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The map label for this gene is qseB [H]

Identifier: 157372224

GI number: 157372224

Start: 4425686

End: 4426348

Strand: Reverse

Name: qseB [H]

Synonym: Spro_3990

Alternate gene names: 157372224

Gene position: 4426348-4425686 (Counterclockwise)

Preceding gene: 157372228

Following gene: 157372223

Centisome position: 81.23

GC content: 59.28

Gene sequence:

>663_bases
ATGCGAATTCTGCTGATAGAAGATGACAAGTTAATCGGCGACGGTATCAAGGCCGGGCTGACCAGGTTGGGTTTTAATCT
GGACTGGTTTACCGATGGACTGGTCGGCAAAAATGCGCTGGAAAGCGCGCCTTACGATGCGGTGATCCTCGACTTGAGCC
TGCCGGGCCTCGATGGCCTGGATCTGTTGCGTCAGTGGCGGCAGGCCGGCCATGACGTGCCGGTGCTGATCCTGACCGCG
CGTGACGCACTGGAGCAACGGGTTAGCGGCCTGCAAAGCGGTGCCGATGATTACCTGTGCAAACCTTTTGCCCTGACGGA
GGTAGCGGCGCGCCTGCAGGCCTTGATTCGCCGTCGTCACGGCCAACTGATGCCGCAACTGGTCCATGGCAATGTGGTGT
TCGATACCGCAACCCGCAGCGTGAGCTGTAACGGTGAGCCGGTCACGCTGACCCCGCGTGAATTGGCGGTGCTGGAGCTG
TTTTTGCATAACAAGGGGCGGGTATTGGCACGGCCGCTGATCCAGGAAAAACTGTACAACTGGGACGACGAAGTCAGCAG
CAACGCGGTGGAGGTGCATATCCATCATCTGCGGCGCAAGCTGGGTAACGGGTTTATCCGCACCATACACGGCGTGGGTT
ATACGCTGGGGGACAACGCGTGA

Upstream 100 bases:

>100_bases
ACTGTAACCCTAACGGGGTGGGTAGCGCAGATCATAATGCTTAAGCGGTTCTTAAGAACCTTGTGGTGTAATGGGCGGCA
ATGGCTAAAAAAGGACGCAC

Downstream 100 bases:

>100_bases
AACATCTTAGTTTGCGGCTGCGGCTGATCCTGATTTTCAGCCTGCTGGCGTTATTGACCTGGTGCGCTGCCAGCCTGGTG
GCCTGGAAGATGAGCCGCAA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 220; Mature: 220

Protein sequence:

>220_residues
MRILLIEDDKLIGDGIKAGLTRLGFNLDWFTDGLVGKNALESAPYDAVILDLSLPGLDGLDLLRQWRQAGHDVPVLILTA
RDALEQRVSGLQSGADDYLCKPFALTEVAARLQALIRRRHGQLMPQLVHGNVVFDTATRSVSCNGEPVTLTPRELAVLEL
FLHNKGRVLARPLIQEKLYNWDDEVSSNAVEVHIHHLRRKLGNGFIRTIHGVGYTLGDNA

Sequences:

>Translated_220_residues
MRILLIEDDKLIGDGIKAGLTRLGFNLDWFTDGLVGKNALESAPYDAVILDLSLPGLDGLDLLRQWRQAGHDVPVLILTA
RDALEQRVSGLQSGADDYLCKPFALTEVAARLQALIRRRHGQLMPQLVHGNVVFDTATRSVSCNGEPVTLTPRELAVLEL
FLHNKGRVLARPLIQEKLYNWDDEVSSNAVEVHIHHLRRKLGNGFIRTIHGVGYTLGDNA
>Mature_220_residues
MRILLIEDDKLIGDGIKAGLTRLGFNLDWFTDGLVGKNALESAPYDAVILDLSLPGLDGLDLLRQWRQAGHDVPVLILTA
RDALEQRVSGLQSGADDYLCKPFALTEVAARLQALIRRRHGQLMPQLVHGNVVFDTATRSVSCNGEPVTLTPRELAVLEL
FLHNKGRVLARPLIQEKLYNWDDEVSSNAVEVHIHHLRRKLGNGFIRTIHGVGYTLGDNA

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. Currently it is not known whether this effect is direct or not [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=68.4931506849315, Blast_Score=318, Evalue=2e-88,
Organism=Escherichia coli, GI1790552, Length=219, Percent_Identity=43.8356164383562, Blast_Score=186, Evalue=8e-49,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=39.3665158371041, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=36.8181818181818, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=33.9449541284404, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=34.0909090909091, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=30.9417040358744, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=32.579185520362, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=33.7837837837838, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=29.4372294372294, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=32.8947368421053, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1787229, Length=223, Percent_Identity=28.6995515695067, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI1790863, Length=226, Percent_Identity=27.8761061946903, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1790299, Length=129, Percent_Identity=34.8837209302326, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=30.5785123966942, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788550, Length=152, Percent_Identity=26.3157894736842, Blast_Score=61, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=156, Percent_Identity=27.5641025641026, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24368; Mature: 24368

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLIEDDKLIGDGIKAGLTRLGFNLDWFTDGLVGKNALESAPYDAVILDLSLPGLDGL
CEEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHCCCCCEEEEEEECCCCCHH
DLLRQWRQAGHDVPVLILTARDALEQRVSGLQSGADDYLCKPFALTEVAARLQALIRRRH
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GQLMPQLVHGNVVFDTATRSVSCNGEPVTLTPRELAVLELFLHNKGRVLARPLIQEKLYN
HHHHHHHHCCCEEEECCCCEEECCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
WDDEVSSNAVEVHIHHLRRKLGNGFIRTIHGVGYTLGDNA
CCCHHCCCHHHHHHHHHHHHHCCCCEEHHHHCCEECCCCC
>Mature Secondary Structure
MRILLIEDDKLIGDGIKAGLTRLGFNLDWFTDGLVGKNALESAPYDAVILDLSLPGLDGL
CEEEEEECCCHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHCCCCCEEEEEEECCCCCHH
DLLRQWRQAGHDVPVLILTARDALEQRVSGLQSGADDYLCKPFALTEVAARLQALIRRRH
HHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
GQLMPQLVHGNVVFDTATRSVSCNGEPVTLTPRELAVLELFLHNKGRVLARPLIQEKLYN
HHHHHHHHCCCEEEECCCCEEECCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
WDDEVSSNAVEVHIHHLRRKLGNGFIRTIHGVGYTLGDNA
CCCHHCCCHHHHHHHHHHHHHCCCCEEHHHHCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]