Click here to switch to the map view.

The map label for this gene is argE [H]

Identifier: 157960055

GI number: 157960055

Start: 254347

End: 255498

Strand: Reverse

Name: argE [H]

Synonym: Spea_0226

Alternate gene names: 157960055

Gene position: 255498-254347 (Counterclockwise)

Preceding gene: 157960061

Following gene: 157960054

Centisome position: 4.94

GC content: 46.27

Gene sequence:

>1152_bases
ATGAAGACACTTCCAGAGATAAAGAGTAGCTTTAGCCAGCTTATCGCGGCGCCTTCTATTAGCGCCCTCGAAGCCGAGTT
GGATACCAGCAACATAGCTGTCATCGAACTATTGCATACTTGGTTTAGTGATTTAGGTATGCAGTGCCAATCTGTGCCAG
TTGCCAATACGCGTAATAAGCACAATTTAGTCGCTTCATTTGGTCAAGGACAGGGAGGCTTACTATTGGCTGGGCACACG
GATACAGTGCCCTTCGATGAAGGACGCTGGAGCCAAGACCCATTTTTGTTAACTGAAAAGAATAACCGCTGGTACGGTTT
AGGTACCTGCGACATGAAAGGATTTTTTGCTTTGGTACTCGAAGCGCTAAAAGAGTTACCGATGGATAAATTTCAACGTC
CGCTGCATATCCTTGCTAGCGCAGATGAAGAAACGACCATGAATGGTGCTAAAGCCTTTGCAGCAGAGAAGTCCATTGCG
CCTGACTACGCCATCATAGGTGAGCCCACCAGCTTAAAACCTGTCTATATGCATAAGGGCCATTTAACCCAAGGGATTCG
AGTAACCGGCCGTAGCGGTCACTCATCAGATCCCGCAAAAGGCCTCAATGCTATCGAAGTGATGCACTTAGTGACTGGCC
AGCTGCTAAAACTCAAACAGCACTTAGCCAATAATTATCGAGAAGATGCCTTTAGTGTGCCCTACCCAACAATGAATTTC
GGTCATATCCACGGTGGTGATGCTGCCAATCGGATCTGTGGTTGTTGCGATCTTCATATCGACCTTCGTCCAATCCCTGG
ATTGGCATTGCAAGATTTAGAGTTGATGGTTGCCAACTATCTCGAACCAATATGTAGCCAATATCCCGGAAGTATTCACG
TAGCCCCCCTCTACCCGGGCTCAGAACCTTTTGCCGATAATAAAGAGGGCAGCTGGACACAACTCGTCGCTAAGCTCAGC
GATAGCCAGCCCGAAGTGGTGAACTATGCAACTGAAGCCCCCTATATCAGTCAATTAGGTTGTCAGACACTAGTGCTTGG
CCCTGGCAGTATCGAACAGGCTCATCAACCGGATGAATTTTTGGAGCTTAATTATATTAATCGCACAAAAGAACTATTAA
AAAAGCTGATTTATCATGCTTGTATAAAATAA

Upstream 100 bases:

>100_bases
ATCAGACCATTGAAATGTGGTAGTTGCCTTAGCTGTTTGATAGACTAACACGCAAAATTAATTATGCAATATATTTGAAT
ATATATTTGGGTATTTTTTG

Downstream 100 bases:

>100_bases
ACCTCTATTTTTCGCGTATTTAAGGGAAAAATTTAATATATCCTTAAAGATGAAATACTCAAAAAGTGGTATAAAGCCTG
TTCAAGCACGATATTTTAAT

Product: acetylornithine deacetylase

Products: NA

Alternate protein names: AO; Acetylornithinase; N-acetylornithinase; NAO [H]

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MKTLPEIKSSFSQLIAAPSISALEAELDTSNIAVIELLHTWFSDLGMQCQSVPVANTRNKHNLVASFGQGQGGLLLAGHT
DTVPFDEGRWSQDPFLLTEKNNRWYGLGTCDMKGFFALVLEALKELPMDKFQRPLHILASADEETTMNGAKAFAAEKSIA
PDYAIIGEPTSLKPVYMHKGHLTQGIRVTGRSGHSSDPAKGLNAIEVMHLVTGQLLKLKQHLANNYREDAFSVPYPTMNF
GHIHGGDAANRICGCCDLHIDLRPIPGLALQDLELMVANYLEPICSQYPGSIHVAPLYPGSEPFADNKEGSWTQLVAKLS
DSQPEVVNYATEAPYISQLGCQTLVLGPGSIEQAHQPDEFLELNYINRTKELLKKLIYHACIK

Sequences:

>Translated_383_residues
MKTLPEIKSSFSQLIAAPSISALEAELDTSNIAVIELLHTWFSDLGMQCQSVPVANTRNKHNLVASFGQGQGGLLLAGHT
DTVPFDEGRWSQDPFLLTEKNNRWYGLGTCDMKGFFALVLEALKELPMDKFQRPLHILASADEETTMNGAKAFAAEKSIA
PDYAIIGEPTSLKPVYMHKGHLTQGIRVTGRSGHSSDPAKGLNAIEVMHLVTGQLLKLKQHLANNYREDAFSVPYPTMNF
GHIHGGDAANRICGCCDLHIDLRPIPGLALQDLELMVANYLEPICSQYPGSIHVAPLYPGSEPFADNKEGSWTQLVAKLS
DSQPEVVNYATEAPYISQLGCQTLVLGPGSIEQAHQPDEFLELNYINRTKELLKKLIYHACIK
>Mature_383_residues
MKTLPEIKSSFSQLIAAPSISALEAELDTSNIAVIELLHTWFSDLGMQCQSVPVANTRNKHNLVASFGQGQGGLLLAGHT
DTVPFDEGRWSQDPFLLTEKNNRWYGLGTCDMKGFFALVLEALKELPMDKFQRPLHILASADEETTMNGAKAFAAEKSIA
PDYAIIGEPTSLKPVYMHKGHLTQGIRVTGRSGHSSDPAKGLNAIEVMHLVTGQLLKLKQHLANNYREDAFSVPYPTMNF
GHIHGGDAANRICGCCDLHIDLRPIPGLALQDLELMVANYLEPICSQYPGSIHVAPLYPGSEPFADNKEGSWTQLVAKLS
DSQPEVVNYATEAPYISQLGCQTLVLGPGSIEQAHQPDEFLELNYINRTKELLKKLIYHACIK

Specific function: Displays A Broad Specificity And Can Also Deacylate Substrates Such As Acetylarginine, Acetylhistidine Or Acetylglutamate Semialdehyde. [C]

COG id: COG0624

COG function: function code E; Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M20A family. ArgE subfamily [H]

Homologues:

Organism=Homo sapiens, GI4501901, Length=355, Percent_Identity=24.7887323943662, Blast_Score=73, Evalue=6e-13,
Organism=Escherichia coli, GI1790395, Length=378, Percent_Identity=55.026455026455, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI1788816, Length=357, Percent_Identity=24.6498599439776, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17551016, Length=344, Percent_Identity=27.3255813953488, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010169
- InterPro:   IPR001261
- InterPro:   IPR002933
- InterPro:   IPR011650 [H]

Pfam domain/function: PF07687 M20_dimer; PF01546 Peptidase_M20 [H]

EC number: =3.5.1.16 [H]

Molecular weight: Translated: 42048; Mature: 42048

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS00758 ARGE_DAPE_CPG2_1 ; PS00759 ARGE_DAPE_CPG2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLPEIKSSFSQLIAAPSISALEAELDTSNIAVIELLHTWFSDLGMQCQSVPVANTRNK
CCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
HNLVASFGQGQGGLLLAGHTDTVPFDEGRWSQDPFLLTEKNNRWYGLGTCDMKGFFALVL
CCCEEECCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHH
EALKELPMDKFQRPLHILASADEETTMNGAKAFAAEKSIAPDYAIIGEPTSLKPVYMHKG
HHHHHCCHHHHHCCCEEHHCCCCHHHCCHHHHHHHHCCCCCCEEEECCCCCCCEEEEECC
HLTQGIRVTGRSGHSSDPAKGLNAIEVMHLVTGQLLKLKQHLANNYREDAFSVPYPTMNF
CCCCCEEEECCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GHIHGGDAANRICGCCDLHIDLRPIPGLALQDLELMVANYLEPICSQYPGSIHVAPLYPG
CCCCCCCHHHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SEPFADNKEGSWTQLVAKLSDSQPEVVNYATEAPYISQLGCQTLVLGPGSIEQAHQPDEF
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCHHHHCCCCEEEECCCCCCCCCCCCHH
LELNYINRTKELLKKLIYHACIK
EEEHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTLPEIKSSFSQLIAAPSISALEAELDTSNIAVIELLHTWFSDLGMQCQSVPVANTRNK
CCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
HNLVASFGQGQGGLLLAGHTDTVPFDEGRWSQDPFLLTEKNNRWYGLGTCDMKGFFALVL
CCCEEECCCCCCCEEEECCCCCCCCCCCCCCCCCEEEEECCCCEEEEECCCHHHHHHHHH
EALKELPMDKFQRPLHILASADEETTMNGAKAFAAEKSIAPDYAIIGEPTSLKPVYMHKG
HHHHHCCHHHHHCCCEEHHCCCCHHHCCHHHHHHHHCCCCCCEEEECCCCCCCEEEEECC
HLTQGIRVTGRSGHSSDPAKGLNAIEVMHLVTGQLLKLKQHLANNYREDAFSVPYPTMNF
CCCCCEEEECCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GHIHGGDAANRICGCCDLHIDLRPIPGLALQDLELMVANYLEPICSQYPGSIHVAPLYPG
CCCCCCCHHHHHEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SEPFADNKEGSWTQLVAKLSDSQPEVVNYATEAPYISQLGCQTLVLGPGSIEQAHQPDEF
CCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCHHHHCCCCEEEECCCCCCCCCCCCHH
LELNYINRTKELLKKLIYHACIK
EEEHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA