Click here to switch to the map view.

The map label for this gene is cph2 [H]

Identifier: 157372280

GI number: 157372280

Start: 4482509

End: 4483621

Strand: Reverse

Name: cph2 [H]

Synonym: Spro_4046

Alternate gene names: 157372280

Gene position: 4483621-4482509 (Counterclockwise)

Preceding gene: 157372281

Following gene: 157372276

Centisome position: 82.29

GC content: 54.63

Gene sequence:

>1113_bases
ATGATGAAAGAAGAGGGTAATCTCGAGTGGGTCGGTAGAGAGAAGCGACGTTCGACGCTACGTAATTTTAACTGGTTCTT
ATTGGTTAATGTGCTGCTGGCGCTTTATCTGCTGTTTCAGCGTGCCCAAGCATTTGGCGAGCACTCTCTGATTTCTTTGT
TGCGTGGCGCACCGGCTATCTGCGGCGTGGTCTTGCTGTCTGTTCTGTCTTTTGTTGCGTTGCGTCAGTTGGCCGCCCGA
GGTGAACAGGCCGCCTGGCGTGGCGGGGTGGTTTGTATTTTGTTGTTGGCCCTGTGTTGGTGCGGCGTTTTTCACCATCT
GATCGTCAACGACAGTATTAATCTGCTTTACCCGTTAACCCTCGGCCTGCTGTTTTCTTCTCTGATCGCTTTTTATCTGT
CCCCGCGGCTATTTTTCCTGTTCAGCATTCCGGTGCTGCTGGTGGCGATTGCCGAAAATATCTTCATCAACAGCGCATTT
TCGCTGGTGAACCTGATCTCCTATGCGCTGATGCTGTTTTTGATTTATTCGGCGCGGAGCCGGCTGGAGCAGTGGTTCCA
ACTGGCGATCGAGCGCGAGCTGGAAAATAAGCAGCTGATTGAACGCCTGAGCAAGCTGGCCAACCGCGATCCGCTGACTG
GCATTGCCAACCGCCGCTACTTCGACAACTACTTTGATGCGGTTCTGTTGCGGGAATCAACCCTGCAGGCGCCGTTTTCC
CTGATCCTGCTGGACGTCGATTTTTTCAAAAAATACAACGACCACTATGGCCATCAGCAGGGGGACGAGTGCCTGACTCG
CTTGGCTACCTGCCTGGAGAGTGCCACCCGGCGTTCGCAGGATCTGGTGGCACGCTATGGTGGTGAGGAGTTTATTATTC
TGCTGCCAAAATCCGACGCAGGCGAAGCCGTGCAGGTGGCGAAGAGGATAGAAGGTTTGCTTGCCGGTCTGGCGATGCCG
CATGCGGCTTCTGAGGTAGCGCAATGGGTGACGGTCAGCCAGGGGGTAGCGCAATGGCAGCCGGGACAGAACCGTGAACA
ACTGCTGGCAGCAGCCGATCAGGCTCTGTACCGCGCCAAGGAGCTTGGCCGTAATGGCTACAGTATTGCTTAA

Upstream 100 bases:

>100_bases
GGGCGGCCCGCAGGGGCCGTTTTTAAATCATCCCGGTCCGGGATGACAAAGCCGAGTGCTGGCGCTACCTTTAGGTAAAA
GTGTCCAGTAGCGGAATAAG

Downstream 100 bases:

>100_bases
GGATGCTGGTGGTCAGGGCGACGGGAAAGACCGCCCTGACCGGGTGATTAACGGCGTCGATAGCTCTTCTGCGCGTTGTT
CACCTTCACCAGATAGTGGC

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MMKEEGNLEWVGREKRRSTLRNFNWFLLVNVLLALYLLFQRAQAFGEHSLISLLRGAPAICGVVLLSVLSFVALRQLAAR
GEQAAWRGGVVCILLLALCWCGVFHHLIVNDSINLLYPLTLGLLFSSLIAFYLSPRLFFLFSIPVLLVAIAENIFINSAF
SLVNLISYALMLFLIYSARSRLEQWFQLAIERELENKQLIERLSKLANRDPLTGIANRRYFDNYFDAVLLRESTLQAPFS
LILLDVDFFKKYNDHYGHQQGDECLTRLATCLESATRRSQDLVARYGGEEFIILLPKSDAGEAVQVAKRIEGLLAGLAMP
HAASEVAQWVTVSQGVAQWQPGQNREQLLAAADQALYRAKELGRNGYSIA

Sequences:

>Translated_370_residues
MMKEEGNLEWVGREKRRSTLRNFNWFLLVNVLLALYLLFQRAQAFGEHSLISLLRGAPAICGVVLLSVLSFVALRQLAAR
GEQAAWRGGVVCILLLALCWCGVFHHLIVNDSINLLYPLTLGLLFSSLIAFYLSPRLFFLFSIPVLLVAIAENIFINSAF
SLVNLISYALMLFLIYSARSRLEQWFQLAIERELENKQLIERLSKLANRDPLTGIANRRYFDNYFDAVLLRESTLQAPFS
LILLDVDFFKKYNDHYGHQQGDECLTRLATCLESATRRSQDLVARYGGEEFIILLPKSDAGEAVQVAKRIEGLLAGLAMP
HAASEVAQWVTVSQGVAQWQPGQNREQLLAAADQALYRAKELGRNGYSIA
>Mature_370_residues
MMKEEGNLEWVGREKRRSTLRNFNWFLLVNVLLALYLLFQRAQAFGEHSLISLLRGAPAICGVVLLSVLSFVALRQLAAR
GEQAAWRGGVVCILLLALCWCGVFHHLIVNDSINLLYPLTLGLLFSSLIAFYLSPRLFFLFSIPVLLVAIAENIFINSAF
SLVNLISYALMLFLIYSARSRLEQWFQLAIERELENKQLIERLSKLANRDPLTGIANRRYFDNYFDAVLLRESTLQAPFS
LILLDVDFFKKYNDHYGHQQGDECLTRLATCLESATRRSQDLVARYGGEEFIILLPKSDAGEAVQVAKRIEGLLAGLAMP
HAASEVAQWVTVSQGVAQWQPGQNREQLLAAADQALYRAKELGRNGYSIA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=171, Percent_Identity=40.3508771929825, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=37.9518072289157, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=39.8773006134969, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI145693134, Length=170, Percent_Identity=34.7058823529412, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1786584, Length=287, Percent_Identity=28.9198606271777, Blast_Score=98, Evalue=9e-22,
Organism=Escherichia coli, GI87082007, Length=134, Percent_Identity=42.5373134328358, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788085, Length=167, Percent_Identity=32.9341317365269, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1787541, Length=176, Percent_Identity=31.25, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1788381, Length=184, Percent_Identity=30.9782608695652, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787802, Length=174, Percent_Identity=29.3103448275862, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87081974, Length=164, Percent_Identity=29.2682926829268, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787056, Length=155, Percent_Identity=30.3225806451613, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 41688; Mature: 41688

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKEEGNLEWVGREKRRSTLRNFNWFLLVNVLLALYLLFQRAQAFGEHSLISLLRGAPAI
CCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHH
CGVVLLSVLSFVALRQLAARGEQAAWRGGVVCILLLALCWCGVFHHLIVNDSINLLYPLT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LGLLFSSLIAFYLSPRLFFLFSIPVLLVAIAENIFINSAFSLVNLISYALMLFLIYSARS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLEQWFQLAIERELENKQLIERLSKLANRDPLTGIANRRYFDNYFDAVLLRESTLQAPFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
LILLDVDFFKKYNDHYGHQQGDECLTRLATCLESATRRSQDLVARYGGEEFIILLPKSDA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
GEAVQVAKRIEGLLAGLAMPHAASEVAQWVTVSQGVAQWQPGQNREQLLAAADQALYRAK
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ELGRNGYSIA
HHCCCCCCCC
>Mature Secondary Structure
MMKEEGNLEWVGREKRRSTLRNFNWFLLVNVLLALYLLFQRAQAFGEHSLISLLRGAPAI
CCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCHHH
CGVVLLSVLSFVALRQLAARGEQAAWRGGVVCILLLALCWCGVFHHLIVNDSINLLYPLT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
LGLLFSSLIAFYLSPRLFFLFSIPVLLVAIAENIFINSAFSLVNLISYALMLFLIYSARS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLEQWFQLAIERELENKQLIERLSKLANRDPLTGIANRRYFDNYFDAVLLRESTLQAPFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
LILLDVDFFKKYNDHYGHQQGDECLTRLATCLESATRRSQDLVARYGGEEFIILLPKSDA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCC
GEAVQVAKRIEGLLAGLAMPHAASEVAQWVTVSQGVAQWQPGQNREQLLAAADQALYRAK
CHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
ELGRNGYSIA
HHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]