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The map label for this gene is ycfH [C]

Identifier: 157826101

GI number: 157826101

Start: 947655

End: 948404

Strand: Reverse

Name: ycfH [C]

Synonym: A1C_05325

Alternate gene names: 157826101

Gene position: 948404-947655 (Counterclockwise)

Preceding gene: 157826102

Following gene: 157826100

Centisome position: 77.04

GC content: 35.2

Gene sequence:

>750_bases
GTGCTTTTAGATTCTGTCATTCAAAGAGCATTAGAAAATAATGTGCAGTATATGCAAACTATCTGTACTAAGCTTGAAGA
TTTACAAATTGTGTTAGAAATAGCCGAAAAATATGACAATATTTTTGCAAGCGTTGGTGTGCATCCGTGTGAGGTTAATG
AAAGCAGTATGCTAATTACGGATTCAGAAATAATAGAGATTACCAACCATCCGAAAATGATTGGCATCGGTGAAACGGGG
CTTGATTATTATCATCAGCTTTACGATAAAACACTCCAAAAAGATTCGTTTGTAGCACATATACATGCGGCGTCTAGTAC
ACGTCTGCCTGTTATTGTTCATACAAGAGCAGCAGATGAAGACACTATTGACATTTTAACATCAGAAATGCGTAACAGCA
AATTTCCAGGTTTAATACACTGCTTTACCTCTTCAAAAAAATTAGCAGAAAAAATGCTAGATATCGGTTTATATATTTCA
ATGTCAGGGATTATAACTTTCAAGAATGCAACCGATTTGCAGGAAATAGTTAAATATATACCGCTTGATAGGTTATTAAT
CGAAACTGACTCACCTTACCTAGCACCTACCCCTATGCGTGGCAAACAAAACGAACCGGCTTTTGTTAGATATGTCGCAG
AGAAAGTCGCTGAACTCAAAAATATCACCTCAAAAGAAGTAGCAAATGTTACTACTCAAAACTTCAAAACATTATTTTCC
AAATTTGAAAAGCATACTCGTTTAATTTGA

Upstream 100 bases:

>100_bases
CTTATCATCCCGCGATCTCGTAGCGGGATCCAGTAAAAATATTAAAACAACTAATACTAGTTGTTTTTTGGATACCATGG
TCAAACCACGGTATGACACG

Downstream 100 bases:

>100_bases
AACATTGGCTACAAAGTCTCTTATTAATAATCCTCACGTACTAGTGTACGCTGCTCAAGATTGATAATTTAAAGTTGAAA
TTTTTAAAATAACTATTTAT

Product: putative deoxyribonuclease, hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 249; Mature: 249

Protein sequence:

>249_residues
MLLDSVIQRALENNVQYMQTICTKLEDLQIVLEIAEKYDNIFASVGVHPCEVNESSMLITDSEIIEITNHPKMIGIGETG
LDYYHQLYDKTLQKDSFVAHIHAASSTRLPVIVHTRAADEDTIDILTSEMRNSKFPGLIHCFTSSKKLAEKMLDIGLYIS
MSGIITFKNATDLQEIVKYIPLDRLLIETDSPYLAPTPMRGKQNEPAFVRYVAEKVAELKNITSKEVANVTTQNFKTLFS
KFEKHTRLI

Sequences:

>Translated_249_residues
MLLDSVIQRALENNVQYMQTICTKLEDLQIVLEIAEKYDNIFASVGVHPCEVNESSMLITDSEIIEITNHPKMIGIGETG
LDYYHQLYDKTLQKDSFVAHIHAASSTRLPVIVHTRAADEDTIDILTSEMRNSKFPGLIHCFTSSKKLAEKMLDIGLYIS
MSGIITFKNATDLQEIVKYIPLDRLLIETDSPYLAPTPMRGKQNEPAFVRYVAEKVAELKNITSKEVANVTTQNFKTLFS
KFEKHTRLI
>Mature_249_residues
MLLDSVIQRALENNVQYMQTICTKLEDLQIVLEIAEKYDNIFASVGVHPCEVNESSMLITDSEIIEITNHPKMIGIGETG
LDYYHQLYDKTLQKDSFVAHIHAASSTRLPVIVHTRAADEDTIDILTSEMRNSKFPGLIHCFTSSKKLAEKMLDIGLYIS
MSGIITFKNATDLQEIVKYIPLDRLLIETDSPYLAPTPMRGKQNEPAFVRYVAEKVAELKNITSKEVANVTTQNFKTLFS
KFEKHTRLI

Specific function: Unknown

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349730, Length=252, Percent_Identity=29.7619047619048, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI14042943, Length=260, Percent_Identity=27.3076923076923, Blast_Score=97, Evalue=9e-21,
Organism=Homo sapiens, GI110349734, Length=252, Percent_Identity=29.7619047619048, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI226061853, Length=257, Percent_Identity=29.1828793774319, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI225903439, Length=243, Percent_Identity=26.7489711934156, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI226061614, Length=241, Percent_Identity=28.6307053941909, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI225903424, Length=216, Percent_Identity=27.7777777777778, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI226061595, Length=211, Percent_Identity=26.0663507109005, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1787342, Length=237, Percent_Identity=43.0379746835443, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI48994985, Length=243, Percent_Identity=30.8641975308642, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87082439, Length=242, Percent_Identity=27.6859504132231, Blast_Score=107, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17559024, Length=265, Percent_Identity=27.9245283018868, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17565396, Length=225, Percent_Identity=29.3333333333333, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17543026, Length=181, Percent_Identity=31.4917127071823, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71980746, Length=246, Percent_Identity=27.2357723577236, Blast_Score=80, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24648690, Length=274, Percent_Identity=27.7372262773723, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI221330018, Length=274, Percent_Identity=27.3722627737226, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24586117, Length=274, Percent_Identity=27.3722627737226, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 28228; Mature: 28228

Theoretical pI: Translated: 5.86; Mature: 5.86

Prosite motif: PS01090 TATD_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLDSVIQRALENNVQYMQTICTKLEDLQIVLEIAEKYDNIFASVGVHPCEVNESSMLIT
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEE
DSEIIEITNHPKMIGIGETGLDYYHQLYDKTLQKDSFVAHIHAASSTRLPVIVHTRAADE
CCCEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCCC
DTIDILTSEMRNSKFPGLIHCFTSSKKLAEKMLDIGLYISMSGIITFKNATDLQEIVKYI
HHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHEEEEECEEEECCCCCHHHHHHHC
PLDRLLIETDSPYLAPTPMRGKQNEPAFVRYVAEKVAELKNITSKEVANVTTQNFKTLFS
CCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KFEKHTRLI
HHHHHHCCC
>Mature Secondary Structure
MLLDSVIQRALENNVQYMQTICTKLEDLQIVLEIAEKYDNIFASVGVHPCEVNESSMLIT
CCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCEEEEE
DSEIIEITNHPKMIGIGETGLDYYHQLYDKTLQKDSFVAHIHAASSTRLPVIVHTRAADE
CCCEEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEECCCCC
DTIDILTSEMRNSKFPGLIHCFTSSKKLAEKMLDIGLYISMSGIITFKNATDLQEIVKYI
HHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHEEEEECEEEECCCCCHHHHHHHC
PLDRLLIETDSPYLAPTPMRGKQNEPAFVRYVAEKVAELKNITSKEVANVTTQNFKTLFS
CCCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
KFEKHTRLI
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]