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The map label for this gene is cph2 [H]

Identifier: 157371308

GI number: 157371308

Start: 3376718

End: 3378268

Strand: Direct

Name: cph2 [H]

Synonym: Spro_3068

Alternate gene names: 157371308

Gene position: 3376718-3378268 (Clockwise)

Preceding gene: 157371307

Following gene: 157371309

Centisome position: 61.97

GC content: 54.22

Gene sequence:

>1551_bases
ATGACACAGCAGCAACTGCAGGATGCCGAACGGCCTCGCAACGGTAAAAACTCCCCGTTATTATTTCAGGCCGGCGTGTT
TGTCGTCATCGTTGCCGTTACGCTGATCCTGTTTAACGCCTGGCAAATTTGGAATGCCCATCAGCGCGACTTGCAAAGTG
CCGAGAATGAATCCGCCAATTTGGCCCGTGCGCTGGCGCAGCATGCCGATGACACCTTTATGCAGACCGACAGTACGCTG
TCCGACCTGAGTGAACGCATTCAGGTTGACGGGCTGGCTCGCCCACAGCTGTTACGATTGCAAAAAGTGATGCAAACACA
GGTGGGTAACCTGCCACAACTGCACGGGCTGTTTGTTTACGATGCGCAAGGTAATTGGGTCGTCACTTCATCAGGCCGCT
TTGTACAAAACGCCAACAATGCCGACCGGGAATATTTTAAATACCACCTCGAGCACAACAGCAATGCAGTTTATATCGGC
AAGGTGGTGCGCAGCCGCTCTACCGGCGATTTGATCATTCCGGTATCACGCCGTTTCAACCACCCGGACGGCAGCTTTGC
CGGGGTCGTGCTGGCCACATTGTATATCAATTATTTCCGCCAGTTTTACGATACCTTTGCACTAAACAGCGATGCTTCAC
TCAATCTGCTATTGGCGGACGGCACCATTCTCTACCGTCGCCCTTATTCCCTGGCGGCCATCGGCAAGAATATTTCCGAG
GGCGTGTTGTTCCGGGAAATATTGCCACATTCCGAATTCGGCAATGCCACCATTACCTCGCGCTACGACAAGGTAGAACG
GATTTACGGCTATTCACGGGTTACCCGCTATCCACTGGTGATTGCCGCCGGGTTGTCGAAAAAAGACGTGCTGGCTGATT
GGCGCAACGATTCCGGCCTGTTTGCCCTGGGTGGTGCCACCCTGCTGGCGATCCTGTTGGCGATGGGGATGGTGTTGATG
CGTCAGATAAACCACAGCGTACGCACCGAAGCCGAACTGATGCGCACTCGCGATCAGCTCACCAGTATCAACCGCACCCT
GGAAGAACTGGCCTTGCTGGACGGCCTGACCGGGCTGGCCAACCGCCGTCAGTTTGATATCGCCTTAAAGAATGAGCTGA
TGCGCGCCTCACGCAACTACCGCAGCGTGGCGCTGTTGATGTTGGATATTGACTATTTCAAGCAGTATAACGACATCTAT
GGCCACGTTGCCGGCGACCAGTGTCTGCAACAGATCGGACAAATGCTCAAGGGAATGGCCAGCCGCAGCAACGACATTAT
GGCCCGCTACGGCGGCGAAGAAATGGCCATCATCTTGCCGGATACCGACGCCCAGGGTGCACTGATTTTCGCCGAGCGCG
TCATTGAAGCGGTGCGGGAGCTAAAAATACCTCATGATGGCAACCCACATGGCGTCATCACCATCAGCATAGGGATCTAC
GCCAAGGTGCCGCATATGTATAACGACACGCCGATGAGCTTTATCAATCAGGCGGACAGCGCACTGTACCAAGCGAAAGC
CCAGGGAAAAAACCGTATTTACTCCGCTTAA

Upstream 100 bases:

>100_bases
TGCCTTATACCCCCGCCCTGAAGGACGGGGTTTTACGGCACACTGGATAAGATGTAGGATTGTTCTTACCTCGATTTAAA
GATTGTACAGCAAGGGTGAC

Downstream 100 bases:

>100_bases
CCCGGTAGGCCGCCTTTAGCAAAAAGGCGGCCTCAGATAAAAAACCCAGGCCACCTAATAGAATTATCATGCCTAATTGA
TGCTTTTGATTAATTTCCAA

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MTQQQLQDAERPRNGKNSPLLFQAGVFVVIVAVTLILFNAWQIWNAHQRDLQSAENESANLARALAQHADDTFMQTDSTL
SDLSERIQVDGLARPQLLRLQKVMQTQVGNLPQLHGLFVYDAQGNWVVTSSGRFVQNANNADREYFKYHLEHNSNAVYIG
KVVRSRSTGDLIIPVSRRFNHPDGSFAGVVLATLYINYFRQFYDTFALNSDASLNLLLADGTILYRRPYSLAAIGKNISE
GVLFREILPHSEFGNATITSRYDKVERIYGYSRVTRYPLVIAAGLSKKDVLADWRNDSGLFALGGATLLAILLAMGMVLM
RQINHSVRTEAELMRTRDQLTSINRTLEELALLDGLTGLANRRQFDIALKNELMRASRNYRSVALLMLDIDYFKQYNDIY
GHVAGDQCLQQIGQMLKGMASRSNDIMARYGGEEMAIILPDTDAQGALIFAERVIEAVRELKIPHDGNPHGVITISIGIY
AKVPHMYNDTPMSFINQADSALYQAKAQGKNRIYSA

Sequences:

>Translated_516_residues
MTQQQLQDAERPRNGKNSPLLFQAGVFVVIVAVTLILFNAWQIWNAHQRDLQSAENESANLARALAQHADDTFMQTDSTL
SDLSERIQVDGLARPQLLRLQKVMQTQVGNLPQLHGLFVYDAQGNWVVTSSGRFVQNANNADREYFKYHLEHNSNAVYIG
KVVRSRSTGDLIIPVSRRFNHPDGSFAGVVLATLYINYFRQFYDTFALNSDASLNLLLADGTILYRRPYSLAAIGKNISE
GVLFREILPHSEFGNATITSRYDKVERIYGYSRVTRYPLVIAAGLSKKDVLADWRNDSGLFALGGATLLAILLAMGMVLM
RQINHSVRTEAELMRTRDQLTSINRTLEELALLDGLTGLANRRQFDIALKNELMRASRNYRSVALLMLDIDYFKQYNDIY
GHVAGDQCLQQIGQMLKGMASRSNDIMARYGGEEMAIILPDTDAQGALIFAERVIEAVRELKIPHDGNPHGVITISIGIY
AKVPHMYNDTPMSFINQADSALYQAKAQGKNRIYSA
>Mature_515_residues
TQQQLQDAERPRNGKNSPLLFQAGVFVVIVAVTLILFNAWQIWNAHQRDLQSAENESANLARALAQHADDTFMQTDSTLS
DLSERIQVDGLARPQLLRLQKVMQTQVGNLPQLHGLFVYDAQGNWVVTSSGRFVQNANNADREYFKYHLEHNSNAVYIGK
VVRSRSTGDLIIPVSRRFNHPDGSFAGVVLATLYINYFRQFYDTFALNSDASLNLLLADGTILYRRPYSLAAIGKNISEG
VLFREILPHSEFGNATITSRYDKVERIYGYSRVTRYPLVIAAGLSKKDVLADWRNDSGLFALGGATLLAILLAMGMVLMR
QINHSVRTEAELMRTRDQLTSINRTLEELALLDGLTGLANRRQFDIALKNELMRASRNYRSVALLMLDIDYFKQYNDIYG
HVAGDQCLQQIGQMLKGMASRSNDIMARYGGEEMAIILPDTDAQGALIFAERVIEAVRELKIPHDGNPHGVITISIGIYA
KVPHMYNDTPMSFINQADSALYQAKAQGKNRIYSA

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Integral Membrane Protein [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=34.8314606741573, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=36.2068965517241, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI145693134, Length=200, Percent_Identity=33, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1787262, Length=173, Percent_Identity=36.4161849710983, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1788381, Length=160, Percent_Identity=35.625, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1787816, Length=162, Percent_Identity=33.9506172839506, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI1787802, Length=183, Percent_Identity=30.0546448087432, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788956, Length=178, Percent_Identity=33.1460674157303, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787541, Length=238, Percent_Identity=28.9915966386555, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081974, Length=158, Percent_Identity=34.8101265822785, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87082007, Length=277, Percent_Identity=24.187725631769, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788085, Length=169, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 57861; Mature: 57730

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQQQLQDAERPRNGKNSPLLFQAGVFVVIVAVTLILFNAWQIWNAHQRDLQSAENESAN
CCHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHH
LARALAQHADDTFMQTDSTLSDLSERIQVDGLARPQLLRLQKVMQTQVGNLPQLHGLFVY
HHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEE
DAQGNWVVTSSGRFVQNANNADREYFKYHLEHNSNAVYIGKVVRSRSTGDLIIPVSRRFN
ECCCCEEEECCCCEEECCCCCCHHHHHHHEECCCCEEEEEHHHHCCCCCCEEEECHHCCC
HPDGSFAGVVLATLYINYFRQFYDTFALNSDASLNLLLADGTILYRRPYSLAAIGKNISE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCHHHHHCCCHHH
GVLFREILPHSEFGNATITSRYDKVERIYGYSRVTRYPLVIAAGLSKKDVLADWRNDSGL
HHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCCCE
FALGGATLLAILLAMGMVLMRQINHSVRTEAELMRTRDQLTSINRTLEELALLDGLTGLA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NRRQFDIALKNELMRASRNYRSVALLMLDIDYFKQYNDIYGHVAGDQCLQQIGQMLKGMA
CCCEEHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SRSNDIMARYGGEEMAIILPDTDAQGALIFAERVIEAVRELKIPHDGNPHGVITISIGIY
CCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEE
AKVPHMYNDTPMSFINQADSALYQAKAQGKNRIYSA
EECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TQQQLQDAERPRNGKNSPLLFQAGVFVVIVAVTLILFNAWQIWNAHQRDLQSAENESAN
CHHHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHH
LARALAQHADDTFMQTDSTLSDLSERIQVDGLARPQLLRLQKVMQTQVGNLPQLHGLFVY
HHHHHHHHCCCHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEE
DAQGNWVVTSSGRFVQNANNADREYFKYHLEHNSNAVYIGKVVRSRSTGDLIIPVSRRFN
ECCCCEEEECCCCEEECCCCCCHHHHHHHEECCCCEEEEEHHHHCCCCCCEEEECHHCCC
HPDGSFAGVVLATLYINYFRQFYDTFALNSDASLNLLLADGTILYRRPYSLAAIGKNISE
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCHHHHHCCCHHH
GVLFREILPHSEFGNATITSRYDKVERIYGYSRVTRYPLVIAAGLSKKDVLADWRNDSGL
HHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCCCE
FALGGATLLAILLAMGMVLMRQINHSVRTEAELMRTRDQLTSINRTLEELALLDGLTGLA
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
NRRQFDIALKNELMRASRNYRSVALLMLDIDYFKQYNDIYGHVAGDQCLQQIGQMLKGMA
CCCEEHHHHHHHHHHHHCCCCEEEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
SRSNDIMARYGGEEMAIILPDTDAQGALIFAERVIEAVRELKIPHDGNPHGVITISIGIY
CCCCCEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEEE
AKVPHMYNDTPMSFINQADSALYQAKAQGKNRIYSA
EECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]