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The map label for this gene is xni

Identifier: 157372037

GI number: 157372037

Start: 4202785

End: 4203540

Strand: Direct

Name: xni

Synonym: Spro_3802

Alternate gene names: 157372037

Gene position: 4202785-4203540 (Clockwise)

Preceding gene: 157372036

Following gene: 157372042

Centisome position: 77.13

GC content: 56.61

Gene sequence:

>756_bases
ATGATGATACACCTACTGATTGTCGATGCCCTCAACCTGATCCGCCGCATACACGCCGTGCAGGGGTCCCCCTGTGTGAA
TGCCTGCCAGCACGCACTGCAACAGTTGATTCAGCACAGTCGGCCAACGCACGCCGTAGCGGTGTTCGATGAGGATGACC
GCAGCGAAAGCTGGCGCCACCAAATCCTGCCCGACTACAAGGCCGGACGTTCGCCCATGCCGGACAATTTGCAGCAGGAA
ATGCCGCAGTTACGGCAAGCATTTGAATCGCTTGGTGTTGCCTGTTGGCACTCTCCAGGCAATGAGGCCGACGATCTGGC
GGCAACGCTGACCGCCAAGGTTGCAGGCGGCGGCCATCAGGTGACCATTGTGTCCACCGACAAAGGCTATTGCCAACTAT
TGGCACCCAGCGTGCAGATCCGCGATTATTTCCAAAAACGTTGGCTGGATATGCCGTTTGTGCAGCAAGAGTTCGGCGTA
TCGCCACAACAATTGTCGGATTACTGGGGGCTGGCGGGAATAAGCAGCAGCAAAATCCCCGGCGTGGCGGGGATTGGGCC
GAAGACGGCGGTATTGCTGTTACAGCAGGCAGGTTCACTGGATGGGTTATATCAGGATTTGGAACAAGTGCCAGAAAAAT
GGCGCGGCAAGCTAGAACAGCACCGCGAGATGGCCTACGTCAGCAAAAGAGTCGCTACCTTGCGAACCGATCTGGCATTA
ACCGGCAACCTGCAGCAACTGCGGTTACCGGTTTAA

Upstream 100 bases:

>100_bases
TGCCAGGCACCGCTTATGTGCCCTGTTACGAAATAGTCGCTTAATGAGCAATCCGGGGCGGCCTGACAGCCGCCCTTCTT
TTTTCTGACCTTGTAAGCCC

Downstream 100 bases:

>100_bases
TCACTGGCGCTGAAGACAGCGCCCTGTCATTTAATCGCGCTCGTCGCGGCGGCCTGCCACGGCCGACCACATACGACGGA
CGTGCACGGTGACTTCTTCA

Product: exonuclease IX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MMIHLLIVDALNLIRRIHAVQGSPCVNACQHALQQLIQHSRPTHAVAVFDEDDRSESWRHQILPDYKAGRSPMPDNLQQE
MPQLRQAFESLGVACWHSPGNEADDLAATLTAKVAGGGHQVTIVSTDKGYCQLLAPSVQIRDYFQKRWLDMPFVQQEFGV
SPQQLSDYWGLAGISSSKIPGVAGIGPKTAVLLLQQAGSLDGLYQDLEQVPEKWRGKLEQHREMAYVSKRVATLRTDLAL
TGNLQQLRLPV

Sequences:

>Translated_251_residues
MMIHLLIVDALNLIRRIHAVQGSPCVNACQHALQQLIQHSRPTHAVAVFDEDDRSESWRHQILPDYKAGRSPMPDNLQQE
MPQLRQAFESLGVACWHSPGNEADDLAATLTAKVAGGGHQVTIVSTDKGYCQLLAPSVQIRDYFQKRWLDMPFVQQEFGV
SPQQLSDYWGLAGISSSKIPGVAGIGPKTAVLLLQQAGSLDGLYQDLEQVPEKWRGKLEQHREMAYVSKRVATLRTDLAL
TGNLQQLRLPV
>Mature_251_residues
MMIHLLIVDALNLIRRIHAVQGSPCVNACQHALQQLIQHSRPTHAVAVFDEDDRSESWRHQILPDYKAGRSPMPDNLQQE
MPQLRQAFESLGVACWHSPGNEADDLAATLTAKVAGGGHQVTIVSTDKGYCQLLAPSVQIRDYFQKRWLDMPFVQQEFGV
SPQQLSDYWGLAGISSSKIPGVAGIGPKTAVLLLQQAGSLDGLYQDLEQVPEKWRGKLEQHREMAYVSKRVATLRTDLAL
TGNLQQLRLPV

Specific function: May have a role in processing of nucleic acids. It is probably not an exonuclease; metal-binding residues found in paralogs are missing

COG id: COG0258

COG function: function code L; 5'-3' exonuclease (including N-terminal domain of PolI)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 5'-3' exonuclease domain

Homologues:

Organism=Escherichia coli, GI226510970, Length=249, Percent_Identity=71.4859437751004, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1790294, Length=261, Percent_Identity=34.4827586206897, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XNI_SERP5 (A8GIF8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480026.1
- ProteinModelPortal:   A8GIF8
- SMR:   A8GIF8
- STRING:   A8GIF8
- GeneID:   5606967
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3802
- eggNOG:   COG0258
- HOGENOM:   HBG701384
- OMA:   HGEKVTI
- ProtClustDB:   PRK09482
- BioCyc:   SPRO399741:SPRO_3802-MONOMER
- HAMAP:   MF_01192
- InterPro:   IPR020046
- InterPro:   IPR020045
- InterPro:   IPR002421
- InterPro:   IPR020047
- InterPro:   IPR008918
- InterPro:   IPR022895
- SMART:   SM00475
- SMART:   SM00279

Pfam domain/function: PF01367 5_3_exonuc; PF02739 5_3_exonuc_N; SSF47807 5_3_exo_C

EC number: 3.1.11.- [C]

Molecular weight: Translated: 27907; Mature: 27907

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIHLLIVDALNLIRRIHAVQGSPCVNACQHALQQLIQHSRPTHAVAVFDEDDRSESWRH
CEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
QILPDYKAGRSPMPDNLQQEMPQLRQAFESLGVACWHSPGNEADDLAATLTAKVAGGGHQ
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCCCCCEE
VTIVSTDKGYCQLLAPSVQIRDYFQKRWLDMPFVQQEFGVSPQQLSDYWGLAGISSSKIP
EEEEECCCCEEEHHCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCC
GVAGIGPKTAVLLLQQAGSLDGLYQDLEQVPEKWRGKLEQHREMAYVSKRVATLRTDLAL
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGNLQQLRLPV
CCCHHHHCCCC
>Mature Secondary Structure
MMIHLLIVDALNLIRRIHAVQGSPCVNACQHALQQLIQHSRPTHAVAVFDEDDRSESWRH
CEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHH
QILPDYKAGRSPMPDNLQQEMPQLRQAFESLGVACWHSPGNEADDLAATLTAKVAGGGHQ
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHCCCCCEE
VTIVSTDKGYCQLLAPSVQIRDYFQKRWLDMPFVQQEFGVSPQQLSDYWGLAGISSSKIP
EEEEECCCCEEEHHCCHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHHCCCCCCCCCCC
GVAGIGPKTAVLLLQQAGSLDGLYQDLEQVPEKWRGKLEQHREMAYVSKRVATLRTDLAL
CCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TGNLQQLRLPV
CCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA