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The map label for this gene is tldD [H]

Identifier: 157372637

GI number: 157372637

Start: 4873919

End: 4875364

Strand: Reverse

Name: tldD [H]

Synonym: Spro_4404

Alternate gene names: 157372637

Gene position: 4875364-4873919 (Counterclockwise)

Preceding gene: 157372638

Following gene: 157372636

Centisome position: 89.48

GC content: 58.85

Gene sequence:

>1446_bases
ATGAGCCTGACGTTTGTCAGTGAGCAGTTACTTGCTGCCAATAAGCTGAGCCACCAGGATCTGTTTTCCGTCCTGGGGCA
ACTGGCCGAACGCCGCCTCGATTACGCCGATCTCTATTTCCAGTCGAGCTACCACGAAGCCTGGGTGATTGAAGACGGTA
TCATCAAGGATGGCTCTTACAATATCGACCAAGGGGTTGGAGTACGCGCCGTGAGCGGCGAGAAAACCGGCTTCGCCTAT
GCCGATCAAATCACCCTGAACGCCTTGCAGCAAAGCGCCCATGCCGCGCGCAGCATAGTGCGTGACAGCGGTAATGGTCA
GGTGCATACCTTGGGTGAAATCAGCCATAAGGCGCTGTATCCCCTGCTCGATCCGCTGCAAAGCCTGCCGCGGGAAGAGA
AAATCGCCCTGTTGCACCGCATTGACAAGGTAGCCCGCGCGGCCGATAAGCGGGTGCAGGAAGTTAGCGCCAGTATCACC
GGCGTGTATGAACAAATTCTGGTGGCGGCCACCGACGGTACTCTGGCTGCGGACGTTCGCCCATTAGTGCGCTTGTCTGT
CAGCGTACTGGTGGAGCAAGACGGCAAGCGTGAACGCGGTTCCAGCGGCGGCGGTGGCCGTTTCGGCTATGACTATTTCC
TGGAAATCGCCGATGGCGAAGTCCGTGCTGACGCCTACGCCAAAGAAGCGGTGCGCATGGCATTGATTAACCTTTCTGCC
GTTGCAGCCCCAGCCGGTAATATGCCGGTGGTGCTGGGCGCAGGCTGGCCGGGCGTCCTGCTGCATGAAGCGGTGGGCCA
TGGTCTGGAAGGCGACTTCAACCGTCGTGGTACTTCGGTCTTCAGCGGCCAGATGGGTCAGTTGGTGGCTTCCGAGCTTT
GTACGGTGGTGGATGACGGCACTTTGCAGGGGTTACGAGGTTCACTGGCGATCGATGACGAAGGCGTACCGGGCCAGTAC
AACATGTTGATTGAGAACGGTATCCTGAAAGGTTATATGCAGGACAAACTCAATGCGCGTCTGATGGGCGTTGCGCCGAC
CGGTAACGGCCGCCGTGAGTCCTATGCGCATCTGCCGATGCCGCGCATGACCAACACCTACATGCTGGCGGGCAAGTCTA
CGCCGGAAGAGATCATCGCCAGCGTTGAATACGGCCTGTACGCGCCGAACTTTGGCGGCGGCCAGGTGGATATCACCTCC
GGCAAGTTTGTGTTTTCCACCACCGAAGCCTACCTGATCGAAAAAGGTCGCATCACCAAGCCGGTGAAGGGCGCCACCCT
GATCGGCTCCGGTATTGAGGCGATGCAGCAGATTTCGATGGTGGGCAACGATCTGGCGCTGGATAAAGGCGTCGGCGTTT
GCGGTAAAGAGGGGCAAAGCCTGCCGGTGGGGGTTGGTCAACCGACCCTGAAGCTGGACACCCTGACCGTCGGTGGTACC
GCGTAA

Upstream 100 bases:

>100_bases
ACCATTCGCGAGCAAATGCCGGTATTGCAGCACAACCGATTCCAGACGTCGCTGACGGCGCCGTTTGACAACAAATTCTC
CATTAAAGAGTGAAAAAATT

Downstream 100 bases:

>100_bases
TACTTTCCAGGGGCCGGTTCACGGCCCCTATCCGTTTCTGTTTTGCGGCGCTCATCGCATTAGCAGCAATTTTTGGGTTT
AGCTGAAATAAAGAGCGATC

Product: protease TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSLTFVSEQLLAANKLSHQDLFSVLGQLAERRLDYADLYFQSSYHEAWVIEDGIIKDGSYNIDQGVGVRAVSGEKTGFAY
ADQITLNALQQSAHAARSIVRDSGNGQVHTLGEISHKALYPLLDPLQSLPREEKIALLHRIDKVARAADKRVQEVSASIT
GVYEQILVAATDGTLAADVRPLVRLSVSVLVEQDGKRERGSSGGGGRFGYDYFLEIADGEVRADAYAKEAVRMALINLSA
VAAPAGNMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQMGQLVASELCTVVDDGTLQGLRGSLAIDDEGVPGQY
NMLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGKSTPEEIIASVEYGLYAPNFGGGQVDITS
GKFVFSTTEAYLIEKGRITKPVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDTLTVGGT
A

Sequences:

>Translated_481_residues
MSLTFVSEQLLAANKLSHQDLFSVLGQLAERRLDYADLYFQSSYHEAWVIEDGIIKDGSYNIDQGVGVRAVSGEKTGFAY
ADQITLNALQQSAHAARSIVRDSGNGQVHTLGEISHKALYPLLDPLQSLPREEKIALLHRIDKVARAADKRVQEVSASIT
GVYEQILVAATDGTLAADVRPLVRLSVSVLVEQDGKRERGSSGGGGRFGYDYFLEIADGEVRADAYAKEAVRMALINLSA
VAAPAGNMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQMGQLVASELCTVVDDGTLQGLRGSLAIDDEGVPGQY
NMLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGKSTPEEIIASVEYGLYAPNFGGGQVDITS
GKFVFSTTEAYLIEKGRITKPVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDTLTVGGT
A
>Mature_480_residues
SLTFVSEQLLAANKLSHQDLFSVLGQLAERRLDYADLYFQSSYHEAWVIEDGIIKDGSYNIDQGVGVRAVSGEKTGFAYA
DQITLNALQQSAHAARSIVRDSGNGQVHTLGEISHKALYPLLDPLQSLPREEKIALLHRIDKVARAADKRVQEVSASITG
VYEQILVAATDGTLAADVRPLVRLSVSVLVEQDGKRERGSSGGGGRFGYDYFLEIADGEVRADAYAKEAVRMALINLSAV
AAPAGNMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQMGQLVASELCTVVDDGTLQGLRGSLAIDDEGVPGQYN
MLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPMPRMTNTYMLAGKSTPEEIIASVEYGLYAPNFGGGQVDITSG
KFVFSTTEAYLIEKGRITKPVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDTLTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=481, Percent_Identity=84.8232848232848, Blast_Score=814, Evalue=0.0,
Organism=Escherichia coli, GI1790682, Length=409, Percent_Identity=23.7163814180929, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51174; Mature: 51043

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTFVSEQLLAANKLSHQDLFSVLGQLAERRLDYADLYFQSSYHEAWVIEDGIIKDGSY
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHEECCCCCEEEEECCEECCCCC
NIDQGVGVRAVSGEKTGFAYADQITLNALQQSAHAARSIVRDSGNGQVHTLGEISHKALY
CCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
PLLDPLQSLPREEKIALLHRIDKVARAADKRVQEVSASITGVYEQILVAATDGTLAADVR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHH
PLVRLSVSVLVEQDGKRERGSSGGGGRFGYDYFLEIADGEVRADAYAKEAVRMALINLSA
HHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VAAPAGNMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQMGQLVASELCTVVDDG
HCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC
TLQGLRGSLAIDDEGVPGQYNMLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
CHHCCCCCEEECCCCCCCCEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
PRMTNTYMLAGKSTPEEIIASVEYGLYAPNFGGGQVDITSGKFVFSTTEAYLIEKGRITK
CCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEECCCEEEEECCCCCC
PVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDTLTVGGT
CCCCCEEEHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
A
C
>Mature Secondary Structure 
SLTFVSEQLLAANKLSHQDLFSVLGQLAERRLDYADLYFQSSYHEAWVIEDGIIKDGSY
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHHHEECCCCCEEEEECCEECCCCC
NIDQGVGVRAVSGEKTGFAYADQITLNALQQSAHAARSIVRDSGNGQVHTLGEISHKALY
CCCCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHH
PLLDPLQSLPREEKIALLHRIDKVARAADKRVQEVSASITGVYEQILVAATDGTLAADVR
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHH
PLVRLSVSVLVEQDGKRERGSSGGGGRFGYDYFLEIADGEVRADAYAKEAVRMALINLSA
HHHHHHHHHEEECCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VAAPAGNMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQMGQLVASELCTVVDDG
HCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHCCC
TLQGLRGSLAIDDEGVPGQYNMLIENGILKGYMQDKLNARLMGVAPTGNGRRESYAHLPM
CHHCCCCCEEECCCCCCCCEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCC
PRMTNTYMLAGKSTPEEIIASVEYGLYAPNFGGGQVDITSGKFVFSTTEAYLIEKGRITK
CCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCEEEEECCEEEEECCCEEEEECCCCCC
PVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSLPVGVGQPTLKLDTLTVGGT
CCCCCEEEHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]