAATTAAAGCGCTATCTGTCGCGGTTAACATCCCAGAAAACCTCACTAAGCTAGGTGTTAAAGCGGA
AGATATTCCGACACTTGCTAATAACGCGCTAAAAGATGCTTGTGGTTTCACTAACCCTAAGCAGGCAACTCATGAAGAGA
TCTGCCAAATCTTCACTAACGCACTGTGA

Upstream 100 bases:

>100_bases
GATTATTAGAGGAAGATCACACCTTTATTTCATTGCTGTTGGTACTTTAATTACCAGAAAAGATAACAACTTTGAACATT
AAGCATAATAGGTGATTCTT

Downstream 100 bases:

>100_bases
TCCAGCTTGGCTCCAATTTGAGTCCAGTGCATCAGTTAACAGAGTAATAGCTGAAACTAGCAAGCGACTTATGTTTAAAA
AAGTGAGCTTGCTATCTTTC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 382; Mature: 381

Protein sequence:

>382_residues
MAAKFFIPSVNILGQDAVTEAIGDIKSLGFKNALIVTDKPLVEIGLVAQVTDKLASNDIRSVVFDGVQPNPTVGNVEAGL
EILNANNCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDVSIKPQLPLVAINTTAGTASEMTRFCIITDEARHIKM
AIVDKNTTPILSVNDPELMLLKPAGLTAATGMDALTHAIEAYVSIAANPITDACAIKAIELIQGNLVEAVENGQSIEARD
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQAYNAQVVPGRLKDVAKAMGVDVAAMTDEQGAE
AAITAIKALSVAVNIPENLTKLGVKAEDIPTLANNALKDACGFTNPKQATHEEICQIFTNAL

Sequences:

>Translated_382_residues
MAAKFFIPSVNILGQDAVTEAIGDIKSLGFKNALIVTDKPLVEIGLVAQVTDKLASNDIRSVVFDGVQPNPTVGNVEAGL
EILNANNCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDVSIKPQLPLVAINTTAGTASEMTRFCIITDEARHIKM
AIVDKNTTPILSVNDPELMLLKPAGLTAATGMDALTHAIEAYVSIAANPITDACAIKAIELIQGNLVEAVENGQSIEARD
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQAYNAQVVPGRLKDVAKAMGVDVAAMTDEQGAE
AAITAIKALSVAVNIPENLTKLGVKAEDIPTLANNALKDACGFTNPKQATHEEICQIFTNAL
>Mature_381_residues
AAKFFIPSVNILGQDAVTEAIGDIKSLGFKNALIVTDKPLVEIGLVAQVTDKLASNDIRSVVFDGVQPNPTVGNVEAGLE
ILNANNCDFVISLGGGSPHDCAKGIALVATNGGSIKDYEGLDVSIKPQLPLVAINTTAGTASEMTRFCIITDEARHIKMA
IVDKNTTPILSVNDPELMLLKPAGLTAATGMDALTHAIEAYVSIAANPITDACAIKAIELIQGNLVEAVENGQSIEARDQ
MAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQAYNAQVVPGRLKDVAKAMGVDVAAMTDEQGAEA
AITAIKALSVAVNIPENLTKLGVKAEDIPTLANNALKDACGFTNPKQATHEEICQIFTNAL

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=413, Percent_Identity=28.5714285714286, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI48994951, Length=381, Percent_Identity=67.4540682414698, Blast_Score=530, Evalue=1e-152,
Organism=Escherichia coli, GI1789163, Length=384, Percent_Identity=43.75, Blast_Score=319, Evalue=1e-88,
Organism=Escherichia coli, GI87082107, Length=377, Percent_Identity=35.2785145888594, Blast_Score=215, Evalue=4e-57,
Organism=Escherichia coli, GI1787493, Length=391, Percent_Identity=31.9693094629156, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1789386, Length=321, Percent_Identity=24.9221183800623, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17537053, Length=406, Percent_Identity=25.3694581280788, Blast_Score=113, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321181, Length=379, Percent_Identity=54.353562005277, Blast_Score=406, Evalue=1e-114,
Organism=Drosophila melanogaster, GI24657991, Length=410, Percent_Identity=27.3170731707317, Blast_Score=145, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 39967; Mature: 39836

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKFFIPSVNILGQDAVTEAIGDIKSLGFKNALIVTDKPLVEIGLVAQVTDKLASNDIR
CCCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCHHH
SVVFDGVQPNPTVGNVEAGLEILNANNCDFVISLGGGSPHDCAKGIALVATNGGSIKDYE
HHHCCCCCCCCCCCCHHHCEEEEECCCCEEEEECCCCCCCHHHCCEEEEEECCCCCCCCC
GLDVSIKPQLPLVAINTTAGTASEMTRFCIITDEARHIKMAIVDKNTTPILSVNDPELML
CCEEEECCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCEEEEECCCCEEE
LKPAGLTAATGMDALTHAIEAYVSIAANPITDACAIKAIELIQGNLVEAVENGQSIEARD
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCHHH
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQAYNAQVVPGRLK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHCCCEECCHHHH
DVAKAMGVDVAAMTDEQGAEAAITAIKALSVAVNIPENLTKLGVKAEDIPTLANNALKDA
HHHHHHCCCEEEECCCCCHHHHHHHHHHHHEEEECCHHHHHHCCCCCCCCHHHHHHHHHH
CGFTNPKQATHEEICQIFTNAL
CCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAKFFIPSVNILGQDAVTEAIGDIKSLGFKNALIVTDKPLVEIGLVAQVTDKLASNDIR
CCEEECCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCHHH
SVVFDGVQPNPTVGNVEAGLEILNANNCDFVISLGGGSPHDCAKGIALVATNGGSIKDYE
HHHCCCCCCCCCCCCHHHCEEEEECCCCEEEEECCCCCCCHHHCCEEEEEECCCCCCCCC
GLDVSIKPQLPLVAINTTAGTASEMTRFCIITDEARHIKMAIVDKNTTPILSVNDPELML
CCEEEECCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEEECCCCEEEEECCCCEEE
LKPAGLTAATGMDALTHAIEAYVSIAANPITDACAIKAIELIQGNLVEAVENGQSIEARD
ECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCHHH
QMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNALLLPHVQAYNAQVVPGRLK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHCCCEECCHHHH
DVAKAMGVDVAAMTDEQGAEAAITAIKALSVAVNIPENLTKLGVKAEDIPTLANNALKDA
HHHHHHCCCEEEECCCCCHHHHHHHHHHHHEEEECCHHHHHHCCCCCCCCHHHHHHHHHH
CGFTNPKQATHEEICQIFTNAL
CCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]