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The map label for this gene is sgbE [H]

Identifier: 157372173

GI number: 157372173

Start: 4363456

End: 4364157

Strand: Direct

Name: sgbE [H]

Synonym: Spro_3939

Alternate gene names: 157372173

Gene position: 4363456-4364157 (Clockwise)

Preceding gene: 157372172

Following gene: 157372174

Centisome position: 80.08

GC content: 60.26

Gene sequence:

>702_bases
ATGCTAACGCTGTCGCAGCTGAAACAACAGGTACTGGAAGCCAACCTCGACCTGCCGCGCCATAACCTGGTGACCTTCAC
CTGGGGCAACGTCAGCGCGGTGGATCGCGAACGCGGGCTGGTGGTGATCAAGCCTTCCGGCGTGGAATATGAACACATGG
TGGCCGAGGACATGGTGGTGGTCAGCCTCGCCAGTGGCCAAACCGTCGAGGGCAGCAAAAAGCCCTCCTCGGACACCGCC
ACCCATCTGGCGCTGTACCGTGAATTTGCCGATATCGGCGGCATCGTACACACCCATTCGCGCCACGCCACCATCTGGGC
GCAGGCCGGGCTGGACATCCCCGCCTGGGGCACTACCCACGCCGATTATTTCTACGGTGCCATTCCCTGCACCCGGCTGA
TGACCGAGGACGAAATTGCGCAAGATTACGAACTGGAGACCGGCAAGGTGATTATCGACACCTTCCACCGACGCGGTATC
AGCCCGAACGCCATTCCGGCGGTGCTGGTCAATTCACACGGCCCCTTCGCCTGGGGCAAGGACGCGCACAGCGCGGTACA
CAACGCGGTAGTGCTGGAAGAAATTGCCTATATGGGGATTTTCTCGCGCCAGTTGACGCCGGGCATCAGCAGCATGCAGC
CCGCGCTGCTGGATAAACACTACCTGCGCAAACACGGCAAGAATGCTTATTACGGGCAATAA

Upstream 100 bases:

>100_bases
TCCTGATCGAGATGTGGACCGAGAAAGCCGAAGAGCCGGTGGCAGAAATCGTACAGGCACGCCGCTGGATCGAACAAAAA
ATGCAACAAGGGGGTATGAC

Downstream 100 bases:

>100_bases
ATAGGGTTGGCGGGCCTCAGTTCCAGTATCAAAAGTTTTCACCGGATGCTTTGAGGCATCTGGTGAAAACAAAGTTAGCT
GGCATGGAAATCAGCCTTCT

Product: L-ribulose-5-phosphate 4-epimerase

Products: NA

Alternate protein names: Phosphoribulose isomerase [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MLTLSQLKQQVLEANLDLPRHNLVTFTWGNVSAVDRERGLVVIKPSGVEYEHMVAEDMVVVSLASGQTVEGSKKPSSDTA
THLALYREFADIGGIVHTHSRHATIWAQAGLDIPAWGTTHADYFYGAIPCTRLMTEDEIAQDYELETGKVIIDTFHRRGI
SPNAIPAVLVNSHGPFAWGKDAHSAVHNAVVLEEIAYMGIFSRQLTPGISSMQPALLDKHYLRKHGKNAYYGQ

Sequences:

>Translated_233_residues
MLTLSQLKQQVLEANLDLPRHNLVTFTWGNVSAVDRERGLVVIKPSGVEYEHMVAEDMVVVSLASGQTVEGSKKPSSDTA
THLALYREFADIGGIVHTHSRHATIWAQAGLDIPAWGTTHADYFYGAIPCTRLMTEDEIAQDYELETGKVIIDTFHRRGI
SPNAIPAVLVNSHGPFAWGKDAHSAVHNAVVLEEIAYMGIFSRQLTPGISSMQPALLDKHYLRKHGKNAYYGQ
>Mature_233_residues
MLTLSQLKQQVLEANLDLPRHNLVTFTWGNVSAVDRERGLVVIKPSGVEYEHMVAEDMVVVSLASGQTVEGSKKPSSDTA
THLALYREFADIGGIVHTHSRHATIWAQAGLDIPAWGTTHADYFYGAIPCTRLMTEDEIAQDYELETGKVIIDTFHRRGI
SPNAIPAVLVNSHGPFAWGKDAHSAVHNAVVLEEIAYMGIFSRQLTPGISSMQPALLDKHYLRKHGKNAYYGQ

Specific function: Catalyzes the isomerization of L-ribulose 5-phosphate to D-xylulose 5-phosphate. May be involved in the utilization of 2,3- diketo-L-gulonate [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790008, Length=230, Percent_Identity=76.0869565217391, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI1786247, Length=230, Percent_Identity=71.7391304347826, Blast_Score=349, Evalue=9e-98,
Organism=Escherichia coli, GI1790642, Length=230, Percent_Identity=64.3478260869565, Blast_Score=310, Evalue=7e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004661 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =5.1.3.4 [H]

Molecular weight: Translated: 25701; Mature: 25701

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLSQLKQQVLEANLDLPRHNLVTFTWGNVSAVDRERGLVVIKPSGVEYEHMVAEDMVV
CCCHHHHHHHHHHHCCCCCCCCEEEEECCCEEEECCCCCEEEECCCCCCHHHHHHHCEEE
VSLASGQTVEGSKKPSSDTATHLALYREFADIGGIVHTHSRHATIWAQAGLDIPAWGTTH
EEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCCCC
ADYFYGAIPCTRLMTEDEIAQDYELETGKVIIDTFHRRGISPNAIPAVLVNSHGPFAWGK
CCCEECCCCHHHHCCHHHHHHCCCCCCCCEEEEHHHHCCCCCCCCEEEEEECCCCCCCCC
DAHSAVHNAVVLEEIAYMGIFSRQLTPGISSMQPALLDKHYLRKHGKNAYYGQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLTLSQLKQQVLEANLDLPRHNLVTFTWGNVSAVDRERGLVVIKPSGVEYEHMVAEDMVV
CCCHHHHHHHHHHHCCCCCCCCEEEEECCCEEEECCCCCEEEECCCCCCHHHHHHHCEEE
VSLASGQTVEGSKKPSSDTATHLALYREFADIGGIVHTHSRHATIWAQAGLDIPAWGTTH
EEECCCCEECCCCCCCCHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCCCCCCCCCCC
ADYFYGAIPCTRLMTEDEIAQDYELETGKVIIDTFHRRGISPNAIPAVLVNSHGPFAWGK
CCCEECCCCHHHHCCHHHHHHCCCCCCCCEEEEHHHHCCCCCCCCEEEEEECCCCCCCCC
DAHSAVHNAVVLEEIAYMGIFSRQLTPGISSMQPALLDKHYLRKHGKNAYYGQ
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 11741871 [H]