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The map label for this gene is mocR [H]

Identifier: 157372540

GI number: 157372540

Start: 4775913

End: 4777379

Strand: Direct

Name: mocR [H]

Synonym: Spro_4307

Alternate gene names: 157372540

Gene position: 4775913-4777379 (Clockwise)

Preceding gene: 157372536

Following gene: 157372542

Centisome position: 87.65

GC content: 60.05

Gene sequence:

>1467_bases
TTGCGCTCACTGAGTGGTGACCTGTTATTGCAGCGTCTCGGCGAACAGCCCGATGATAAGCTGCATAAACGGCTCTATAA
TGCGATCCGTACCAGCATTCTGGACGGTAGCCTGCCGCCCTCCAGCCGCCTGCCCGCCTCACGCGATTTAGCGCAGGAGC
TTAGCCTTTCACGTAACACGGTTTTAACCGTTTATGAACAATTGCTGGCAGAAGGATATGTTCTGGCACGCGCGGGAAGT
GGCACATTCGTCGCCGAAACCGTGCCAGATAGTTGTTTATCCACTGCCAGCGCCCCGGCAGGCAGTGACGGGGTGCAACG
AGGTATTGAACTGTCAGAGCGCGGCGCCGCTCTGTTGCATCACGCCAGCGCCAGTCCCAAACAATGGGGCGCGTTTATCC
CCGGCGTGCCCGATGTTAATGCCTTCCCTCATCAGTTATTCAGCAAGATCCAGGCACGCATTAGCCGTCGCCCAGCCCCG
CAGAAACTGACCTACAGCAACCAGGGCGGCAGCCCGGAACTGCAACATGCGCTGGTGGATTATCTGCGCGTAGCGCGTTC
GGTACGCTGTTCGCCGGAGCAGATTCTGATTACCGAGGGCATCCATCAGGCGATAGATCTGGTGACGCGGCTGCTGTGTA
ATCCGGGCGACGATGCCTGGATTGAAGAGCCGGGCTATTGGGGGATCCGCAATATCCTGCGAATGAACGACGTGAATATC
TGCCCACTGGAAGTTGATGAGGCCGGCATGGTGCCGCCGGAGCAGCCCAGCGGCCCACCACGGTTGATATTTGTCACCCC
GTCGCACCAATATCCGTTGGGATCGGTGATGAGCCTGGCGCGGCGACAACGCTTGCTGGCACTGGCACGCAACGGCGGCA
GCTGGATCGTTGAGGATGACTACGACAGTGAATTCCGCTTTTCTGGCCAGCCGATCCCGGCATTGCAGGGGCTGGAAGCC
GACGCACCGGTGATCTATATCGGCACCTTCAGTAAAACGCTGTACCCGGCGCTACGGCTGGGCTACGTGGTGTTGCCAAA
GCCGCTGGTCGCGGCGTTGAAAACCGCCCATGCCGAGCTGTACCGCGGCGGTCATCTGCTGATCCAGACCGCATTGGCGC
AGTTTATTCAGGAAGGCCATTACACCGCGCATATTCGCCGCATGCGGCTGCTGTATGCCCGCCGCCGGGCGTTTCTGACC
GCATTGATCGAGCAGCATCTGGGCAAGCAGGCGTTGAGCGAGTTCAACAACAACGCCGGCCTGCACCTGATCCTAAACCT
GCCTGACGAGGCGGACGACGTGGCTATCGCCGCCGCTGCCAACGAACGCGGCGTGCTGGTGCGGCCGCTGTCGCGTTACT
ACATGCTGCCCAACCATCGCCGTGGCCTGCTGATGGGGTTTGCCTGCGTGCCAGAAGAACAAATGGCCGCCGCCTTTACC
TTGCTGCTGGAATGCATCCGTCCCTGA

Upstream 100 bases:

>100_bases
CAGTTGTACGTTTCGTTCACATTCGTGAAACAATGGCGTTTATTTACACAGGATGTGGCCCTATAATCGAGAGCCAGTTA
CGATTAATTGAGGGATCCAA

Downstream 100 bases:

>100_bases
GCGCTGTTTTCCATCAAAGGCTCTGCAATTGCCACCCTTCCTGCCGCCATTGCAAACGGTGAGTTAATTTCAGCGCCTGC
AAAAACGCTTCATCATGGGA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 488; Mature: 488

Protein sequence:

>488_residues
MRSLSGDLLLQRLGEQPDDKLHKRLYNAIRTSILDGSLPPSSRLPASRDLAQELSLSRNTVLTVYEQLLAEGYVLARAGS
GTFVAETVPDSCLSTASAPAGSDGVQRGIELSERGAALLHHASASPKQWGAFIPGVPDVNAFPHQLFSKIQARISRRPAP
QKLTYSNQGGSPELQHALVDYLRVARSVRCSPEQILITEGIHQAIDLVTRLLCNPGDDAWIEEPGYWGIRNILRMNDVNI
CPLEVDEAGMVPPEQPSGPPRLIFVTPSHQYPLGSVMSLARRQRLLALARNGGSWIVEDDYDSEFRFSGQPIPALQGLEA
DAPVIYIGTFSKTLYPALRLGYVVLPKPLVAALKTAHAELYRGGHLLIQTALAQFIQEGHYTAHIRRMRLLYARRRAFLT
ALIEQHLGKQALSEFNNNAGLHLILNLPDEADDVAIAAAANERGVLVRPLSRYYMLPNHRRGLLMGFACVPEEQMAAAFT
LLLECIRP

Sequences:

>Translated_488_residues
MRSLSGDLLLQRLGEQPDDKLHKRLYNAIRTSILDGSLPPSSRLPASRDLAQELSLSRNTVLTVYEQLLAEGYVLARAGS
GTFVAETVPDSCLSTASAPAGSDGVQRGIELSERGAALLHHASASPKQWGAFIPGVPDVNAFPHQLFSKIQARISRRPAP
QKLTYSNQGGSPELQHALVDYLRVARSVRCSPEQILITEGIHQAIDLVTRLLCNPGDDAWIEEPGYWGIRNILRMNDVNI
CPLEVDEAGMVPPEQPSGPPRLIFVTPSHQYPLGSVMSLARRQRLLALARNGGSWIVEDDYDSEFRFSGQPIPALQGLEA
DAPVIYIGTFSKTLYPALRLGYVVLPKPLVAALKTAHAELYRGGHLLIQTALAQFIQEGHYTAHIRRMRLLYARRRAFLT
ALIEQHLGKQALSEFNNNAGLHLILNLPDEADDVAIAAAANERGVLVRPLSRYYMLPNHRRGLLMGFACVPEEQMAAAFT
LLLECIRP
>Mature_488_residues
MRSLSGDLLLQRLGEQPDDKLHKRLYNAIRTSILDGSLPPSSRLPASRDLAQELSLSRNTVLTVYEQLLAEGYVLARAGS
GTFVAETVPDSCLSTASAPAGSDGVQRGIELSERGAALLHHASASPKQWGAFIPGVPDVNAFPHQLFSKIQARISRRPAP
QKLTYSNQGGSPELQHALVDYLRVARSVRCSPEQILITEGIHQAIDLVTRLLCNPGDDAWIEEPGYWGIRNILRMNDVNI
CPLEVDEAGMVPPEQPSGPPRLIFVTPSHQYPLGSVMSLARRQRLLALARNGGSWIVEDDYDSEFRFSGQPIPALQGLEA
DAPVIYIGTFSKTLYPALRLGYVVLPKPLVAALKTAHAELYRGGHLLIQTALAQFIQEGHYTAHIRRMRLLYARRRAFLT
ALIEQHLGKQALSEFNNNAGLHLILNLPDEADDVAIAAAANERGVLVRPLSRYYMLPNHRRGLLMGFACVPEEQMAAAFT
LLLECIRP

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=407, Percent_Identity=25.3071253071253, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI33469970, Length=407, Percent_Identity=25.3071253071253, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1790797, Length=403, Percent_Identity=28.0397022332506, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1787710, Length=444, Percent_Identity=24.7747747747748, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321236, Length=348, Percent_Identity=21.264367816092, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53709; Mature: 53709

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSLSGDLLLQRLGEQPDDKLHKRLYNAIRTSILDGSLPPSSRLPASRDLAQELSLSRNT
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCH
VLTVYEQLLAEGYVLARAGSGTFVAETVPDSCLSTASAPAGSDGVQRGIELSERGAALLH
HHHHHHHHHHCCEEEEECCCCCEEECCCCHHHHHHCCCCCCCHHHHHCCCHHHCCHHHHH
HASASPKQWGAFIPGVPDVNAFPHQLFSKIQARISRRPAPQKLTYSNQGGSPELQHALVD
HCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHH
YLRVARSVRCSPEQILITEGIHQAIDLVTRLLCNPGDDAWIEEPGYWGIRNILRMNDVNI
HHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCC
CPLEVDEAGMVPPEQPSGPPRLIFVTPSHQYPLGSVMSLARRQRLLALARNGGSWIVEDD
CEEECCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECC
YDSEFRFSGQPIPALQGLEADAPVIYIGTFSKTLYPALRLGYVVLPKPLVAALKTAHAEL
CCCCEEECCCCCCHHCCCCCCCCEEEEECCHHHHHHHHHHCEEECCHHHHHHHHHHHHHH
YRGGHLLIQTALAQFIQEGHYTAHIRRMRLLYARRRAFLTALIEQHLGKQALSEFNNNAG
HCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
LHLILNLPDEADDVAIAAAANERGVLVRPLSRYYMLPNHRRGLLMGFACVPEEQMAAAFT
EEEEEECCCCCCCEEEEEECCCCCEEEEEHHHHHCCCCCCCCEEEEEECCCHHHHHHHHH
LLLECIRP
HHHHHHCC
>Mature Secondary Structure
MRSLSGDLLLQRLGEQPDDKLHKRLYNAIRTSILDGSLPPSSRLPASRDLAQELSLSRNT
CCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCH
VLTVYEQLLAEGYVLARAGSGTFVAETVPDSCLSTASAPAGSDGVQRGIELSERGAALLH
HHHHHHHHHHCCEEEEECCCCCEEECCCCHHHHHHCCCCCCCHHHHHCCCHHHCCHHHHH
HASASPKQWGAFIPGVPDVNAFPHQLFSKIQARISRRPAPQKLTYSNQGGSPELQHALVD
HCCCCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHH
YLRVARSVRCSPEQILITEGIHQAIDLVTRLLCNPGDDAWIEEPGYWGIRNILRMNDVNI
HHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCC
CPLEVDEAGMVPPEQPSGPPRLIFVTPSHQYPLGSVMSLARRQRLLALARNGGSWIVEDD
CEEECCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECC
YDSEFRFSGQPIPALQGLEADAPVIYIGTFSKTLYPALRLGYVVLPKPLVAALKTAHAEL
CCCCEEECCCCCCHHCCCCCCCCEEEEECCHHHHHHHHHHCEEECCHHHHHHHHHHHHHH
YRGGHLLIQTALAQFIQEGHYTAHIRRMRLLYARRRAFLTALIEQHLGKQALSEFNNNAG
HCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCC
LHLILNLPDEADDVAIAAAANERGVLVRPLSRYYMLPNHRRGLLMGFACVPEEQMAAAFT
EEEEEECCCCCCCEEEEEECCCCCEEEEEHHHHHCCCCCCCCEEEEEECCCHHHHHHHHH
LLLECIRP
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]