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The map label for this gene is yeiR [H]

Identifier: 157371478

GI number: 157371478

Start: 3574691

End: 3575665

Strand: Direct

Name: yeiR [H]

Synonym: Spro_3241

Alternate gene names: 157371478

Gene position: 3574691-3575665 (Clockwise)

Preceding gene: 157371476

Following gene: 157371479

Centisome position: 65.6

GC content: 56.41

Gene sequence:

>975_bases
ATGACCAAAACTAACCTGATCACCGGTTTTCTCGGCAGCGGTAAAACCACCACCATTCGTCACTTGCTGGCTAACAAACC
GGAACATGAGCGTTGGGCAGTGCTGGTAAACGAGTTTGGTGAAATTGGTATTGATGGCGCATTGCTGGCAGACAGCGGTG
CGGTGTTAAAGGAGATCCCTGGCGGTTGTATGTGTTGTGTGAACGGCTTGCCGATGCAGGTCGGGCTGAATATGCTGCTG
CAACAGAGTAAACCCGACCGTCTGTTGATCGAACCTACCGGCCTGGGCCACCCGAAACAGATCCTGTCATTGCTGATGCA
GGACAGCTACGCCGGCTGGATCGATCTACAGGCCACCCTGTGCCTGTTGGACGCACGTCAGCTCAGCGAACCGCGCTATG
TAGAAAACGAAAACTTCCGCGATCAACTGGCGGCGGCCGACGTTATTCTGGCCAGCAAAAGCGACACCTATCAGCCGCAG
GATCTGCTGGCCCTGCAGCAATGGGCGCAGCAGGACTCCCTGCAGCGGCCGCTTTATCACATTCAACAGGGCCGGGCGGA
TGTCACCTTGCTGGACCTGCCTCGCACGAATCGCACAGAATTACCGAATGCCCAGCATCATCATAGCCACAGCAAAACAC
AGGGCTTGGCCGCATTGCGGCTGCCGGAAACTTCGCGCTGGCGGCGAGCGCTCAATCAGGGCCAGGGATTTACCAGCTGT
GGCTGGATCTTTGACGCCGACACGGTATTCGATACCGTTGGCATCATGGAGTGGATACGGCTGGCACCGGTCGAACGCGC
CAAAGGCGTAGTGCGCATTGCTGAAGGCACTCTGTTGATCAACCGTCAGGGGCAGGATCTCAATATCGAAACGCGTCCTG
TCGCGCCGCTGGACAGCCGAATTGAACTGATTCACAGCGGGAACGCGGATTGGAACGCGCTGCAATCCAAGCTGTTTAAC
ATTCGTTTAAGTTGA

Upstream 100 bases:

>100_bases
AATTTGTGACCTGACGCAGGTTGAGCAACCTCAAGTGCTAAGGCAAAGCAGGGTTGCTTATTTATTGACCAATAGACATT
ATTAACATCAGGAATAATTT

Downstream 100 bases:

>100_bases
GAACTTTACCGTTAGCCTCTTTTTATTTTTAGACTTAAAACAGGTTATGCCATGACTCGCCGCAATTTACCCTTCATCAT
TTTCTTCAATTTATTGGGCA

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 323

Protein sequence:

>324_residues
MTKTNLITGFLGSGKTTTIRHLLANKPEHERWAVLVNEFGEIGIDGALLADSGAVLKEIPGGCMCCVNGLPMQVGLNMLL
QQSKPDRLLIEPTGLGHPKQILSLLMQDSYAGWIDLQATLCLLDARQLSEPRYVENENFRDQLAAADVILASKSDTYQPQ
DLLALQQWAQQDSLQRPLYHIQQGRADVTLLDLPRTNRTELPNAQHHHSHSKTQGLAALRLPETSRWRRALNQGQGFTSC
GWIFDADTVFDTVGIMEWIRLAPVERAKGVVRIAEGTLLINRQGQDLNIETRPVAPLDSRIELIHSGNADWNALQSKLFN
IRLS

Sequences:

>Translated_324_residues
MTKTNLITGFLGSGKTTTIRHLLANKPEHERWAVLVNEFGEIGIDGALLADSGAVLKEIPGGCMCCVNGLPMQVGLNMLL
QQSKPDRLLIEPTGLGHPKQILSLLMQDSYAGWIDLQATLCLLDARQLSEPRYVENENFRDQLAAADVILASKSDTYQPQ
DLLALQQWAQQDSLQRPLYHIQQGRADVTLLDLPRTNRTELPNAQHHHSHSKTQGLAALRLPETSRWRRALNQGQGFTSC
GWIFDADTVFDTVGIMEWIRLAPVERAKGVVRIAEGTLLINRQGQDLNIETRPVAPLDSRIELIHSGNADWNALQSKLFN
IRLS
>Mature_323_residues
TKTNLITGFLGSGKTTTIRHLLANKPEHERWAVLVNEFGEIGIDGALLADSGAVLKEIPGGCMCCVNGLPMQVGLNMLLQ
QSKPDRLLIEPTGLGHPKQILSLLMQDSYAGWIDLQATLCLLDARQLSEPRYVENENFRDQLAAADVILASKSDTYQPQD
LLALQQWAQQDSLQRPLYHIQQGRADVTLLDLPRTNRTELPNAQHHHSHSKTQGLAALRLPETSRWRRALNQGQGFTSCG
WIFDADTVFDTVGIMEWIRLAPVERAKGVVRIAEGTLLINRQGQDLNIETRPVAPLDSRIELIHSGNADWNALQSKLFNI
RLS

Specific function: Unknown

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI223941779, Length=239, Percent_Identity=30.9623430962343, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI126722884, Length=202, Percent_Identity=31.6831683168317, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI33469141, Length=202, Percent_Identity=31.6831683168317, Blast_Score=79, Evalue=7e-15,
Organism=Homo sapiens, GI148727351, Length=202, Percent_Identity=31.1881188118812, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI146231952, Length=202, Percent_Identity=31.1881188118812, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI223941776, Length=196, Percent_Identity=30.6122448979592, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788499, Length=325, Percent_Identity=69.8461538461538, Blast_Score=459, Evalue=1e-130,
Organism=Escherichia coli, GI87082430, Length=194, Percent_Identity=30.9278350515464, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 36075; Mature: 35944

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKTNLITGFLGSGKTTTIRHLLANKPEHERWAVLVNEFGEIGIDGALLADSGAVLKEIP
CCCCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHCC
GGCMCCVNGLPMQVGLNMLLQQSKPDRLLIEPTGLGHPKQILSLLMQDSYAGWIDLQATL
CCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEHHHHH
CLLDARQLSEPRYVENENFRDQLAAADVILASKSDTYQPQDLLALQQWAQQDSLQRPLYH
HHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IQQGRADVTLLDLPRTNRTELPNAQHHHSHSKTQGLAALRLPETSRWRRALNQGQGFTSC
HHCCCCCEEEEECCCCCCCCCCCCHHHCCCHHHCCEEEEECCCHHHHHHHHHHCCCCCCC
GWIFDADTVFDTVGIMEWIRLAPVERAKGVVRIAEGTLLINRQGQDLNIETRPVAPLDSR
CEEEECHHHHHHHHHHHHHHHCCHHHHCCEEEEECCEEEEECCCCCCCCCCCCCCCCCHH
IELIHSGNADWNALQSKLFNIRLS
HHEEECCCCCHHHHHHHHEEEECC
>Mature Secondary Structure 
TKTNLITGFLGSGKTTTIRHLLANKPEHERWAVLVNEFGEIGIDGALLADSGAVLKEIP
CCCCEEEEECCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEECCCHHHHHCC
GGCMCCVNGLPMQVGLNMLLQQSKPDRLLIEPTGLGHPKQILSLLMQDSYAGWIDLQATL
CCEEEECCCCCHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHCCCCCEEEHHHHH
CLLDARQLSEPRYVENENFRDQLAAADVILASKSDTYQPQDLLALQQWAQQDSLQRPLYH
HHHHHHHCCCCCCCCCCCHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHH
IQQGRADVTLLDLPRTNRTELPNAQHHHSHSKTQGLAALRLPETSRWRRALNQGQGFTSC
HHCCCCCEEEEECCCCCCCCCCCCHHHCCCHHHCCEEEEECCCHHHHHHHHHHCCCCCCC
GWIFDADTVFDTVGIMEWIRLAPVERAKGVVRIAEGTLLINRQGQDLNIETRPVAPLDSR
CEEEECHHHHHHHHHHHHHHHCCHHHHCCEEEEECCEEEEECCCCCCCCCCCCCCCCCHH
IELIHSGNADWNALQSKLFNIRLS
HHEEECCCCCHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]