Click here to switch to the map view.

The map label for this gene is pcaI [H]

Identifier: 157371277

GI number: 157371277

Start: 3346435

End: 3347121

Strand: Direct

Name: pcaI [H]

Synonym: Spro_3037

Alternate gene names: 157371277

Gene position: 3346435-3347121 (Clockwise)

Preceding gene: 157371275

Following gene: 157371278

Centisome position: 61.42

GC content: 60.41

Gene sequence:

>687_bases
ATGATCGATAAATACGTGGCGTCCATCGATGCCGCCGTCGCCGATATTCCCGATGGCGCGACCATTATGGTCGGCGGTTT
TGGCCCGGCCGGTCAGCCCTATACGCTGCTGGACGCTTTGATCCGCCATCGGCCGCGCGGGCTAACGCTGATCAGCAACA
ACGCCGGTAACGGGGATTTTGGCTTGGCGGCGCTGTTAAAGGCCGGATGCGTGCGCAAGGTTGTCTGTTCATTCCCGCGC
CAGTCGGACTCCTGGGTATTTGATGACTTGTACCGCCGTGGCGAGCTGGAGCTGGAGCTGATCCCGCAGGGCAATCTGGC
GGCGCGCATTCAGGCCGCCGGTTCCGGGCTCGGCGGTTTTTACACCCCGACCGGCTATGGCACCGAACTGGCGCAAGGTA
AAGAAACGCGCGAGATCGACGGCAAACACTATGTGTTCGAGCTACCGCTGAAGGCGGATTTCGCGCTGATCAAGGCCGAT
AAAGCCGATCGCTGGGGTAACCTGCTGTACAACAAAACCGGGCGCAACTTTGGGCCGATTATGGCCATGGCCGCCGCCTG
CACCATTGCCGAAGTCAACCGCATGGTGCCGCTGGGTGAGTTGGATCCTGAAAATATCATTACGCCGGGGATCTTCGTGC
AACGCCTGGTGACTACACCCGATCACCCTGCGCCAGCGTCGGCTTAA

Upstream 100 bases:

>100_bases
CGCTGATATTCGCACTTGTCGCTGTTTTTTTCATCCCTTAAGGTAAATCCAGGCCCATAAGCGTCACGCAGAAATTACCG
TTGCGCAATCAGGAGAGCAG

Downstream 100 bases:

>100_bases
GGAGCGCCCCCATGACCAAACTTACACATCAACAGTTGGCCGAACGTATTGCCCGCGATATCCCGGAAGGTGCCTACGTC
AACCTGGGCATTGGGATCCC

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Beta-ketoadipate:succinyl-CoA transferase subunit A [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MIDKYVASIDAAVADIPDGATIMVGGFGPAGQPYTLLDALIRHRPRGLTLISNNAGNGDFGLAALLKAGCVRKVVCSFPR
QSDSWVFDDLYRRGELELELIPQGNLAARIQAAGSGLGGFYTPTGYGTELAQGKETREIDGKHYVFELPLKADFALIKAD
KADRWGNLLYNKTGRNFGPIMAMAAACTIAEVNRMVPLGELDPENIITPGIFVQRLVTTPDHPAPASA

Sequences:

>Translated_228_residues
MIDKYVASIDAAVADIPDGATIMVGGFGPAGQPYTLLDALIRHRPRGLTLISNNAGNGDFGLAALLKAGCVRKVVCSFPR
QSDSWVFDDLYRRGELELELIPQGNLAARIQAAGSGLGGFYTPTGYGTELAQGKETREIDGKHYVFELPLKADFALIKAD
KADRWGNLLYNKTGRNFGPIMAMAAACTIAEVNRMVPLGELDPENIITPGIFVQRLVTTPDHPAPASA
>Mature_228_residues
MIDKYVASIDAAVADIPDGATIMVGGFGPAGQPYTLLDALIRHRPRGLTLISNNAGNGDFGLAALLKAGCVRKVVCSFPR
QSDSWVFDDLYRRGELELELIPQGNLAARIQAAGSGLGGFYTPTGYGTELAQGKETREIDGKHYVFELPLKADFALIKAD
KADRWGNLLYNKTGRNFGPIMAMAAACTIAEVNRMVPLGELDPENIITPGIFVQRLVTTPDHPAPASA

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=224, Percent_Identity=45.0892857142857, Blast_Score=194, Evalue=4e-50,
Organism=Homo sapiens, GI11545841, Length=232, Percent_Identity=43.5344827586207, Blast_Score=178, Evalue=4e-45,
Organism=Escherichia coli, GI1788551, Length=208, Percent_Identity=42.3076923076923, Blast_Score=168, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17531517, Length=245, Percent_Identity=40.4081632653061, Blast_Score=177, Evalue=6e-45,
Organism=Drosophila melanogaster, GI21358325, Length=230, Percent_Identity=43.0434782608696, Blast_Score=177, Evalue=4e-45,
Organism=Drosophila melanogaster, GI24655794, Length=230, Percent_Identity=43.0434782608696, Blast_Score=177, Evalue=5e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.6 [H]

Molecular weight: Translated: 24417; Mature: 24417

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKYVASIDAAVADIPDGATIMVGGFGPAGQPYTLLDALIRHRPRGLTLISNNAGNGDF
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCH
GLAALLKAGCVRKVVCSFPRQSDSWVFDDLYRRGELELELIPQGNLAARIQAAGSGLGGF
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCC
YTPTGYGTELAQGKETREIDGKHYVFELPLKADFALIKADKADRWGNLLYNKTGRNFGPI
CCCCCCCCHHHCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCEECCCCCCHHHH
MAMAAACTIAEVNRMVPLGELDPENIITPGIFVQRLVTTPDHPAPASA
HHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MIDKYVASIDAAVADIPDGATIMVGGFGPAGQPYTLLDALIRHRPRGLTLISNNAGNGDF
CCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCCH
GLAALLKAGCVRKVVCSFPRQSDSWVFDDLYRRGELELELIPQGNLAARIQAAGSGLGGF
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCEEEEEECCCCCCCC
YTPTGYGTELAQGKETREIDGKHYVFELPLKADFALIKADKADRWGNLLYNKTGRNFGPI
CCCCCCCCHHHCCCCCCCCCCCEEEEECCCCCCEEEEECCCCCCCCCCEECCCCCCHHHH
MAMAAACTIAEVNRMVPLGELDPENIITPGIFVQRLVTTPDHPAPASA
HHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1624453; 6780551 [H]