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The map label for this gene is rbsK [H]

Identifier: 157960347

GI number: 157960347

Start: 632466

End: 633389

Strand: Direct

Name: rbsK [H]

Synonym: Spea_0518

Alternate gene names: 157960347

Gene position: 632466-633389 (Clockwise)

Preceding gene: 157960346

Following gene: 157960348

Centisome position: 12.22

GC content: 48.05

Gene sequence:

>924_bases
ATGAAAATGTCTCAGTTAATCGTTTTAGGCAGTGTGAATGCCGACCATGTTCTTCAAGTGCCTTCTTTCCCACGTCCAGG
CGAAACCCTGCATGGCCATAACTACCAAGTGATCCCTGGTGGTAAAGGGGCTAATCAAGCGGTAGCTGCTGCTCGCCTTG
GTGGCGATATTGGTTTTATCGCTTGCGTAGGTGATGATAGCTTTGGTCAAAATATTCGCCAGACTTTTACAAATGATGGC
ATGGATATTTCAGCAGTACACATGATTGAGAATACCCCAACGGGTATTGCGATGATCCAGGTGAGTGATTGCGGTGAAAA
CAGCATCTGTATCGCCGCTGAGGCAAATAATGCATTAACAGCTGAGATTGTTGAGCAGCATTCGGCAATGATTGAGCAAG
CCGAATATCTATTGATGCAACTAGAAACACCATTAGCGGGCATTGAACTGGCGGCGAGCATTGCTAAAGTGCATGGCACT
CAGGTGGTATTAAACCCAGCGCCTGCGCGTAGCCTACCTGATGCACTCTTGGCTATGGTTGATATCATTACCCCTAACGA
GACTGAAGCCGAAGTGCTAACAGGCGTAGCCGTGACTGATGCCGATAGCGCAGCTAAAGCCGCTCAAGTGCTGCACGACA
AAGGCATAGCGACAGTGATGATCACTCTAGGCGCAAAAGGTGTGTACTTAAGTGAGCAAGACACGGGTAAAATTATCCCA
GGATTTAAGGTAAAAGCCACCGATACCACTGCTGCAGGGGACACCTTTAACGGCGCATTTGTGACTGGATTACTCGAAGG
TAAAGCTATCGAAAATGCAATCGTGTTTGCCCATGGCGCAGCGGCTATTTCGGTAACCCGTTTTGGTGCACAAACCTCAA
TTCCATCACGAGATGAAGTTGAGCAGTTTATTGCGGCGCAGTAA

Upstream 100 bases:

>100_bases
CTAGTATGCACGTCAATTGAATTGTCATCATTGGCGTATTTTCCCTCTGAGCCCAACATCATTGCGAGTTCGGTTATTGC
TACAGAGGTCATCAAGGAAA

Downstream 100 bases:

>100_bases
CTTATCAAGTGACTCTTTTTTTGAAGCTTTCAAATAAAGAGTCATCAATTAAATCGGCATGAAATCGTCATTTATAACGA
AAGTAATAGCGAAAGTAATA

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MKMSQLIVLGSVNADHVLQVPSFPRPGETLHGHNYQVIPGGKGANQAVAAARLGGDIGFIACVGDDSFGQNIRQTFTNDG
MDISAVHMIENTPTGIAMIQVSDCGENSICIAAEANNALTAEIVEQHSAMIEQAEYLLMQLETPLAGIELAASIAKVHGT
QVVLNPAPARSLPDALLAMVDIITPNETEAEVLTGVAVTDADSAAKAAQVLHDKGIATVMITLGAKGVYLSEQDTGKIIP
GFKVKATDTTAAGDTFNGAFVTGLLEGKAIENAIVFAHGAAAISVTRFGAQTSIPSRDEVEQFIAAQ

Sequences:

>Translated_307_residues
MKMSQLIVLGSVNADHVLQVPSFPRPGETLHGHNYQVIPGGKGANQAVAAARLGGDIGFIACVGDDSFGQNIRQTFTNDG
MDISAVHMIENTPTGIAMIQVSDCGENSICIAAEANNALTAEIVEQHSAMIEQAEYLLMQLETPLAGIELAASIAKVHGT
QVVLNPAPARSLPDALLAMVDIITPNETEAEVLTGVAVTDADSAAKAAQVLHDKGIATVMITLGAKGVYLSEQDTGKIIP
GFKVKATDTTAAGDTFNGAFVTGLLEGKAIENAIVFAHGAAAISVTRFGAQTSIPSRDEVEQFIAAQ
>Mature_307_residues
MKMSQLIVLGSVNADHVLQVPSFPRPGETLHGHNYQVIPGGKGANQAVAAARLGGDIGFIACVGDDSFGQNIRQTFTNDG
MDISAVHMIENTPTGIAMIQVSDCGENSICIAAEANNALTAEIVEQHSAMIEQAEYLLMQLETPLAGIELAASIAKVHGT
QVVLNPAPARSLPDALLAMVDIITPNETEAEVLTGVAVTDADSAAKAAQVLHDKGIATVMITLGAKGVYLSEQDTGKIIP
GFKVKATDTTAAGDTFNGAFVTGLLEGKAIENAIVFAHGAAAISVTRFGAQTSIPSRDEVEQFIAAQ

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=297, Percent_Identity=38.3838383838384, Blast_Score=170, Evalue=1e-42,
Organism=Escherichia coli, GI1790193, Length=302, Percent_Identity=58.6092715231788, Blast_Score=325, Evalue=2e-90,
Organism=Escherichia coli, GI87081971, Length=300, Percent_Identity=27.3333333333333, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1788491, Length=258, Percent_Identity=25.1937984496124, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI87082343, Length=303, Percent_Identity=28.7128712871287, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788484, Length=281, Percent_Identity=22.4199288256228, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788417, Length=306, Percent_Identity=23.5294117647059, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=301, Percent_Identity=40.8637873754153, Blast_Score=197, Evalue=5e-51,
Organism=Caenorhabditis elegans, GI25147470, Length=293, Percent_Identity=25.938566552901, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319884, Length=333, Percent_Identity=28.5285285285285, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI20128807, Length=307, Percent_Identity=34.8534201954397, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24583886, Length=305, Percent_Identity=34.0983606557377, Blast_Score=141, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 31845; Mature: 31845

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKMSQLIVLGSVNADHVLQVPSFPRPGETLHGHNYQVIPGGKGANQAVAAARLGGDIGFI
CCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCEEEE
ACVGDDSFGQNIRQTFTNDGMDISAVHMIENTPTGIAMIQVSDCGENSICIAAEANNALT
EEECCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCCHH
AEIVEQHSAMIEQAEYLLMQLETPLAGIELAASIAKVHGTQVVLNPAPARSLPDALLAMV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHH
DIITPNETEAEVLTGVAVTDADSAAKAAQVLHDKGIATVMITLGAKGVYLSEQDTGKIIP
HEECCCCCCHHHEEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCC
GFKVKATDTTAAGDTFNGAFVTGLLEGKAIENAIVFAHGAAAISVTRFGAQTSIPSRDEV
CEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCEEEEEEECCCCCCCCCHHHH
EQFIAAQ
HHHHCCC
>Mature Secondary Structure
MKMSQLIVLGSVNADHVLQVPSFPRPGETLHGHNYQVIPGGKGANQAVAAARLGGDIGFI
CCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHCCCCEEEE
ACVGDDSFGQNIRQTFTNDGMDISAVHMIENTPTGIAMIQVSDCGENSICIAAEANNALT
EEECCCHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCCCEEEEEECCCCHH
AEIVEQHSAMIEQAEYLLMQLETPLAGIELAASIAKVHGTQVVLNPAPARSLPDALLAMV
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCEEEECCCCCCCHHHHHHHHH
DIITPNETEAEVLTGVAVTDADSAAKAAQVLHDKGIATVMITLGAKGVYLSEQDTGKIIP
HEECCCCCCHHHEEEEEEECCCHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCCCCCCC
GFKVKATDTTAAGDTFNGAFVTGLLEGKAIENAIVFAHGAAAISVTRFGAQTSIPSRDEV
CEEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCEEEEEEECCCCCCCCCHHHH
EQFIAAQ
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]