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The map label for this gene is ccmB [H]

Identifier: 157960043

GI number: 157960043

Start: 226489

End: 227175

Strand: Reverse

Name: ccmB [H]

Synonym: Spea_0214

Alternate gene names: 157960043

Gene position: 227175-226489 (Counterclockwise)

Preceding gene: 157960044

Following gene: 157960042

Centisome position: 4.39

GC content: 44.4

Gene sequence:

>687_bases
ATGAAGAAAGGCATCAGTTATACCAAAGCATTTAGCACGCTGTTAAAGCGTGATCTGCAAATAGCAGTGCGCCATCGCGG
TGACATTTTTAACCCGCTACTGTTTTTTGTCCTAGTGGTAACACTCTTCCCTCTAGGTATTGGTCCAGAACCACAAGTAT
TAACTCGAGTTGCACCTGGTATTATTTGGGTCGCAGCACTTTTGGCATCAATGTTATCGCTTGAACGTTTGTTTAAGGCA
GATTACGCCGATGGTAGCCTTGAACAAATGCTATTAAGCCCTCAACCGCTACCTCTAATGGTGTTAGCCAAGGTGTTAGC
GCATTGGATATTGACAGGCGTGCCTTTGATTTTGGTGGCACCATTACTAGCGGTGTTGTTGCATTTAGAAAGCAATAGCT
ACGGCGCGTTGATTGCGACGCTTGCGCTAGGGACTCCCGTGCTGAGCTTGCTCGGAGCCATTGGTGTTGCACTAACAGTT
GGATTACGTAAAGGTGGTGTGCTTTTAAGCCTGTTAATTTTACCTTTATATATTCCAGTTCTAATTTTTGCTACTAGCGC
GATTGACGCTGCTGGTATGAATTTACCTTATGATGGTCAACTCGCTATTATTGGCGCAATGTTGGTCGGTTCATTAACGT
TAGCACCATTTGCAATTGGTGCATCCTTACGAGTGAGTACTAACTAA

Upstream 100 bases:

>100_bases
CGGTTGCGTAATATTAACCACACACCAAGATATGGGTGTGATTGGCGATGATATTCTACGTAAAATCCGTCTCGATTATC
GCTTTGTATAAGGTTTGGTA

Downstream 100 bases:

>100_bases
AATGTGGAAATGGTTACATTCATACGCGGATCCTGAACGCGCCTACAAACTCTCAGGCACCCTACTACCTTGGTTTGCCA
TGCTTGCAATATCGATGATT

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MKKGISYTKAFSTLLKRDLQIAVRHRGDIFNPLLFFVLVVTLFPLGIGPEPQVLTRVAPGIIWVAALLASMLSLERLFKA
DYADGSLEQMLLSPQPLPLMVLAKVLAHWILTGVPLILVAPLLAVLLHLESNSYGALIATLALGTPVLSLLGAIGVALTV
GLRKGGVLLSLLILPLYIPVLIFATSAIDAAGMNLPYDGQLAIIGAMLVGSLTLAPFAIGASLRVSTN

Sequences:

>Translated_228_residues
MKKGISYTKAFSTLLKRDLQIAVRHRGDIFNPLLFFVLVVTLFPLGIGPEPQVLTRVAPGIIWVAALLASMLSLERLFKA
DYADGSLEQMLLSPQPLPLMVLAKVLAHWILTGVPLILVAPLLAVLLHLESNSYGALIATLALGTPVLSLLGAIGVALTV
GLRKGGVLLSLLILPLYIPVLIFATSAIDAAGMNLPYDGQLAIIGAMLVGSLTLAPFAIGASLRVSTN
>Mature_228_residues
MKKGISYTKAFSTLLKRDLQIAVRHRGDIFNPLLFFVLVVTLFPLGIGPEPQVLTRVAPGIIWVAALLASMLSLERLFKA
DYADGSLEQMLLSPQPLPLMVLAKVLAHWILTGVPLILVAPLLAVLLHLESNSYGALIATLALGTPVLSLLGAIGVALTV
GLRKGGVLLSLLILPLYIPVLIFATSAIDAAGMNLPYDGQLAIIGAMLVGSLTLAPFAIGASLRVSTN

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=218, Percent_Identity=60.5504587155963, Blast_Score=218, Evalue=2e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 24063; Mature: 24063

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGISYTKAFSTLLKRDLQIAVRHRGDIFNPLLFFVLVVTLFPLGIGPEPQVLTRVAPG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IIWVAALLASMLSLERLFKADYADGSLEQMLLSPQPLPLMVLAKVLAHWILTGVPLILVA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
PLLAVLLHLESNSYGALIATLALGTPVLSLLGAIGVALTVGLRKGGVLLSLLILPLYIPV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LIFATSAIDAAGMNLPYDGQLAIIGAMLVGSLTLAPFAIGASLRVSTN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCC
>Mature Secondary Structure
MKKGISYTKAFSTLLKRDLQIAVRHRGDIFNPLLFFVLVVTLFPLGIGPEPQVLTRVAPG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
IIWVAALLASMLSLERLFKADYADGSLEQMLLSPQPLPLMVLAKVLAHWILTGVPLILVA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
PLLAVLLHLESNSYGALIATLALGTPVLSLLGAIGVALTVGLRKGGVLLSLLILPLYIPV
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LIFATSAIDAAGMNLPYDGQLAIIGAMLVGSLTLAPFAIGASLRVSTN
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]