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The map label for this gene is pntB [H]

Identifier: 157825234

GI number: 157825234

Start: 94698

End: 96095

Strand: Reverse

Name: pntB [H]

Synonym: A1C_00565

Alternate gene names: 157825234

Gene position: 96095-94698 (Counterclockwise)

Preceding gene: 157825235

Following gene: 157825233

Centisome position: 7.81

GC content: 36.41

Gene sequence:

>1398_bases
ATGTCCCTACAAATTATCCAGTTATTATACTTAGTTGCGGCTGTTTGCTTTATTCTATCGCTCAAATTCTTATCCTCACA
GAAACAAGCACGTTTAGGTACTACCATAGGTACCTTGGGAATGGTAATAGCAGTCGGCGTTACTTTTTTTCTTCCGGATT
TTACTCATAAATTACCGATTATAGCAACCATATTGTTAGGCGCTATAATCGGAAGGATTATTGCACTTAAAATCTCCATG
ACGGCAATACCTCAATTAGTAGCAGGTTTTCACTCTTTTGTCGGTCTTGCTGCGGTATTTGTAGCTTACTCTACGATACT
TGCTCCTGAAAATTTTTCTATAGGAATAGCAGGAAGTTTAACGATTAATTCATTAATAGAAATATCAGTAGGCGTCTCTA
TTGGTGCTTTAACTTTTAGCGGTTCGGTTATAGCTTTTCTAAAACTACAAGGATTAATGAAAAGTAGCCCGTTAAAATTC
TACGGTCAGCAATATATATGCTTATTAACGGCAATAATATTAGTTATTCTCGTAATATCTTTTATTCGTTCAGAAAATAT
ATTTTTATTTAATCTAATAGTCTTTTTATCGCTGTTAATCGGAGTATTACTAATAATACCGGTAGGTGGTGCAGATATGC
CCGTTATATTATCAATGCTAAACTCTTATTCAGGTTTTGCGGCAGCAGGTATAGGCTTTACGCTTAGCAATAGCCTACTT
ATTATTACCGGAGCATTAGTTGGTAGTAGCGGAGCTATACTTAGCCATATAATGTGCAAGGCTATGAATCGCTCATTAAT
CAAGGTTATTTTTGGAGCATTTTTACCTACACCTACCGGACTTCACAATGATATAGACGACGATAAAATAGTAAAAACAA
GCTGCCCTGAAGATGCGGCACATTTACTACTTAATGCATCATCGGTGATAATTGTTCCCGGTTACGGTATGGCAGTAGCC
CAGTCTCAGCATATTATAAAAGAGATGGTTGATATATTAGAATGTTCAGATATTAATATACGTTTTGCCGTACATCCGGT
AGCAGGTAGAATGCCGGGGCATATGAATGTTTTACTTGCAGAAGCTAATATAGATTACGATAAAGTACTTGAGCTTGAAG
CAATTAATAGAGATTTCGCTACCACTGACGTAGTGCTTGTGATTGGGGCAAATGATGTAACTAATCCTGCTGCCAAAAAT
GATCCGAACAGTCCAATTTATGGTATGCCGGTACTCGATGCTGAAAAAGCACGTACGATTTTGTTTATTAAACGTTCTAT
GGCTTCAGGATATGCAGGTATAGAAAATGAGCTATTTTATCACGATAATACTTTTATGTTATTCGGCGATGCTAAGAAAG
TAGTTGAGGAGATAGTTAAGTTTCTAAATGAAGATTGA

Upstream 100 bases:

>100_bases
TCGATTTATCTCATGTTATGATTAGTTTCTTCTTTCGCGGGCGTGATATAAGTTTCCACGCAACAACGCAACTCGGGAAT
AACATATAATGATTACCTCT

Downstream 100 bases:

>100_bases
CTTAAATCACTCTATTTGTTATAGTTCCTTGAATTAAGCCAAAAACAATGATCATGAATTCGCAAAAAACATTACCGCTT
CTGCCAAAAGCCACGGCTAT

Product: NAD(p) transhydrogenase subunit beta

Products: NA

Alternate protein names: Nicotinamide nucleotide transhydrogenase subunit beta; Proton-translocating transhydrogenase NADP(H)-binding component; Pyridine nucleotide transhydrogenase subunit beta; dIII [H]

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSLQIIQLLYLVAAVCFILSLKFLSSQKQARLGTTIGTLGMVIAVGVTFFLPDFTHKLPIIATILLGAIIGRIIALKISM
TAIPQLVAGFHSFVGLAAVFVAYSTILAPENFSIGIAGSLTINSLIEISVGVSIGALTFSGSVIAFLKLQGLMKSSPLKF
YGQQYICLLTAIILVILVISFIRSENIFLFNLIVFLSLLIGVLLIIPVGGADMPVILSMLNSYSGFAAAGIGFTLSNSLL
IITGALVGSSGAILSHIMCKAMNRSLIKVIFGAFLPTPTGLHNDIDDDKIVKTSCPEDAAHLLLNASSVIIVPGYGMAVA
QSQHIIKEMVDILECSDINIRFAVHPVAGRMPGHMNVLLAEANIDYDKVLELEAINRDFATTDVVLVIGANDVTNPAAKN
DPNSPIYGMPVLDAEKARTILFIKRSMASGYAGIENELFYHDNTFMLFGDAKKVVEEIVKFLNED

Sequences:

>Translated_465_residues
MSLQIIQLLYLVAAVCFILSLKFLSSQKQARLGTTIGTLGMVIAVGVTFFLPDFTHKLPIIATILLGAIIGRIIALKISM
TAIPQLVAGFHSFVGLAAVFVAYSTILAPENFSIGIAGSLTINSLIEISVGVSIGALTFSGSVIAFLKLQGLMKSSPLKF
YGQQYICLLTAIILVILVISFIRSENIFLFNLIVFLSLLIGVLLIIPVGGADMPVILSMLNSYSGFAAAGIGFTLSNSLL
IITGALVGSSGAILSHIMCKAMNRSLIKVIFGAFLPTPTGLHNDIDDDKIVKTSCPEDAAHLLLNASSVIIVPGYGMAVA
QSQHIIKEMVDILECSDINIRFAVHPVAGRMPGHMNVLLAEANIDYDKVLELEAINRDFATTDVVLVIGANDVTNPAAKN
DPNSPIYGMPVLDAEKARTILFIKRSMASGYAGIENELFYHDNTFMLFGDAKKVVEEIVKFLNED
>Mature_464_residues
SLQIIQLLYLVAAVCFILSLKFLSSQKQARLGTTIGTLGMVIAVGVTFFLPDFTHKLPIIATILLGAIIGRIIALKISMT
AIPQLVAGFHSFVGLAAVFVAYSTILAPENFSIGIAGSLTINSLIEISVGVSIGALTFSGSVIAFLKLQGLMKSSPLKFY
GQQYICLLTAIILVILVISFIRSENIFLFNLIVFLSLLIGVLLIIPVGGADMPVILSMLNSYSGFAAAGIGFTLSNSLLI
ITGALVGSSGAILSHIMCKAMNRSLIKVIFGAFLPTPTGLHNDIDDDKIVKTSCPEDAAHLLLNASSVIIVPGYGMAVAQ
SQHIIKEMVDILECSDINIRFAVHPVAGRMPGHMNVLLAEANIDYDKVLELEAINRDFATTDVVLVIGANDVTNPAAKND
PNSPIYGMPVLDAEKARTILFIKRSMASGYAGIENELFYHDNTFMLFGDAKKVVEEIVKFLNED

Specific function: The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane [H]

COG id: COG1282

COG function: function code C; NAD/NADP transhydrogenase beta subunit

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNT beta subunit family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=482, Percent_Identity=43.5684647302905, Blast_Score=357, Evalue=2e-98,
Organism=Homo sapiens, GI122939153, Length=482, Percent_Identity=43.5684647302905, Blast_Score=357, Evalue=2e-98,
Organism=Escherichia coli, GI1787886, Length=468, Percent_Identity=50.2136752136752, Blast_Score=431, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI17550456, Length=457, Percent_Identity=43.9824945295405, Blast_Score=358, Evalue=2e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012136
- InterPro:   IPR004003 [H]

Pfam domain/function: PF02233 PNTB [H]

EC number: =1.6.1.2 [H]

Molecular weight: Translated: 49811; Mature: 49680

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQIIQLLYLVAAVCFILSLKFLSSQKQARLGTTIGTLGMVIAVGVTFFLPDFTHKLPI
CCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHH
IATILLGAIIGRIIALKISMTAIPQLVAGFHSFVGLAAVFVAYSTILAPENFSIGIAGSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCH
TINSLIEISVGVSIGALTFSGSVIAFLKLQGLMKSSPLKFYGQQYICLLTAIILVILVIS
HHHHHEEEEECCEEEEEEECCCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHH
FIRSENIFLFNLIVFLSLLIGVLLIIPVGGADMPVILSMLNSYSGFAAAGIGFTLSNSLL
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCCEECCCEE
IITGALVGSSGAILSHIMCKAMNRSLIKVIFGAFLPTPTGLHNDIDDDKIVKTSCPEDAA
EEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHH
HLLLNASSVIIVPGYGMAVAQSQHIIKEMVDILECSDINIRFAVHPVAGRMPGHMNVLLA
HHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEE
EANIDYDKVLELEAINRDFATTDVVLVIGANDVTNPAAKNDPNSPIYGMPVLDAEKARTI
ECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCHHHCCEE
LFIKRSMASGYAGIENELFYHDNTFMLFGDAKKVVEEIVKFLNED
EEEEHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SLQIIQLLYLVAAVCFILSLKFLSSQKQARLGTTIGTLGMVIAVGVTFFLPDFTHKLPI
CHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHH
IATILLGAIIGRIIALKISMTAIPQLVAGFHSFVGLAAVFVAYSTILAPENFSIGIAGSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCH
TINSLIEISVGVSIGALTFSGSVIAFLKLQGLMKSSPLKFYGQQYICLLTAIILVILVIS
HHHHHEEEEECCEEEEEEECCCHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHHHHHH
FIRSENIFLFNLIVFLSLLIGVLLIIPVGGADMPVILSMLNSYSGFAAAGIGFTLSNSLL
HHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHHCCCCEECCCEE
IITGALVGSSGAILSHIMCKAMNRSLIKVIFGAFLPTPTGLHNDIDDDKIVKTSCPEDAA
EEEEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCHHHH
HLLLNASSVIIVPGYGMAVAQSQHIIKEMVDILECSDINIRFAVHPVAGRMPGHMNVLLA
HHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCEEEEEE
EANIDYDKVLELEAINRDFATTDVVLVIGANDVTNPAAKNDPNSPIYGMPVLDAEKARTI
ECCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCCCEECCCCCCHHHCCEE
LFIKRSMASGYAGIENELFYHDNTFMLFGDAKKVVEEIVKFLNED
EEEEHHHHCCCCCCCCCEEEECCEEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8075801 [H]