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The map label for this gene is cycZ [H]

Identifier: 157826298

GI number: 157826298

Start: 1152854

End: 1153546

Strand: Reverse

Name: cycZ [H]

Synonym: A1C_06435

Alternate gene names: 157826298

Gene position: 1153546-1152854 (Counterclockwise)

Preceding gene: 157826299

Following gene: 157826297

Centisome position: 93.7

GC content: 32.32

Gene sequence:

>693_bases
ATGCTAAAACTATTAACACCTTATTATTTTAATAAATTATCAAAGGTTATAATACATGTGTTAGCTATATCTACTCTTGT
AATGATGATTATAGGTCTTTATTTAGCCCTCATAGTTTCGCCGATAGATTATCAACAAGGTGAGTTTATACGCATTATGT
ATGTTCACGTACCTGCTTCTTGGATGGCACTTGGTATTTATGTGTTCATGGCAGCATGCAGCTTTAGTTATCTAGTATGG
AAAACTACTATCAGCTATTTGTTAGCTGTAGCATCTAGTTACGTTGGGGCTATTTTTACTTTGATTAGCTTAATAACAGG
TGCTTTATGGGGAAAGCCTATATGGGGTACATGGTGGGCTTGGGATGCAAGGCTTACTTCTATGCTCATATTATTTTTGT
TATATCTAAGCTATATTATCATAGTGAATAGTGCGGATAATATAAGAAAAGCACAAAATCCTGCTTCTATTATTGCTCTT
ATCGGACTGATCAATATACCGATAGTAAAATTTTCGGTAAATATTTGGTATAGCCTACATCAGCCTGCTAGTGTTTTAAG
GCTAGGGAGTCCAACTATTCACTCTTCAATGCTAAAGCCTTTAATTATCATGTTTATCAGTTTTATATTATATTTTCTAT
TAGTATTACTTTTAAGAACTTCTATATTAATCGATAAAATCAAAAACAGATAA

Upstream 100 bases:

>100_bases
TTTTTAGTTAGATCCCGCGATCAAGTTGCGGGATGACAAATGAAAAATCTATCCATACACGCAAGCCTTCTGCAAGAATG
ACATAAAGAAGTAAGAAAAT

Downstream 100 bases:

>100_bases
CAAAATGACTTATGTTGTAACCGATGAATGTGTAAAATGTAAATATACCGATTGTGTTGAAGTATGTCCTGTAGATTGTT
TCTACGAAGGTGAATTTATG

Product: Heme exporter protein C

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 230; Mature: 230

Protein sequence:

>230_residues
MLKLLTPYYFNKLSKVIIHVLAISTLVMMIIGLYLALIVSPIDYQQGEFIRIMYVHVPASWMALGIYVFMAACSFSYLVW
KTTISYLLAVASSYVGAIFTLISLITGALWGKPIWGTWWAWDARLTSMLILFLLYLSYIIIVNSADNIRKAQNPASIIAL
IGLINIPIVKFSVNIWYSLHQPASVLRLGSPTIHSSMLKPLIIMFISFILYFLLVLLLRTSILIDKIKNR

Sequences:

>Translated_230_residues
MLKLLTPYYFNKLSKVIIHVLAISTLVMMIIGLYLALIVSPIDYQQGEFIRIMYVHVPASWMALGIYVFMAACSFSYLVW
KTTISYLLAVASSYVGAIFTLISLITGALWGKPIWGTWWAWDARLTSMLILFLLYLSYIIIVNSADNIRKAQNPASIIAL
IGLINIPIVKFSVNIWYSLHQPASVLRLGSPTIHSSMLKPLIIMFISFILYFLLVLLLRTSILIDKIKNR
>Mature_230_residues
MLKLLTPYYFNKLSKVIIHVLAISTLVMMIIGLYLALIVSPIDYQQGEFIRIMYVHVPASWMALGIYVFMAACSFSYLVW
KTTISYLLAVASSYVGAIFTLISLITGALWGKPIWGTWWAWDARLTSMLILFLLYLSYIIIVNSADNIRKAQNPASIIAL
IGLINIPIVKFSVNIWYSLHQPASVLRLGSPTIHSSMLKPLIIMFISFILYFLLVLLLRTSILIDKIKNR

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=228, Percent_Identity=39.0350877192982, Blast_Score=166, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 26097; Mature: 26097

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLLTPYYFNKLSKVIIHVLAISTLVMMIIGLYLALIVSPIDYQQGEFIRIMYVHVPAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHH
WMALGIYVFMAACSFSYLVWKTTISYLLAVASSYVGAIFTLISLITGALWGKPIWGTWWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
WDARLTSMLILFLLYLSYIIIVNSADNIRKAQNPASIIALIGLINIPIVKFSVNIWYSLH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHCCHHEEEEEEEEECC
QPASVLRLGSPTIHSSMLKPLIIMFISFILYFLLVLLLRTSILIDKIKNR
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKLLTPYYFNKLSKVIIHVLAISTLVMMIIGLYLALIVSPIDYQQGEFIRIMYVHVPAS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCHH
WMALGIYVFMAACSFSYLVWKTTISYLLAVASSYVGAIFTLISLITGALWGKPIWGTWWA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
WDARLTSMLILFLLYLSYIIIVNSADNIRKAQNPASIIALIGLINIPIVKFSVNIWYSLH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCHHHHHHHHHHHHCCHHEEEEEEEEECC
QPASVLRLGSPTIHSSMLKPLIIMFISFILYFLLVLLLRTSILIDKIKNR
CCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]