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The map label for this gene is yafV [C]

Identifier: 157372638

GI number: 157372638

Start: 4875372

End: 4876232

Strand: Reverse

Name: yafV [C]

Synonym: Spro_4405

Alternate gene names: 157372638

Gene position: 4876232-4875372 (Counterclockwise)

Preceding gene: 157372639

Following gene: 157372637

Centisome position: 89.49

GC content: 58.42

Gene sequence:

>861_bases
ATGAGAAATGCTAACGTTGCGTTGTTACAGTTGTGCAGTGGCGATCGGGTGCGTGATAACCTGGCCCAGATTGAACAGCA
GATTAAGCAGCTCAATACCGGGGTAAAACTGGTGATGACGCCGGAGAACGCGCTGCTGTTCGCCAATTCTGCGGCTTATC
GTGAACATGCTGAACGCCAGGGCGACGGGCCGCTGCAGAATGCGGTGCGCGAGATGGCACGGCGTTATGGCGTCTGGCTG
CTGGTGGGGTCGATGCCGTTGGTCAGCCGTGAAAATCCTGCGCTGATCACCACCAGCAGCCTGCTGTTCGACGACCAGGG
CGAGATCCGCGCGCGCTATGACAAGCTGCACATGTTCGACGTGGACATTAACGACTCTCACGGCCATTATCGGGAGTCGG
ATACCTATCAGCATGGCCAAGAGCTCCAGGTAGTGGATACCCCGGTCGGGCGGCTTGGCATGACCATCTGCTACGATCTG
CGCTTCCCGGCGCTGTTCCAGGCGTTACGGGCACAGGGCGCCGAACTGATTTCCGTACCGGCGGCCTTTACTCGTGTGAC
CGGTGAGGCGCACTGGGAAATTTTGCTGCGCGCCAGAGCGATAGAAAACCAGTGTGTGATCCTGGCGCCGGCACAGGTTG
GCAGCCATGGCCCGACTCGTCGCACCTGGGGCCATTCGCTGGCGGTGGATGCCTGGGGCAAGGTATTGGCTGAAAACCCC
GATGCGGTATCGGCGTTGAAAGTTCGGGTCGATATAACCGGCCTCAAAACCATTCGCGAGCAAATGCCGGTATTGCAGCA
CAACCGATTCCAGACGTCGCTGACGGCGCCGTTTGACAACAAATTCTCCATTAAAGAGTGA

Upstream 100 bases:

>100_bases
TGTGGAGTAAGATCTCGCTGATTCGTTACCACATCAGCGGCGATTTGGACCAGCCGAAGGTCAACGAGGTCCTGCGTAAG
CCAAAGGAGGATAAGGCGTC

Downstream 100 bases:

>100_bases
AAAAATTATGAGCCTGACGTTTGTCAGTGAGCAGTTACTTGCTGCCAATAAGCTGAGCCACCAGGATCTGTTTTCCGTCC
TGGGGCAACTGGCCGAACGC

Product: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MRNANVALLQLCSGDRVRDNLAQIEQQIKQLNTGVKLVMTPENALLFANSAAYREHAERQGDGPLQNAVREMARRYGVWL
LVGSMPLVSRENPALITTSSLLFDDQGEIRARYDKLHMFDVDINDSHGHYRESDTYQHGQELQVVDTPVGRLGMTICYDL
RFPALFQALRAQGAELISVPAAFTRVTGEAHWEILLRARAIENQCVILAPAQVGSHGPTRRTWGHSLAVDAWGKVLAENP
DAVSALKVRVDITGLKTIREQMPVLQHNRFQTSLTAPFDNKFSIKE

Sequences:

>Translated_286_residues
MRNANVALLQLCSGDRVRDNLAQIEQQIKQLNTGVKLVMTPENALLFANSAAYREHAERQGDGPLQNAVREMARRYGVWL
LVGSMPLVSRENPALITTSSLLFDDQGEIRARYDKLHMFDVDINDSHGHYRESDTYQHGQELQVVDTPVGRLGMTICYDL
RFPALFQALRAQGAELISVPAAFTRVTGEAHWEILLRARAIENQCVILAPAQVGSHGPTRRTWGHSLAVDAWGKVLAENP
DAVSALKVRVDITGLKTIREQMPVLQHNRFQTSLTAPFDNKFSIKE
>Mature_286_residues
MRNANVALLQLCSGDRVRDNLAQIEQQIKQLNTGVKLVMTPENALLFANSAAYREHAERQGDGPLQNAVREMARRYGVWL
LVGSMPLVSRENPALITTSSLLFDDQGEIRARYDKLHMFDVDINDSHGHYRESDTYQHGQELQVVDTPVGRLGMTICYDL
RFPALFQALRAQGAELISVPAAFTRVTGEAHWEILLRARAIENQCVILAPAQVGSHGPTRRTWGHSLAVDAWGKVLAENP
DAVSALKVRVDITGLKTIREQMPVLQHNRFQTSLTAPFDNKFSIKE

Specific function: Unknown

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI297632348, Length=268, Percent_Identity=35.8208955223881, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI297632350, Length=268, Percent_Identity=35.8208955223881, Blast_Score=171, Evalue=5e-43,
Organism=Homo sapiens, GI5031947, Length=268, Percent_Identity=35.8208955223881, Blast_Score=171, Evalue=5e-43,
Organism=Homo sapiens, GI9910460, Length=270, Percent_Identity=31.8518518518519, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI297632346, Length=192, Percent_Identity=32.2916666666667, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1786412, Length=249, Percent_Identity=26.9076305220884, Blast_Score=69, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17556280, Length=268, Percent_Identity=38.0597014925373, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6322335, Length=296, Percent_Identity=33.7837837837838, Blast_Score=154, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6323383, Length=274, Percent_Identity=29.5620437956204, Blast_Score=132, Evalue=7e-32,
Organism=Drosophila melanogaster, GI17933642, Length=271, Percent_Identity=37.6383763837638, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21355835, Length=274, Percent_Identity=27.007299270073, Blast_Score=140, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010
- InterPro:   IPR001110 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 31993; Mature: 31993

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNANVALLQLCSGDRVRDNLAQIEQQIKQLNTGVKLVMTPENALLFANSAAYREHAERQ
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCHHHHHHHHHC
GDGPLQNAVREMARRYGVWLLVGSMPLVSRENPALITTSSLLFDDQGEIRARYDKLHMFD
CCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCHHEEECEEEEEE
VDINDSHGHYRESDTYQHGQELQVVDTPVGRLGMTICYDLRFPALFQALRAQGAELISVP
EEECCCCCCCCCCCCCCCCCEEEEEECCCCHHCCEEEEECCCHHHHHHHHHCCCEEEECC
AAFTRVTGEAHWEILLRARAIENQCVILAPAQVGSHGPTRRTWGHSLAVDAWGKVLAENP
HHHHHHCCCHHHHHEEEHHHCCCCEEEEECHHCCCCCCCCCCCCCEEEHHHHHHHHCCCC
DAVSALKVRVDITGLKTIREQMPVLQHNRFQTSLTAPFDNKFSIKE
CCEEEEEEEEEEHHHHHHHHHCCHHHCCCCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MRNANVALLQLCSGDRVRDNLAQIEQQIKQLNTGVKLVMTPENALLFANSAAYREHAERQ
CCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECCHHHHHHHHHC
GDGPLQNAVREMARRYGVWLLVGSMPLVSRENPALITTSSLLFDDQGEIRARYDKLHMFD
CCCHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEEEEECCCCCHHEEECEEEEEE
VDINDSHGHYRESDTYQHGQELQVVDTPVGRLGMTICYDLRFPALFQALRAQGAELISVP
EEECCCCCCCCCCCCCCCCCEEEEEECCCCHHCCEEEEECCCHHHHHHHHHCCCEEEECC
AAFTRVTGEAHWEILLRARAIENQCVILAPAQVGSHGPTRRTWGHSLAVDAWGKVLAENP
HHHHHHCCCHHHHHEEEHHHCCCCEEEEECHHCCCCCCCCCCCCCEEEHHHHHHHHCCCC
DAVSALKVRVDITGLKTIREQMPVLQHNRFQTSLTAPFDNKFSIKE
CCEEEEEEEEEEHHHHHHHHHCCHHHCCCCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]