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The map label for this gene is mpg1 [H]

Identifier: 157959881

GI number: 157959881

Start: 66980

End: 68035

Strand: Direct

Name: mpg1 [H]

Synonym: Spea_0051

Alternate gene names: 157959881

Gene position: 66980-68035 (Clockwise)

Preceding gene: 157959880

Following gene: 157959882

Centisome position: 1.29

GC content: 37.88

Gene sequence:

>1056_bases
ATGAGTAACTCTTGGAAAAATATTTTAATAAAACCTGAGGCGACAATACTTGATGCTCTTGGGGTTATCGATAATGAAGC
ATTGCAAGTTGCCTTAGTAGTTAATAGTGAACAAAAACTATTAGGTGTAATAACCGATGGTGATATTCGTCGGGGGATAC
TTAATAATTTGTCATTAGACACTCCCGTCACCGAAATAATGAATTGCTCACCAATTACAGCAGAGATGAGCTCAACGAAA
GAGCAATTGACACAATTAATGGAAAGTAAGAGCATACTTGCGATTCCGTTAATTGAAAACGGCAAAGTTGTTGGTTTAGA
AACATTACAGAGATTACTTGAAACAACAATCTATCAAAACCCTGTATTTATAATGGCGGGAGGGTTTGGTACTCGCTTAA
GGCCTTTAACAGATTCCTGTCCAAAACCGATGTTGAAAGTTGGTGACAAGCCAATATTGGATATATTAATTACTAACTTT
ATTAAAGCTGGTTTTGTCAATTTCTATATATCAACACATTATATGGCTGAGCAAATTCGAAGCTACTTCGGTGATGGTAG
TGAGTTAGGAGTGAAAATTCATTATATTCATGAAGAGGCTCCATTAGGTACGGGGGGAGCACTTGGTTTACTGCCTGACG
ACTTACCAAAAGGCTTACCTTTGATCATGGTGAATGGAGATGTGCTCACCAAGGTTGATTTTGAAAGGCTATTAGATTTT
CATAATGAGCATCAGGCCGATGCCACCATGTGTGTACGAAAGTATGATTATCAAGTTCCCTATGGCGTTGTTAGTGGCGA
AGGGAACAAGGTTACCTGCATGGTTGAAAAGCCGGTTCAACATTTTTTTGTTAACGCAGGCATTTATGTCATATCTCCAT
GTGTGATTGATTCTGTGCCTAAAGATTATCATATCGATATGCCTACTCTATTGGATCAGCATATGAGTGAGCGTGAAAAC
GTTTTAATGTTTCCGGTTCATGAATATTGGCTTGATATTGGTCGAATGGCTGATTTTGAACGAGCTCAAACAGATATTTT
AAGTTTAGGTTTGTAA

Upstream 100 bases:

>100_bases
GTTATTGGAGCCGGTGCTATCGTTACTAAAAATGTATCATCAGGAAAAGTTTGCTATTCAAGTCGAATAATAATGAATTG
AAAATAGCTAAAGGTTAATC

Downstream 100 bases:

>100_bases
TGATTAAAAATAAACGAGTGTTAGCTCTTATTCCCGCAAGAGGTGGAAGTAAGAGGTTACCTCGAAAAAATATATTACCT
TTGGCAGGCATACCTTTAAT

Product: nucleotidyl transferase

Products: NA

Alternate protein names: ATP-mannose-1-phosphate guanylyltransferase; GDP-mannose pyrophosphorylase; NDP-hexose pyrophosphorylase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MSNSWKNILIKPEATILDALGVIDNEALQVALVVNSEQKLLGVITDGDIRRGILNNLSLDTPVTEIMNCSPITAEMSSTK
EQLTQLMESKSILAIPLIENGKVVGLETLQRLLETTIYQNPVFIMAGGFGTRLRPLTDSCPKPMLKVGDKPILDILITNF
IKAGFVNFYISTHYMAEQIRSYFGDGSELGVKIHYIHEEAPLGTGGALGLLPDDLPKGLPLIMVNGDVLTKVDFERLLDF
HNEHQADATMCVRKYDYQVPYGVVSGEGNKVTCMVEKPVQHFFVNAGIYVISPCVIDSVPKDYHIDMPTLLDQHMSEREN
VLMFPVHEYWLDIGRMADFERAQTDILSLGL

Sequences:

>Translated_351_residues
MSNSWKNILIKPEATILDALGVIDNEALQVALVVNSEQKLLGVITDGDIRRGILNNLSLDTPVTEIMNCSPITAEMSSTK
EQLTQLMESKSILAIPLIENGKVVGLETLQRLLETTIYQNPVFIMAGGFGTRLRPLTDSCPKPMLKVGDKPILDILITNF
IKAGFVNFYISTHYMAEQIRSYFGDGSELGVKIHYIHEEAPLGTGGALGLLPDDLPKGLPLIMVNGDVLTKVDFERLLDF
HNEHQADATMCVRKYDYQVPYGVVSGEGNKVTCMVEKPVQHFFVNAGIYVISPCVIDSVPKDYHIDMPTLLDQHMSEREN
VLMFPVHEYWLDIGRMADFERAQTDILSLGL
>Mature_350_residues
SNSWKNILIKPEATILDALGVIDNEALQVALVVNSEQKLLGVITDGDIRRGILNNLSLDTPVTEIMNCSPITAEMSSTKE
QLTQLMESKSILAIPLIENGKVVGLETLQRLLETTIYQNPVFIMAGGFGTRLRPLTDSCPKPMLKVGDKPILDILITNFI
KAGFVNFYISTHYMAEQIRSYFGDGSELGVKIHYIHEEAPLGTGGALGLLPDDLPKGLPLIMVNGDVLTKVDFERLLDFH
NEHQADATMCVRKYDYQVPYGVVSGEGNKVTCMVEKPVQHFFVNAGIYVISPCVIDSVPKDYHIDMPTLLDQHMSERENV
LMFPVHEYWLDIGRMADFERAQTDILSLGL

Specific function: Catalyzes The Formation Of Dtdp-Glucose, From Dttp And Glucose 1-Phosphate, As Well As Its Pyrophosphorolysis. [C]

COG id: COG1208

COG function: function code MJ; Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Homo sapiens, GI11761621, Length=228, Percent_Identity=32.8947368421053, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI11761619, Length=228, Percent_Identity=32.8947368421053, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI133931050, Length=235, Percent_Identity=31.063829787234, Blast_Score=121, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6320148, Length=232, Percent_Identity=33.6206896551724, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21355443, Length=227, Percent_Identity=33.920704845815, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24644084, Length=227, Percent_Identity=33.920704845815, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24653912, Length=202, Percent_Identity=28.7128712871287, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.13 [H]

Molecular weight: Translated: 39039; Mature: 38908

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSWKNILIKPEATILDALGVIDNEALQVALVVNSEQKLLGVITDGDIRRGILNNLSLD
CCCCCCEEEECCCHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHCCCCC
TPVTEIMNCSPITAEMSSTKEQLTQLMESKSILAIPLIENGKVVGLETLQRLLETTIYQN
CCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEECHHHHHHHHHHHHHCC
PVFIMAGGFGTRLRPLTDSCPKPMLKVGDKPILDILITNFIKAGFVNFYISTHYMAEQIR
CEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHH
SYFGDGSELGVKIHYIHEEAPLGTGGALGLLPDDLPKGLPLIMVNGDVLTKVDFERLLDF
HHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEHCCHHHHHHH
HNEHQADATMCVRKYDYQVPYGVVSGEGNKVTCMVEKPVQHFFVNAGIYVISPCVIDSVP
HCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCHHHHHHHCCEEEEEHHHHCCCC
KDYHIDMPTLLDQHMSERENVLMFPVHEYWLDIGRMADFERAQTDILSLGL
CCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHCCC
>Mature Secondary Structure 
SNSWKNILIKPEATILDALGVIDNEALQVALVVNSEQKLLGVITDGDIRRGILNNLSLD
CCCCCEEEECCCHHHHHHHHCCCCCCEEEEEEECCCCEEEEEEECCHHHHHHHHCCCCC
TPVTEIMNCSPITAEMSSTKEQLTQLMESKSILAIPLIENGKVVGLETLQRLLETTIYQN
CCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCEECHHHHHHHHHHHHHCC
PVFIMAGGFGTRLRPLTDSCPKPMLKVGDKPILDILITNFIKAGFVNFYISTHYMAEQIR
CEEEEECCCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHH
SYFGDGSELGVKIHYIHEEAPLGTGGALGLLPDDLPKGLPLIMVNGDVLTKVDFERLLDF
HHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCEEEHCCHHHHHHH
HNEHQADATMCVRKYDYQVPYGVVSGEGNKVTCMVEKPVQHFFVNAGIYVISPCVIDSVP
HCCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCHHHHHHHCCEEEEEHHHHCCCC
KDYHIDMPTLLDQHMSERENVLMFPVHEYWLDIGRMADFERAQTDILSLGL
CCCCCCCHHHHHHHHHCCCCEEEEEHHHHHHHHHHHCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8334170 [H]