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The map label for this gene is yfhC [C]

Identifier: 157826299

GI number: 157826299

Start: 1153755

End: 1154234

Strand: Reverse

Name: yfhC [C]

Synonym: A1C_06440

Alternate gene names: 157826299

Gene position: 1154234-1153755 (Counterclockwise)

Preceding gene: 157826300

Following gene: 157826298

Centisome position: 93.76

GC content: 33.54

Gene sequence:

>480_bases
GTGAATATATTGTTAGATAAAGAAATGAGTTTCAATAACTTTTTCATGGAGCAAGCTTTAAAACAAGCACGGCTCGCTTT
TGATAAAAATGAAGTTCCGGTCGGAGCGGTGATGGTAGAGAGGTTAAATCAAAAAATCGTTATTAATAGTCATAATAATA
CCGAAGAAAAAAACAACGCTCTTTATCATGCTGAAATTATTGCTATTAATGAAGTGTGTAATCTTATATCTTCTAAAAAT
TTAAATGATTATGATATTTACGTTACTTTAGAACCTTGTGCCATGTGTGCAGCGGCTATAGCTCATAGCAGGTTAAAACG
TTTGTTTTACGGTGCTTCTGATTCTAAGCACGGGGCAGTTGAAAGTAATTTACGATATTTTAACAGTAGTGCTTGTTTTC
ATAGACCGGAAATATATAGCGGAATTCTTGCTGAAGATTCTGGGCTATTAATGAAAGAGTTTTTTAGGAGGATACGATAA

Upstream 100 bases:

>100_bases
ATTAGCGATGAGATTGTTTGTGAAATATTGCAGGAATTTCCGGAAGCTGAAATAATTATCCACCAAGATCCTTTTGGAGT
CGAAGAACACGTAAATTATC

Downstream 100 bases:

>100_bases
TCATGGTAGAGCATTGCTTGCGTGGATTATCAAGTATGCTCGATGTCATACCGTGACTTGACCATGGTATCCATAAAAAT
AACTTAAAAATACTAATAAA

Product: cytosine deaminase

Products: uracil; NH3

Alternate protein names: NA

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNILLDKEMSFNNFFMEQALKQARLAFDKNEVPVGAVMVERLNQKIVINSHNNTEEKNNALYHAEIIAINEVCNLISSKN
LNDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGAVESNLRYFNSSACFHRPEIYSGILAEDSGLLMKEFFRRIR

Sequences:

>Translated_159_residues
MNILLDKEMSFNNFFMEQALKQARLAFDKNEVPVGAVMVERLNQKIVINSHNNTEEKNNALYHAEIIAINEVCNLISSKN
LNDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGAVESNLRYFNSSACFHRPEIYSGILAEDSGLLMKEFFRRIR
>Mature_159_residues
MNILLDKEMSFNNFFMEQALKQARLAFDKNEVPVGAVMVERLNQKIVINSHNNTEEKNNALYHAEIIAINEVCNLISSKN
LNDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGAVESNLRYFNSSACFHRPEIYSGILAEDSGLLMKEFFRRIR

Specific function: Mutation In This Protein Makes E.Coli Resistant To The Toxic Proteins Encoded By The Gef Gene Family. [C]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=151, Percent_Identity=30.4635761589404, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI145693172, Length=153, Percent_Identity=39.2156862745098, Blast_Score=115, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17541138, Length=154, Percent_Identity=31.1688311688312, Blast_Score=78, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6322425, Length=154, Percent_Identity=26.6233766233766, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21355527, Length=148, Percent_Identity=33.7837837837838, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: 3.5.4.1

Molecular weight: Translated: 18155; Mature: 18155

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILLDKEMSFNNFFMEQALKQARLAFDKNEVPVGAVMVERLNQKIVINSHNNTEEKNNA
CCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCE
LYHAEIIAINEVCNLISSKNLNDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGAV
EEEHHEEEHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ESNLRYFNSSACFHRPEIYSGILAEDSGLLMKEFFRRIR
HHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MNILLDKEMSFNNFFMEQALKQARLAFDKNEVPVGAVMVERLNQKIVINSHNNTEEKNNA
CCEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECCCCCCCCCCE
LYHAEIIAINEVCNLISSKNLNDYDIYVTLEPCAMCAAAIAHSRLKRLFYGASDSKHGAV
EEEHHEEEHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
ESNLRYFNSSACFHRPEIYSGILAEDSGLLMKEFFRRIR
HHHHHHHCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: cytosine; H2O

Specific reaction: cytosine + H2O = uracil + NH3

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]