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The map label for this gene is yggW [H]

Identifier: 157825359

GI number: 157825359

Start: 235282

End: 236463

Strand: Direct

Name: yggW [H]

Synonym: A1C_01265

Alternate gene names: 157825359

Gene position: 235282-236463 (Clockwise)

Preceding gene: 157825358

Following gene: 157825373

Centisome position: 19.11

GC content: 31.56

Gene sequence:

>1182_bases
TTGCCTAAATTCTTTAAAAATATGAAAGTTATGGCAGATGATTTAAGCATTTATATTCATTGGCCTTTTTGTTTATCAAA
ATGTCCGTATTGTGATTTTAATTCTCATGTGGCTAGCACTATAGATCATAATCAATGGATTAAATCGTATGAAACCGAAA
TTGAGTATTTTAAGAATATTATTCAAAATAAATATATAAAATCCATTTTTTTTGGTGGCGGAACTCCTTCATTAATGAAT
CCCGTATTAGTTGAATTGATAATCAATAAAATCAATAATCTAGCAATTCTTGATAATCGAACTGAAATAACTCTAGAAAC
CAATCCCACATCATTTGAAACTGAAAAATTTAAAGCGTTCAAATCTGCCGGAATTAACCGTGTGTCCATTGGAGTACAAT
CCTTAAAAGAAGACGATTTAAAAAAATTAGGCAGAACTCATGATGCTTTGCAAGCCATCAAAACAATTGAGCAGGCAAAT
GGGATTTTTCCAAGAGTTTCATTCGATTTAATATATGCACGTAGCGGTCAAAAATTAAAAGACTGGCAAGAAGAATTAAA
GCAAGCTATGCAACTCGCAAATGGGCATATCTCTCTTTATCAATTGACTATCGAAAAAGGTACACCTTTTTATAAATTAT
TTAATGAGGGTAATCTGATTGTGCCGCATTCAGATGCGGCAGCTGAAATGTACGAATGGACAAATCATTATCTAGCATCT
AAAAAATATTTTAGATATGAGATATCTAATTATGCTCTAGCAAATCAGAAATGTTTGCATAATTTGACTTATTGGCATTA
TAATAGTTGCTTAGGTATAGGTCCCGGGGCTCATAGTAGAATCATTGAACCGTCAGGTTCGGTAGCGGCAATTATGATGT
GGCACAAGCCAGAAAAATGGTTAGACTCAGTTAAAACAAAAAATGTCGGTATTCAAACTAACGCTAAGCTAACACATCAA
GAAATAATCGAAGAGATTTTAATGATGGGTTTACGTCTTAGCAAAGGCATAAATATTTCTACATTAGAGCAGAAAATAAA
CGCAAAATTAATGGATATTTTAGACATGAATAACCTTAAACATTATCAAGCGTTAGATTTAATTAAACTAGATAAAAATA
TCTATCTTACCGACAAAGGTTTAATGCTACATAGTTACATAGTACCTAGATTAATTATATGA

Upstream 100 bases:

>100_bases
ATGATTATAGCAAAAAATTTAATCAAAGCCGGTTTAAAAACTGAATTAATAATTGCATTAATCGGATTAAAAAAAGAAGA
GATTGAGAAATTAGAGCAAA

Downstream 100 bases:

>100_bases
AAATTATTCAAGCAATTTTAAAGTTTATAATTATTTTTCTAGATTGCCACGTTGCTTTGCACATCGTCAGGCATTGCACA
CGACGTTTTTATATGATTTC

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MPKFFKNMKVMADDLSIYIHWPFCLSKCPYCDFNSHVASTIDHNQWIKSYETEIEYFKNIIQNKYIKSIFFGGGTPSLMN
PVLVELIINKINNLAILDNRTEITLETNPTSFETEKFKAFKSAGINRVSIGVQSLKEDDLKKLGRTHDALQAIKTIEQAN
GIFPRVSFDLIYARSGQKLKDWQEELKQAMQLANGHISLYQLTIEKGTPFYKLFNEGNLIVPHSDAAAEMYEWTNHYLAS
KKYFRYEISNYALANQKCLHNLTYWHYNSCLGIGPGAHSRIIEPSGSVAAIMMWHKPEKWLDSVKTKNVGIQTNAKLTHQ
EIIEEILMMGLRLSKGINISTLEQKINAKLMDILDMNNLKHYQALDLIKLDKNIYLTDKGLMLHSYIVPRLII

Sequences:

>Translated_393_residues
MPKFFKNMKVMADDLSIYIHWPFCLSKCPYCDFNSHVASTIDHNQWIKSYETEIEYFKNIIQNKYIKSIFFGGGTPSLMN
PVLVELIINKINNLAILDNRTEITLETNPTSFETEKFKAFKSAGINRVSIGVQSLKEDDLKKLGRTHDALQAIKTIEQAN
GIFPRVSFDLIYARSGQKLKDWQEELKQAMQLANGHISLYQLTIEKGTPFYKLFNEGNLIVPHSDAAAEMYEWTNHYLAS
KKYFRYEISNYALANQKCLHNLTYWHYNSCLGIGPGAHSRIIEPSGSVAAIMMWHKPEKWLDSVKTKNVGIQTNAKLTHQ
EIIEEILMMGLRLSKGINISTLEQKINAKLMDILDMNNLKHYQALDLIKLDKNIYLTDKGLMLHSYIVPRLII
>Mature_392_residues
PKFFKNMKVMADDLSIYIHWPFCLSKCPYCDFNSHVASTIDHNQWIKSYETEIEYFKNIIQNKYIKSIFFGGGTPSLMNP
VLVELIINKINNLAILDNRTEITLETNPTSFETEKFKAFKSAGINRVSIGVQSLKEDDLKKLGRTHDALQAIKTIEQANG
IFPRVSFDLIYARSGQKLKDWQEELKQAMQLANGHISLYQLTIEKGTPFYKLFNEGNLIVPHSDAAAEMYEWTNHYLASK
KYFRYEISNYALANQKCLHNLTYWHYNSCLGIGPGAHSRIIEPSGSVAAIMMWHKPEKWLDSVKTKNVGIQTNAKLTHQE
IIEEILMMGLRLSKGINISTLEQKINAKLMDILDMNNLKHYQALDLIKLDKNIYLTDKGLMLHSYIVPRLII

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=294, Percent_Identity=36.734693877551, Blast_Score=228, Evalue=1e-59,
Organism=Escherichia coli, GI1789325, Length=289, Percent_Identity=35.9861591695502, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI87082341, Length=189, Percent_Identity=24.8677248677249, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 45219; Mature: 45088

Theoretical pI: Translated: 8.78; Mature: 8.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKFFKNMKVMADDLSIYIHWPFCLSKCPYCDFNSHVASTIDHNQWIKSYETEIEYFKNI
CCCHHHHHHEEECCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IQNKYIKSIFFGGGTPSLMNPVLVELIINKINNLAILDNRTEITLETNPTSFETEKFKAF
HHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCCHHHHHHH
KSAGINRVSIGVQSLKEDDLKKLGRTHDALQAIKTIEQANGIFPRVSFDLIYARSGQKLK
HHCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHH
DWQEELKQAMQLANGHISLYQLTIEKGTPFYKLFNEGNLIVPHSDAAAEMYEWTNHYLAS
HHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHC
KKYFRYEISNYALANQKCLHNLTYWHYNSCLGIGPGAHSRIIEPSGSVAAIMMWHKPEKW
CCEEEEEECCHHHHHHHHHHHCCCEEECCEEECCCCCCCCEECCCCCEEEEEEECCCHHH
LDSVKTKNVGIQTNAKLTHQEIIEEILMMGLRLSKGINISTLEQKINAKLMDILDMNNLK
HHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
HYQALDLIKLDKNIYLTDKGLMLHSYIVPRLII
HHHHHHEEEECCEEEEECCCCCHHHHHHHHHCC
>Mature Secondary Structure 
PKFFKNMKVMADDLSIYIHWPFCLSKCPYCDFNSHVASTIDHNQWIKSYETEIEYFKNI
CCHHHHHHEEECCEEEEEECCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
IQNKYIKSIFFGGGTPSLMNPVLVELIINKINNLAILDNRTEITLETNPTSFETEKFKAF
HHHHHHHHHEECCCCHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCCCCHHHHHHH
KSAGINRVSIGVQSLKEDDLKKLGRTHDALQAIKTIEQANGIFPRVSFDLIYARSGQKLK
HHCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCHHH
DWQEELKQAMQLANGHISLYQLTIEKGTPFYKLFNEGNLIVPHSDAAAEMYEWTNHYLAS
HHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEECCCCEEEECCCHHHHHHHHHHHHHHC
KKYFRYEISNYALANQKCLHNLTYWHYNSCLGIGPGAHSRIIEPSGSVAAIMMWHKPEKW
CCEEEEEECCHHHHHHHHHHHCCCEEECCEEECCCCCCCCEECCCCCEEEEEEECCCHHH
LDSVKTKNVGIQTNAKLTHQEIIEEILMMGLRLSKGINISTLEQKINAKLMDILDMNNLK
HHHHHHCCCCEECCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCC
HYQALDLIKLDKNIYLTDKGLMLHSYIVPRLII
HHHHHHEEEECCEEEEECCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]