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The map label for this gene is neuA [H]

Identifier: 157959882

GI number: 157959882

Start: 68035

End: 68727

Strand: Direct

Name: neuA [H]

Synonym: Spea_0052

Alternate gene names: 157959882

Gene position: 68035-68727 (Clockwise)

Preceding gene: 157959881

Following gene: 157959906

Centisome position: 1.31

GC content: 38.67

Gene sequence:

>693_bases
ATGATTAAAAATAAACGAGTGTTAGCTCTTATTCCCGCAAGAGGTGGAAGTAAGAGGTTACCTCGAAAAAATATATTACC
TTTGGCAGGCATACCTTTAATAGCCTGGACGATAGACGCTGCTCTTAAATCAAAGTATATCGACCGAGTTGTGGTCTCTA
CTGACGATGAAGAGATTATGTGTGTCAGCAAGCAATTTGGAGCCGAAGCCCCCTTTGTTAGGCCTGTTGAGCTTGCGTCA
GATACTGCAACATCTACAGACGTCGTTCTTCATGCGTTAAATTTTTTTAAGAATGATTTTGATGTGATTGTTTTATTGCA
GCCATCGTCCCCGCTAAGGGAAGAGAGTGATATCGATAGGGTTATTGAGCAGTTAGTCAGCCAAGACGCAAATGGTATAG
TTTCAGTAAGTGAGTGTGAGCACACTCCATTGTGGTCAAATACTTTACCGGCTGATGGAAACATGTCTTCATTTATAACA
AAAGATGCGCTTAAGCGTTCTCAAGATTTAAAAACATTTTACAGGTTAAATGGGGCGATTTATTGTTATAAGACTGATTA
TTTTATAGCGAATCAAGGAGGTAGCTACGCTGATGGTGTATATGCTTGTATCATGAAAAAAGAAAAGTCAGTTGATATCG
ATGATATAACCGACTTTAAATTTGCAGAGTTTCTTATTGGTCTTTATCGCTAA

Upstream 100 bases:

>100_bases
AAAACGTTTTAATGTTTCCGGTTCATGAATATTGGCTTGATATTGGTCGAATGGCTGATTTTGAACGAGCTCAAACAGAT
ATTTTAAGTTTAGGTTTGTA

Downstream 100 bases:

>100_bases
CTTTTTTAAATTAAACCAGACTATATTGGTCTGGTGATTTAAGTGCCACTACTGAAAGAAAAAGAAATAACCGACTAGGC
AGAAAGAAAGTAATGCCCCG

Product: acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: CMP-N-acetylneuraminic acid synthase; CMP-NeuNAc synthase; CMP-sialic acid synthase [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MIKNKRVLALIPARGGSKRLPRKNILPLAGIPLIAWTIDAALKSKYIDRVVVSTDDEEIMCVSKQFGAEAPFVRPVELAS
DTATSTDVVLHALNFFKNDFDVIVLLQPSSPLREESDIDRVIEQLVSQDANGIVSVSECEHTPLWSNTLPADGNMSSFIT
KDALKRSQDLKTFYRLNGAIYCYKTDYFIANQGGSYADGVYACIMKKEKSVDIDDITDFKFAEFLIGLYR

Sequences:

>Translated_230_residues
MIKNKRVLALIPARGGSKRLPRKNILPLAGIPLIAWTIDAALKSKYIDRVVVSTDDEEIMCVSKQFGAEAPFVRPVELAS
DTATSTDVVLHALNFFKNDFDVIVLLQPSSPLREESDIDRVIEQLVSQDANGIVSVSECEHTPLWSNTLPADGNMSSFIT
KDALKRSQDLKTFYRLNGAIYCYKTDYFIANQGGSYADGVYACIMKKEKSVDIDDITDFKFAEFLIGLYR
>Mature_230_residues
MIKNKRVLALIPARGGSKRLPRKNILPLAGIPLIAWTIDAALKSKYIDRVVVSTDDEEIMCVSKQFGAEAPFVRPVELAS
DTATSTDVVLHALNFFKNDFDVIVLLQPSSPLREESDIDRVIEQLVSQDANGIVSVSECEHTPLWSNTLPADGNMSSFIT
KDALKRSQDLKTFYRLNGAIYCYKTDYFIANQGGSYADGVYACIMKKEKSVDIDDITDFKFAEFLIGLYR

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CMP-NeuNAc synthase family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=219, Percent_Identity=36.986301369863, Blast_Score=111, Evalue=4e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003329 [H]

Pfam domain/function: PF02348 CTP_transf_3 [H]

EC number: =2.7.7.43 [H]

Molecular weight: Translated: 25654; Mature: 25654

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKNKRVLALIPARGGSKRLPRKNILPLAGIPLIAWTIDAALKSKYIDRVVVSTDDEEIM
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCEE
CVSKQFGAEAPFVRPVELASDTATSTDVVLHALNFFKNDFDVIVLLQPSSPLREESDIDR
EEEHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHH
VIEQLVSQDANGIVSVSECEHTPLWSNTLPADGNMSSFITKDALKRSQDLKTFYRLNGAI
HHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEE
YCYKTDYFIANQGGSYADGVYACIMKKEKSVDIDDITDFKFAEFLIGLYR
EEEECCEEEECCCCCCCCHHEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MIKNKRVLALIPARGGSKRLPRKNILPLAGIPLIAWTIDAALKSKYIDRVVVSTDDEEIM
CCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCEEEEECCCCCEE
CVSKQFGAEAPFVRPVELASDTATSTDVVLHALNFFKNDFDVIVLLQPSSPLREESDIDR
EEEHHCCCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHH
VIEQLVSQDANGIVSVSECEHTPLWSNTLPADGNMSSFITKDALKRSQDLKTFYRLNGAI
HHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEE
YCYKTDYFIANQGGSYADGVYACIMKKEKSVDIDDITDFKFAEFLIGLYR
EEEECCEEEECCCCCCCCHHEEEEECCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1398032; 7830552; 8113198; 8045888; 10710307 [H]