Click here to switch to the map view.

The map label for this gene is ygfA [H]

Identifier: 157372156

GI number: 157372156

Start: 4345624

End: 4346304

Strand: Direct

Name: ygfA [H]

Synonym: Spro_3922

Alternate gene names: 157372156

Gene position: 4345624-4346304 (Clockwise)

Preceding gene: 157372155

Following gene: 157372159

Centisome position: 79.75

GC content: 55.8

Gene sequence:

>681_bases
ATGGGTTCAAGGGTTACAGCCTGCGACGGCATCTCGGAGATTCCCCCTTCCTCAGCGGTAAGTGTGCTGACTATGTCTTT
TCAAGCCCAGTATGCCCAGCAGCGGCAGAACATCCGTAACCAAATCCGTCAGCGTCGACGCGCCCTAACCTCTGAACAAC
AAAATAACTTTGCTCTGCAAACTGCCGAACGTATCGCTACGCATCCGCGCATCCAGGCGGCACACAGCATTGCAGTATTT
TTGTCGTTTGACGGTGAGTTGGATACCCGTCCGCTGATTGAACGGTTATGGCAACAGGCCAAGCAAGTCTATCTGCCGGT
GTTGCACCCGTTTAGCCCCGGCAACCTGCTGTTCCTGCGTTACACCCCGGAAACGCCGCTGGTTAACAACCGTTTCAATA
TCCTTGAGCCACAGCTCGATGTGCGCAACGTCTTGCCGGTCGGATCACTCGACGTGGTGCTGACGCCATTGGTGGCGTTT
GACAGCTCGGGCCAGCGTTTGGGGATGGGCGGCGGTTTTTACGATCGCACTCTGCAAAACTGGCAGCATCTCGGCCCCTA
CCCGATCGGGTTGGCGCATGACTGCCAGCAGGTGGAACAGCTGCCGGTGGAGCATTGGGATATCCCGCTGCCGGAAATCA
TTACCCCATCTCAAAATTGGACATGGCAGATAGCCAAATAG

Upstream 100 bases:

>100_bases
CCGATATTTAGTACCAACAGAATGTGATGATCCGCGATCGGTGTGCATGCTCGGCCCGCCGAGAAGCCTTAAGATTGCGA
CAGCACGTTCACCTTGAACC

Downstream 100 bases:

>100_bases
AAAAGGCCGGAAAAATCCGGCCTTTTTGTCACCGCGTATTCAATCAGAGCAGCAGGCGAGCACGGATAGTGCCGTCAATA
GCCTTCATGCGTTGCAGTGC

Product: 5-formyltetrahydrofolate cyclo-ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MGSRVTACDGISEIPPSSAVSVLTMSFQAQYAQQRQNIRNQIRQRRRALTSEQQNNFALQTAERIATHPRIQAAHSIAVF
LSFDGELDTRPLIERLWQQAKQVYLPVLHPFSPGNLLFLRYTPETPLVNNRFNILEPQLDVRNVLPVGSLDVVLTPLVAF
DSSGQRLGMGGGFYDRTLQNWQHLGPYPIGLAHDCQQVEQLPVEHWDIPLPEIITPSQNWTWQIAK

Sequences:

>Translated_226_residues
MGSRVTACDGISEIPPSSAVSVLTMSFQAQYAQQRQNIRNQIRQRRRALTSEQQNNFALQTAERIATHPRIQAAHSIAVF
LSFDGELDTRPLIERLWQQAKQVYLPVLHPFSPGNLLFLRYTPETPLVNNRFNILEPQLDVRNVLPVGSLDVVLTPLVAF
DSSGQRLGMGGGFYDRTLQNWQHLGPYPIGLAHDCQQVEQLPVEHWDIPLPEIITPSQNWTWQIAK
>Mature_225_residues
GSRVTACDGISEIPPSSAVSVLTMSFQAQYAQQRQNIRNQIRQRRRALTSEQQNNFALQTAERIATHPRIQAAHSIAVFL
SFDGELDTRPLIERLWQQAKQVYLPVLHPFSPGNLLFLRYTPETPLVNNRFNILEPQLDVRNVLPVGSLDVVLTPLVAFD
SSGQRLGMGGGFYDRTLQNWQHLGPYPIGLAHDCQQVEQLPVEHWDIPLPEIITPSQNWTWQIAK

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=195, Percent_Identity=30.2564102564103, Blast_Score=95, Evalue=4e-20,
Organism=Escherichia coli, GI1789278, Length=181, Percent_Identity=68.5082872928177, Blast_Score=266, Evalue=6e-73,
Organism=Caenorhabditis elegans, GI17510857, Length=194, Percent_Identity=26.2886597938144, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 25629; Mature: 25497

Theoretical pI: Translated: 7.14; Mature: 7.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSRVTACDGISEIPPSSAVSVLTMSFQAQYAQQRQNIRNQIRQRRRALTSEQQNNFALQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TAERIATHPRIQAAHSIAVFLSFDGELDTRPLIERLWQQAKQVYLPVLHPFSPGNLLFLR
HHHHHHCCCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
YTPETPLVNNRFNILEPQLDVRNVLPVGSLDVVLTPLVAFDSSGQRLGMGGGFYDRTLQN
ECCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCEECCCCCHHHHHHHH
WQHLGPYPIGLAHDCQQVEQLPVEHWDIPLPEIITPSQNWTWQIAK
HHHCCCCCCCHHHHHHHHHHCCHHHCCCCCCHHCCCCCCCEEEECC
>Mature Secondary Structure 
GSRVTACDGISEIPPSSAVSVLTMSFQAQYAQQRQNIRNQIRQRRRALTSEQQNNFALQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
TAERIATHPRIQAAHSIAVFLSFDGELDTRPLIERLWQQAKQVYLPVLHPFSPGNLLFLR
HHHHHHCCCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
YTPETPLVNNRFNILEPQLDVRNVLPVGSLDVVLTPLVAFDSSGQRLGMGGGFYDRTLQN
ECCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHHHHHHCCCCCCEECCCCCHHHHHHHH
WQHLGPYPIGLAHDCQQVEQLPVEHWDIPLPEIITPSQNWTWQIAK
HHHCCCCCCCHHHHHHHHHHCCHHHCCCCCCHHCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]