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The map label for this gene is qseC [H]

Identifier: 157372223

GI number: 157372223

Start: 4424331

End: 4425689

Strand: Reverse

Name: qseC [H]

Synonym: Spro_3989

Alternate gene names: 157372223

Gene position: 4425689-4424331 (Counterclockwise)

Preceding gene: 157372224

Following gene: 157372216

Centisome position: 81.22

GC content: 61.07

Gene sequence:

>1359_bases
GTGAAACATCTTAGTTTGCGGCTGCGGCTGATCCTGATTTTCAGCCTGCTGGCGTTATTGACCTGGTGCGCTGCCAGCCT
GGTGGCCTGGAAGATGAGCCGCAATACCATCAACGAAGTCTTCGATACCCAGCAGATGCTGTTTGCCAAACGGCTGGCAA
CCGCCAATCTGGGCGATCTGTTGGCAGACGAGAGCGTGCGCAGTCTGCCGAAAACCAAAAAACTGGTGCATCACGGCAAG
CGTGGCGAGCAGGATGATGATGCGCTGGCGTTCGCCATCTTCGACCGCAGCGGCAAGATGCTGCTCAACGACGGGGAGAA
CGGGGCGGATTTCCGTTTTGACGGCGACCGTGAAGGTTTCACCGACGGAGAACGTAAGGGCGATGACGACAGTTGGCGGC
TGCTGTGGCTGACCAGCCCGGATGGCCGTTATCGCATCGTGGTGGGGCAGGAGTGGGATTATCGCCGGGATATGGCGCTG
GGCATGGTAACCGGGCAACTGGTGCCGTGGCTGGTGACGCTGCCGATACTGATGCTGCTGATTGCGCTGATGGTCGGGCG
CGAGCTGCGGCCATTACGCACCGTCGCTGCCGGACTACGTAAACGCGCACCGGACGATGCCACGCCGCTGGATGCCGGTC
AGGTACCGACCGAAGTCCGGCCATTGGTCGATGCGCTTAATGCTCTGTTTGCCCGAATCAATGCGCTGTTGGTGCGTGAA
CGCCGTTTTACTTCTGACGCCGCCCACGAACTGCGTAGCCCGTTGGCGGCGCTGCGGGTGCAAACGGAAGTGGTACAACT
GGCCGGTGATGACGAACAGATGCGTGAGCATGCGCTGGGCAATCTGACGGTAGGTATCGATCGCGCCACCCGGCTGGTGG
ATCAACTGCTGACGCTGTCGCGGTTGGATTCCCTGTCAGACCTCGCCGAGCTGGAAGCTGCCGACTGGAGCCAACTGGTA
CCGATGACGTTGGCCGAGCAGGATCGCCATGCTCATGCGGCCGGCGTCACGCTACGTTACGAACAGCAGGGGATGCCACC
ACCGTTACAGGGGCAAGCGTTGCTGCTGTCGCTGCTGGTGCGCAACCTGGTGGATAATGCGGTGCGTTACACCCCGACGG
GCGGTACGGTCACGGTGAGGCTGACAGAGCGTCTGTTGACGGTGGTAGACGATGGCCCGGGCGTGACGACGGAACATCTG
GCGCGGTTGGGGGAGCGTTTTTATCGTCCACCGGGTCAGGAACAGACCGGTAGCGGGTTGGGGTTGTCAATTGTGCAACG
CATTGCCGGTTTACACGGGCTGCGGGTTAGCTTCGCCAATCGGCCTGAAGGGGGCTTTGTTGCTCAGGTAGCGCTGTAG

Upstream 100 bases:

>100_bases
GCAACGCGGTGGAGGTGCATATCCATCATCTGCGGCGCAAGCTGGGTAACGGGTTTATCCGCACCATACACGGCGTGGGT
TATACGCTGGGGGACAACGC

Downstream 100 bases:

>100_bases
GGGCGTTCTGTATATCCTGCGCCGACTCAGACTTTTTGCCTGGGTTGGTGCCAAAGCTCCATGCCGTTTTGCGGTACGCG
CTTCAGGCAGCTGACCAGCG

Product: sensor protein QseC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKHLSLRLRLILIFSLLALLTWCAASLVAWKMSRNTINEVFDTQQMLFAKRLATANLGDLLADESVRSLPKTKKLVHHGK
RGEQDDDALAFAIFDRSGKMLLNDGENGADFRFDGDREGFTDGERKGDDDSWRLLWLTSPDGRYRIVVGQEWDYRRDMAL
GMVTGQLVPWLVTLPILMLLIALMVGRELRPLRTVAAGLRKRAPDDATPLDAGQVPTEVRPLVDALNALFARINALLVRE
RRFTSDAAHELRSPLAALRVQTEVVQLAGDDEQMREHALGNLTVGIDRATRLVDQLLTLSRLDSLSDLAELEAADWSQLV
PMTLAEQDRHAHAAGVTLRYEQQGMPPPLQGQALLLSLLVRNLVDNAVRYTPTGGTVTVRLTERLLTVVDDGPGVTTEHL
ARLGERFYRPPGQEQTGSGLGLSIVQRIAGLHGLRVSFANRPEGGFVAQVAL

Sequences:

>Translated_452_residues
MKHLSLRLRLILIFSLLALLTWCAASLVAWKMSRNTINEVFDTQQMLFAKRLATANLGDLLADESVRSLPKTKKLVHHGK
RGEQDDDALAFAIFDRSGKMLLNDGENGADFRFDGDREGFTDGERKGDDDSWRLLWLTSPDGRYRIVVGQEWDYRRDMAL
GMVTGQLVPWLVTLPILMLLIALMVGRELRPLRTVAAGLRKRAPDDATPLDAGQVPTEVRPLVDALNALFARINALLVRE
RRFTSDAAHELRSPLAALRVQTEVVQLAGDDEQMREHALGNLTVGIDRATRLVDQLLTLSRLDSLSDLAELEAADWSQLV
PMTLAEQDRHAHAAGVTLRYEQQGMPPPLQGQALLLSLLVRNLVDNAVRYTPTGGTVTVRLTERLLTVVDDGPGVTTEHL
ARLGERFYRPPGQEQTGSGLGLSIVQRIAGLHGLRVSFANRPEGGFVAQVAL
>Mature_452_residues
MKHLSLRLRLILIFSLLALLTWCAASLVAWKMSRNTINEVFDTQQMLFAKRLATANLGDLLADESVRSLPKTKKLVHHGK
RGEQDDDALAFAIFDRSGKMLLNDGENGADFRFDGDREGFTDGERKGDDDSWRLLWLTSPDGRYRIVVGQEWDYRRDMAL
GMVTGQLVPWLVTLPILMLLIALMVGRELRPLRTVAAGLRKRAPDDATPLDAGQVPTEVRPLVDALNALFARINALLVRE
RRFTSDAAHELRSPLAALRVQTEVVQLAGDDEQMREHALGNLTVGIDRATRLVDQLLTLSRLDSLSDLAELEAADWSQLV
PMTLAEQDRHAHAAGVTLRYEQQGMPPPLQGQALLLSLLVRNLVDNAVRYTPTGGTVTVRLTERLLTVVDDGPGVTTEHL
ARLGERFYRPPGQEQTGSGLGLSIVQRIAGLHGLRVSFANRPEGGFVAQVAL

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=450, Percent_Identity=56.8888888888889, Blast_Score=480, Evalue=1e-137,
Organism=Escherichia coli, GI1790551, Length=293, Percent_Identity=31.740614334471, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786783, Length=335, Percent_Identity=28.3582089552239, Blast_Score=118, Evalue=7e-28,
Organism=Escherichia coli, GI1786600, Length=210, Percent_Identity=34.7619047619048, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1788393, Length=273, Percent_Identity=29.6703296703297, Blast_Score=92, Evalue=5e-20,
Organism=Escherichia coli, GI1788279, Length=297, Percent_Identity=26.2626262626263, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1790861, Length=248, Percent_Identity=31.4516129032258, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790346, Length=257, Percent_Identity=28.4046692607004, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787894, Length=227, Percent_Identity=29.9559471365639, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI87082128, Length=281, Percent_Identity=24.1992882562278, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 50031; Mature: 50031

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHLSLRLRLILIFSLLALLTWCAASLVAWKMSRNTINEVFDTQQMLFAKRLATANLGDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LADESVRSLPKTKKLVHHGKRGEQDDDALAFAIFDRSGKMLLNDGENGADFRFDGDREGF
HHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEECCCCCCC
TDGERKGDDDSWRLLWLTSPDGRYRIVVGQEWDYRRDMALGMVTGQLVPWLVTLPILMLL
CCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IALMVGRELRPLRTVAAGLRKRAPDDATPLDAGQVPTEVRPLVDALNALFARINALLVRE
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRFTSDAAHELRSPLAALRVQTEVVQLAGDDEQMREHALGNLTVGIDRATRLVDQLLTLS
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
RLDSLSDLAELEAADWSQLVPMTLAEQDRHAHAAGVTLRYEQQGMPPPLQGQALLLSLLV
HHHHHHHHHHHHHCCHHHHCCHHHHHCCCCHHHHCCEEEECCCCCCCCCCHHHHHHHHHH
RNLVDNAVRYTPTGGTVTVRLTERLLTVVDDGPGVTTEHLARLGERFYRPPGQEQTGSGL
HHHHHHCEEECCCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GLSIVQRIAGLHGLRVSFANRPEGGFVAQVAL
CHHHHHHHHCCCCEEEEECCCCCCCEEEEEEC
>Mature Secondary Structure
MKHLSLRLRLILIFSLLALLTWCAASLVAWKMSRNTINEVFDTQQMLFAKRLATANLGDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
LADESVRSLPKTKKLVHHGKRGEQDDDALAFAIFDRSGKMLLNDGENGADFRFDGDREGF
HHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCEECCCCCCC
TDGERKGDDDSWRLLWLTSPDGRYRIVVGQEWDYRRDMALGMVTGQLVPWLVTLPILMLL
CCCCCCCCCCCEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IALMVGRELRPLRTVAAGLRKRAPDDATPLDAGQVPTEVRPLVDALNALFARINALLVRE
HHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RRFTSDAAHELRSPLAALRVQTEVVQLAGDDEQMREHALGNLTVGIDRATRLVDQLLTLS
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
RLDSLSDLAELEAADWSQLVPMTLAEQDRHAHAAGVTLRYEQQGMPPPLQGQALLLSLLV
HHHHHHHHHHHHHCCHHHHCCHHHHHCCCCHHHHCCEEEECCCCCCCCCCHHHHHHHHHH
RNLVDNAVRYTPTGGTVTVRLTERLLTVVDDGPGVTTEHLARLGERFYRPPGQEQTGSGL
HHHHHHCEEECCCCCEEEEEEHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCC
GLSIVQRIAGLHGLRVSFANRPEGGFVAQVAL
CHHHHHHHHCCCCEEEEECCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]