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The map label for this gene is speC [H]

Identifier: 157372281

GI number: 157372281

Start: 4483726

End: 4485888

Strand: Reverse

Name: speC [H]

Synonym: Spro_4047

Alternate gene names: 157372281

Gene position: 4485888-4483726 (Counterclockwise)

Preceding gene: 157372282

Following gene: 157372280

Centisome position: 82.33

GC content: 56.77

Gene sequence:

>2163_bases
ATGAAAGAATTGAAAATAGCCACCAGCGCCAGTTTGGTTGCCACCATTGAAACACTGCGCCAGGTCGTCCGCATCGAGCA
AACGGACTACACCGACGTGGCCGCGTTAGTGGTGTCGGTTGATGACGTCAACGCAGGTCATCTGGCGCAGCTCAAAGCGA
CCGGGTTCGAAATACCGACCTTTGTGGCGGTGGCAGGGGACGAGCACCTCTCTCCGGACTACCTGCCGTTGATCAGCGGT
GTTTTTGCGCTGGAAGGCGCCAGCAAGGCGTTCTATATGGCACAGCTCGAAGCCGCCGCCGATGCCTACGAGCAGGCTCT
GCTGCCGCCGTTTTTCAAGACGCTGAAAACCTATGTGGAAATGGAAAACTCAACCTTTGCCTGCCCGGGCCATCAGGGCG
GCGAGTTTTTCCGCAAGCACCCGGCCGGCCGGAAGTTTTTTGAGTTCTACGGTGAAACGCTTTTTCGTTCTGACATGTGC
AACGCCGACGTTAAGCTGGGCGATTTATTGATCCACGAAGGCTCGGCCAAGGATGCGCAAAAGCATGCGGCCCGGGTATT
CAACGCCGATAAAACCTATTTCGTGCTTAATGGTACCTCTGCCGCCAATAAGGTCGTGACCAATGCTTTGCTGACCCGGG
GTGATTTGGTGTTGTTCGATCGCAACAACCACAAGTCCAACCACCACGGTGCACTGATCCAGGCCGGGGCAACGCCGGTC
TATCTGGAAACCGCGCGTAACCCGTTTGGTTTCATCGGCGGCATTGATTCGCGCTGCTTTGATGAGCGTTACCTGCGCGA
GCAAATCCGCGAAGTGGCGCCTGAAAAGGCCAATGCGGCACGTCCGTTCCGCCTGGCGATTATTCAGCTCGGTACCTACG
ACGGCACCATCTATAACGCCCGTCAGGTGATCGACACCATCGGCCACCTGTGTGACTACATTCTGTTTGACTCTGCCTGG
GTGGGGTACGAAGGTTTTATCCCGATGCTGAAAGAGTGCTCGCCGCTGTTGCTGGAGCTGGATGAGCTGGATCCGGGCAT
CTTTGTTACTCAGTCGGTGCATAAACAACAGGCTGGTTTCTCGCAGACTTCGCAAATCCACAAGAAAGACGACCACATCA
AGGGCCAGAAGCGCCACTGCAACCACAAGCACCTTAACAATGCTTTCATGCTGCACGCCTCTACCAGCCCGTTCTATCCA
CTGTTTGCCGCGCTGGACGTTAACGCCAAGATGCACGCCGGGGCTGCCGGTCGCCGCATGTGGCTGGACTGCGTGAAGCT
GGGTATCGAGACGCGCAAGCAACTGCTGGAACGCTGCTCGCAGCTCAGGCCGTTTATTCCGCCGCAGGTGGCGGGTAAAA
ACTGGCAGGATTACGACACCGATCTGATCGCCAACGACGCGCGTTTCTTCAATTTTGTGCCGGATGAAAAATGGCACGGT
TTTGAAGGTTACGCGCAGGATCAGTACCTGGTCGACCCGTGCAAGCTGCTGCTGACGACGCCGGGTATCGACGCGGCTAC
CGGCCAGTACACCGAGTTTGGCGTACCGGCGACTATTCTGGCCAACTTCCTGCGTGAGAACGGCATAGTGCCGGAGAAAT
GCGATCTTAACTCGATCCTGTTCCTGCTGACCCCGGCGGAAAATCCGGCCAAGATGGAACAGTTGGTGGATATGCTGGTG
CAGTTCGAACGCTATGTGGAAGAGGACGCGCCGCTGAGCGTGGTGCTGCCAACGGTGTATCGCAAGAATGAACAGCGCTA
TCGCGGCTATACCCTTCGCCAATTGTGCCAGGAAATGCATGACCTGTACGTCAGCTTTGACGTCAAACAGTTGCAGAAAG
AAATGTTCCGCCAGCGTCATTTCCCGCAGGTGATGATGAACCCACAGGATGCCAACGTGGAGTTTATCCGCGACAACGTT
GAACTGGTGCCGATTGGCCAGGCGGAAGGGCGCATTGCGGCGGAGGGCGCGCTGCCATACCCACCGGGCGTATTGTGCGT
GGTGCCGGGGGAAGTATGGGGCGGGGCGGTGCAGCGTTACTTCCTGGCGCTGGAAGAGGGTATCAACCGGCTACCGGGCT
TCTCGCCGGAGCTGCAGGGCGTGTATATCGAGAAAAAGGATCACGGCTGGAAACGTATCTTCGGTTATATGATCAAGCAA
TAG

Upstream 100 bases:

>100_bases
TGCGCTAACGCCGGACATCAATTTGCCGGGATAATTTTTGTTATCCCATCACCGTGCCCCGTGGCACCACCTCATCCTTA
ACCGTTTGAGAGTTAGCACA

Downstream 100 bases:

>100_bases
TCTTGGGCGGCCCGCAGGGGCCGTTTTTAAATCATCCCGGTCCGGGATGACAAAGCCGAGTGCTGGCGCTACCTTTAGGT
AAAAGTGTCCAGTAGCGGAA

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 720; Mature: 720

Protein sequence:

>720_residues
MKELKIATSASLVATIETLRQVVRIEQTDYTDVAALVVSVDDVNAGHLAQLKATGFEIPTFVAVAGDEHLSPDYLPLISG
VFALEGASKAFYMAQLEAAADAYEQALLPPFFKTLKTYVEMENSTFACPGHQGGEFFRKHPAGRKFFEFYGETLFRSDMC
NADVKLGDLLIHEGSAKDAQKHAARVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV
YLETARNPFGFIGGIDSRCFDERYLREQIREVAPEKANAARPFRLAIIQLGTYDGTIYNARQVIDTIGHLCDYILFDSAW
VGYEGFIPMLKECSPLLLELDELDPGIFVTQSVHKQQAGFSQTSQIHKKDDHIKGQKRHCNHKHLNNAFMLHASTSPFYP
LFAALDVNAKMHAGAAGRRMWLDCVKLGIETRKQLLERCSQLRPFIPPQVAGKNWQDYDTDLIANDARFFNFVPDEKWHG
FEGYAQDQYLVDPCKLLLTTPGIDAATGQYTEFGVPATILANFLRENGIVPEKCDLNSILFLLTPAENPAKMEQLVDMLV
QFERYVEEDAPLSVVLPTVYRKNEQRYRGYTLRQLCQEMHDLYVSFDVKQLQKEMFRQRHFPQVMMNPQDANVEFIRDNV
ELVPIGQAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGINRLPGFSPELQGVYIEKKDHGWKRIFGYMIKQ

Sequences:

>Translated_720_residues
MKELKIATSASLVATIETLRQVVRIEQTDYTDVAALVVSVDDVNAGHLAQLKATGFEIPTFVAVAGDEHLSPDYLPLISG
VFALEGASKAFYMAQLEAAADAYEQALLPPFFKTLKTYVEMENSTFACPGHQGGEFFRKHPAGRKFFEFYGETLFRSDMC
NADVKLGDLLIHEGSAKDAQKHAARVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV
YLETARNPFGFIGGIDSRCFDERYLREQIREVAPEKANAARPFRLAIIQLGTYDGTIYNARQVIDTIGHLCDYILFDSAW
VGYEGFIPMLKECSPLLLELDELDPGIFVTQSVHKQQAGFSQTSQIHKKDDHIKGQKRHCNHKHLNNAFMLHASTSPFYP
LFAALDVNAKMHAGAAGRRMWLDCVKLGIETRKQLLERCSQLRPFIPPQVAGKNWQDYDTDLIANDARFFNFVPDEKWHG
FEGYAQDQYLVDPCKLLLTTPGIDAATGQYTEFGVPATILANFLRENGIVPEKCDLNSILFLLTPAENPAKMEQLVDMLV
QFERYVEEDAPLSVVLPTVYRKNEQRYRGYTLRQLCQEMHDLYVSFDVKQLQKEMFRQRHFPQVMMNPQDANVEFIRDNV
ELVPIGQAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGINRLPGFSPELQGVYIEKKDHGWKRIFGYMIKQ
>Mature_720_residues
MKELKIATSASLVATIETLRQVVRIEQTDYTDVAALVVSVDDVNAGHLAQLKATGFEIPTFVAVAGDEHLSPDYLPLISG
VFALEGASKAFYMAQLEAAADAYEQALLPPFFKTLKTYVEMENSTFACPGHQGGEFFRKHPAGRKFFEFYGETLFRSDMC
NADVKLGDLLIHEGSAKDAQKHAARVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV
YLETARNPFGFIGGIDSRCFDERYLREQIREVAPEKANAARPFRLAIIQLGTYDGTIYNARQVIDTIGHLCDYILFDSAW
VGYEGFIPMLKECSPLLLELDELDPGIFVTQSVHKQQAGFSQTSQIHKKDDHIKGQKRHCNHKHLNNAFMLHASTSPFYP
LFAALDVNAKMHAGAAGRRMWLDCVKLGIETRKQLLERCSQLRPFIPPQVAGKNWQDYDTDLIANDARFFNFVPDEKWHG
FEGYAQDQYLVDPCKLLLTTPGIDAATGQYTEFGVPATILANFLRENGIVPEKCDLNSILFLLTPAENPAKMEQLVDMLV
QFERYVEEDAPLSVVLPTVYRKNEQRYRGYTLRQLCQEMHDLYVSFDVKQLQKEMFRQRHFPQVMMNPQDANVEFIRDNV
ELVPIGQAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGINRLPGFSPELQGVYIEKKDHGWKRIFGYMIKQ

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI87082193, Length=719, Percent_Identity=72.8789986091794, Blast_Score=1096, Evalue=0.0,
Organism=Escherichia coli, GI1786909, Length=719, Percent_Identity=69.6801112656467, Blast_Score=1063, Evalue=0.0,
Organism=Escherichia coli, GI221142684, Length=650, Percent_Identity=31.8461538461538, Blast_Score=328, Evalue=9e-91,
Organism=Escherichia coli, GI1790573, Length=612, Percent_Identity=33.8235294117647, Blast_Score=326, Evalue=3e-90,
Organism=Escherichia coli, GI1786384, Length=615, Percent_Identity=33.8211382113821, Blast_Score=317, Evalue=3e-87,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 80983; Mature: 80983

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELKIATSASLVATIETLRQVVRIEQTDYTDVAALVVSVDDVNAGHLAQLKATGFEIPT
CCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCE
FVAVAGDEHLSPDYLPLISGVFALEGASKAFYMAQLEAAADAYEQALLPPFFKTLKTYVE
EEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
MENSTFACPGHQGGEFFRKHPAGRKFFEFYGETLFRSDMCNADVKLGDLLIHEGSAKDAQ
CCCCEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEECEEEEECCCCHHHH
KHAARVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV
HHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPFGFIGGIDSRCFDERYLREQIREVAPEKANAARPFRLAIIQLGTYDGTIYNA
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCHHHH
RQVIDTIGHLCDYILFDSAWVGYEGFIPMLKECSPLLLELDELDPGIFVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHEEECCCCCCCEEEEHHHHHHHCCC
SQTSQIHKKDDHIKGQKRHCNHKHLNNAFMLHASTSPFYPLFAALDVNAKMHAGAAGRRM
HHHHHHHHHHHCCCCHHHCCCHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHH
WLDCVKLGIETRKQLLERCSQLRPFIPPQVAGKNWQDYDTDLIANDARFFNFVPDEKWHG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCEEECCCCCCCCC
FEGYAQDQYLVDPCKLLLTTPGIDAATGQYTEFGVPATILANFLRENGIVPEKCDLNSIL
CCCCCCCCEECCCHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAENPAKMEQLVDMLVQFERYVEEDAPLSVVLPTVYRKNEQRYRGYTLRQLCQEMH
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCHHHCCHHHHHHHHHHH
DLYVSFDVKQLQKEMFRQRHFPQVMMNPQDANVEFIRDNVELVPIGQAEGRIAAEGALPY
HHEECCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEECCCEEEECCCCCCCEEECCCCCC
PPGVLCVVPGEVWGGAVQRYFLALEEGINRLPGFSPELQGVYIEKKDHGWKRIFGYMIKQ
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCC
>Mature Secondary Structure
MKELKIATSASLVATIETLRQVVRIEQTDYTDVAALVVSVDDVNAGHLAQLKATGFEIPT
CCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCEEEEECCCCCCCE
FVAVAGDEHLSPDYLPLISGVFALEGASKAFYMAQLEAAADAYEQALLPPFFKTLKTYVE
EEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
MENSTFACPGHQGGEFFRKHPAGRKFFEFYGETLFRSDMCNADVKLGDLLIHEGSAKDAQ
CCCCEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCEECEEEEECCCCHHHH
KHAARVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQAGATPV
HHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEECCCCEE
YLETARNPFGFIGGIDSRCFDERYLREQIREVAPEKANAARPFRLAIIQLGTYDGTIYNA
EEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCHHHH
RQVIDTIGHLCDYILFDSAWVGYEGFIPMLKECSPLLLELDELDPGIFVTQSVHKQQAGF
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCHHEEECCCCCCCEEEEHHHHHHHCCC
SQTSQIHKKDDHIKGQKRHCNHKHLNNAFMLHASTSPFYPLFAALDVNAKMHAGAAGRRM
HHHHHHHHHHHCCCCHHHCCCHHHCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHH
WLDCVKLGIETRKQLLERCSQLRPFIPPQVAGKNWQDYDTDLIANDARFFNFVPDEKWHG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCEEECCCCCCCCC
FEGYAQDQYLVDPCKLLLTTPGIDAATGQYTEFGVPATILANFLRENGIVPEKCDLNSIL
CCCCCCCCEECCCHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
FLLTPAENPAKMEQLVDMLVQFERYVEEDAPLSVVLPTVYRKNEQRYRGYTLRQLCQEMH
EEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHCCCHHHCCHHHHHHHHHHH
DLYVSFDVKQLQKEMFRQRHFPQVMMNPQDANVEFIRDNVELVPIGQAEGRIAAEGALPY
HHEECCCHHHHHHHHHHHHCCCCEEECCCCCCEEEEECCCEEEECCCCCCCEEECCCCCC
PPGVLCVVPGEVWGGAVQRYFLALEEGINRLPGFSPELQGVYIEKKDHGWKRIFGYMIKQ
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]