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The map label for this gene is yggW [H]

Identifier: 157372269

GI number: 157372269

Start: 4474777

End: 4475916

Strand: Direct

Name: yggW [H]

Synonym: Spro_4035

Alternate gene names: 157372269

Gene position: 4474777-4475916 (Clockwise)

Preceding gene: 157372268

Following gene: 157372277

Centisome position: 82.12

GC content: 59.82

Gene sequence:

>1140_bases
ATGCTTAAGTTGCCTCCGCTGAGTTTGTACATCCATATCCCGTGGTGCGTGCAGAAATGCCCGTACTGCGACTTCAACTC
GCATGCGTTAAAGGGCGAAGTCCCGCATCAGGAATATGTTGATCACCTGCTGGCGGATCTGGATGCCGATCTGCCGCTGG
TGGCCGGCCGGGAAGTCAGTACCATTTTTATCGGCGGCGGCACCCCCAGCCTGCTGAGTGCCGAGGCGATGCAATCGCTG
CTGGACGGCGTGCGGGCGCGCATTCACGTCGTTGATGGCGCAGAGATCACCATGGAGGCCAACCCCGGCACCGTGGAAGC
CGATCGCTTCAGCGGCTATCAGCGGGCCGGTGTGAACCGCATTTCTATCGGGGTGCAGAGCTTCAGCGCCGAGAAGTTAA
CCCGTCTGGGGCGCATTCACGGCCCGGAAGAGGCCAAACGCGCAGCGCATCTGGCCACCGGTCTTGGCCTGCGCAGCTTT
AACCTCGATCTGATGCACGGCCTGCCGGACCAGTCGCTGGAAGAGGCGCTGGACGATTTACGCCAGGCGATTGCCCTGAA
CCCGCCGCACCTGTCGTGGTATCAGCTGACCATCGAACCCAATACCCTGTTCAGCTCACGCCCGCCGGTACTGCCGGACG
ACGATGCGCTGTGGGATATTTTCGAACGCGGTCATGAGTTGCTGAGCGCCGCCGGCTATCAGCAGTATGAAACTTCGGCC
TATGCCAAGCCGGGCTATCAGTGCCAGCACAACCTCAACTACTGGCGCTTTGGCGACTATCTGGGGATTGGCTGTGGCGC
ACACGGTAAACTGACCTTCAGCGACGGCCGCATTCTGCGCACCGCGAAAACCAAGCATCCGCGCGGTTTTATGCAGGGCA
AGTATATGGACAAGCAGCATGAGGTGACGACGGCGGATCGGCCGTTCGAGTTCTTTATGAACCGTTTCCGCCTGCTGGAG
GCCGCGCCGCGCGCCGAGTTCGTCAACTACACCGGGCTGGATGAAAGCACTATCCGCGCACCGCTGGATGAAGCACTGGC
GAAAGGTTATCTGGAAGAGACGCCGGAATATTGGCAGATCACCGAGAAGGGCAAGCTGTTCCTTAACTCGTTGCTGGAGC
TGTTTCTGGCGGATGAATAG

Upstream 100 bases:

>100_bases
CCGGAACTGGGCCGCACCGCCGCCGAACTGAGCCGCGACGAAAAACGCGCGATATCGCACCGTGGCAAGGCGCTGAAACT
GATGCTGGAAGCCATGCGTA

Downstream 100 bases:

>100_bases
CAAAAAGCGCTGAATTATCAGCGCTTTTTTTGGTTTCAATCTGGATAGAACTCGTGGGAAAGCACCTGCTGGATATCCCA
AATCCCGTTTTCCGGATAAA

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MLKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHQEYVDHLLADLDADLPLVAGREVSTIFIGGGTPSLLSAEAMQSL
LDGVRARIHVVDGAEITMEANPGTVEADRFSGYQRAGVNRISIGVQSFSAEKLTRLGRIHGPEEAKRAAHLATGLGLRSF
NLDLMHGLPDQSLEEALDDLRQAIALNPPHLSWYQLTIEPNTLFSSRPPVLPDDDALWDIFERGHELLSAAGYQQYETSA
YAKPGYQCQHNLNYWRFGDYLGIGCGAHGKLTFSDGRILRTAKTKHPRGFMQGKYMDKQHEVTTADRPFEFFMNRFRLLE
AAPRAEFVNYTGLDESTIRAPLDEALAKGYLEETPEYWQITEKGKLFLNSLLELFLADE

Sequences:

>Translated_379_residues
MLKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHQEYVDHLLADLDADLPLVAGREVSTIFIGGGTPSLLSAEAMQSL
LDGVRARIHVVDGAEITMEANPGTVEADRFSGYQRAGVNRISIGVQSFSAEKLTRLGRIHGPEEAKRAAHLATGLGLRSF
NLDLMHGLPDQSLEEALDDLRQAIALNPPHLSWYQLTIEPNTLFSSRPPVLPDDDALWDIFERGHELLSAAGYQQYETSA
YAKPGYQCQHNLNYWRFGDYLGIGCGAHGKLTFSDGRILRTAKTKHPRGFMQGKYMDKQHEVTTADRPFEFFMNRFRLLE
AAPRAEFVNYTGLDESTIRAPLDEALAKGYLEETPEYWQITEKGKLFLNSLLELFLADE
>Mature_379_residues
MLKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHQEYVDHLLADLDADLPLVAGREVSTIFIGGGTPSLLSAEAMQSL
LDGVRARIHVVDGAEITMEANPGTVEADRFSGYQRAGVNRISIGVQSFSAEKLTRLGRIHGPEEAKRAAHLATGLGLRSF
NLDLMHGLPDQSLEEALDDLRQAIALNPPHLSWYQLTIEPNTLFSSRPPVLPDDDALWDIFERGHELLSAAGYQQYETSA
YAKPGYQCQHNLNYWRFGDYLGIGCGAHGKLTFSDGRILRTAKTKHPRGFMQGKYMDKQHEVTTADRPFEFFMNRFRLLE
AAPRAEFVNYTGLDESTIRAPLDEALAKGYLEETPEYWQITEKGKLFLNSLLELFLADE

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=268, Percent_Identity=36.5671641791045, Blast_Score=167, Evalue=1e-41,
Organism=Escherichia coli, GI1789325, Length=378, Percent_Identity=82.8042328042328, Blast_Score=662, Evalue=0.0,
Organism=Escherichia coli, GI87082341, Length=243, Percent_Identity=32.0987654320988, Blast_Score=128, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42493; Mature: 42493

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHQEYVDHLLADLDADLPLVAGREVS
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCEE
TIFIGGGTPSLLSAEAMQSLLDGVRARIHVVDGAEITMEANPGTVEADRFSGYQRAGVNR
EEEECCCCCHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCCCEEEHHHHCCHHHCCCCE
ISIGVQSFSAEKLTRLGRIHGPEEAKRAAHLATGLGLRSFNLDLMHGLPDQSLEEALDDL
EEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECHHHHCCCCCHHHHHHHHHH
RQAIALNPPHLSWYQLTIEPNTLFSSRPPVLPDDDALWDIFERGHELLSAAGYQQYETSA
HHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCC
YAKPGYQCQHNLNYWRFGDYLGIGCGAHGKLTFSDGRILRTAKTKHPRGFMQGKYMDKQH
CCCCCCCCCCCCCEEEECCEEEECCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCC
EVTTADRPFEFFMNRFRLLEAAPRAEFVNYTGLDESTIRAPLDEALAKGYLEETPEYWQI
CCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCEEE
TEKGKLFLNSLLELFLADE
CHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHQEYVDHLLADLDADLPLVAGREVS
CCCCCCEEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECCCEE
TIFIGGGTPSLLSAEAMQSLLDGVRARIHVVDGAEITMEANPGTVEADRFSGYQRAGVNR
EEEECCCCCHHHHHHHHHHHHHHHHEEEEEECCCEEEEECCCCEEEHHHHCCHHHCCCCE
ISIGVQSFSAEKLTRLGRIHGPEEAKRAAHLATGLGLRSFNLDLMHGLPDQSLEEALDDL
EEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECHHHHCCCCCHHHHHHHHHH
RQAIALNPPHLSWYQLTIEPNTLFSSRPPVLPDDDALWDIFERGHELLSAAGYQQYETSA
HHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHCC
YAKPGYQCQHNLNYWRFGDYLGIGCGAHGKLTFSDGRILRTAKTKHPRGFMQGKYMDKQH
CCCCCCCCCCCCCEEEECCEEEECCCCCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCC
EVTTADRPFEFFMNRFRLLEAAPRAEFVNYTGLDESTIRAPLDEALAKGYLEETPEYWQI
CCCCCCCCHHHHHHHHHHHHHCCCHHCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCEEE
TEKGKLFLNSLLELFLADE
CHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]