Click here to switch to the map view.

The map label for this gene is argB

Identifier: 157960057

GI number: 157960057

Start: 256782

End: 257585

Strand: Direct

Name: argB

Synonym: Spea_0228

Alternate gene names: 157960057

Gene position: 256782-257585 (Clockwise)

Preceding gene: 157960056

Following gene: 157960058

Centisome position: 4.96

GC content: 47.39

Gene sequence:

>804_bases
ATGACTCAAACAGATCTAAACAACACAGAACAAAAGCCAGTTATGGTGCTTAAGGTCGGCGGGGCTTTACTGCAGTGTGA
CATGGGTATGTCTCGTTTGATGCAGGCTGCCGCCAAGATAATCGCATCAGGTCAGCCGATTATTATGGTGCATGGCGGAG
GCTGCTTAGTGGATGAGCAGTTGAAAGCGAATGGCATGATAACTGAAAAACTGGATGGATTAAGAGTGACGCCAGAAGCG
CAGATCCCTGTCATCGTCGGCGCGTTAGCGGGTACCTCAAATAAGACGCTTCAGGCTGCAGCAATTAAGGCGGGCGTTAC
TTGCTTAGGTATGAGCCTAGCCGATGCTGGCATGATGAACGCCAAGATTAAAGATCCCTTGTTAGGACTGGTGGGGGAAG
TGGAGCCTAAAGATGCAAGCTATTTGGAATTTGTATTAGCAAAGGGCTGGATGCCAATTGTGAGCTCTATTGCCATTAGT
GAGCAAGGTGAGATGCTTAATGTGAACGCCGACCAAGCTGCCACAGCTTTGGCTAAGTTAGTTTCAGGATCTTTAGTTTT
GCTATCTGATGTATCTGGTGTGCTCGATGGTAAAGGGCAACTAATTAATAGCTTGAATAGGGAACAGGTTAATGAATTAA
CCAAGATAGGTGTTATTGAGAAAGGAATGAAGGTCAAAGTGGAGGCTGCATTGGATGTTGCTGAGTCCATGGGGCAAGCC
GTACAGATCGCCTCTTGGCGTCATGCACATCAGTTAATCGCATTATGCCAGGGTGAAGCCGTTGGCACACAGATCCAACC
TTAG

Upstream 100 bases:

>100_bases
CGCCATCGATAACTTAATGAAGGGCGCTGCAAGTCAAGCTCTTCAGTGCATAAAGATTCACTTTGGTGAGTCTGTTAAGT
AACTGGTGTGGAGAATTGAG

Downstream 100 bases:

>100_bases
GAGATAAGTCTTATGAAACACCTACTATCAATTAAAGATCTCAGCCAGCAGCAATTACTCGACCTATTGGCGTTGGCACA
AAACATTAAGGCTAATCCTG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 267; Mature: 266

Protein sequence:

>267_residues
MTQTDLNNTEQKPVMVLKVGGALLQCDMGMSRLMQAAAKIIASGQPIIMVHGGGCLVDEQLKANGMITEKLDGLRVTPEA
QIPVIVGALAGTSNKTLQAAAIKAGVTCLGMSLADAGMMNAKIKDPLLGLVGEVEPKDASYLEFVLAKGWMPIVSSIAIS
EQGEMLNVNADQAATALAKLVSGSLVLLSDVSGVLDGKGQLINSLNREQVNELTKIGVIEKGMKVKVEAALDVAESMGQA
VQIASWRHAHQLIALCQGEAVGTQIQP

Sequences:

>Translated_267_residues
MTQTDLNNTEQKPVMVLKVGGALLQCDMGMSRLMQAAAKIIASGQPIIMVHGGGCLVDEQLKANGMITEKLDGLRVTPEA
QIPVIVGALAGTSNKTLQAAAIKAGVTCLGMSLADAGMMNAKIKDPLLGLVGEVEPKDASYLEFVLAKGWMPIVSSIAIS
EQGEMLNVNADQAATALAKLVSGSLVLLSDVSGVLDGKGQLINSLNREQVNELTKIGVIEKGMKVKVEAALDVAESMGQA
VQIASWRHAHQLIALCQGEAVGTQIQP
>Mature_266_residues
TQTDLNNTEQKPVMVLKVGGALLQCDMGMSRLMQAAAKIIASGQPIIMVHGGGCLVDEQLKANGMITEKLDGLRVTPEAQ
IPVIVGALAGTSNKTLQAAAIKAGVTCLGMSLADAGMMNAKIKDPLLGLVGEVEPKDASYLEFVLAKGWMPIVSSIAISE
QGEMLNVNADQAATALAKLVSGSLVLLSDVSGVLDGKGQLINSLNREQVNELTKIGVIEKGMKVKVEAALDVAESMGQAV
QIASWRHAHQLIALCQGEAVGTQIQP

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=252, Percent_Identity=46.8253968253968, Blast_Score=208, Evalue=3e-55,
Organism=Saccharomyces cerevisiae, GI6320913, Length=243, Percent_Identity=27.5720164609054, Blast_Score=80, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_SHEPA (A8GZ19)

Other databases:

- EMBL:   CP000851
- RefSeq:   YP_001500091.1
- ProteinModelPortal:   A8GZ19
- SMR:   A8GZ19
- STRING:   A8GZ19
- GeneID:   5660628
- GenomeReviews:   CP000851_GR
- KEGG:   spl:Spea_0228
- NMPDR:   fig|398579.3.peg.210
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MVLCGST
- ProtClustDB:   PRK00942
- BioCyc:   SPEA398579:SPEA_0228-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 27849; Mature: 27718

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: BINDING 75-75 BINDING 167-167

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQTDLNNTEQKPVMVLKVGGALLQCDMGMSRLMQAAAKIIASGQPIIMVHGGGCLVDEQ
CCCCCCCCCCCCCEEEEEECCEEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCH
LKANGMITEKLDGLRVTPEAQIPVIVGALAGTSNKTLQAAAIKAGVTCLGMSLADAGMMN
HHCCCCEECCCCCEEECCCCCCCEEEEEECCCCCCCCHHHHHHHCHHHCCHHHHCCCCCC
AKIKDPLLGLVGEVEPKDASYLEFVLAKGWMPIVSSIAISEQGEMLNVNADQAATALAKL
CCCCCCHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
VSGSLVLLSDVSGVLDGKGQLINSLNREQVNELTKIGVIEKGMKVKVEAALDVAESMGQA
HCCCEEEEECCCHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCHH
VQIASWRHAHQLIALCQGEAVGTQIQP
EEHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TQTDLNNTEQKPVMVLKVGGALLQCDMGMSRLMQAAAKIIASGQPIIMVHGGGCLVDEQ
CCCCCCCCCCCCEEEEEECCEEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCEEECCH
LKANGMITEKLDGLRVTPEAQIPVIVGALAGTSNKTLQAAAIKAGVTCLGMSLADAGMMN
HHCCCCEECCCCCEEECCCCCCCEEEEEECCCCCCCCHHHHHHHCHHHCCHHHHCCCCCC
AKIKDPLLGLVGEVEPKDASYLEFVLAKGWMPIVSSIAISEQGEMLNVNADQAATALAKL
CCCCCCHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCCCCEEECCHHHHHHHHHHH
VSGSLVLLSDVSGVLDGKGQLINSLNREQVNELTKIGVIEKGMKVKVEAALDVAESMGQA
HCCCEEEEECCCHHHCCCHHHHHHCCHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHCHH
VQIASWRHAHQLIALCQGEAVGTQIQP
EEHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA