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The map label for this gene is xerC [H]

Identifier: 157960209

GI number: 157960209

Start: 459448

End: 460362

Strand: Direct

Name: xerC [H]

Synonym: Spea_0380

Alternate gene names: 157960209

Gene position: 459448-460362 (Clockwise)

Preceding gene: 157960208

Following gene: 157960210

Centisome position: 8.88

GC content: 48.09

Gene sequence:

>915_bases
ATGGCTGACGAAGCGTTATCGAGTAATGTGCGTTGGTTGACTGATTTTGAGCGCTACCTGCGCACCGAGCGTCAAGTCTC
TGCTTATACGGTGCGTAATTATCTATTCGAGTTGAAACGCGTCGAGAAACTATTTAGCGAAACGGACTCTTGGCTGTCTC
TGCAGCATGAGTCTTTGCAAGCTATGCTGGCCAAATTACACCGCAAAGGCCTCAGCCCGCGCTCACTGTCGCTGACACTT
TCCTCCTTAAAACAGTTCTATGAGTTTTTGCTTAGAGAGCAACAGATTAAGGTTAATCCAGCTATTAGTCTGACTGCGCC
TAAGCAGGGCAAGCCCCTGCCTAAGAATATGGATGTTGACTCTGTATCGCATCTGCTAGATCTCGATGGCGATGACCCTC
TAAGTCTGCGTGATAAAGCGATTATGGAGCTGTTTTACTCTTCAGGACTGCGACTTGCAGAGCTTGCGGCGCTGAATGTC
GGCGATATTCAATTCTCTCAAGCACAGGTCAAAGTCTTAGGTAAAGGCAGTAAAGAGCGAATAGTGCCTATCGGAAAATT
AGCGTTAACGGCGATAAATCAATGGTTGGATATCAAACGCGATATTGCTTGTGAAGATGACGCCTTGTTTGTTACCGCCA
AAGGTAAACGCTTAGCACACAGAAGTATTCAGGCGCGTCTTGCAAAATGGGGTCAAGAGCAGGCTATAGGCATAAAGGTA
CACCCGCATAAGCTACGTCACTCCTTTGCGACCCATATGCTCGAGTCCAGTGCCGATCTTCGCGCGGTGCAAGAGCTTTT
GGGCCATGCCAATCTGTCTACCACTCAGGTATATACCAGCCTAGACTTCCAACATCTTGCCAAAGTCTATGACAATGCAC
ATCCGCGAGCGAAGAAGCGAGGCGATAAAGCATGA

Upstream 100 bases:

>100_bases
AGATCCCATGCACTTTCATCCAGAGATGGACTACCTTCTTTTGTCACAACTCAAGCAGCTGCTCGATCATCAACTGACAA
AAATCTAATAGCGAGGCTCT

Downstream 100 bases:

>100_bases
AGATCTATATTCGACCACAAGCTTTTGAGGCCATTAGTTTCGACTTGGACGATACCTTATATGATAATCGGCCCATCATT
CGAAGAGCAGAAGCCGAGAT

Product: tyrosine recombinase XerC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MADEALSSNVRWLTDFERYLRTERQVSAYTVRNYLFELKRVEKLFSETDSWLSLQHESLQAMLAKLHRKGLSPRSLSLTL
SSLKQFYEFLLREQQIKVNPAISLTAPKQGKPLPKNMDVDSVSHLLDLDGDDPLSLRDKAIMELFYSSGLRLAELAALNV
GDIQFSQAQVKVLGKGSKERIVPIGKLALTAINQWLDIKRDIACEDDALFVTAKGKRLAHRSIQARLAKWGQEQAIGIKV
HPHKLRHSFATHMLESSADLRAVQELLGHANLSTTQVYTSLDFQHLAKVYDNAHPRAKKRGDKA

Sequences:

>Translated_304_residues
MADEALSSNVRWLTDFERYLRTERQVSAYTVRNYLFELKRVEKLFSETDSWLSLQHESLQAMLAKLHRKGLSPRSLSLTL
SSLKQFYEFLLREQQIKVNPAISLTAPKQGKPLPKNMDVDSVSHLLDLDGDDPLSLRDKAIMELFYSSGLRLAELAALNV
GDIQFSQAQVKVLGKGSKERIVPIGKLALTAINQWLDIKRDIACEDDALFVTAKGKRLAHRSIQARLAKWGQEQAIGIKV
HPHKLRHSFATHMLESSADLRAVQELLGHANLSTTQVYTSLDFQHLAKVYDNAHPRAKKRGDKA
>Mature_303_residues
ADEALSSNVRWLTDFERYLRTERQVSAYTVRNYLFELKRVEKLFSETDSWLSLQHESLQAMLAKLHRKGLSPRSLSLTLS
SLKQFYEFLLREQQIKVNPAISLTAPKQGKPLPKNMDVDSVSHLLDLDGDDPLSLRDKAIMELFYSSGLRLAELAALNVG
DIQFSQAQVKVLGKGSKERIVPIGKLALTAINQWLDIKRDIACEDDALFVTAKGKRLAHRSIQARLAKWGQEQAIGIKVH
PHKLRHSFATHMLESSADLRAVQELLGHANLSTTQVYTSLDFQHLAKVYDNAHPRAKKRGDKA

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4973

COG function: function code L; Site-specific recombinase XerC

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790244, Length=291, Percent_Identity=51.5463917525773, Blast_Score=305, Evalue=3e-84,
Organism=Escherichia coli, GI1789261, Length=281, Percent_Identity=35.9430604982206, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1790768, Length=158, Percent_Identity=26.5822784810127, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790767, Length=180, Percent_Identity=25, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011931 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 34379; Mature: 34248

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADEALSSNVRWLTDFERYLRTERQVSAYTVRNYLFELKRVEKLFSETDSWLSLQHESLQ
CCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AMLAKLHRKGLSPRSLSLTLSSLKQFYEFLLREQQIKVNPAISLTAPKQGKPLPKNMDVD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCEEEECCCCCCCCCCCCCHH
SVSHLLDLDGDDPLSLRDKAIMELFYSSGLRLAELAALNVGDIQFSQAQVKVLGKGSKER
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEECHHHHHEECCCCCCC
IVPIGKLALTAINQWLDIKRDIACEDDALFVTAKGKRLAHRSIQARLAKWGQEQAIGIKV
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEE
HPHKLRHSFATHMLESSADLRAVQELLGHANLSTTQVYTSLDFQHLAKVYDNAHPRAKKR
CHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCCHHHC
GDKA
CCCC
>Mature Secondary Structure 
ADEALSSNVRWLTDFERYLRTERQVSAYTVRNYLFELKRVEKLFSETDSWLSLQHESLQ
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
AMLAKLHRKGLSPRSLSLTLSSLKQFYEFLLREQQIKVNPAISLTAPKQGKPLPKNMDVD
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCEEECCCEEEECCCCCCCCCCCCCHH
SVSHLLDLDGDDPLSLRDKAIMELFYSSGLRLAELAALNVGDIQFSQAQVKVLGKGSKER
HHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCEECHHHHHEECCCCCCC
IVPIGKLALTAINQWLDIKRDIACEDDALFVTAKGKRLAHRSIQARLAKWGQEQAIGIKV
CCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEE
HPHKLRHSFATHMLESSADLRAVQELLGHANLSTTQVYTSLDFQHLAKVYDNAHPRAKKR
CHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHCCCCCHHHC
GDKA
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]