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The map label for this gene is cbpA

Identifier: 157372095

GI number: 157372095

Start: 4272508

End: 4273437

Strand: Direct

Name: cbpA

Synonym: Spro_3860

Alternate gene names: 157372095

Gene position: 4272508-4273437 (Clockwise)

Preceding gene: 157372094

Following gene: 157372096

Centisome position: 78.41

GC content: 54.84

Gene sequence:

>930_bases
ATGGAATTCAAGGACTACTATGCCATTTTAGGGGTTAAGCCGGCGGACGATCTCAAGGCAATCAAAACTGCCTATCGCCG
ACTGGCACGAAAATATCACCCCGACGTCAGCACCGAATCGAATGCCGAGGAACAGTTCAAACTGGTCGCCGAAGCCTATG
AAGTGCTGAAAGACGACGAACGCCGCGCCGAATATGATCAACTGCGAGAGCACCGCAACGATCCCAATTTTGGCCGCCAG
ACGCAGCATGGCAGTGCTCATAACGCCGAAGATTTTTCCGATATTTTCTCCTCCATGTTCGGCGAACATGCCCGTGGCCA
ACAACATCGTCAACGACGTCAGGGCATGCGCGGCCAGGATGTTGAAATGGAAGTGGCTATCTTCCTGGAAGAAACCCAGG
CCGAGCAAACCCGTACCATTCGCTATAGCCTGCCGGTATATAACGCTTTCGGCATGGTGGAGCAGGAAATTCCTAAAACC
CTTAATGTGAAAATCCCCGCCGGCGTTGGCGATGGCGAACGCATTCGTCTTAAGGGCCAGGGCGGACCAGGAACTGACGG
TGGTGCCAGCGGCGATCTCTATCTGATCATCCGCATTGCTCCGCATCCATTGTTCGACATCGTCGGTCACAATCTGGAGA
TCGTGCTGCCAGTCGCCCCGTGGGAAGCCGCACTCGGCGCCAAAGTACCGGTACCCACACTGAAAGACAGTATCCTGTTG
ACCATTCCTGCCGGTAGCCAAACCGGGCAGCGCTTGCGCATCAAGGGAAAAGGCCTGGTCGGCAAAAAAGAAACCGGGGA
TTTGTATGCCGTGATCAAGGTCATGATGCCACCGAAGCCGGACGAAAAAAGCGCCGCGCTGTGGCAACAGTTGGCAGAAG
CCCAGCAGAGCTTCGATCCGCGCAAAGACTGGAGTAAGCAAAATGGCTAA

Upstream 100 bases:

>100_bases
TCGGGACATCAACGACAAACAGCCCGACTAAGAGTAAAGTTTCACCCAATACAGGTTCAACTATCCCCCTGACGAAAGAT
TGAAGTGAGATGATAACGCT

Downstream 100 bases:

>100_bases
CGTAACAGTAACTTTCACCATTACCGAGTTTTGCCTGCACACCGGCGTTTCACAGGATGAGCTGACGGAAATTGTCGGGC
TGGGAGTGATTCAACCGCGC

Product: curved DNA-binding protein CbpA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MEFKDYYAILGVKPADDLKAIKTAYRRLARKYHPDVSTESNAEEQFKLVAEAYEVLKDDERRAEYDQLREHRNDPNFGRQ
TQHGSAHNAEDFSDIFSSMFGEHARGQQHRQRRQGMRGQDVEMEVAIFLEETQAEQTRTIRYSLPVYNAFGMVEQEIPKT
LNVKIPAGVGDGERIRLKGQGGPGTDGGASGDLYLIIRIAPHPLFDIVGHNLEIVLPVAPWEAALGAKVPVPTLKDSILL
TIPAGSQTGQRLRIKGKGLVGKKETGDLYAVIKVMMPPKPDEKSAALWQQLAEAQQSFDPRKDWSKQNG

Sequences:

>Translated_309_residues
MEFKDYYAILGVKPADDLKAIKTAYRRLARKYHPDVSTESNAEEQFKLVAEAYEVLKDDERRAEYDQLREHRNDPNFGRQ
TQHGSAHNAEDFSDIFSSMFGEHARGQQHRQRRQGMRGQDVEMEVAIFLEETQAEQTRTIRYSLPVYNAFGMVEQEIPKT
LNVKIPAGVGDGERIRLKGQGGPGTDGGASGDLYLIIRIAPHPLFDIVGHNLEIVLPVAPWEAALGAKVPVPTLKDSILL
TIPAGSQTGQRLRIKGKGLVGKKETGDLYAVIKVMMPPKPDEKSAALWQQLAEAQQSFDPRKDWSKQNG
>Mature_309_residues
MEFKDYYAILGVKPADDLKAIKTAYRRLARKYHPDVSTESNAEEQFKLVAEAYEVLKDDERRAEYDQLREHRNDPNFGRQ
TQHGSAHNAEDFSDIFSSMFGEHARGQQHRQRRQGMRGQDVEMEVAIFLEETQAEQTRTIRYSLPVYNAFGMVEQEIPKT
LNVKIPAGVGDGERIRLKGQGGPGTDGGASGDLYLIIRIAPHPLFDIVGHNLEIVLPVAPWEAALGAKVPVPTLKDSILL
TIPAGSQTGQRLRIKGKGLVGKKETGDLYAVIKVMMPPKPDEKSAALWQQLAEAQQSFDPRKDWSKQNG

Specific function: DNA-binding protein that preferentially recognizes a curved DNA sequence. It is probably a functional analog of DnaJ; displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adapt

COG id: COG2214

COG function: function code O; DnaJ-class molecular chaperone

Gene ontology:

Cell location: Cytoplasm, nucleoid

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 J domain

Homologues:

Organism=Homo sapiens, GI6631085, Length=318, Percent_Identity=31.1320754716981, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI201862518, Length=343, Percent_Identity=27.1137026239067, Blast_Score=95, Evalue=9e-20,
Organism=Homo sapiens, GI56549115, Length=343, Percent_Identity=27.1137026239067, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI201862587, Length=343, Percent_Identity=27.1137026239067, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI7706495, Length=295, Percent_Identity=29.8305084745763, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI39204547, Length=313, Percent_Identity=28.7539936102236, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI5453690, Length=339, Percent_Identity=26.2536873156342, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI194328758, Length=126, Percent_Identity=38.0952380952381, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI194328760, Length=126, Percent_Identity=38.0952380952381, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI205360840, Length=103, Percent_Identity=40.7766990291262, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI205360838, Length=103, Percent_Identity=40.7766990291262, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI4504511, Length=137, Percent_Identity=35.7664233576642, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI9558755, Length=65, Percent_Identity=50.7692307692308, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI194306642, Length=110, Percent_Identity=37.2727272727273, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI194306640, Length=110, Percent_Identity=37.2727272727273, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI23503241, Length=65, Percent_Identity=47.6923076923077, Blast_Score=65, Evalue=8e-11,
Organism=Escherichia coli, GI1787235, Length=308, Percent_Identity=75.3246753246753, Blast_Score=481, Evalue=1e-137,
Organism=Escherichia coli, GI1786197, Length=352, Percent_Identity=34.0909090909091, Blast_Score=169, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17553098, Length=328, Percent_Identity=28.0487804878049, Blast_Score=100, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17553096, Length=328, Percent_Identity=28.0487804878049, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17534355, Length=317, Percent_Identity=27.4447949526814, Blast_Score=88, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI212645553, Length=337, Percent_Identity=27.0029673590504, Blast_Score=77, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6324265, Length=139, Percent_Identity=38.8489208633094, Blast_Score=70, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24658562, Length=339, Percent_Identity=30.6784660766962, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24658555, Length=339, Percent_Identity=30.6784660766962, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI85726398, Length=337, Percent_Identity=28.7833827893175, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI18858081, Length=279, Percent_Identity=27.9569892473118, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19920464, Length=318, Percent_Identity=24.2138364779874, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI45552813, Length=78, Percent_Identity=50, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45549272, Length=78, Percent_Identity=50, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI45552811, Length=78, Percent_Identity=50, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24668492, Length=64, Percent_Identity=50, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CBPA_SERP5 (A8GIL6)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480084.1
- ProteinModelPortal:   A8GIL6
- STRING:   A8GIL6
- GeneID:   5606072
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3860
- eggNOG:   COG2214
- HOGENOM:   HBG635315
- OMA:   IFDVMEN
- ProtClustDB:   PRK10266
- BioCyc:   SPRO399741:SPRO_3860-MONOMER
- GO:   GO:0005737
- GO:   GO:0009295
- HAMAP:   MF_01154
- InterPro:   IPR002939
- InterPro:   IPR001623
- InterPro:   IPR018253
- InterPro:   IPR008971
- InterPro:   IPR015609
- InterPro:   IPR003095
- Gene3D:   G3DSA:1.10.287.110
- PANTHER:   PTHR11821
- PRINTS:   PR00625
- SMART:   SM00271

Pfam domain/function: PF00226 DnaJ; PF01556 DnaJ_C; SSF46565 DnaJ_N; SSF49493 HSP40_DnaJ_pep

EC number: NA

Molecular weight: Translated: 34592; Mature: 34592

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS00636 DNAJ_1; PS50076 DNAJ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFKDYYAILGVKPADDLKAIKTAYRRLARKYHPDVSTESNAEEQFKLVAEAYEVLKDDE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHH
RRAEYDQLREHRNDPNFGRQTQHGSAHNAEDFSDIFSSMFGEHARGQQHRQRRQGMRGQD
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
VEMEVAIFLEETQAEQTRTIRYSLPVYNAFGMVEQEIPKTLNVKIPAGVGDGERIRLKGQ
CEEEEEEEEEHHHCCCCEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEC
GGPGTDGGASGDLYLIIRIAPHPLFDIVGHNLEIVLPVAPWEAALGAKVPVPTLKDSILL
CCCCCCCCCCCCEEEEEEECCCCHHHHHCCCEEEEEEECCHHHHCCCCCCCCCCCCCEEE
TIPAGSQTGQRLRIKGKGLVGKKETGDLYAVIKVMMPPKPDEKSAALWQQLAEAQQSFDP
EECCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
RKDWSKQNG
CCCCCCCCC
>Mature Secondary Structure
MEFKDYYAILGVKPADDLKAIKTAYRRLARKYHPDVSTESNAEEQFKLVAEAYEVLKDDE
CCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCHH
RRAEYDQLREHRNDPNFGRQTQHGSAHNAEDFSDIFSSMFGEHARGQQHRQRRQGMRGQD
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCC
VEMEVAIFLEETQAEQTRTIRYSLPVYNAFGMVEQEIPKTLNVKIPAGVGDGERIRLKGQ
CEEEEEEEEEHHHCCCCEEEEEECCHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEEC
GGPGTDGGASGDLYLIIRIAPHPLFDIVGHNLEIVLPVAPWEAALGAKVPVPTLKDSILL
CCCCCCCCCCCCEEEEEEECCCCHHHHHCCCEEEEEEECCHHHHCCCCCCCCCCCCCEEE
TIPAGSQTGQRLRIKGKGLVGKKETGDLYAVIKVMMPPKPDEKSAALWQQLAEAQQSFDP
EECCCCCCCCEEEEECCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
RKDWSKQNG
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA