Click here to switch to the map view.

The map label for this gene is sspA [C]

Identifier: 157960331

GI number: 157960331

Start: 615214

End: 615927

Strand: Direct

Name: sspA [C]

Synonym: Spea_0502

Alternate gene names: 157960331

Gene position: 615214-615927 (Clockwise)

Preceding gene: 157960330

Following gene: 157960332

Centisome position: 11.89

GC content: 41.46

Gene sequence:

>714_bases
ATGTTGAAAATAGTAAGTTATGTCATATGTCCATTCGTGCAACGCATTACTGGTCTACTCGAGGCTAAGGGAGTGTCTTA
TCAAATTGAATACATTAGCCTTAAGGATAAGCCACAATGGTTTCTCGATATTGCACCTAACGGTCAAGTTCCTGTTCTGA
TCACAGAAGATAACATTGCACTGTCAGAGTCAGATGCGATCGCTGAATACCTAGATGATGAATATCCTTTGCTAAGACCT
GAAGTTAATAAATCTGCTTGCCGTGCAAGACAGAGAGCCTGGGTGTATCAAGCAAGCAAACTTTATCTTAAACAATGTAG
TCATATGCAAAGTCCTACTCAGCAAGTCTTTGAGGAGCGACAAGAATACCTGCAAAATCAGTTTGCCAAGGTTGAGTCTT
TTCTTAAAGACCACACCGATAGCCAATATTTCTGTGCCAACGTGATAGGTAACATCGATATTGCTTGGCTGCCTTTGTTT
CACCGGGCGGCATTAGTGCAAAAGCACACTGGAATGAGATTATTTGAAAACTTTCCTCTGCTTCAGACATGGGCCGATAA
TATCATGGCGACAGGCCTTGCTGAGAAAACGGTTCATGACAGTTTTGAAGCGCGTTTTGTTAATTTCTACCTAAGTGATA
AGACATATCTTGGTAGCGGAAACAAACGCAACAACCAGAGCTGCAATACTTCATCGACTTCTTGTTGTGCTTAA

Upstream 100 bases:

>100_bases
TGAACAAAAATCTGCGTCATGCAAAAAATGCTAAATAACTTCGTCCTTTCTATGCCTGCATCGTCTTATAGGTAAATTCA
TTAACGATATAGGTTTAAAA

Downstream 100 bases:

>100_bases
TCTCACTTATTAAGAAAGGCTGAGAAGGCTATGGGACCAAAATTTGGCCCCATAGCTTGGGTATTGACGCTGACTGTACC
GTTATCTTCTATCCGCTACT

Product: glutathione S-transferase domain-containing protein

Products: HX; R-S-glutathione

Alternate protein names: Glutathione S-Transferase Domain-Containing Protein; Glutathione S-Transferase Protein; Glutathione S-Transferase Domain Protein; Glutathione S-Transferase Domain; Glutathione-S-Transferase; Glutathione S-Transferase-Like Protein; Glutathione-S-Transferase Protein; Glutathione S-Transferase-Like; Glutathione S-Transferase Family Protein; Glutathione S Transferase; Stringent Starvation Protein A; Glucose-Inhibited Division Protein A Subfamily Protein

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MLKIVSYVICPFVQRITGLLEAKGVSYQIEYISLKDKPQWFLDIAPNGQVPVLITEDNIALSESDAIAEYLDDEYPLLRP
EVNKSACRARQRAWVYQASKLYLKQCSHMQSPTQQVFEERQEYLQNQFAKVESFLKDHTDSQYFCANVIGNIDIAWLPLF
HRAALVQKHTGMRLFENFPLLQTWADNIMATGLAEKTVHDSFEARFVNFYLSDKTYLGSGNKRNNQSCNTSSTSCCA

Sequences:

>Translated_237_residues
MLKIVSYVICPFVQRITGLLEAKGVSYQIEYISLKDKPQWFLDIAPNGQVPVLITEDNIALSESDAIAEYLDDEYPLLRP
EVNKSACRARQRAWVYQASKLYLKQCSHMQSPTQQVFEERQEYLQNQFAKVESFLKDHTDSQYFCANVIGNIDIAWLPLF
HRAALVQKHTGMRLFENFPLLQTWADNIMATGLAEKTVHDSFEARFVNFYLSDKTYLGSGNKRNNQSCNTSSTSCCA
>Mature_237_residues
MLKIVSYVICPFVQRITGLLEAKGVSYQIEYISLKDKPQWFLDIAPNGQVPVLITEDNIALSESDAIAEYLDDEYPLLRP
EVNKSACRARQRAWVYQASKLYLKQCSHMQSPTQQVFEERQEYLQNQFAKVESFLKDHTDSQYFCANVIGNIDIAWLPLF
HRAALVQKHTGMRLFENFPLLQTWADNIMATGLAEKTVHDSFEARFVNFYLSDKTYLGSGNKRNNQSCNTSSTSCCA

Specific function: Forms An Equimolar Complex With The RNA Polymerase Holoenzyme (Rnap) But Not With The Core Enzyme. It Is Synthesized Predominantly When Cells Are Exposed To Amino Acid Starvation, At Which Time It Accounts For Over 50% Of The Total Protein Synthesized. It

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4758484, Length=164, Percent_Identity=32.3170731707317, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI300360534, Length=157, Percent_Identity=32.484076433121, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI38016131, Length=219, Percent_Identity=24.6575342465753, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI300360532, Length=90, Percent_Identity=38.8888888888889, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355779, Length=215, Percent_Identity=27.906976744186, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355775, Length=94, Percent_Identity=41.4893617021277, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24660979, Length=210, Percent_Identity=26.1904761904762, Blast_Score=68, Evalue=7e-12,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1982 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18

Molecular weight: Translated: 27157; Mature: 27157

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIVSYVICPFVQRITGLLEAKGVSYQIEYISLKDKPQWFLDIAPNGQVPVLITEDNIA
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEECCCCCEEEEEECCCCE
LSESDAIAEYLDDEYPLLRPEVNKSACRARQRAWVYQASKLYLKQCSHMQSPTQQVFEER
ECCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QEYLQNQFAKVESFLKDHTDSQYFCANVIGNIDIAWLPLFHRAALVQKHTGMRLFENFPL
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCH
LQTWADNIMATGLAEKTVHDSFEARFVNFYLSDKTYLGSGNKRNNQSCNTSSTSCCA
HHHHHHHHHHHCHHHHHHHHHHHHEEEEEEECCCEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLKIVSYVICPFVQRITGLLEAKGVSYQIEYISLKDKPQWFLDIAPNGQVPVLITEDNIA
CHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCEEEEECCCCCEEEEEECCCCE
LSESDAIAEYLDDEYPLLRPEVNKSACRARQRAWVYQASKLYLKQCSHMQSPTQQVFEER
ECCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QEYLQNQFAKVESFLKDHTDSQYFCANVIGNIDIAWLPLFHRAALVQKHTGMRLFENFPL
HHHHHHHHHHHHHHHHHCCCCCEEHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCH
LQTWADNIMATGLAEKTVHDSFEARFVNFYLSDKTYLGSGNKRNNQSCNTSSTSCCA
HHHHHHHHHHHCHHHHHHHHHHHHEEEEEEECCCEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; glutathione

Specific reaction: RX + glutathione = HX + R-S-glutathione

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA