BacMap

Definition	Shewanella pealeana ATCC 700345 chromosome, complete genome.
Accession	NC_009901
Length	5,174,581

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The map label for this gene is ccmA [H]

Identifier: 157960044

GI number: 157960044

Start: 227185

End: 227835

Strand: Reverse

Name: ccmA [H]

Synonym: Spea_0215

Alternate gene names: 157960044

Gene position: 227835-227185 (Counterclockwise)

Preceding gene: 157960046

Following gene: 157960043

Centisome position: 4.4

GC content: 42.24

Gene sequence:

>651_bases
GTGGTAAAAGAATCAAAAGCAACAACACTGGTATCAGCTAATAACTTAACTTGCATAAGGGAAGAACGCATTTTATTTGA
TGAACTTAGCTTCGATATAACCGAAGGTGAGATTGTTCAAATTGAAGGCCCTAACGGTGCAGGTAAAACAAGTCTTTTGC
GGATCATCGCAGGTTTATCTCGCCCTTATGCAGGGCAAATCAACTTCAAAGGTGAAGACATTAACCGTTGTCGTGACGAG
TACAATGATGAATTGTTGTACCTTGGCCACCTTGCAGGTGTTAAAAGTGAGTTAACGGCTGAAGAAAATCTTAACTTCAA
TTTAAGGATCAGTGGGTATGATGATTTCGATGCCCGTCAGATCCTTGCAAAAGTCAATCTCTCAGGTTTTGAAGAAGCGC
TCGCAGGACACTTATCGGCAGGCCAACACAGACGTACAGCCCTTGCTAGGCTCTGGCACACTAACTGTAAGATATGGCTG
CTAGATGAGCCTTTTACTGCTATCGATAAAAAAGGCGTAGAAGAACTTGAACACCTATTTTTAGCCCATGCAAAACGCGG
CGGTTGCGTAATATTAACCACACACCAAGATATGGGTGTGATTGGCGATGATATTCTACGTAAAATCCGTCTCGATTATC
GCTTTGTATAA

Upstream 100 bases:

>100_bases
CATCAAATTGCTGACACTTAGCAACAAGCAAGACTAAACGCTTGAAAGTGTATGTGTTAGTATCTCTTGTGTTTTCATAC
AGCTTGATATAGAGGGCTCA

Downstream 100 bases:

>100_bases
GGTTTGGTAATGAAGAAAGGCATCAGTTATACCAAAGCATTTAGCACGCTGTTAAAGCGTGATCTGCAAATAGCAGTGCG
CCATCGCGGTGACATTTTTA

Product: cytochrome c biogenesis protein CcmA

Products: NA

Alternate protein names: Heme exporter protein A [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MVKESKATTLVSANNLTCIREERILFDELSFDITEGEIVQIEGPNGAGKTSLLRIIAGLSRPYAGQINFKGEDINRCRDE
YNDELLYLGHLAGVKSELTAEENLNFNLRISGYDDFDARQILAKVNLSGFEEALAGHLSAGQHRRTALARLWHTNCKIWL
LDEPFTAIDKKGVEELEHLFLAHAKRGGCVILTTHQDMGVIGDDILRKIRLDYRFV

Sequences:

>Translated_216_residues
MVKESKATTLVSANNLTCIREERILFDELSFDITEGEIVQIEGPNGAGKTSLLRIIAGLSRPYAGQINFKGEDINRCRDE
YNDELLYLGHLAGVKSELTAEENLNFNLRISGYDDFDARQILAKVNLSGFEEALAGHLSAGQHRRTALARLWHTNCKIWL
LDEPFTAIDKKGVEELEHLFLAHAKRGGCVILTTHQDMGVIGDDILRKIRLDYRFV
>Mature_216_residues
MVKESKATTLVSANNLTCIREERILFDELSFDITEGEIVQIEGPNGAGKTSLLRIIAGLSRPYAGQINFKGEDINRCRDE
YNDELLYLGHLAGVKSELTAEENLNFNLRISGYDDFDARQILAKVNLSGFEEALAGHLSAGQHRRTALARLWHTNCKIWL
LDEPFTAIDKKGVEELEHLFLAHAKRGGCVILTTHQDMGVIGDDILRKIRLDYRFV

Specific function: Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system [H]

COG id: COG4133

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI27436953, Length=190, Percent_Identity=33.6842105263158, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI153792144, Length=186, Percent_Identity=28.494623655914, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI45446740, Length=191, Percent_Identity=27.7486910994764, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI47078218, Length=191, Percent_Identity=28.2722513089005, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI21536376, Length=207, Percent_Identity=28.0193236714976, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI11967969, Length=198, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI27262624, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI27262626, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI150417984, Length=196, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI27477115, Length=176, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI105990541, Length=203, Percent_Identity=28.0788177339901, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI87082064, Length=202, Percent_Identity=49.009900990099, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI87081709, Length=164, Percent_Identity=32.9268292682927, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI87081791, Length=199, Percent_Identity=31.6582914572864, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1788761, Length=160, Percent_Identity=35.625, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI2367384, Length=190, Percent_Identity=31.0526315789474, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786563, Length=179, Percent_Identity=30.7262569832402, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1787029, Length=179, Percent_Identity=32.9608938547486, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786253, Length=151, Percent_Identity=33.112582781457, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1787105, Length=179, Percent_Identity=29.608938547486, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789873, Length=178, Percent_Identity=30.8988764044944, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787370, Length=176, Percent_Identity=30.1136363636364, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1788165, Length=195, Percent_Identity=28.7179487179487, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1787089, Length=199, Percent_Identity=26.1306532663317, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081782, Length=166, Percent_Identity=30.7228915662651, Blast_Score=72, Evalue=2e-14,
Organism=Escherichia coli, GI1789593, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790467, Length=194, Percent_Identity=28.8659793814433, Blast_Score=71, Evalue=5e-14,
Organism=Escherichia coli, GI87081834, Length=179, Percent_Identity=26.2569832402235, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI87082267, Length=154, Percent_Identity=27.9220779220779, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789032, Length=176, Percent_Identity=27.2727272727273, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1787712, Length=203, Percent_Identity=27.0935960591133, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789991, Length=193, Percent_Identity=26.4248704663212, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786698, Length=199, Percent_Identity=27.6381909547739, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789586, Length=178, Percent_Identity=30.3370786516854, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1786872, Length=166, Percent_Identity=28.3132530120482, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48994997, Length=204, Percent_Identity=26.4705882352941, Blast_Score=62, Evalue=2e-11,
Organism=Escherichia coli, GI87082268, Length=144, Percent_Identity=31.25, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17565586, Length=188, Percent_Identity=26.5957446808511, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI115533608, Length=185, Percent_Identity=29.7297297297297, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17510237, Length=172, Percent_Identity=28.4883720930233, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24666092, Length=184, Percent_Identity=31.5217391304348, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24648314, Length=178, Percent_Identity=28.0898876404494, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI28573571, Length=203, Percent_Identity=27.0935960591133, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28574150, Length=192, Percent_Identity=29.6875, Blast_Score=67, Evalue=8e-12,
Organism=Drosophila melanogaster, GI116007328, Length=192, Percent_Identity=29.6875, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI28573573, Length=198, Percent_Identity=26.7676767676768, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI28574744, Length=185, Percent_Identity=27.027027027027, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR005895
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.41 [H]

Molecular weight: Translated: 24286; Mature: 24286

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKESKATTLVSANNLTCIREERILFDELSFDITEGEIVQIEGPNGAGKTSLLRIIAGLS
CCCCCCCEEEEECCCEEEEECCCCEEHHCCEEECCCEEEEEECCCCCCHHHHHHHHHHCC
RPYAGQINFKGEDINRCRDEYNDELLYLGHLAGVKSELTAEENLNFNLRISGYDDFDARQ
CCCCCEEEECCCHHHHHHHHHCCCEEEEEHHHCCHHHCCHHCCCCEEEEECCCCCHHHHH
ILAKVNLSGFEEALAGHLSAGQHRRTALARLWHTNCKIWLLDEPFTAIDKKGVEELEHLF
HHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHH
LAHAKRGGCVILTTHQDMGVIGDDILRKIRLDYRFV
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCEECC
>Mature Secondary Structure
MVKESKATTLVSANNLTCIREERILFDELSFDITEGEIVQIEGPNGAGKTSLLRIIAGLS
CCCCCCCEEEEECCCEEEEECCCCEEHHCCEEECCCEEEEEECCCCCCHHHHHHHHHHCC
RPYAGQINFKGEDINRCRDEYNDELLYLGHLAGVKSELTAEENLNFNLRISGYDDFDARQ
CCCCCEEEECCCHHHHHHHHHCCCEEEEEHHHCCHHHCCHHCCCCEEEEECCCCCHHHHH
ILAKVNLSGFEEALAGHLSAGQHRRTALARLWHTNCKIWLLDEPFTAIDKKGVEELEHLF
HHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHH
LAHAKRGGCVILTTHQDMGVIGDDILRKIRLDYRFV
HHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]