Click here to switch to the map view.

The map label for this gene is fadH [H]

Identifier: 157372542

GI number: 157372542

Start: 4779311

End: 4781332

Strand: Direct

Name: fadH [H]

Synonym: Spro_4309

Alternate gene names: 157372542

Gene position: 4779311-4781332 (Clockwise)

Preceding gene: 157372540

Following gene: 157372543

Centisome position: 87.71

GC content: 61.77

Gene sequence:

>2022_bases
ATGAGCAATTACCCACACCTGCTGGCGCCGCTGGATCTCGGCTTCACTACCCTGAAAAATCGGGTGCTGATGGGATCGAT
GCACACCGGCCTGGAAGAACTGCCCAATGGCCCCGAGCGCATGGCCGCTTTCTATGCCGAACGCGCGGCGGCCGGTGTAG
CGCTAATCGTCACCGGCGGGATCGCCCCCAATGAAAAGGGCGTGGTGTATCGCGGCGGCTCCACCCTCAGCCACCCACAG
CAGGTCAGCCACCACCGCATCGTCACCGAGGCCGTTCATCAGGCCGGCGGTAAAATTGCGCTGCAGATCCTGCATGCCGG
TCGCTACAGTTATCAGCCGCAGCCGGTCGCCCCCTCCGCGCTGCAGGCACCGATCAATCCCTTCGCTCCCACTGCGCTGA
GCGAGGCGGAGATCGTGCAGACCATCGCCGACTTCGCCCAGTGTGCGGCACTGGCGCAGCAGGCCGGTTACGATGGCGTC
GAGGTGATGGGTTCCGAAGGTTATCTGATCAACCAATTTCTGGTGTCGCGCACCAACCAGCGCGACGACCAATGGGGCGG
CAGCTTCAGCAACCGCATGCGTTTTGCCGTGGAGATCGTCCGGGCGGTGCGGCAGGCGGTCGGCAGCGATTTCATTCTGA
TTTACCGCCTTTCGATGCTGGATCTGGTGGAAGAGGGTTCCAGCTGGCAGGAGATCGAACAGTTGGCACTGGCAGTTGAG
CAGGCGGGGGCGACCATCATCAACACTGGTATCGGTTGGCATGAGGCGCGTATCCCGACCATCGCTACCATGGTGCCACG
TGCCGGTTTCAGCTGGGTAACTCGTAAGCTGATGGGCAAAGTGCGCATTCCGCTGATCACCACCAACCGCATTAACGATC
CGGCCGTTGCCGAGCAGGTGCTGGCAGACGGCTGCGCCGACATGGTGTCGATGGCCCGTCCGTTCCTGGCCGATGCCGCC
TTTGTGCAAAAGGCAGCCGAAGGCCGCGCCGACGAAATCAATACCTGTATTGGCTGTAACCAGGCCTGCCTCGACCAGAT
TTTTGAAGGCAAACTCACCTCTTGCCTGGTTAACCCACGCGCCTGCCGCGAAACCGAAATGCCACTGGTTCCGGCAGAAA
AACCGAAGAAACTGGCGGTGATCGGCGCCGGGCCAGCCGGGCTGGCCTTTGCCACCACCGCCGCCAGCCGCGGCCACCGG
GTGACGCTGTTCGACGCTGCCGACCAGATTGGCGGCCAGTTCAATATTGCCAAACAGATCCCCGGCAAAGAGGAATTTCA
TGAAACCCTGCGCTACTTCCGCCGCCAATTGGCGCTGCTGGAGGTGACGCTGAAACTGGGTACCTGGGTGACGGCGGCCG
ATCTGGCAGAATTTGACGAAGTGATCCTCGCCTGCGGCATCGTGCCACGTACCCCGGAGATCCCTGGCATCGATAACGCC
AGAGTCTTGACCTATCTGGACGTGCTGCGCGACAAAAAACCGGTCGGCCAGCGGGTAGCGATTATCGGGGCCGGCGGTAT
CGGCTTCGACACCGCCGAGTACCTCAGCCAGCACGGCGTGTCGAGCAGCCTGGATCAGGCGGAGTTTAACCGTGAATGGG
GCATCGACAACCAGCTTAACCATCGCGGCGGTCTGGCAGCCGAAGGGCCTGTGGCGACGCACGCGGCTCGGCAGATTTAT
CTGCTGCAACGCAAGACCAGCAAAGTGGGTGAAGGCCTGGGGAAAACCACCGGTTGGATCCACCGCACCAGTCTGGCGAT
GCGCGGCGTAAAAATGCTCAACAGCGTGAATTATCAACGCATTGATGACGAAGGCCTGCATATTTCACGAGCCGAACAGG
AAAGTTGCCTGCCGGTAGACACGGTGATTATCTGCGCCGGGCAGGAACCGCGCCGCGAGCTGCAACAGCCGCTGCTGGAG
ATGGGCAAAACGGTGCATTTGATCGGCGGAGCGGACGTGGCCGCCGAGCTGGATGCCCGCCGCGCTATCGATCAGGGCAC
GCGGCTGGCGATGGCTCTGTAA

Upstream 100 bases:

>100_bases
CAATGCAGATTCCCAACCGCAGTGAAGACGGCTAGATTTATCTCATCCGACCACTTGGTCGTACATAATAATAACGATGA
AAGACGCGATGGAGACTGCA

Downstream 100 bases:

>100_bases
AAAATTGCCACTATAGTGGCAAAAAACACCTATATATGACCTTAATTGCTATAATAGTAGCAATTAAGGTTGTCATAGGT
GCACCATGATTTCCCTACAT

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 673; Mature: 672

Protein sequence:

>673_residues
MSNYPHLLAPLDLGFTTLKNRVLMGSMHTGLEELPNGPERMAAFYAERAAAGVALIVTGGIAPNEKGVVYRGGSTLSHPQ
QVSHHRIVTEAVHQAGGKIALQILHAGRYSYQPQPVAPSALQAPINPFAPTALSEAEIVQTIADFAQCAALAQQAGYDGV
EVMGSEGYLINQFLVSRTNQRDDQWGGSFSNRMRFAVEIVRAVRQAVGSDFILIYRLSMLDLVEEGSSWQEIEQLALAVE
QAGATIINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVRIPLITTNRINDPAVAEQVLADGCADMVSMARPFLADAA
FVQKAAEGRADEINTCIGCNQACLDQIFEGKLTSCLVNPRACRETEMPLVPAEKPKKLAVIGAGPAGLAFATTAASRGHR
VTLFDAADQIGGQFNIAKQIPGKEEFHETLRYFRRQLALLEVTLKLGTWVTAADLAEFDEVILACGIVPRTPEIPGIDNA
RVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQHGVSSSLDQAEFNREWGIDNQLNHRGGLAAEGPVATHAARQIY
LLQRKTSKVGEGLGKTTGWIHRTSLAMRGVKMLNSVNYQRIDDEGLHISRAEQESCLPVDTVIICAGQEPRRELQQPLLE
MGKTVHLIGGADVAAELDARRAIDQGTRLAMAL

Sequences:

>Translated_673_residues
MSNYPHLLAPLDLGFTTLKNRVLMGSMHTGLEELPNGPERMAAFYAERAAAGVALIVTGGIAPNEKGVVYRGGSTLSHPQ
QVSHHRIVTEAVHQAGGKIALQILHAGRYSYQPQPVAPSALQAPINPFAPTALSEAEIVQTIADFAQCAALAQQAGYDGV
EVMGSEGYLINQFLVSRTNQRDDQWGGSFSNRMRFAVEIVRAVRQAVGSDFILIYRLSMLDLVEEGSSWQEIEQLALAVE
QAGATIINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVRIPLITTNRINDPAVAEQVLADGCADMVSMARPFLADAA
FVQKAAEGRADEINTCIGCNQACLDQIFEGKLTSCLVNPRACRETEMPLVPAEKPKKLAVIGAGPAGLAFATTAASRGHR
VTLFDAADQIGGQFNIAKQIPGKEEFHETLRYFRRQLALLEVTLKLGTWVTAADLAEFDEVILACGIVPRTPEIPGIDNA
RVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQHGVSSSLDQAEFNREWGIDNQLNHRGGLAAEGPVATHAARQIY
LLQRKTSKVGEGLGKTTGWIHRTSLAMRGVKMLNSVNYQRIDDEGLHISRAEQESCLPVDTVIICAGQEPRRELQQPLLE
MGKTVHLIGGADVAAELDARRAIDQGTRLAMAL
>Mature_672_residues
SNYPHLLAPLDLGFTTLKNRVLMGSMHTGLEELPNGPERMAAFYAERAAAGVALIVTGGIAPNEKGVVYRGGSTLSHPQQ
VSHHRIVTEAVHQAGGKIALQILHAGRYSYQPQPVAPSALQAPINPFAPTALSEAEIVQTIADFAQCAALAQQAGYDGVE
VMGSEGYLINQFLVSRTNQRDDQWGGSFSNRMRFAVEIVRAVRQAVGSDFILIYRLSMLDLVEEGSSWQEIEQLALAVEQ
AGATIINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVRIPLITTNRINDPAVAEQVLADGCADMVSMARPFLADAAF
VQKAAEGRADEINTCIGCNQACLDQIFEGKLTSCLVNPRACRETEMPLVPAEKPKKLAVIGAGPAGLAFATTAASRGHRV
TLFDAADQIGGQFNIAKQIPGKEEFHETLRYFRRQLALLEVTLKLGTWVTAADLAEFDEVILACGIVPRTPEIPGIDNAR
VLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQHGVSSSLDQAEFNREWGIDNQLNHRGGLAAEGPVATHAARQIYL
LQRKTSKVGEGLGKTTGWIHRTSLAMRGVKMLNSVNYQRIDDEGLHISRAEQESCLPVDTVIICAGQEPRRELQQPLLEM
GKTVHLIGGADVAAELDARRAIDQGTRLAMAL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=671, Percent_Identity=70.7898658718331, Blast_Score=971, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=348, Percent_Identity=31.6091954022989, Blast_Score=122, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17540738, Length=254, Percent_Identity=24.4094488188976, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17559804, Length=285, Percent_Identity=25.2631578947368, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17559802, Length=254, Percent_Identity=26.3779527559055, Blast_Score=84, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17564188, Length=257, Percent_Identity=25.2918287937743, Blast_Score=82, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17565138, Length=199, Percent_Identity=26.6331658291457, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17566914, Length=238, Percent_Identity=26.0504201680672, Blast_Score=76, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI72001454, Length=180, Percent_Identity=28.8888888888889, Blast_Score=76, Evalue=5e-14,
Organism=Saccharomyces cerevisiae, GI6321973, Length=234, Percent_Identity=29.4871794871795, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6325086, Length=238, Percent_Identity=29.8319327731092, Blast_Score=86, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 72797; Mature: 72666

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYPHLLAPLDLGFTTLKNRVLMGSMHTGLEELPNGPERMAAFYAERAAAGVALIVTGG
CCCCCCEEEEHHCCHHHHHHHHEECHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECC
IAPNEKGVVYRGGSTLSHPQQVSHHRIVTEAVHQAGGKIALQILHAGRYSYQPQPVAPSA
CCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHH
LQAPINPFAPTALSEAEIVQTIADFAQCAALAQQAGYDGVEVMGSEGYLINQFLVSRTNQ
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCC
RDDQWGGSFSNRMRFAVEIVRAVRQAVGSDFILIYRLSMLDLVEEGSSWQEIEQLALAVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
QAGATIINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVRIPLITTNRINDPAVAEQV
HCCCEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCEECEEEECCCCCCHHHHHHH
LADGCADMVSMARPFLADAAFVQKAAEGRADEINTCIGCNQACLDQIFEGKLTSCLVNPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHCCCH
ACRETEMPLVPAEKPKKLAVIGAGPAGLAFATTAASRGHRVTLFDAADQIGGQFNIAKQI
HHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCEEEEEECHHHCCCCEEEHHCC
PGKEEFHETLRYFRRQLALLEVTLKLGTWVTAADLAEFDEVILACGIVPRTPEIPGIDNA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQHGVSSSLDQAEFNREWGIDNQLN
HHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCC
HRGGLAAEGPVATHAARQIYLLQRKTSKVGEGLGKTTGWIHRTSLAMRGVKMLNSVNYQR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCE
IDDEGLHISRAEQESCLPVDTVIICAGQEPRRELQQPLLEMGKTVHLIGGADVAAELDAR
ECCCCCEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
RAIDQGTRLAMAL
HHHHCCCEEEECC
>Mature Secondary Structure 
SNYPHLLAPLDLGFTTLKNRVLMGSMHTGLEELPNGPERMAAFYAERAAAGVALIVTGG
CCCCCEEEEHHCCHHHHHHHHEECHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEEECC
IAPNEKGVVYRGGSTLSHPQQVSHHRIVTEAVHQAGGKIALQILHAGRYSYQPQPVAPSA
CCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCHH
LQAPINPFAPTALSEAEIVQTIADFAQCAALAQQAGYDGVEVMGSEGYLINQFLVSRTNQ
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEHHHHHHHCCCC
RDDQWGGSFSNRMRFAVEIVRAVRQAVGSDFILIYRLSMLDLVEEGSSWQEIEQLALAVE
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHH
QAGATIINTGIGWHEARIPTIATMVPRAGFSWVTRKLMGKVRIPLITTNRINDPAVAEQV
HCCCEEEECCCCCCCCCCCHHHHHHCCCCHHHHHHHHHCCEECEEEECCCCCCHHHHHHH
LADGCADMVSMARPFLADAAFVQKAAEGRADEINTCIGCNQACLDQIFEGKLTSCLVNPR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHCCHHHHHHCCCH
ACRETEMPLVPAEKPKKLAVIGAGPAGLAFATTAASRGHRVTLFDAADQIGGQFNIAKQI
HHCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHCCCCCEEEEEECHHHCCCCEEEHHCC
PGKEEFHETLRYFRRQLALLEVTLKLGTWVTAADLAEFDEVILACGIVPRTPEIPGIDNA
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
RVLTYLDVLRDKKPVGQRVAIIGAGGIGFDTAEYLSQHGVSSSLDQAEFNREWGIDNQLN
HHHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCC
HRGGLAAEGPVATHAARQIYLLQRKTSKVGEGLGKTTGWIHRTSLAMRGVKMLNSVNYQR
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCCCE
IDDEGLHISRAEQESCLPVDTVIICAGQEPRRELQQPLLEMGKTVHLIGGADVAAELDAR
ECCCCCEEECCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEEECCCCHHHHHHHH
RAIDQGTRLAMAL
HHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]