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The map label for this gene is frdC [H]

Identifier: 157960222

GI number: 157960222

Start: 474746

End: 475420

Strand: Direct

Name: frdC [H]

Synonym: Spea_0393

Alternate gene names: 157960222

Gene position: 474746-475420 (Clockwise)

Preceding gene: 157960221

Following gene: 157960223

Centisome position: 9.17

GC content: 47.41

Gene sequence:

>675_bases
ATGAATAAAATAACAGATCGCGGTAATTGGAGTGGTTGGTTGGATCTGAGCCAGAGTATCTCTGGCGCAGTATTGGCAAT
ATTTTTATGGACACACCTAATATTGGTCTCCTCTATCTTGCTGGGGGAAGAGGCAATGACTTGGGTTGCCAAGACCATGG
AGCTGAGTTTCTTGAGTGCCGATGGTCATGGTTACCCTTGGGTCGTGTCGATTATTGCGCTGTTAATTGCTGCAATAGTG
TTGATACATGTATTGGTGGCCATCCATAAGTTGCCGCTTAGTTTACGTCAGCAGAAGGCGTTAAAGCTGCAGCTTATCTC
GATTAATCACGGTGATACAAGATTATGGGTATGGCAGGCGGCCACTGGGGTGGTGATCTTATTATTACTGCCCGTACATT
TGTGGTTAATAGGAGCTGCGCCTGAAACCATTGGCCCCCATGGCAGTGCCGACAGAATTTGGCAGCAGGGAGTATGGTTG
CTGTATCTGCCATTGTTACTCTGCGTTGAGCTCCATGCCGCGATTGGTGTATACCGTCTAGCGGTGAAATGGGGCGCGGT
GAGAGAGCTTAATACCCGCAAAAGACTTAAAAAAATAAAGACTATCATCAGCGTGGTTTTCATTGTTATAGGCTTGGCGT
CCTTATTGGCGTTCCTCCCCTATGCCAATGGGTAG

Upstream 100 bases:

>100_bases
CGCGTATTTGTTGATCTATCTCACGGTTAAATGCCTGTTACTGGGTGACATTGTAACTAAACAGTAACAAGTTAGGCATT
AACCAAAGATAGGGCAGCGA

Downstream 100 bases:

>100_bases
CTGCTGGTGAGAACAAGAACATAAACTGACTCTGCACCCTACGTTAAGGAGCACGTGTGAAACTGATATATACCGATTCG
TTAGTGATCGGCGCTGGACT

Product: fumarate reductase respiratory complex transmembrane subunit

Products: fumarate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MNKITDRGNWSGWLDLSQSISGAVLAIFLWTHLILVSSILLGEEAMTWVAKTMELSFLSADGHGYPWVVSIIALLIAAIV
LIHVLVAIHKLPLSLRQQKALKLQLISINHGDTRLWVWQAATGVVILLLLPVHLWLIGAAPETIGPHGSADRIWQQGVWL
LYLPLLLCVELHAAIGVYRLAVKWGAVRELNTRKRLKKIKTIISVVFIVIGLASLLAFLPYANG

Sequences:

>Translated_224_residues
MNKITDRGNWSGWLDLSQSISGAVLAIFLWTHLILVSSILLGEEAMTWVAKTMELSFLSADGHGYPWVVSIIALLIAAIV
LIHVLVAIHKLPLSLRQQKALKLQLISINHGDTRLWVWQAATGVVILLLLPVHLWLIGAAPETIGPHGSADRIWQQGVWL
LYLPLLLCVELHAAIGVYRLAVKWGAVRELNTRKRLKKIKTIISVVFIVIGLASLLAFLPYANG
>Mature_224_residues
MNKITDRGNWSGWLDLSQSISGAVLAIFLWTHLILVSSILLGEEAMTWVAKTMELSFLSADGHGYPWVVSIIALLIAAIV
LIHVLVAIHKLPLSLRQQKALKLQLISINHGDTRLWVWQAATGVVILLLLPVHLWLIGAAPETIGPHGSADRIWQQGVWL
LYLPLLLCVELHAAIGVYRLAVKWGAVRELNTRKRLKKIKTIISVVFIVIGLASLLAFLPYANG

Specific function: Di-heme cytochrome of the fumarate reductase complex [H]

COG id: COG2009

COG function: function code C; Succinate dehydrogenase/fumarate reductase, cytochrome b subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004224
- InterPro:   IPR000701 [H]

Pfam domain/function: PF01127 Sdh_cyt [H]

EC number: 1.3.99.1

Molecular weight: Translated: 24761; Mature: 24761

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKITDRGNWSGWLDLSQSISGAVLAIFLWTHLILVSSILLGEEAMTWVAKTMELSFLSA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
DGHGYPWVVSIIALLIAAIVLIHVLVAIHKLPLSLRQQKALKLQLISINHGDTRLWVWQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEEEEECCCCCEEEEEEH
ATGVVILLLLPVHLWLIGAAPETIGPHGSADRIWQQGVWLLYLPLLLCVELHAAIGVYRL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
AVKWGAVRELNTRKRLKKIKTIISVVFIVIGLASLLAFLPYANG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKITDRGNWSGWLDLSQSISGAVLAIFLWTHLILVSSILLGEEAMTWVAKTMELSFLSA
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEC
DGHGYPWVVSIIALLIAAIVLIHVLVAIHKLPLSLRQQKALKLQLISINHGDTRLWVWQA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEEEEEECCCCCEEEEEEH
ATGVVILLLLPVHLWLIGAAPETIGPHGSADRIWQQGVWLLYLPLLLCVELHAAIGVYRL
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
AVKWGAVRELNTRKRLKKIKTIISVVFIVIGLASLLAFLPYANG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: succinate; acceptor

Specific reaction: succinate + acceptor = fumarate + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]