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The map label for this gene is glmU [H]

Identifier: 157825897

GI number: 157825897

Start: 752952

End: 753698

Strand: Direct

Name: glmU [H]

Synonym: A1C_04180

Alternate gene names: 157825897

Gene position: 752952-753698 (Clockwise)

Preceding gene: 157825896

Following gene: 157825898

Centisome position: 61.16

GC content: 29.99

Gene sequence:

>747_bases
ATGACTTATAGCGATGCAAATTATCAAATAATTATTTTAGCAGCCGGTAAAGGGACTAGAATGGAGTCCGATTTACCAAA
AGTAATGCATAAAGTCGGCGGAGTTCCAATGCTTGAAACGGTATTAAAGAATTCGCTTAACGTCACAAATGATGTAATTA
TAGTTTATTCAGAAGCACTTAAAAAACATTTAATGCCCTATGAAAATATGTGTCGTTTTGTACTGCAAGAAGAACCTAAA
GGCACAGCTCATGCTACTTATGCAGTAATAGATTTAATTGATAAAAATAAAACAATATTAGTTTTATATGGTGATCATCC
TCTTATTACTCCAAAACTTATGCATGAATTAATAGATTATTTAGGCCTTACTAATTCTGCATTAGTTACTTTAAGCTTTG
AGAGAGCAAATCCGGCTCAATATGGAAGAATAGCTACTGATAGACATGGTGAATTTTTAGAGATAATTGAACATAAAAAC
GCAAGCGAAGAAGAAAAAAACATCACACTTTGTAATTCAGGTATTATGGCTTTCAGTAGCGGAATTTTAAATAAGTACTT
ACCTTTATTTGCTACTAATACTAACGGTAATAAGGAAATTTATTTAACTGAAATAGTAAAAATATGTAAAAATTACGGTG
AAAAGGTTTCATATTTATTATCTACTGATAATGATTTAATTGTTGGTGTTAATACTCAACATGAGCTAGAAGAAGCTAAT
AATATTTTTTCTAAGAATAAGTCTTAG

Upstream 100 bases:

>100_bases
TAAAGCTTGTAGAAGCTTTAGAAGAAAGCGACGATGTACAAAGAGTTTTCAGTAATTATGAATTCTCCGATGATGTTTAC
GAAATAATACAAGGAGAAGA

Downstream 100 bases:

>100_bases
CGTTGCGGTATATGGATCGTTTTTATCGTCACTGCGAGGAAAAACTGTAAGTTTTGACTAAACAATCTCAGGATTTGTTA
TTATTGCCTGAGATTGCAGC

Product: UDP-N-acetylglucosamine pyrophosphorylase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTYSDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEALKKHLMPYENMCRFVLQEEPK
GTAHATYAVIDLIDKNKTILVLYGDHPLITPKLMHELIDYLGLTNSALVTLSFERANPAQYGRIATDRHGEFLEIIEHKN
ASEEEKNITLCNSGIMAFSSGILNKYLPLFATNTNGNKEIYLTEIVKICKNYGEKVSYLLSTDNDLIVGVNTQHELEEAN
NIFSKNKS

Sequences:

>Translated_248_residues
MTYSDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEALKKHLMPYENMCRFVLQEEPK
GTAHATYAVIDLIDKNKTILVLYGDHPLITPKLMHELIDYLGLTNSALVTLSFERANPAQYGRIATDRHGEFLEIIEHKN
ASEEEKNITLCNSGIMAFSSGILNKYLPLFATNTNGNKEIYLTEIVKICKNYGEKVSYLLSTDNDLIVGVNTQHELEEAN
NIFSKNKS
>Mature_247_residues
TYSDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEALKKHLMPYENMCRFVLQEEPKG
TAHATYAVIDLIDKNKTILVLYGDHPLITPKLMHELIDYLGLTNSALVTLSFERANPAQYGRIATDRHGEFLEIIEHKNA
SEEEKNITLCNSGIMAFSSGILNKYLPLFATNTNGNKEIYLTEIVKICKNYGEKVSYLLSTDNDLIVGVNTQHELEEANN
IFSKNKS

Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]

COG id: COG1207

COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]

Homologues:

Organism=Escherichia coli, GI1790168, Length=243, Percent_Identity=32.5102880658436, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005882
- InterPro:   IPR005835
- InterPro:   IPR011004 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.23; =2.3.1.157 [H]

Molecular weight: Translated: 27785; Mature: 27654

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYSDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEAL
CCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEHHHH
KKHLMPYENMCRFVLQEEPKGTAHATYAVIDLIDKNKTILVLYGDHPLITPKLMHELIDY
HHHCCCHHHHHHHHHHCCCCCCHHHHEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHH
LGLTNSALVTLSFERANPAQYGRIATDRHGEFLEIIEHKNASEEEKNITLCNSGIMAFSS
HCCCCCEEEEEEECCCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCHHHHHH
GILNKYLPLFATNTNGNKEIYLTEIVKICKNYGEKVSYLLSTDNDLIVGVNTQHELEEAN
HHHHHCCCEEEECCCCCCEEEHHHHHHHHHHHCHHEEEEEECCCCEEEEECCHHHHHHHH
NIFSKNKS
HHHCCCCC
>Mature Secondary Structure 
TYSDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEAL
CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEHHHH
KKHLMPYENMCRFVLQEEPKGTAHATYAVIDLIDKNKTILVLYGDHPLITPKLMHELIDY
HHHCCCHHHHHHHHHHCCCCCCHHHHEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHH
LGLTNSALVTLSFERANPAQYGRIATDRHGEFLEIIEHKNASEEEKNITLCNSGIMAFSS
HCCCCCEEEEEEECCCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCHHHHHH
GILNKYLPLFATNTNGNKEIYLTEIVKICKNYGEKVSYLLSTDNDLIVGVNTQHELEEAN
HHHHHCCCEEEECCCCCCEEEHHHHHHHHHHHCHHEEEEEECCCCEEEEECCHHHHHHHH
NIFSKNKS
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA