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The map label for this gene is srlE [H]

Identifier: 157371805

GI number: 157371805

Start: 3947798

End: 3948778

Strand: Direct

Name: srlE [H]

Synonym: Spro_3570

Alternate gene names: 157371805

Gene position: 3947798-3948778 (Clockwise)

Preceding gene: 157371804

Following gene: 157371806

Centisome position: 72.45

GC content: 60.65

Gene sequence:

>981_bases
ATGAGTGCTTTTATCCGTATTGAGAAAGGCGATAGCGGCTGGGGTGGCCCGTTGCAGTTACCGATCGAGCCGGGGAAAAA
AGTGGTGTACATCACTGCCGGTACTCGCCCGTCGATCGTCGACCGGCTTAGCGAACTGACCGGCTGGCCGGCCGTCGATG
GCTTTAAGGAAGGCGAACCACCGGCGGAAGAGATTGGCGTGATGGTCATTGACTGTGGCGGCACCCTGCGCTGCGGTCTG
TACCCCAAACGCCGTATTCCGACGGTCAATATCCACGCTACCGGTCAATCCGGCCCGCTGGCGAAATTTATCCTCGAGGA
TATTTACGTCTCCGGGGTACGCGACAGCAACATCAGCCGGGTTGAATCGGCAACAGAGACGGCGCAAGCGGCCCCCGCCC
CGCAACCCAAGGGACGGGATTATGACACCAGCAAAAAAATCACTGAGCAGAGCGACGGCCTGTTGGCGAAAGTCGGCATG
GGCATGGGTTCGGTGGTGGCGGTGTTCTTCCAGTCTGGCCGCGACACCATCGACACGGTACTGAAAACCATTCTGCCGTT
TATGGCGTTCGTCTCGGCGCTGATCGGCATCATCATGGCCTCCGGCCTGGGGGATTTTATTGCCCACGGCCTGACGCCAT
TGGCCAGCAGCCCGATTGGCCTGGTAACGCTGGCGCTGATTTGTTCCTTCCCGCTGCTGTCGCCGTTCCTCGGCCCTGGC
GCGGTGATCGCTCAGGTGATCGGCGTATTGGTCGGGGTTCAGATTGGCCTGGGTCATATTCCACCCCAGTTGGCGCTGCC
CGCGCTATTTGCAATTAACGCGCAGGCCGCCTGCGACTTTATCCCGGTCGGTCTGTCTCTGGCGGAAGCCAAACAGGACA
CGGTGCGGGTCGGCGTGCCTTCGGTTCTGGTCGGACGTTTCCTGACCGGCGCACCTACGGTGCTGATCGCCTGGGCCGCC
TCGGCCTTCATCTACCAATAA

Upstream 100 bases:

>100_bases
TTTCCGCGGTTGGGTAACCGATCTCACCACCAGCCTGTTCGAACGCAAGATGGGCATCCGCCTGGACCGTCAGGTACAAC
TTTAATCCGTGGAGTTCAGC

Downstream 100 bases:

>100_bases
CTTTTACTGCCAGGGGCTAGCTATGAACACCATTTTCCAAACCACCATCACCCAGATTGGCGACAGTGCTCGCGAGGCGC
TGCTGGACGACATGCTGATC

Product: PTS system glucitol/sorbitol-specific transporter subunit IIBC

Products: NA

Alternate protein names: EII-Gut; PTS system glucitol/sorbitol-specific EIIB component [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSAFIRIEKGDSGWGGPLQLPIEPGKKVVYITAGTRPSIVDRLSELTGWPAVDGFKEGEPPAEEIGVMVIDCGGTLRCGL
YPKRRIPTVNIHATGQSGPLAKFILEDIYVSGVRDSNISRVESATETAQAAPAPQPKGRDYDTSKKITEQSDGLLAKVGM
GMGSVVAVFFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDFIAHGLTPLASSPIGLVTLALICSFPLLSPFLGPG
AVIAQVIGVLVGVQIGLGHIPPQLALPALFAINAQAACDFIPVGLSLAEAKQDTVRVGVPSVLVGRFLTGAPTVLIAWAA
SAFIYQ

Sequences:

>Translated_326_residues
MSAFIRIEKGDSGWGGPLQLPIEPGKKVVYITAGTRPSIVDRLSELTGWPAVDGFKEGEPPAEEIGVMVIDCGGTLRCGL
YPKRRIPTVNIHATGQSGPLAKFILEDIYVSGVRDSNISRVESATETAQAAPAPQPKGRDYDTSKKITEQSDGLLAKVGM
GMGSVVAVFFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDFIAHGLTPLASSPIGLVTLALICSFPLLSPFLGPG
AVIAQVIGVLVGVQIGLGHIPPQLALPALFAINAQAACDFIPVGLSLAEAKQDTVRVGVPSVLVGRFLTGAPTVLIAWAA
SAFIYQ
>Mature_325_residues
SAFIRIEKGDSGWGGPLQLPIEPGKKVVYITAGTRPSIVDRLSELTGWPAVDGFKEGEPPAEEIGVMVIDCGGTLRCGLY
PKRRIPTVNIHATGQSGPLAKFILEDIYVSGVRDSNISRVESATETAQAAPAPQPKGRDYDTSKKITEQSDGLLAKVGMG
MGSVVAVFFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDFIAHGLTPLASSPIGLVTLALICSFPLLSPFLGPGA
VIAQVIGVLVGVQIGLGHIPPQLALPALFAINAQAACDFIPVGLSLAEAKQDTVRVGVPSVLVGRFLTGAPTVLIAWAAS
AFIYQ

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG3732

COG function: function code G; Phosphotransferase system sorbitol-specific component IIBC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994905, Length=322, Percent_Identity=82.6086956521739, Blast_Score=533, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011638
- InterPro:   IPR011618
- InterPro:   IPR004702 [H]

Pfam domain/function: PF07663 EIIBC-GUT_C; PF03612 EIIBC-GUT_N [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 33986; Mature: 33855

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS51102 PTS_EIIB_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFIRIEKGDSGWGGPLQLPIEPGKKVVYITAGTRPSIVDRLSELTGWPAVDGFKEGEP
CCCEEEEECCCCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCC
PAEEIGVMVIDCGGTLRCGLYPKRRIPTVNIHATGQSGPLAKFILEDIYVSGVRDSNISR
CHHHCCEEEEECCCEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHH
VESATETAQAAPAPQPKGRDYDTSKKITEQSDGLLAKVGMGMGSVVAVFFQSGRDTIDTV
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHHHHH
LKTILPFMAFVSALIGIIMASGLGDFIAHGLTPLASSPIGLVTLALICSFPLLSPFLGPG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCH
AVIAQVIGVLVGVQIGLGHIPPQLALPALFAINAQAACDFIPVGLSLAEAKQDTVRVGVP
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHCCEEECCCHHHHHCCCCEECCCH
SVLVGRFLTGAPTVLIAWAASAFIYQ
HHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAFIRIEKGDSGWGGPLQLPIEPGKKVVYITAGTRPSIVDRLSELTGWPAVDGFKEGEP
CCEEEEECCCCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCC
PAEEIGVMVIDCGGTLRCGLYPKRRIPTVNIHATGQSGPLAKFILEDIYVSGVRDSNISR
CHHHCCEEEEECCCEEEECCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCHHH
VESATETAQAAPAPQPKGRDYDTSKKITEQSDGLLAKVGMGMGSVVAVFFQSGRDTIDTV
HHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCEEEECCCCHHHHHHHHHHCCCHHHHHH
LKTILPFMAFVSALIGIIMASGLGDFIAHGLTPLASSPIGLVTLALICSFPLLSPFLGPG
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCH
AVIAQVIGVLVGVQIGLGHIPPQLALPALFAINAQAACDFIPVGLSLAEAKQDTVRVGVP
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHCCEEECCCHHHHHCCCCEECCCH
SVLVGRFLTGAPTVLIAWAASAFIYQ
HHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3553176; 9205837; 9278503 [H]