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The map label for this gene is murB [H]

Identifier: 157959997

GI number: 157959997

Start: 188407

End: 189432

Strand: Direct

Name: murB [H]

Synonym: Spea_0167

Alternate gene names: 157959997

Gene position: 188407-189432 (Clockwise)

Preceding gene: 157959995

Following gene: 157959998

Centisome position: 3.64

GC content: 40.94

Gene sequence:

>1026_bases
ATGCCAACCTGCCAATCATATTCATTACAACCTCATAATACGTTCGCGTTAGCGCATTCGTGTCGTCGATTAGTTCATGC
GTCCTCTACCGCCCAGCTGGTTGAAGTCTGTCGTGAGCTATACCTTACTAAAGAGCCAATGCTGATTTTAGGTGGTGGTA
GCAATATTATCCTTTGTGATGATTTCGAAGGTACGGTAGTGCTTGTTGAAACGAAAGGTATTGAAGTTTCAGAATCTGAA
ACTTACTACGATCTTTCGGTTGCTGCTGGAGAGAATTGGCACGATCTTGTTTGTTTTTGTTTAGCTAACGGCTTTCCAGG
GTTAGAGAATTTAGCACTGATCCCTGGGACTGTTGGCGCAGCTCCTATTCAAAATATCGGCGCTTATGGTGTTGAACTAT
ATGATTTTTGTAGTTGGGTTGAATATGTAGATCTGCACAAAGGCCAGCGAGTAAAATTACAGGCAGGTGACTGCGGTTTT
GGTTACAGAGATTCTATTTTCAAACGTTGTTTATTAGGTAAGGCAATCATTACTCGAGTTGGACTTAAGTTGCCTAAAGC
ATGGACTCCGAAACTGGAATATGGGCCACTTAAAGCATTAAGCGGTACTGAAGTAACCCCGAAACAAGTTTTTGACTGTA
TTTGTGATACTAGAAAATCCAAGTTGCCGGATCCTAAAGACTTTGGCAATGCTGGCAGTTTTTTTAAAAACCCTGTTATT
GATGATAAACAATTCGAAAGCTTGCTTGAGCGCTATCCAAGTATTGTGGGTTATTCAAATTCCTCAGGTAAAACTAAAGT
TGCAGCAGGCTGGTTAATCGATTGTGCTGGCTTAAAAGGTTATCAAATTGGCGGTGCAGCAGTACACGAAAACCAAGCCT
TGGTACTAATTAACAAATGTAATGCTACAAGTGAGGATGTGCTGTCACTCGCTAGATTTGTTGTTGATAAGATAAATGAA
GTTTTTGGTATCCAACTAGAACCTGAGCCTAGAATGATTAGCGCTAATGGAGAGAGGAGTTTATAG

Upstream 100 bases:

>100_bases
TTCTTTCATTGTCCAATCGCTACTACTGGAGGCGTGCACGAAGCTTCTGCGAACCGCTTGTTTAGGCTACAATAGCTTTT
TACCTGTCAACGATACTCAG

Downstream 100 bases:

>100_bases
CATGGTTGAGCAGTGGAGTCGCAAACGAGAAATCCTCTCAGAGCTAGCATCAGGGAAATTTGTATCTGGGGAAGCATTGG
CATCAATTCTTGGTGTCTCT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 341; Mature: 340

Protein sequence:

>341_residues
MPTCQSYSLQPHNTFALAHSCRRLVHASSTAQLVEVCRELYLTKEPMLILGGGSNIILCDDFEGTVVLVETKGIEVSESE
TYYDLSVAAGENWHDLVCFCLANGFPGLENLALIPGTVGAAPIQNIGAYGVELYDFCSWVEYVDLHKGQRVKLQAGDCGF
GYRDSIFKRCLLGKAIITRVGLKLPKAWTPKLEYGPLKALSGTEVTPKQVFDCICDTRKSKLPDPKDFGNAGSFFKNPVI
DDKQFESLLERYPSIVGYSNSSGKTKVAAGWLIDCAGLKGYQIGGAAVHENQALVLINKCNATSEDVLSLARFVVDKINE
VFGIQLEPEPRMISANGERSL

Sequences:

>Translated_341_residues
MPTCQSYSLQPHNTFALAHSCRRLVHASSTAQLVEVCRELYLTKEPMLILGGGSNIILCDDFEGTVVLVETKGIEVSESE
TYYDLSVAAGENWHDLVCFCLANGFPGLENLALIPGTVGAAPIQNIGAYGVELYDFCSWVEYVDLHKGQRVKLQAGDCGF
GYRDSIFKRCLLGKAIITRVGLKLPKAWTPKLEYGPLKALSGTEVTPKQVFDCICDTRKSKLPDPKDFGNAGSFFKNPVI
DDKQFESLLERYPSIVGYSNSSGKTKVAAGWLIDCAGLKGYQIGGAAVHENQALVLINKCNATSEDVLSLARFVVDKINE
VFGIQLEPEPRMISANGERSL
>Mature_340_residues
PTCQSYSLQPHNTFALAHSCRRLVHASSTAQLVEVCRELYLTKEPMLILGGGSNIILCDDFEGTVVLVETKGIEVSESET
YYDLSVAAGENWHDLVCFCLANGFPGLENLALIPGTVGAAPIQNIGAYGVELYDFCSWVEYVDLHKGQRVKLQAGDCGFG
YRDSIFKRCLLGKAIITRVGLKLPKAWTPKLEYGPLKALSGTEVTPKQVFDCICDTRKSKLPDPKDFGNAGSFFKNPVID
DKQFESLLERYPSIVGYSNSSGKTKVAAGWLIDCAGLKGYQIGGAAVHENQALVLINKCNATSEDVLSLARFVVDKINEV
FGIQLEPEPRMISANGERSL

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Escherichia coli, GI1790407, Length=335, Percent_Identity=52.2388059701493, Blast_Score=352, Evalue=2e-98,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 37242; Mature: 37111

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTCQSYSLQPHNTFALAHSCRRLVHASSTAQLVEVCRELYLTKEPMLILGGGSNIILCD
CCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEEE
DFEGTVVLVETKGIEVSESETYYDLSVAAGENWHDLVCFCLANGFPGLENLALIPGTVGA
CCCCEEEEEEECCCEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEECCCCCCC
APIQNIGAYGVELYDFCSWVEYVDLHKGQRVKLQAGDCGFGYRDSIFKRCLLGKAIITRV
CCHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
GLKLPKAWTPKLEYGPLKALSGTEVTPKQVFDCICDTRKSKLPDPKDFGNAGSFFKNPVI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCCHHCCCCC
DDKQFESLLERYPSIVGYSNSSGKTKVAAGWLIDCAGLKGYQIGGAAVHENQALVLINKC
CHHHHHHHHHHCCHHEECCCCCCCEEEEEEEEEEECCCCCEECCCEEEECCCEEEEEECC
NATSEDVLSLARFVVDKINEVFGIQLEPEPRMISANGERSL
CCCHHHHHHHHHHHHHHHHHHHCEEECCCCCEEECCCCCCC
>Mature Secondary Structure 
PTCQSYSLQPHNTFALAHSCRRLVHASSTAQLVEVCRELYLTKEPMLILGGGSNIILCD
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEEE
DFEGTVVLVETKGIEVSESETYYDLSVAAGENWHDLVCFCLANGFPGLENLALIPGTVGA
CCCCEEEEEEECCCEECCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCEECCCCCCC
APIQNIGAYGVELYDFCSWVEYVDLHKGQRVKLQAGDCGFGYRDSIFKRCLLGKAIITRV
CCHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
GLKLPKAWTPKLEYGPLKALSGTEVTPKQVFDCICDTRKSKLPDPKDFGNAGSFFKNPVI
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHCCCCCCHHCCCCC
DDKQFESLLERYPSIVGYSNSSGKTKVAAGWLIDCAGLKGYQIGGAAVHENQALVLINKC
CHHHHHHHHHHCCHHEECCCCCCCEEEEEEEEEEECCCCCEECCCEEEECCCEEEEEECC
NATSEDVLSLARFVVDKINEVFGIQLEPEPRMISANGERSL
CCCHHHHHHHHHHHHHHHHHHHCEEECCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA