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The map label for this gene is clpX [H]

Identifier: 157826114

GI number: 157826114

Start: 964545

End: 965822

Strand: Reverse

Name: clpX [H]

Synonym: A1C_05445

Alternate gene names: 157826114

Gene position: 965822-964545 (Counterclockwise)

Preceding gene: 157826115

Following gene: 157826111

Centisome position: 78.45

GC content: 34.66

Gene sequence:

>1278_bases
ATGGTAGTAGAAGCTGATAAAAAAGAATTGATTTGTTCGTTTTGTAGTAAAAAACAACATGAAGTAAAAAAACTGATAGC
AGGTCCTGCAGTATTTATTTGTGATGAATGTATAGATTTATGTACGGATATTATGAAAGAAGAAAGTAGAGTTGCGTTAA
AGCAAATTACTTCTTCAATTCCAACACCGCAAAAAATATGTGCAATTCTAAACGATTACGTAGTTGGGCAAGACCAAGCT
AAAAAGATTTTAGCAGTAGCGGTTTATAACCATTATAAGCGACTTGAATATGTACAATCCGGCAATAATGACGTTGAGCT
TAATAAGTCAAATATTTTATTGATTGGTCCTACCGGTTCAGGCAAAACTTTACTTGCTCAAACGCTTGCTAAAATTCTAG
ACGTACCTTTTACTATGGCGGATGCTACTTCTTTAACGGAAGCCGGTTATGTTGGTGAAGATGTTGAGAATATATTACTA
CGCTTATTGATAGCAGCTGAGTTTAATATAGCAAAAGCACAAAAAGGTATAATTTATATTGACGAAGTTGATAAAATTGC
ACGTAAATCAGAGAATCCTTCTATTACACGTGATGTATCGGGCGAAGGAGTACAGCAGGCATTACTTAAAATTATGGAAG
GCACAGTTGCTTCTGTGCCTCCTCAAGGCGGTAGGAAACACCCGCAACAAGATTTCGTACAGTTAGATACTTCAAATATC
TTATTTATTTGTGGTGGTGCTTTTATGGGGGTTGATAGCATTATAACCTCAAGAACTAATCATAGTTCTATAGGCTTTGC
AGCTAACGTAAATATAGATAAAGAGAAAAATAATAGTGAGATTCTTAAATCCCTAGAGATTGAGGATTTAACTAAATTCG
GTTTAATCCCTGAATTTATCGGTAGGTTACCCATCGTTACTACTTTAGATGAGTTAGACAAAGAAGCTTTAATTACAATT
CTCACTAAGCCTAAGAACGCCATAGTAAAGCAATATAAGAAACAATTTGAGCTTGATGATACTGAGCTTGTAATTGAAAA
TTCTGCACTAGAAGCTATTGCTGAAAAAGCTTTGGCTAAAAAGACTGGAGCAAGAGGGCTTCGTTCAATACTTGAGCATC
TTTTGCTTGATAGTATGTATAAAGTTGCTGAGCTAAAAAAACAGCGTGTTACTATTACAAAAGAGGTAGTTAACGGCTTA
GTAGAACCGATAATGACATCTCTTATTTCTACAAAATCAAACAAAAAACAATCGATGATTGAAGATATACCAGCGTAA

Upstream 100 bases:

>100_bases
TAAAGATTATTATATGTATGGTAGGGTTGTATGAATTGTACTGTCATCCCGTGGTCAAGACACGTGATGACAGTGAGTAT
AAACATAAAAAAGAAAGTTA

Downstream 100 bases:

>100_bases
ATATTGTTTCCTCGCTATGTAATTCTTACGGACTTGCCTGCGTGTATCGAAAAACGCATTAGGTGTCATCCCGTGGCTTG
ACCACGGTATCCAGTTAAAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MVVEADKKELICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEESRVALKQITSSIPTPQKICAILNDYVVGQDQA
KKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGSGKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILL
RLLIAAEFNIAKAQKGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNI
LFICGGAFMGVDSIITSRTNHSSIGFAANVNIDKEKNNSEILKSLEIEDLTKFGLIPEFIGRLPIVTTLDELDKEALITI
LTKPKNAIVKQYKKQFELDDTELVIENSALEAIAEKALAKKTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVNGL
VEPIMTSLISTKSNKKQSMIEDIPA

Sequences:

>Translated_425_residues
MVVEADKKELICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEESRVALKQITSSIPTPQKICAILNDYVVGQDQA
KKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGSGKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILL
RLLIAAEFNIAKAQKGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNI
LFICGGAFMGVDSIITSRTNHSSIGFAANVNIDKEKNNSEILKSLEIEDLTKFGLIPEFIGRLPIVTTLDELDKEALITI
LTKPKNAIVKQYKKQFELDDTELVIENSALEAIAEKALAKKTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVNGL
VEPIMTSLISTKSNKKQSMIEDIPA
>Mature_425_residues
MVVEADKKELICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEESRVALKQITSSIPTPQKICAILNDYVVGQDQA
KKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGSGKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILL
RLLIAAEFNIAKAQKGIIYIDEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNI
LFICGGAFMGVDSIITSRTNHSSIGFAANVNIDKEKNNSEILKSLEIEDLTKFGLIPEFIGRLPIVTTLDELDKEALITI
LTKPKNAIVKQYKKQFELDDTELVIENSALEAIAEKALAKKTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVNGL
VEPIMTSLISTKSNKKQSMIEDIPA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=332, Percent_Identity=49.3975903614458, Blast_Score=309, Evalue=3e-84,
Organism=Escherichia coli, GI1786642, Length=402, Percent_Identity=63.681592039801, Blast_Score=525, Evalue=1e-150,
Organism=Escherichia coli, GI1790366, Length=105, Percent_Identity=41.9047619047619, Blast_Score=94, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=308, Percent_Identity=46.1038961038961, Blast_Score=275, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=308, Percent_Identity=46.1038961038961, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=389, Percent_Identity=38.560411311054, Blast_Score=241, Evalue=5e-64,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=40.5622489959839, Blast_Score=168, Evalue=6e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=456, Percent_Identity=37.9385964912281, Blast_Score=267, Evalue=2e-72,
Organism=Drosophila melanogaster, GI24648291, Length=320, Percent_Identity=45, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=45, Blast_Score=281, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46699; Mature: 46699

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVEADKKELICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEESRVALKQITSSI
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PTPQKICAILNDYVVGQDQAKKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGS
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCC
GKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILLRLLIAAEFNIAKAQKGIIYI
CHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEEE
DEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNI
EHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHEECCCCE
LFICGGAFMGVDSIITSRTNHSSIGFAANVNIDKEKNNSEILKSLEIEDLTKFGLIPEFI
EEEECCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHCCCHHHH
GRLPIVTTLDELDKEALITILTKPKNAIVKQYKKQFELDDTELVIENSALEAIAEKALAK
CCCCHHHHHHHHCHHHEEHEEECCHHHHHHHHHHHCCCCCHHEEEEHHHHHHHHHHHHHH
KTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVNGLVEPIMTSLISTKSNKKQSMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EDIPA
HHCCC
>Mature Secondary Structure
MVVEADKKELICSFCSKKQHEVKKLIAGPAVFICDECIDLCTDIMKEESRVALKQITSSI
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PTPQKICAILNDYVVGQDQAKKILAVAVYNHYKRLEYVQSGNNDVELNKSNILLIGPTGS
CCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEEEEECCCC
GKTLLAQTLAKILDVPFTMADATSLTEAGYVGEDVENILLRLLIAAEFNIAKAQKGIIYI
CHHHHHHHHHHHHCCCCCHHCHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHCCCEEEE
DEVDKIARKSENPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQDFVQLDTSNI
EHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHHEECCCCE
LFICGGAFMGVDSIITSRTNHSSIGFAANVNIDKEKNNSEILKSLEIEDLTKFGLIPEFI
EEEECCHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHCCCHHHH
GRLPIVTTLDELDKEALITILTKPKNAIVKQYKKQFELDDTELVIENSALEAIAEKALAK
CCCCHHHHHHHHCHHHEEHEEECCHHHHHHHHHHHCCCCCHHEEEEHHHHHHHHHHHHHH
KTGARGLRSILEHLLLDSMYKVAELKKQRVTITKEVVNGLVEPIMTSLISTKSNKKQSMI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
EDIPA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA