Click here to switch to the map view.

The map label for this gene is 157825164

Identifier: 157825164

GI number: 157825164

Start: 28224

End: 28364

Strand: Direct

Name: 157825164

Synonym: A1C_00205

Alternate gene names: NA

Gene position: 28224-28364 (Clockwise)

Preceding gene: 157825163

Following gene: 157825165

Centisome position: 2.29

GC content: 27.66

Gene sequence:

>141_bases
TTGACTGATAAGAAAATTTTTATTGTTGGAGGGGCAGAAATAGCAATTCTTTGCCTAGAGCAAAATCTTATTGATGAATT
TTTACTTACCAAAATAAATAAAAATTATGATGGAGATACTTTTTTCCCTCTTAATCTTTAG

Upstream 100 bases:

>100_bases
GTATTTGTATTGTTTTTTCAAAGAATGTACCACCACAACTTTATAGTCACAATATATTTTTTATTAAATCTTTAGATGAG
TTTGGCGGGTAATAAAACCT

Downstream 100 bases:

>100_bases
CAGAATGGCATCCTGTAATAATAGATAAAACAAATGATTATCAAATTTACAAATTTATTAAAAAAGAGGTAACATGAAAT
TTTTAGAACAGCTTAATATT

Product: dihydrofolate reductase

Products: 7,8-dihydrofolate; NADPH; H+

Alternate protein names: Dihydrofolate Reductase FolA

Number of amino acids: Translated: 46; Mature: 45

Protein sequence:

>46_residues
MTDKKIFIVGGAEIAILCLEQNLIDEFLLTKINKNYDGDTFFPLNL

Sequences:

>Translated_46_residues
MTDKKIFIVGGAEIAILCLEQNLIDEFLLTKINKNYDGDTFFPLNL
>Mature_45_residues
TDKKIFIVGGAEIAILCLEQNLIDEFLLTKINKNYDGDTFFPLNL

Specific function: Unknown

COG id: COG0262

COG function: function code H; Dihydrofolate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.5.1.3

Molecular weight: Translated: 5233; Mature: 5102

Theoretical pI: Translated: 4.17; Mature: 4.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKKIFIVGGAEIAILCLEQNLIDEFLLTKINKNYDGDTFFPLNL
CCCCEEEEEECCEEEEEEECCHHHHHHHHHHCCCCCCCCEEEEECC
>Mature Secondary Structure 
TDKKIFIVGGAEIAILCLEQNLIDEFLLTKINKNYDGDTFFPLNL
CCCEEEEEECCEEEEEEECCHHHHHHHHHHCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5,6,7,8-tetrahydrofolate; NADP+

Specific reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA