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The map label for this gene is trkH [H]

Identifier: 157959857

GI number: 157959857

Start: 29446

End: 30888

Strand: Reverse

Name: trkH [H]

Synonym: Spea_0027

Alternate gene names: 157959857

Gene position: 30888-29446 (Counterclockwise)

Preceding gene: 157959858

Following gene: 157959855

Centisome position: 0.6

GC content: 49.06

Gene sequence:

>1443_bases
GTGCTGAACTATCGTCCTCTACTGTTTATTCTGGGAATTTTCCTATCGACGCTGACCGCGTTTATGTTAATTCCCGGAGC
CTTCGCCCTCTATTATGGTGAAGAGACTGTTGGTGCATTCATGATCTCCTCCTTGGCTGCTGGTAGCGCAGCCAGCTTTT
GTATGCATCAAGGTCAGAGCCGTAAACTACATCTCAATATTCGAGATATGTTTCTACTAACCTGCCTCACTTGGCTCATC
GTCAGTCTTTTTGCGGCAATGCCCTTTACCCTGTATCACGGCATCAACTACACCGACGCCTTCTTCGAAACCATGTCGGG
GATCACCACCACGGGGTCTACCGTGTTGTCGGGGCTAGACACCATGGATCACAGCATTCTGATCTGGCGCTCATTACTAC
AATGGCTCGGTGGGATCGGTTTTATCGTGATGGCAGTAGCCGTACTGCCCTTCTTAAATGTTGGTGGTATGCGGCTATTT
AGAACCGAGTCTTCAGACTGGAGCGACAAAACCACCCCCCGTACCCAACACATGGCCAAGAACCTATTTATTGTTTATTG
CCTACTGACATTCTTATGCTTCTTGGCATATCACGGCAGCGGCATGAACTGGTTCCAAGCTATCAACCATGCCATGACAA
CCCTATCTACAGGCGGCTACTCCACTTCAGATCAATCCATGGCAGCATTTTCCAATGAAGCTCACTGGGTCGGCACCACC
TTTATGCTCGCTGGCGGATTGCCGCTGCTTATGTTCGTCTATATGGTGCAGCAACGTTCGGTAAAAGTGTGGAACGACGC
CCAGGTAAAAGGCTTTCTCAAGTTTGTGGCTTTCGTTTCTTGTGCACTCGCCTTATGGCTTTGGAGCAGCAGAGGGATAG
CACCTTTAGATGCGCTGCGCTTGGCCAGCTTTAACGTAGTATCTGTGGTAACAACCACAGGCTATGGCCTTACCGACTAC
ACCGCTTGGGGAGCATTGGCGAATATTGTGTTTCTATTCCTGATGTTTGTCGGTAGCTGTTCGGGGTCAACCTCTGGCGG
CATCAAGATCTTTCGCTTTCAAATTGCCGGCGTGATTATGCGTGAGCAACTTAAGCAGCAATTCCACCCTAACGGTGTGT
TCAAAGAACGCTATAACAACCATATTGTTCGTGGAGATATTGTCCGCTCACTAGTCACTTTCATTCTGCTATTTGTACTG
GTGATAGTGCTGCTATCCATCATTTTGGTGTTAACAGGACTCGATCCCGTCACTAGCTTTACCGGCGCCATTACCGCAGT
CACCAATGTTGGCCCAGGATTAGGTAGCACCATAGGGCCTGCAGGCAACTTCTCATCTCTACCAGATGTTGCAAAATGGG
CATTAGCTATCGGCATGCTACTAGGCCGCCTTGAGATCTTAACCGTCGCAGTCCTTTTCCATCCTAGTTTCTGGAAGTAC
TAG

Upstream 100 bases:

>100_bases
CGTCATCCTCTTCTTAGTAAACAAGAAGTTTATTGGTGAAGTTGAGAAACTGTTCCAACCGAGTGCTTTCTTCTTTTAAA
AAACCTTCAGGAGCGGAATA

Downstream 100 bases:

>100_bases
ACAAGCTTCAAACACAAAAAAGCCGCATTAATTGCGGCTTTTTTGATTGGTGTGCTTATTTAGCTAAACTCACTAGGTGG
TCTGCATAGACCTTCACATC

Product: TrkH family potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MLNYRPLLFILGIFLSTLTAFMLIPGAFALYYGEETVGAFMISSLAAGSAASFCMHQGQSRKLHLNIRDMFLLTCLTWLI
VSLFAAMPFTLYHGINYTDAFFETMSGITTTGSTVLSGLDTMDHSILIWRSLLQWLGGIGFIVMAVAVLPFLNVGGMRLF
RTESSDWSDKTTPRTQHMAKNLFIVYCLLTFLCFLAYHGSGMNWFQAINHAMTTLSTGGYSTSDQSMAAFSNEAHWVGTT
FMLAGGLPLLMFVYMVQQRSVKVWNDAQVKGFLKFVAFVSCALALWLWSSRGIAPLDALRLASFNVVSVVTTTGYGLTDY
TAWGALANIVFLFLMFVGSCSGSTSGGIKIFRFQIAGVIMREQLKQQFHPNGVFKERYNNHIVRGDIVRSLVTFILLFVL
VIVLLSIILVLTGLDPVTSFTGAITAVTNVGPGLGSTIGPAGNFSSLPDVAKWALAIGMLLGRLEILTVAVLFHPSFWKY

Sequences:

>Translated_480_residues
MLNYRPLLFILGIFLSTLTAFMLIPGAFALYYGEETVGAFMISSLAAGSAASFCMHQGQSRKLHLNIRDMFLLTCLTWLI
VSLFAAMPFTLYHGINYTDAFFETMSGITTTGSTVLSGLDTMDHSILIWRSLLQWLGGIGFIVMAVAVLPFLNVGGMRLF
RTESSDWSDKTTPRTQHMAKNLFIVYCLLTFLCFLAYHGSGMNWFQAINHAMTTLSTGGYSTSDQSMAAFSNEAHWVGTT
FMLAGGLPLLMFVYMVQQRSVKVWNDAQVKGFLKFVAFVSCALALWLWSSRGIAPLDALRLASFNVVSVVTTTGYGLTDY
TAWGALANIVFLFLMFVGSCSGSTSGGIKIFRFQIAGVIMREQLKQQFHPNGVFKERYNNHIVRGDIVRSLVTFILLFVL
VIVLLSIILVLTGLDPVTSFTGAITAVTNVGPGLGSTIGPAGNFSSLPDVAKWALAIGMLLGRLEILTVAVLFHPSFWKY
>Mature_480_residues
MLNYRPLLFILGIFLSTLTAFMLIPGAFALYYGEETVGAFMISSLAAGSAASFCMHQGQSRKLHLNIRDMFLLTCLTWLI
VSLFAAMPFTLYHGINYTDAFFETMSGITTTGSTVLSGLDTMDHSILIWRSLLQWLGGIGFIVMAVAVLPFLNVGGMRLF
RTESSDWSDKTTPRTQHMAKNLFIVYCLLTFLCFLAYHGSGMNWFQAINHAMTTLSTGGYSTSDQSMAAFSNEAHWVGTT
FMLAGGLPLLMFVYMVQQRSVKVWNDAQVKGFLKFVAFVSCALALWLWSSRGIAPLDALRLASFNVVSVVTTTGYGLTDY
TAWGALANIVFLFLMFVGSCSGSTSGGIKIFRFQIAGVIMREQLKQQFHPNGVFKERYNNHIVRGDIVRSLVTFILLFVL
VIVLLSIILVLTGLDPVTSFTGAITAVTNVGPGLGSTIGPAGNFSSLPDVAKWALAIGMLLGRLEILTVAVLFHPSFWKY

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=486, Percent_Identity=36.0082304526749, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1787626, Length=466, Percent_Identity=33.6909871244635, Blast_Score=232, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52705; Mature: 52705

Theoretical pI: Translated: 8.93; Mature: 8.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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>Mature Secondary Structure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PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]